Crystal structure of the V(D)J recombinase RAG1-RAG2

Nature

Volumn 518, Issue 7540, 2015, Pages 507-511

  Kim, Min Sung ^a   Lapkouski, Mikalai ^a,b,c   Yang, Wei ^a   Gellert, Martin ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c DESY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; RAG1 PROTEIN; RAG2 PROTEIN; TRANSPOSASE; DNA; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; RAG-1 PROTEIN; RECOMBINASE; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

BIOCHEMISTRY; CRYSTAL STRUCTURE; EVOLUTIONARY BIOLOGY; IMMUNE SYSTEM; PROTEIN; RECOMBINATION; RODENT;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DNA BINDING; DNA CLEAVAGE; DNA PROTEIN COMPLEX; DNA STRUCTURE; GENE IDENTIFICATION; GENE MUTATION; GENE REARRANGEMENT; GENETIC ANALYSIS; GENETIC CONSERVATION; HUMAN; NONHUMAN; OMENN SYNDROME; POPULATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; SEVERE COMBINED IMMUNODEFICIENCY; STRUCTURE ANALYSIS; VDJ RECOMBINATION; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOUSE; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; X LINKED SEVERE COMBINED IMMUNODEFICIENCY; X RAY CRYSTALLOGRAPHY;

VERTEBRATA;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MODELS, MOLECULAR; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SEVERE COMBINED IMMUNODEFICIENCY; TRANSPOSASES; VDJ RECOMBINASES; X-LINKED COMBINED IMMUNODEFICIENCY DISEASES;

EID: 84924052353     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14174     Document Type: Article

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