메뉴 건너뛰기




Volumn 43, Issue 10, 2011, Pages 687-692

Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species

Author keywords

antioxidants; glucose; nutrition

Indexed keywords

AGAR; ANTIOXIDANT; LONIDAMINE; MITOGEN ACTIVATED PROTEIN KINASE P38; PARAQUAT; REACTIVE OXYGEN METABOLITE;

EID: 80052970130     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0031-1286308     Document Type: Article
Times cited : (27)

References (57)
  • 1
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman DB, Johnson TE. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics: 1988; 118 75 86 (Pubitemid 18038078)
    • (1988) Genetics , vol.118 , Issue.1 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 2
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • DOI 10.1038/366461a0
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature: 1993; 366 461 464 (Pubitemid 24013878)
    • (1993) Nature , vol.366 , Issue.6454 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 4
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • DOI 10.1126/science.277.5328.942
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science: 1997; 277 942 946 (Pubitemid 27366677)
    • (1997) Science , vol.277 , Issue.5328 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 5
    • 0035815414 scopus 로고    scopus 로고
    • Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    • DOI 10.1126/science.1057991
    • Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science: 2001; 292 104 106 (Pubitemid 32289136)
    • (2001) Science , vol.292 , Issue.5514 , pp. 104-106
    • Clancy, D.J.1    Gems, D.2    Harshman, L.G.3    Oldham, S.4    Stocker, H.5    Hafen, E.6    Leevers, S.J.7    Partridge, L.8
  • 6
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • DOI 10.1126/science.1057987
    • Tatar M, Kopelman A, Epstein D, Tu MP, Yin CM, Garofalo RS. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science: 2001; 292 107 110 (Pubitemid 32289137)
    • (2001) Science , vol.292 , Issue.5514 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.-P.4    Yin, C.-M.5    Garofalo, R.S.6
  • 7
    • 0347664057 scopus 로고    scopus 로고
    • IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
    • DOI 10.1038/nature01298
    • Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature: 2003; 421 182 187 (Pubitemid 36090987)
    • (2003) Nature , vol.421 , Issue.6919 , pp. 182-187
    • Holzenberger, M.1    Dupont, J.2    Ducos, B.3    Leneuve, P.4    Geloen, A.5    Even, P.C.6    Cervera, P.7    Le Bouc, Y.8
  • 8
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • DOI 10.1126/science.1078223
    • Blher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science: 2003; 299 572 574 (Pubitemid 36135156)
    • (2003) Science , vol.299 , Issue.5606 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 12
    • 76549104638 scopus 로고    scopus 로고
    • Resveratrol and rapamycin: Are they anti-aging drugs
    • Kaeberlein M. Resveratrol and rapamycin: are they anti-aging drugs? Bioessays: 2010; 32 96 99
    • (2010) Bioessays , vol.32 , pp. 96-99
    • Kaeberlein, M.1
  • 14
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • DOI 10.1038/nature02789
    • Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature: 2004; 430 686 689 (Pubitemid 39061685)
    • (2004) Nature , vol.430 , Issue.7000 , pp. 686-689
    • Wood, J.G.1    Regina, B.2    Lavu, S.3    Hewitz, K.4    Helfand, S.L.5    Tatar, M.6    Sinclair, D.7
  • 17
    • 78649329125 scopus 로고    scopus 로고
    • Differential Effects of Resveratrol and SRT1720 on Lifespan of Adult Caenorhabditis elegans
    • Zarse K, Schmeisser S, Birringer M, Falk E, Schmoll D, Ristow M. Differential Effects of Resveratrol and SRT1720 on Lifespan of Adult Caenorhabditis elegans. Horm Metab Res: 2010; 42 837 839
