Palmitate-induced impairments of β-cell function are linked with generation of specific ceramide species via acylation of sphingosine

Endocrinology (United States)

Volumn 156, Issue 3, 2015, Pages 802-812

  Manukyan, Levon ^a,b   Ubhayasekera, Sarojini J K A ^a,b   Bergquist, Jonas ^a,b   Sargsyan, Ernest ^a,b   Bergsten, Peter ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CERAMIDE; FUMONISIN B1; MESSENGER RNA; OLEIC ACID; PALMITIC ACID; SERINE PALMITOYLTRANSFERASE; SMALL INTERFERING RNA; SPHINGOSINE; THERMOZYMOCIDIN; INSULIN; PALMITIC ACID DERIVATIVE;

ACYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; HUMAN; HUMAN TISSUE; INSULIN RELEASE; MIN6 CELL LINE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; UPREGULATION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ACYLATION; ANIMALS; CELL LINE; CERAMIDES; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; OLEIC ACID; PALMITATES; SPHINGOSINE;

EID: 84923886912     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1467     Document Type: Article

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