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Volumn 24, Issue 11, 2014, Pages 651-663

Long noncoding RNAs: An emerging link between gene regulation and nuclear organization

Author keywords

Chromatin regulation; Genome organization; Long noncoding RNA (lncRNA); Nuclear domains

Indexed keywords

GENOMIC DNA; LONG UNTRANSLATED RNA; POLYCOMB REPRESSIVE COMPLEX 2; CHROMATIN; DNA;

EID: 84923638273     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2014.08.009     Document Type: Review
Times cited : (277)

References (135)
  • 1
    • 84876838711 scopus 로고    scopus 로고
    • The hierarchy of the 3D genome
    • Gibcus J.H., Dekker J. The hierarchy of the 3D genome. Mol. Cell 2013, 49:773-782.
    • (2013) Mol. Cell , vol.49 , pp. 773-782
    • Gibcus, J.H.1    Dekker, J.2
  • 2
    • 84875200698 scopus 로고    scopus 로고
    • Functional implications of genome topology
    • Cavalli G., Misteli T. Functional implications of genome topology. Nat. Struct. Mol. Biol. 2013, 20:290-299.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 290-299
    • Cavalli, G.1    Misteli, T.2
  • 3
    • 33847077659 scopus 로고    scopus 로고
    • Beyond the sequence: cellular organization of genome function
    • Misteli T. Beyond the sequence: cellular organization of genome function. Cell 2007, 128:787-800.
    • (2007) Cell , vol.128 , pp. 787-800
    • Misteli, T.1
  • 4
    • 79960622503 scopus 로고    scopus 로고
    • Biogenesis and function of nuclear bodies
    • Mao Y.S., et al. Biogenesis and function of nuclear bodies. Trends Genet. 2011, 27:295-306.
    • (2011) Trends Genet. , vol.27 , pp. 295-306
    • Mao, Y.S.1
  • 5
    • 55849109584 scopus 로고    scopus 로고
    • The epigenetics of rRNA genes: from molecular to chromosome biology
    • McStay B., Grummt I. The epigenetics of rRNA genes: from molecular to chromosome biology. Annu. Rev. Cell Dev. Biol. 2008, 24:131-157.
    • (2008) Annu. Rev. Cell Dev. Biol. , vol.24 , pp. 131-157
    • McStay, B.1    Grummt, I.2
  • 6
    • 0029055194 scopus 로고
    • The nucleolus: an organelle formed by the act of building a ribosome
    • Melese T., Xue Z. The nucleolus: an organelle formed by the act of building a ribosome. Curr. Opin. Cell Biol. 1995, 7:319-324.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 319-324
    • Melese, T.1    Xue, Z.2
  • 7
    • 0041669439 scopus 로고    scopus 로고
    • Nuclear speckles: a model for nuclear organelles
    • Lamond A.I., Spector D.L. Nuclear speckles: a model for nuclear organelles. Nat. Rev. Mol. Cell Biol. 2003, 4:605-612.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 605-612
    • Lamond, A.I.1    Spector, D.L.2
  • 9
    • 0037039475 scopus 로고    scopus 로고
    • Paraspeckles: a novel nuclear domain
    • Fox A.H., et al. Paraspeckles: a novel nuclear domain. Curr. Biol. 2002, 12:13-25.
    • (2002) Curr. Biol. , vol.12 , pp. 13-25
    • Fox, A.H.1
  • 10
    • 73349090560 scopus 로고    scopus 로고
    • Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
    • Schoenfelder S., et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat. Genet. 2010, 42:53-61.
    • (2010) Nat. Genet. , vol.42 , pp. 53-61
    • Schoenfelder, S.1
  • 11
    • 84887835943 scopus 로고    scopus 로고
    • Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency
    • Wei Z., et al. Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency. Cell Stem Cell 2013, 13:36-47.
    • (2013) Cell Stem Cell , vol.13 , pp. 36-47
    • Wei, Z.1
  • 12
    • 85044016110 scopus 로고    scopus 로고
    • Myc dynamically and preferentially relocates to a transcription factory occupied by Igh
    • Osborne C.S., et al. Myc dynamically and preferentially relocates to a transcription factory occupied by Igh. PLoS Biol. 2007, 5:e192.
    • (2007) PLoS Biol. , vol.5 , pp. e192
    • Osborne, C.S.1
  • 13
    • 78651514974 scopus 로고    scopus 로고
    • Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila
    • Bantignies F., et al. Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila. Cell 2011, 144:214-226.
