Elevation of IL-18 in human sepsis

Journal of Clinical Immunology

Volumn 20, Issue 3, 2000, Pages 212-215

  Grobmyer, Stephen R ^a   Lin, Edward ^b   Lowry, Stephen F ^b   Rivadeneira, David E ^a   Potter, Strite ^a   Barie, Philip S ^a   Nathan, Carl F ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Cytokines; Endotoxemia; Human; IL 18; Sepsis

Indexed keywords

INTERLEUKIN 18;

ADULT; ARTICLE; CLINICAL ARTICLE; DIAGNOSTIC VALUE; ENDOTOXEMIA; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOSTIMULATION; INTENSIVE CARE; MALE; PRIORITY JOURNAL; SEPSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-18; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; SEPSIS;

EID: 0033944073     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006641630904     Document Type: Article

References (19)

1. Interleukin-18: Perspectives on the newest interleukin
2. Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
3. A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock
4. Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells. Synergism with interleukin-12 for interferon-gamma production
5. Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells
6. Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures
7. Cloning of a new cytokine that induces IFN-gamma production by T cells
8. Defective NK cell activity and Th1 response in IL-18-deficient mice
9. Ischemia/ reperfusion-induced IFN-gamma up-regulation: Involvement of IL-12 and IL-18
10. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia
11. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
12. Prospective comparison of two multiple organ dysfunction/failure scoring systems for prediction of mortality in critical surgical illness
13. Secretory leukocyte protcase inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia
14. Characterization of anti-human interleukin-18 (IL-18)/interferon-gamma-inducing factor (IGIF) monoclonal antibodies and their application in the measurement of human IL-18 by ELISA
15. Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1 beta are differentially regulated in human blood mononuclear cells and mouse spleen cells
16. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure
17. Biologic control of injury and inflammation: Much more than too little or too late
18. Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock
19. Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response