The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner

European Journal of Immunology

Volumn 44, Issue 12, 2014, Pages 3696-3707

  Tsuchiya, Kohsuke ^a   Hara, Hideki ^a   Fang, Rendong ^a   Hernandez Cuellar, Eduardo ^a   Sakai, Shunsuke ^a   Daim, Sylvia ^a   Chen, Xi ^a   Dewamitta, Sita R ^a   Qu, Huixin ^a   Mitsuyama, Masao ^a,b   Kawamura, Ikuo ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

ASC; Caspase 1; IL 18; Inflammasome; Listeria monocytogenes

Indexed keywords

ADAPTOR PROTEIN; APPOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; CYTOKINE; INFLAMMASOME; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; SERINE PROTEINASE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; IL10 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BACTERIAL INFECTION; BLOOD LEVEL; CELL MATURATION; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME ACTIVITY; HOST PATHOGEN INTERACTION; HOST RESISTANCE; LETHAL DOSE; LISTERIA MONOCYTOGENES; LISTERIOSIS; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SERUM; ANIMAL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; INFLAMMASOMES; INTERLEUKIN-10; INTERLEUKIN-18; LISTERIA MONOCYTOGENES; LISTERIOSIS; MICE; MICE, KNOCKOUT; NEUTROPHILS; RECEPTORS, INTERLEUKIN-10; SERINE PROTEASES;

EID: 84924308153     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201444673     Document Type: Article

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