    • (2011) Cell , vol.144 , pp. 214-226
    • Bantignies, F.1
  • 14
    • 84892474589 scopus 로고    scopus 로고
    • Polycomb silencing: from linear chromatin domains to 3D chromosome folding
    • Cheutin T., Cavalli G. Polycomb silencing: from linear chromatin domains to 3D chromosome folding. Curr. Opin. Genet. Dev. 2014, 25C:30-37.
    • (2014) Curr. Opin. Genet. Dev. , vol.25 C , pp. 30-37
    • Cheutin, T.1    Cavalli, G.2
  • 15
    • 84861976397 scopus 로고    scopus 로고
    • Polycomb: a paradigm for genome organization from one to three dimensions
    • Delest A., et al. Polycomb: a paradigm for genome organization from one to three dimensions. Curr. Opin. Cell Biol. 2012, 24:405-414.
    • (2012) Curr. Opin. Cell Biol. , vol.24 , pp. 405-414
    • Delest, A.1
  • 16
    • 84856747483 scopus 로고    scopus 로고
    • Three-dimensional folding and functional organization principles of the Drosophila genome
    • Sexton T., et al. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 2012, 148:458-472.
    • (2012) Cell , vol.148 , pp. 458-472
    • Sexton, T.1
  • 17
    • 84879232679 scopus 로고    scopus 로고
    • Genome organization and long-range regulation of gene expression by enhancers
    • Smallwood A., Ren B. Genome organization and long-range regulation of gene expression by enhancers. Curr. Opin. Cell Biol. 2013, 25:387-394.
    • (2013) Curr. Opin. Cell Biol. , vol.25 , pp. 387-394
    • Smallwood, A.1    Ren, B.2
  • 18
    • 0017261391 scopus 로고
    • Message and non-message sequences adjacent to poly(A) in steady state heterogeneous nuclear RNA of HeLa cells
    • Herman R.C., et al. Message and non-message sequences adjacent to poly(A) in steady state heterogeneous nuclear RNA of HeLa cells. Cell 1976, 7:429-437.
    • (1976) Cell , vol.7 , pp. 429-437
    • Herman, R.C.1
  • 19
    • 0015949399 scopus 로고
    • Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cells
    • Perry R.P., et al. Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cells. J. Mol. Biol. 1974, 82:315-331.
    • (1974) J. Mol. Biol. , vol.82 , pp. 315-331
    • Perry, R.P.1
  • 20
    • 0016684620 scopus 로고
    • Metabolism of the polyadenylate sequence of nuclear RNA and messenger RNA in mammalian cells
    • Brawerman G., Diez J. Metabolism of the polyadenylate sequence of nuclear RNA and messenger RNA in mammalian cells. Cell 1975, 5:271-280.
    • (1975) Cell , vol.5 , pp. 271-280
    • Brawerman, G.1    Diez, J.2
  • 21
    • 0027930199 scopus 로고
    • In vivo analysis of the stability and transport of nuclear poly(A)+ RNA
    • Huang S., et al. In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J. Cell Biol. 1994, 126:877-899.
    • (1994) J. Cell Biol. , vol.126 , pp. 877-899
    • Huang, S.1
  • 22
    • 0025270026 scopus 로고
    • Core filaments of the nuclear matrix
    • He D.C., et al. Core filaments of the nuclear matrix. J. Cell Biol. 1990, 110:569-580.
    • (1990) J. Cell Biol. , vol.110 , pp. 569-580
    • He, D.C.1
  • 23
    • 0345892812 scopus 로고
    • Chromatin architecture and nuclear RNA
    • Nickerson J.A., et al. Chromatin architecture and nuclear RNA. Proc. Natl. Acad. Sci. U.S.A. 1989, 86:177-181.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 177-181
    • Nickerson, J.A.1
  • 24
    • 62249133709 scopus 로고    scopus 로고
    • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
    • Guttman M., et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009, 458:223-227.
    • (2009) Nature , vol.458 , pp. 223-227
    • Guttman, M.1
  • 25
    • 84857066786 scopus 로고    scopus 로고
    • Modular regulatory principles of large non-coding RNAs
    • Guttman M., Rinn J.L. Modular regulatory principles of large non-coding RNAs. Nature 2012, 482:339-346.
    • (2012) Nature , vol.482 , pp. 339-346
    • Guttman, M.1    Rinn, J.L.2
  • 26
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • Cabili M.N., et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 2011, 25:1915-1927.
