Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: Involvement of reactive oxygen species and NF-κB pathways

European Journal of Pharmacology

Volumn 680, Issue 1-3, 2012, Pages 108-114

  Liu, Xin Hua ^a   Pan, Li Long ^a   Yang, He Bei ^a   Gong, Qi Hai ^a   Zhu, Yi Zhun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Endothelial dysfunction; Heme oxygenase 1; Leonurine; Nuclear factor B; Reactive oxygen species

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LEONURINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHEMOKINE CCL2; CYCLOOXYGENASE 2; E-SELECTIN; ENDOTHELIUM, VASCULAR; GALLIC ACID; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; LIPOPOLYSACCHARIDES; NF-KAPPA B; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84862787904     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.012     Document Type: Article

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