    • (2010) Horm Metab Res , vol.42 , pp. 837-839
    • Zarse, K.1    Schmeisser, S.2    Birringer, M.3    Falk, E.4    Schmoll, D.5    Ristow, M.6
  • 18
    • 34748850786 scopus 로고    scopus 로고
    • Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
    • DOI 10.1016/j.cmet.2007.08.011, PII S1550413107002562
    • Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab: 2007; 6 280 293 (Pubitemid 47468090)
    • (2007) Cell Metabolism , vol.6 , Issue.4 , pp. 280-293
    • Schulz, T.J.1    Zarse, K.2    Voigt, A.3    Urban, N.4    Birringer, M.5    Ristow, M.6
  • 20
    • 0022476635 scopus 로고
    • Inhibitory action of the antitumor agent lonidamine on mitochondrial respiration of Trypanosoma cruzi and T. brucei
    • DOI 10.1016/0166-6851(86)90104-0
    • Turrens JF. Inhibitory action of the antitumor agent lonidamine on mitochondrial respiration of Trypanosoma cruzi and T. brucei. Mol Biochem Parasitol: 1986; 20 237 241 (Pubitemid 16011628)
    • (1986) Molecular and Biochemical Parasitology , vol.20 , Issue.3 , pp. 237-241
    • Turrens, J.F.1
  • 24
    • 32244436232 scopus 로고    scopus 로고
    • Mitochondria: A target for cancer therapy
    • DOI 10.1038/sj.bjp.0706556, PII 0706556
    • Armstrong JS. Mitochondria: a target for cancer therapy. Br J Pharmacol: 2006; 147 239 248 (Pubitemid 43214681)
    • (2006) British Journal of Pharmacology , vol.147 , Issue.3 , pp. 239-248
    • Armstrong, J.S.1
  • 28
    • 0026446255 scopus 로고
    • Enhancement of cisplatin activity by lonidamine in human ovarian cancer cells
    • Silvestrini R, Zaffaroni N, Villa R, Orlandi L, Costa A. Enhancement of cisplatin activity by lonidamine in human ovarian cancer cells. Int J Cancer: 1992; 52 813 817
    • (1992) Int J Cancer , vol.52 , pp. 813-817
    • Silvestrini, R.1    Zaffaroni, N.2    Villa, R.3    Orlandi, L.4    Costa, A.5
  • 29
    • 0029861250 scopus 로고    scopus 로고
    • Effects of the inhibitors of energy metabolism, lonidamine and levamisole, on 5-aminolevulinic-acid-induced photochemotherapy
    • DOI 10.1002/(SICI)1097-0215(19960917)67:6<791::AID-IJC7>3.0.CO;2-M
    • Shevchuk I, Chekulayev V, Moan J, Berg K. Effects of the inhibitors of energy metabolism, lonidamine and levamisole, on 5-aminolevulinic-acid-induced photochemotherapy. Int J Cancer: 1996; 67 791 799 (Pubitemid 26348807)
    • (1996) International Journal of Cancer , vol.67 , Issue.6 , pp. 791-799
    • Shevchuk, I.1    Chekulayev, V.2    Moan, J.3    Berg, K.4
  • 30
    • 0019457193 scopus 로고
    • Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells
    • Floridi A, Paggi MG, Marcante ML, Silvestrini B, Caputo A, De Martino C. Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells. J Natl Cancer Inst: 1981; 66 497 499 (Pubitemid 11098551)
    • (1981) Journal of the National Cancer Institute , vol.66 , Issue.3 , pp. 497-499
    • Floridi, A.1    Paggi, M.G.2    Marcante, M.L.3
  • 31
    • 0023858514 scopus 로고
    • Lonidamine-induced, pH dependent inhibition of cellular oxygen utilization
    • Stryker JA, Gerweck LE. Lonidamine-induced, pH dependent inhibition of cellular oxygen utilization. Radiat Res: 1988; 113 356 361 (Pubitemid 18048887)
    • (1988) Radiation Research , vol.113 , Issue.2 , pp. 356-361
    • Stryker, J.A.1    Gerweck, L.E.2
  • 32
    • 0020519825 scopus 로고
    • Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria
    • Floridi A, Lehninger AL. Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria. Arch Biochem Biophys: 1983; 226 73 83 (Pubitemid 13022186)
    • (1983) Archives of Biochemistry and Biophysics , vol.226 , Issue.1 , pp. 73-83
    • Floridi, A.1    Lehninger, A.L.2
  • 33