    • (2011) Genes Dev. , vol.25 , pp. 1915-1927
    • Cabili, M.N.1
  • 27
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
    • Derrien T., et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012, 22:1775-1789.
    • (2012) Genome Res. , vol.22 , pp. 1775-1789
    • Derrien, T.1
  • 28
    • 84891757415 scopus 로고    scopus 로고
    • Multiple knockout mouse models reveal lincRNAs are required for life and brain development
    • Sauvageau M., et al. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife 2013, 2:e01749.
    • (2013) Elife , vol.2 , pp. e01749
    • Sauvageau, M.1
  • 29
    • 84455206362 scopus 로고    scopus 로고
    • Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
    • Ulitsky I., et al. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell 2011, 147:1537-1550.
    • (2011) Cell , vol.147 , pp. 1537-1550
    • Ulitsky, I.1
  • 30
    • 80052869283 scopus 로고    scopus 로고
    • LincRNAs act in the circuitry controlling pluripotency and differentiation
    • Guttman M., et al. lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 2011, 477:295-300.
    • (2011) Nature , vol.477 , pp. 295-300
    • Guttman, M.1
  • 31
    • 84873300214 scopus 로고    scopus 로고
    • Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
    • Klattenhoff C.A., et al. Braveheart, a long noncoding RNA required for cardiovascular lineage commitment. Cell 2013, 152:570-583.
    • (2013) Cell , vol.152 , pp. 570-583
    • Klattenhoff, C.A.1
  • 32
    • 84908020927 scopus 로고    scopus 로고
    • A long noncoding RNA protects the heart from pathological hypertrophy
    • Han P., et al. A long noncoding RNA protects the heart from pathological hypertrophy. Nature 2014, http://dx.doi.org/10.1038/nature13596.
    • (2014) Nature
    • Han, P.1
  • 33
    • 77951118936 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    • Gupta R.A., et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010, 464:1071-1076.
    • (2010) Nature , vol.464 , pp. 1071-1076
    • Gupta, R.A.1
  • 34
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • Huarte M., et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 2010, 142:409-419.
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1
  • 35
    • 84883132550 scopus 로고    scopus 로고
    • LncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs
    • Yang L., et al. lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs. Nature 2013, 500:598-602.
    • (2013) Nature , vol.500 , pp. 598-602
    • Yang, L.1
  • 36
    • 84873451950 scopus 로고    scopus 로고
    • The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells
    • Gutschner T., et al. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Res. 2013, 73:1180-1189.
    • (2013) Cancer Res. , vol.73 , pp. 1180-1189
    • Gutschner, T.1
  • 37
    • 84905401266 scopus 로고    scopus 로고
    • Genome-wide mapping and characterization of notch-regulated long noncoding RNAs in acute leukemia
    • Trimarchi T., et al. Genome-wide mapping and characterization of notch-regulated long noncoding RNAs in acute leukemia. Cell 2014, 158:593-606.
    • (2014) Cell , vol.158 , pp. 593-606
    • Trimarchi, T.1
  • 38
    • 67650921949 scopus 로고    scopus 로고
    • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
    • Khalil A.M., et al. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:11667-11672.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 11667-11672
    • Khalil, A.M.1
  • 39
    • 80053045739 scopus 로고    scopus 로고
    • Molecular mechanisms of long noncoding RNAs
    • Wang K.C., Chang H.Y. Molecular mechanisms of long noncoding RNAs. Mol. Cell 2011, 43:904-914.
    • (2011) Mol. Cell , vol.43 , pp. 904-914
    • Wang, K.C.1    Chang, H.Y.2
  • 40
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • Rinn J.L., Chang H.Y. Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 2012, 81:145-166.
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 41
    • 84884582059 scopus 로고    scopus 로고
    • Long non-coding RNAs: modulators of nuclear structure and function
    • Bergmann J.H., Spector D.L. Long non-coding RNAs: modulators of nuclear structure and function. Curr. Opin. Cell Biol. 2014, 26:10-18.
    • (2014) Curr. Opin. Cell Biol. , vol.26 , pp. 10-18
    • Bergmann, J.H.1    Spector, D.L.2
  • 42
    • 78650511795 scopus 로고    scopus 로고
    • Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs
    • Mao Y.S., et al. Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs. Nat. Cell Biol. 2011, 13:95-101.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 95-101
    • Mao, Y.S.1
  • 43
    • 62549117314 scopus 로고    scopus 로고
    • An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
    • Clemson C.M., et al. An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol. Cell 2009, 33:717-726.
