Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice

International Immunopharmacology

Volumn 25, Issue 2, 2015, Pages 406-415

  Cheng, Haibo ^a   Bo, Yun ^b   Shen, Weixing ^a   Tan, Jiani ^a   Jia, Zhirong ^a   Xu, Changliang ^a   Li, Furong ^c  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fibrosis; Leonurine; Nephroprotective effect; NF B; TGF ; UUO

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEONURINE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; ANTIINFLAMMATORY AGENT; CYTOKINE; GALLIC ACID; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; KIDNEY FIBROSIS; MOUSE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; URETER OBSTRUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; EPITHELIAL MESENCHYMAL TRANSITION; FIBROSIS; KIDNEY; KIDNEY DISEASES; METABOLISM; PATHOLOGY; URETHRAL OBSTRUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; DISEASE MODELS, ANIMAL; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; GALLIC ACID; KIDNEY; KIDNEY DISEASES; MICE, INBRED C57BL; NF-KAPPA B; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; URETHRAL OBSTRUCTION;

EID: 84923925336     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.02.023     Document Type: Article

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