    • 0035891212 scopus 로고    scopus 로고
    • Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437
    • DOI 10.1038/sj/onc/1204953
    • Belzacq AS, El Hamel C, Vieira HL, Cohen I, Haouzi D, Metivier D, Marchetti P, Brenner C, Kroemer G. Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437. Oncogene: 2001; 20 7579 7587 (Pubitemid 33111858)
    • (2001) Oncogene , vol.20 , Issue.52 , pp. 7579-7587
    • Belzacq, A.-S.1    El Hamel, C.2    Vieira, H.L.A.3    Cohen, I.4    Haouzi, D.5    Metivier, D.6    Marchetti, P.7    Brenner, C.8    Kroemer, G.9
  • 35
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • DOI 10.1038/35048073
    • Zamzami N, Kroemer G. The mitochondrion in apoptosis: how Pandoras box opens. Nat Rev Mol Cell Biol: 2001; 2 67 71 (Pubitemid 33676964)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.1 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 37
    • 65449119234 scopus 로고    scopus 로고
    • Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate
    • Chen Z, Zhang H, Lu W, Huang P. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim Biophys Acta: 2009; 1787 553 560
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 553-560
    • Chen, Z.1    Zhang, H.2    Lu, W.3    Huang, P.4
  • 38
    • 38849179467 scopus 로고    scopus 로고
    • A cell-based high-throughput assay system reveals modulation of oxidative and nonoxidative glucose metabolism due to commonly used organic solvents
    • DOI 10.1055/s-2007-1004542
    • Zimmermann S, Zarse K, Schulz TJ, Siems K, Mller-Kuhrt L, Birringer M, Ristow M. A cell-based high-throughput assay system reveals modulation of oxidative and non-oxidative glucose metabolism due to commonly used organic solvents. Horm Metab Res: 2008; 40 29 37 (Pubitemid 351204822)
    • (2008) Hormone and Metabolic Research , vol.40 , Issue.1 , pp. 29-37
    • Zimmermann, S.1    Zarse, K.2    Schulz, T.J.3    Siems, K.4    Muller-Kuhrt, L.5    Birringer, M.6    Ristow, M.7
  • 39
    • 58149178553 scopus 로고    scopus 로고
    • Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans
    • Zarse K, Ristow M. Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans. PLoS ONE: 2008; 3 e4062
    • (2008) PLoS ONE , vol.3
    • Zarse, K.1    Ristow, M.2
  • 40
    • 70350676299 scopus 로고    scopus 로고
    • Deceptively simple but simply deceptive -Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects
    • Gruber J, Ng LF, Poovathingal SK, Halliwell B. Deceptively simple but simply deceptive -Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects. FEBS Lett: 2009; 583 3377 3387
    • (2009) FEBS Lett , vol.583 , pp. 3377-3387
    • Gruber, J.1    Ng, L.F.2    Poovathingal, S.K.3    Halliwell, B.4
  • 41
    • 0029073748 scopus 로고
    • Mechanism of action of the antineoplastic drug lonidamine: 31P and 13C nuclear magnetic resonance studies
    • Ben-Horin H, Tassini M, Vivi A, Navon G, Kaplan O. Mechanism of action of the antineoplastic drug lonidamine: 31P and 13C nuclear magnetic resonance studies. Cancer Res: 1995; 55 2814 2821
    • (1995) Cancer Res , vol.55 , pp. 2814-2821
    • Ben-Horin, H.1    Tassini, M.2    Vivi, A.3    Navon, G.4    Kaplan, O.5
  • 42
    • 0027357520 scopus 로고
    • Oxygen radicals, a failure or a success of evolution
    • Barja G. Oxygen radicals, a failure or a success of evolution? Free Radic Res Commun: 1993; 18 63 70
    • (1993) Free Radic Res Commun , vol.18 , pp. 63-70
    • Barja, G.1
  • 44
    • 24144467846 scopus 로고    scopus 로고
    • ROS: Really involved in Oxygen Sensing
    • DOI 10.1016/j.cmet.2005.05.006, PII S1550413105001440
    • Kaelin WG Jr. ROS: really involved in oxygen sensing. Cell Metab: 2005; 1 357 358 (Pubitemid 43960628)
    • (2005) Cell Metabolism , vol.1 , Issue.6 , pp. 357-358