    • (2009) Mol. Cell , vol.33 , pp. 717-726
    • Clemson, C.M.1
  • 44
    • 84879642373 scopus 로고    scopus 로고
    • The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
    • Engreitz J.M., et al. The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science 2013, 341:1237973.
    • (2013) Science , vol.341 , pp. 1237973
    • Engreitz, J.M.1
  • 45
    • 84893767092 scopus 로고    scopus 로고
    • Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
    • Hacisuleyman E., et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nat. Struct. Mol. Biol. 2014, 21:198-206.
    • (2014) Nat. Struct. Mol. Biol. , vol.21 , pp. 198-206
    • Hacisuleyman, E.1
  • 46
    • 84868629293 scopus 로고    scopus 로고
    • A misplaced lncRNA causes brachydactyly in humans
    • Maass P.G., et al. A misplaced lncRNA causes brachydactyly in humans. J. Clin. Invest. 2012, 122:3990-4002.
    • (2012) J. Clin. Invest. , vol.122 , pp. 3990-4002
    • Maass, P.G.1
  • 47
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • Wang K.C., et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 2011, 472:120-124.
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1
  • 48
    • 84897446230 scopus 로고    scopus 로고
    • Enhancer RNAs and regulated transcriptional programs
    • Lam M.T., et al. Enhancer RNAs and regulated transcriptional programs. Trends Biochem. Sci. 2014, 39:170-182.
    • (2014) Trends Biochem. Sci. , vol.39 , pp. 170-182
    • Lam, M.T.1
  • 49
    • 84902380512 scopus 로고    scopus 로고
    • Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1
    • Shichino Y., et al. Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1. Open Biol. 2014, 4:140022.
    • (2014) Open Biol. , vol.4 , pp. 140022
    • Shichino, Y.1
  • 50
    • 0037632867 scopus 로고    scopus 로고
    • The fission yeast meiotic regulator Mei2p forms a dot structure in the horse-tail nucleus in association with the sme2 locus on chromosome II
    • Shimada T., et al. The fission yeast meiotic regulator Mei2p forms a dot structure in the horse-tail nucleus in association with the sme2 locus on chromosome II. Mol. Biol. Cell 2003, 14:2461-2469.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2461-2469
    • Shimada, T.1
  • 51
    • 33746076412 scopus 로고    scopus 로고
    • A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced
    • Chaumeil J., et al. A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev. 2006, 20:2223-2237.
    • (2006) Genes Dev. , vol.20 , pp. 2223-2237
    • Chaumeil, J.1
  • 52
    • 0036948659 scopus 로고    scopus 로고
    • Xist RNA and the mechanism of X chromosome inactivation
    • Plath K., et al. Xist RNA and the mechanism of X chromosome inactivation. Annu. Rev. Genet. 2002, 36:233-278.
    • (2002) Annu. Rev. Genet. , vol.36 , pp. 233-278
    • Plath, K.1
  • 53
    • 0025961771 scopus 로고
    • A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
    • Brown C.J., et al. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 1991, 349:38-44.
    • (1991) Nature , vol.349 , pp. 38-44
    • Brown, C.J.1
  • 54
    • 0025727201 scopus 로고
    • Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome
    • Brockdorff N., et al. Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 1991, 351:329-331.
    • (1991) Nature , vol.351 , pp. 329-331
    • Brockdorff, N.1
  • 55
    • 0026489906 scopus 로고
    • The product of the mouse Xist gene is a 15kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
    • Brockdorff N., et al. The product of the mouse Xist gene is a 15kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 1992, 71:515-526.
    • (1992) Cell , vol.71 , pp. 515-526
    • Brockdorff, N.1
  • 56
    • 0030034051 scopus 로고    scopus 로고
    • XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure
    • Clemson C.M., et al. XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J. Cell Biol. 1996, 132:259-275.
    • (1996) J. Cell Biol. , vol.132 , pp. 259-275
    • Clemson, C.M.1
  • 57
    • 0030026001 scopus 로고    scopus 로고
    • Requirement for Xist in X chromosome inactivation
    • Penny G.D., et al. Requirement for Xist in X chromosome inactivation. Nature 1996, 379:131-137.
