The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria

Journal of Immunology

Volumn 187, Issue 3, 2011, Pages 1333-1346

  Ghose, Purnima ^a   Ali, Asim Q ^a   Fang, Rong ^b   Forbes, Digna ^a   Ballard, Billy ^a   Ismail, Nahed ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 18 RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL IMMUNITY; BACTERIAL LOAD; BACTERIAL VIRULENCE; CD8+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EHRLICHIA; EHRLICHIA MURIS; EHRLICHIOSIS; FEMALE; HOST CELL; HOST PATHOGEN INTERACTION; INFECTION RESISTANCE; INTRACELLULAR BACTERIUM; IXODES OVATUS EHRLICHIA; LEUKOCYTE; LIVER INJURY; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEPTIC SHOCK; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ADAPTIVE IMMUNITY; ANIMALS; CELL DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; EHRLICHIOSIS; FEMALE; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; INTRACELLULAR FLUID; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NATURAL KILLER T-CELLS; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 80051648093     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100092     Document Type: Article

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