    • Kaelin Jr., W.G.1
  • 46
    • 24144493814 scopus 로고    scopus 로고
    • Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
    • DOI 10.1016/j.cmet.2005.05.001, PII S1550413105001397
    • Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab: 2005; 1 401 408 (Pubitemid 43960623)
    • (2005) Cell Metabolism , vol.1 , Issue.6 , pp. 401-408
    • Guzy, R.D.1    Hoyos, B.2    Robin, E.3    Chen, H.4    Liu, L.5    Mansfield, K.D.6    Simon, M.C.7    Hammerling, U.8    Schumacker, P.T.9
  • 47
    • 33747596652 scopus 로고    scopus 로고
    • Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
    • DOI 10.1113/expphysiol.2006.033506
    • Guzy RD, Schumacker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol: 2006; 91 807 819 (Pubitemid 44266577)
    • (2006) Experimental Physiology , vol.91 , Issue.5 , pp. 807-819
    • Guzy, R.D.1    Schumacker, P.T.2
  • 48
    • 33845741242 scopus 로고    scopus 로고
    • The cellular basis for diverse responses to oxygen
    • DOI 10.1016/j.freeradbiomed.2006.10.048, PII S0891584906006940
    • Chandel NS, Budinger GR. The cellular basis for diverse responses to oxygen. Free Radic Biol Med: 2007; 42 165 174 (Pubitemid 44970533)
    • (2007) Free Radical Biology and Medicine , vol.42 , Issue.2 , pp. 165-174
    • Chandel, N.S.1    Budinger, G.R.S.2
  • 49
    • 34147210988 scopus 로고    scopus 로고
    • Hydrogen Peroxide Sensing and Signaling
    • DOI 10.1016/j.molcel.2007.03.016, PII S1097276507001864
    • Veal EA, Day AM, Morgan BA. Hydrogen peroxide sensing and signaling. Mol Cell: 2007; 26 1 14 (Pubitemid 46578115)
    • (2007) Molecular Cell , vol.26 , Issue.1 , pp. 1-14
    • Veal, E.A.1    Day, A.M.2    Morgan, B.A.3
  • 50
    • 39749104169 scopus 로고    scopus 로고
    • Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
    • DOI 10.1038/ng.2007.50, PII NG200750
    • Owusu-Ansah E, Yavari A, Mandal S, Banerjee U. Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint. Nat Genet: 2008; 40 356 361 (Pubitemid 351311760)
    • (2008) Nature Genetics , vol.40 , Issue.3 , pp. 356-361
    • Owusu-Ansah, E.1    Yavari, A.2    Mandal, S.3    Banerjee, U.4
  • 51
    • 66049087696 scopus 로고    scopus 로고
    • The coordination of nuclear and mitochondrial communication during aging and calorie restriction
    • Finley LW, Haigis MC. The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev: 2009; 8 173 188
    • (2009) Ageing Res Rev , vol.8 , pp. 173-188
    • Finley, L.W.1    Haigis, M.C.2
  • 54
    • 78650177082 scopus 로고    scopus 로고
    • Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity
    • Lee SJ, Hwang AB, Kenyon C. Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity. Curr Biol: 2010; 20 2131 2136
    • (2010) Curr Biol , vol.20 , pp. 2131-2136
    • Lee, S.J.1    Hwang, A.B.2    Kenyon, C.3
  • 55
    • 78650455712 scopus 로고    scopus 로고
    • A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
    • Yang W, Hekimi S. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol: 2010; 8 e1000556
    • (2010) PLoS Biol , vol.8
    • Yang, W.1    Hekimi, S.2
  • 56
    • 78650945994 scopus 로고    scopus 로고
    • Mitochondrial stress signals revise an old aging theory
    • Woo DK, Shadel GS. Mitochondrial stress signals revise an old aging theory. Cell: 2011; 144 11 12
    • (2011) Cell , vol.144 , pp. 11-12
    • Woo, D.K.1    Shadel, G.S.2
  • 57
    • 79959350253 scopus 로고    scopus 로고
    • Extending life span by increasing oxidative stress
    • Ristow M, Schmeisser S. Extending life span by increasing oxidative stress. Free Radic Biol Med: 2011; 51 327 336
    • (2011) Free Radic Biol Med , vol.51 , pp. 327-336
    • Ristow, M.1    Schmeisser, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.