    • (1996) Nature , vol.379 , pp. 131-137
    • Penny, G.D.1
  • 58
    • 0035198727 scopus 로고    scopus 로고
    • Expression of Xist RNA is sufficient to initiate macrochromatin body formation
    • Rasmussen T.P., et al. Expression of Xist RNA is sufficient to initiate macrochromatin body formation. Chromosoma 2001, 110:411-420.
    • (2001) Chromosoma , vol.110 , pp. 411-420
    • Rasmussen, T.P.1
  • 59
    • 0033637110 scopus 로고    scopus 로고
    • A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
    • Wutz A., Jaenisch R. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol. Cell 2000, 5:695-705.
    • (2000) Mol. Cell , vol.5 , pp. 695-705
    • Wutz, A.1    Jaenisch, R.2
  • 60
    • 0036479009 scopus 로고    scopus 로고
    • Chromosomal silencing and localization are mediated by different domains of Xist RNA
    • Wutz A., et al. Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nat. Genet. 2002, 30:167-174.
    • (2002) Nat. Genet. , vol.30 , pp. 167-174
    • Wutz, A.1
  • 61
    • 84879198022 scopus 로고    scopus 로고
    • Imprinted silencing is extended over broad chromosomal domains in mouse extra-embryonic lineages
    • Kulinski T.M., et al. Imprinted silencing is extended over broad chromosomal domains in mouse extra-embryonic lineages. Curr. Opin. Cell Biol. 2013, 25:297-304.
    • (2013) Curr. Opin. Cell Biol. , vol.25 , pp. 297-304
    • Kulinski, T.M.1
  • 62
    • 24144456545 scopus 로고    scopus 로고
    • Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air
    • Yamasaki Y., et al. Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air. Hum. Mol. Genet. 2005, 14:2511-2520.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2511-2520
    • Yamasaki, Y.1
  • 63
    • 56549111129 scopus 로고    scopus 로고
    • The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin
    • Nagano T., et al. The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science 2008, 322:1717-1720.
    • (2008) Science , vol.322 , pp. 1717-1720
    • Nagano, T.1
  • 64
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • Rinn J.L., et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 2007, 129:1311-1323.
    • (2007) Cell , vol.129 , pp. 1311-1323
    • Rinn, J.L.1
  • 65
    • 80054756754 scopus 로고    scopus 로고
    • Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
    • Chu C., et al. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol. Cell 2011, 44:667-678.
    • (2011) Mol. Cell , vol.44 , pp. 667-678
    • Chu, C.1
  • 66
    • 84874500772 scopus 로고    scopus 로고
    • Long noncoding RNAs regulate adipogenesis
    • Sun L., et al. Long noncoding RNAs regulate adipogenesis. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:3387-3392.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 3387-3392
    • Sun, L.1
  • 67
    • 84881478367 scopus 로고    scopus 로고
    • A long noncoding RNA mediates both activation and repression of immune response genes
    • Carpenter S., et al. A long noncoding RNA mediates both activation and repression of immune response genes. Science 2013, 341:789-792.
    • (2013) Science , vol.341 , pp. 789-792
    • Carpenter, S.1
  • 68
    • 84899486799 scopus 로고    scopus 로고
    • The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
    • Wang P., et al. The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science 2014, 344:310-313.
    • (2014) Science , vol.344 , pp. 310-313
    • Wang, P.1
  • 69
    • 77957243921 scopus 로고    scopus 로고
    • Long noncoding RNAs with enhancer-like function in human cells
    • Orom U.A., et al. Long noncoding RNAs with enhancer-like function in human cells. Cell 2010, 143:46-58.
    • (2010) Cell , vol.143 , pp. 46-58
    • Orom, U.A.1
  • 70
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R., Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011, 469:343-349.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 71
    • 0034934749 scopus 로고    scopus 로고
    • Imprinted X inactivation maintained by a mouse Polycomb group gene
    • Wang J., et al. Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat. Genet. 2001, 28:371-375.
    • (2001) Nat. Genet. , vol.28 , pp. 371-375
    • Wang, J.1
  • 72
    • 0037172659 scopus 로고    scopus 로고
    • Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells
    • Mak W., et al. Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells. Curr. Biol. 2002, 12:1016-1020.
    • (2002) Curr. Biol. , vol.12 , pp. 1016-1020
    • Mak, W.1
  • 73
    • 0037387711 scopus 로고    scopus 로고
    • Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes
    • Silva J., et al. Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev. Cell 2003, 4:481-495.
