Glucolipotoxicity in INS-1E cells is counteracted by carnitine palmitoyltransferase 1 over-expression

Biochemical and Biophysical Research Communications

Volumn 375, Issue 4, 2008, Pages 517-521

  Sol, E ri Maria ^a   Sargsyan, Ernest ^a   Akusjärvi, Göran ^a   Bergsten, Peter ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Apoptosis; Carnitine palmitoyltransferase 1; CHOP GADD153; ER stress; Glucolipotoxicity; GSIS; INS 1E; p eIF2 ; Palmitate; Type 2 diabetes

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITYLTRANSFERASE 1; ESSENTIAL FATTY ACID; GLUCOSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; PALMITIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CELLULAR STRESS RESPONSE; CYTOTOXICITY; FATTY ACID TRANSPORT; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLUCOLIPOTOXICITY; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; RAT; UPREGULATION;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CARNITINE O-PALMITOYLTRANSFERASE; CELL LINE; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FATTY ACIDS, NONESTERIFIED; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; PALMITATES; RATS; TRANSCRIPTION FACTOR CHOP;

ADENOVIRIDAE;

EID: 51449086879     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.08.013     Document Type: Article

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