    • (2003) Dev. Cell , vol.4 , pp. 481-495
    • Silva, J.1
  • 74
    • 84892866184 scopus 로고    scopus 로고
    • Jarid2 is implicated in the initial Xist-induced targeting of PRC2 to the inactive X chromosome
    • da Rocha S.T., et al. Jarid2 is implicated in the initial Xist-induced targeting of PRC2 to the inactive X chromosome. Mol. Cell 2014, 53:301-316.
    • (2014) Mol. Cell , vol.53 , pp. 301-316
    • da Rocha, S.T.1
  • 75
    • 55349109963 scopus 로고    scopus 로고
    • Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
    • Zhao J., et al. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science 2008, 322:750-756.
    • (2008) Science , vol.322 , pp. 750-756
    • Zhao, J.1
  • 76
    • 84904507962 scopus 로고    scopus 로고
    • Regulatory interactions between RNA and Polycomb Repressive Complex 2
    • Cifuentes-Rojas C., et al. Regulatory interactions between RNA and Polycomb Repressive Complex 2. Mol. Cell 2014, 55:171-185.
    • (2014) Mol. Cell , vol.55 , pp. 171-185
    • Cifuentes-Rojas, C.1
  • 77
    • 84893857700 scopus 로고    scopus 로고
    • Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy
    • Cerase A., et al. Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:2235-2240.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 2235-2240
    • Cerase, A.1
  • 78
    • 84875418596 scopus 로고    scopus 로고
    • Noncoding RNA and Polycomb recruitment
    • Brockdorff N. Noncoding RNA and Polycomb recruitment. RNA 2013, 19:429-442.
    • (2013) RNA , vol.19 , pp. 429-442
    • Brockdorff, N.1
  • 79
    • 0242668706 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in X inactivation
    • Plath K., et al. Role of histone H3 lysine 27 methylation in X inactivation. Science 2003, 300:131-135.
    • (2003) Science , vol.300 , pp. 131-135
    • Plath, K.1
  • 80
    • 33746407708 scopus 로고    scopus 로고
    • Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
    • Schoeftner S., et al. Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J. 2006, 25:3110-3122.
    • (2006) EMBO J. , vol.25 , pp. 3110-3122
    • Schoeftner, S.1
  • 81
    • 33646942973 scopus 로고    scopus 로고
    • The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation
    • Kalantry S., Magnuson T. The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet. 2006, 2:e66.
    • (2006) PLoS Genet. , vol.2 , pp. e66
    • Kalantry, S.1    Magnuson, T.2
  • 82
    • 78650253763 scopus 로고    scopus 로고
    • Genome-wide identification of polycomb-associated RNAs by RIP-seq
    • Zhao J., et al. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol. Cell 2010, 40:939-953.
    • (2010) Mol. Cell , vol.40 , pp. 939-953
    • Zhao, J.1
  • 83
    • 84892889808 scopus 로고    scopus 로고
    • Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin
    • Kaneko S., et al. Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin. Mol. Cell 2014, 53:290-300.
    • (2014) Mol. Cell , vol.53 , pp. 290-300
    • Kaneko, S.1
  • 84
    • 84898723075 scopus 로고    scopus 로고
    • Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency
    • Yang Y.W., et al. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife 2014, 3:e02046.
    • (2014) Elife , vol.3 , pp. e02046
    • Yang, Y.W.1
  • 85
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • Yap K.L., et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol. Cell 2010, 38:662-674.
    • (2010) Mol. Cell , vol.38 , pp. 662-674
    • Yap, K.L.1
  • 86
    • 81055140863 scopus 로고    scopus 로고
    • NcRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
    • Yang L., et al. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell 2011, 147:773-788.
    • (2011) Cell , vol.147 , pp. 773-788
    • Yang, L.1
  • 87
    • 77954572735 scopus 로고    scopus 로고
    • Long noncoding RNA as modular scaffold of histone modification complexes
    • Tsai M.C., et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science 2010, 329:689-693.
    • (2010) Science , vol.329 , pp. 689-693
    • Tsai, M.C.1
  • 88
    • 84887460647 scopus 로고    scopus 로고
    • PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells
    • Kaneko S., et al. PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Nat. Struct. Mol. Biol. 2013, 20:1258-1264.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 1258-1264
    • Kaneko, S.1
  • 89
    • 84887419464 scopus 로고    scopus 로고
    • Promiscuous RNA binding by Polycomb repressive complex 2
    • Davidovich C., et al. Promiscuous RNA binding by Polycomb repressive complex 2. Nat. Struct. Mol. Biol. 2013, 20:1250-1257.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 1250-1257
    • Davidovich, C.1
  • 90
    • 84892999996 scopus 로고    scopus 로고
    • Methods for comprehensive experimental identification of RNA-protein interactions
    • McHugh C.A., et al. Methods for comprehensive experimental identification of RNA-protein interactions. Genome Biol. 2014, 15:203.
    • (2014) Genome Biol. , vol.15 , pp. 203
    • McHugh, C.A.1
  • 91
    • 70350686180 scopus 로고    scopus 로고
    • SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
    • Bilodeau S., et al. SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev. 2009, 23:2484-2489.
    • (2009) Genes Dev. , vol.23 , pp. 2484-2489
    • Bilodeau, S.1
  • 92
    • 34249900454 scopus 로고    scopus 로고
    • The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
    • Tahiliani M., et al. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 2007, 447:601-605.
    • (2007) Nature , vol.447 , pp. 601-605
    • Tahiliani, M.1
  • 93
    • 43249102851 scopus 로고    scopus 로고
    • Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
    • Cloos P.A., et al. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev. 2008, 22:1115-1140.
    • (2008) Genes Dev. , vol.22 , pp. 1115-1140
    • Cloos, P.A.1
  • 94
    • 0035979173 scopus 로고    scopus 로고
    • PNA interference mapping demonstrates functional domains in the noncoding RNA Xist
    • Beletskii A., et al. PNA interference mapping demonstrates functional domains in the noncoding RNA Xist. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:9215-9220.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 9215-9220
    • Beletskii, A.1
  • 95
    • 78650675579 scopus 로고    scopus 로고
    • Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome
    • Sarma K., et al. Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:22196-22201.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 22196-22201
    • Sarma, K.1
  • 96
    • 0025743438 scopus 로고
    • Telomerase primer specificity and chromosome healing
    • Harrington L.A., Greider C.W. Telomerase primer specificity and chromosome healing. Nature 1991, 353:451-454.
    • (1991) Nature , vol.353 , pp. 451-454
    • Harrington, L.A.1    Greider, C.W.2
  • 97
    • 77958576363 scopus 로고    scopus 로고
    • Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes
    • Schmitz K.M., et al. Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev. 2010, 24:2264-2269.
    • (2010) Genes Dev. , vol.24 , pp. 2264-2269
    • Schmitz, K.M.1
  • 98
    • 84880445591 scopus 로고    scopus 로고
    • The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation
    • Soruco M.M., et al. The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation. Genes Dev. 2013, 27:1551-1556.
    • (2013) Genes Dev. , vol.27 , pp. 1551-1556
    • Soruco, M.M.1
  • 99
    • 84862908875 scopus 로고    scopus 로고
    • The genomic binding sites of a noncoding RNA
    • Simon M.D., et al. The genomic binding sites of a noncoding RNA. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:20497-20502.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 20497-20502
    • Simon, M.D.1
  • 100
    • 84873569148 scopus 로고    scopus 로고
    • Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila
    • Wang C.I., et al. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat. Struct. Mol. Biol. 2013, 20:202-209.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 202-209
    • Wang, C.I.1
  • 101
    • 77956607961 scopus 로고    scopus 로고
    • The matrix protein hnRNP U is required for chromosomal localization of Xist RNA
    • Hasegawa Y., et al. The matrix protein hnRNP U is required for chromosomal localization of Xist RNA. Dev. Cell 2010, 19:469-476.
    • (2010) Dev. Cell , vol.19 , pp. 469-476
    • Hasegawa, Y.1
  • 102
    • 84901008820 scopus 로고    scopus 로고
    • Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila
    • McElroy K.A., et al. Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila. Open Biol. 2014, 4:140006.
    • (2014) Open Biol. , vol.4 , pp. 140006
    • McElroy, K.A.1
  • 103
    • 84890549512 scopus 로고    scopus 로고
    • High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
    • Simon M.D., et al. High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation. Nature 2013, 504:465-469.
    • (2013) Nature , vol.504 , pp. 465-469
    • Simon, M.D.1
  • 104
    • 84906322449 scopus 로고    scopus 로고
    • Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification
    • Quinn J.J., et al. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nat. Biotechnol. 2014, 32:933-940.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 933-940
    • Quinn, J.J.1
  • 105
    • 77949919093 scopus 로고    scopus 로고
    • Interchromosomal association and gene regulation in trans
    • Williams A., et al. Interchromosomal association and gene regulation in trans. Trends Genet. 2010, 26:188-197.
    • (2010) Trends Genet. , vol.26 , pp. 188-197
    • Williams, A.1
  • 106
    • 85027929606 scopus 로고    scopus 로고
    • Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization
    • Denholtz M., et al. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell 2013, 13:602-616.
    • (2013) Cell Stem Cell , vol.13 , pp. 602-616
    • Denholtz, M.1
  • 107
    • 84899894562 scopus 로고    scopus 로고
    • Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci
    • Noordermeer D., et al. Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci. Elife 2014, 3:e02557.
    • (2014) Elife , vol.3 , pp. e02557
    • Noordermeer, D.1
  • 108
    • 61849113891 scopus 로고    scopus 로고
    • MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
    • Sunwoo H., et al. MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res. 2009, 19:347-359.
    • (2009) Genome Res. , vol.19 , pp. 347-359
    • Sunwoo, H.1
  • 109
    • 68949212914 scopus 로고    scopus 로고
    • Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA
    • Chen L.L., Carmichael G.G. Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. Mol. Cell 2009, 35:467-478.
    • (2009) Mol. Cell , vol.35 , pp. 467-478
    • Chen, L.L.1    Carmichael, G.G.2
  • 110
    • 79551593011 scopus 로고    scopus 로고
    • Nucleation of nuclear bodies by RNA
    • Shevtsov S.P., Dundr M. Nucleation of nuclear bodies by RNA. Nat. Cell Biol. 2011, 13:167-173.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 167-173
    • Shevtsov, S.P.1    Dundr, M.2
  • 111
    • 79959952919 scopus 로고    scopus 로고
    • The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
    • Splinter E., et al. The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA. Genes Dev. 2011, 25:1371-1383.
    • (2011) Genes Dev. , vol.25 , pp. 1371-1383
    • Splinter, E.1
  • 112
    • 0030895047 scopus 로고    scopus 로고
    • Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
    • Lee J.T., Jaenisch R. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nature 1997, 386:275-279.
    • (1997) Nature , vol.386 , pp. 275-279
    • Lee, J.T.1    Jaenisch, R.2
  • 113
    • 33846283384 scopus 로고    scopus 로고
    • Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions
    • Lanctot C., et al. Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat. Rev. Genet. 2007, 8:104-115.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 104-115
    • Lanctot, C.1
  • 114
    • 20444494936 scopus 로고    scopus 로고
    • Interchromosomal associations between alternatively expressed loci
    • Spilianakis C.G., et al. Interchromosomal associations between alternatively expressed loci. Nature 2005, 435:637-645.
    • (2005) Nature , vol.435 , pp. 637-645
    • Spilianakis, C.G.1
  • 115
    • 84874368349 scopus 로고    scopus 로고
    • Activating RNAs associate with mediator to enhance chromatin architecture and transcription
    • Lai F., et al. Activating RNAs associate with mediator to enhance chromatin architecture and transcription. Nature 2013, 494:497-501.
    • (2013) Nature , vol.494 , pp. 497-501
    • Lai, F.1
  • 116
    • 84879695128 scopus 로고    scopus 로고
    • Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
    • Li W., et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 2013, 498:516-520.
    • (2013) Nature , vol.498 , pp. 516-520
    • Li, W.1
  • 117
    • 84884220048 scopus 로고    scopus 로고
    • Long noncoding RNAs usher in a new era in the biology of enhancers
    • Orom U.A., Shiekhattar R. Long noncoding RNAs usher in a new era in the biology of enhancers. Cell 2013, 154:1190-1193.
    • (2013) Cell , vol.154 , pp. 1190-1193
    • Orom, U.A.1    Shiekhattar, R.2
  • 119
    • 0035889085 scopus 로고    scopus 로고
    • The concept of self-organization in cellular architecture
    • Misteli T. The concept of self-organization in cellular architecture. J. Cell Biol. 2001, 155:181-185.
    • (2001) J. Cell Biol. , vol.155 , pp. 181-185
    • Misteli, T.1
  • 120
    • 58149259990 scopus 로고    scopus 로고
    • De novo formation of a subnuclear body
    • Kaiser T.E., et al. De novo formation of a subnuclear body. Science 2008, 322:1713-1717.
    • (2008) Science , vol.322 , pp. 1713-1717
    • Kaiser, T.E.1
  • 121
    • 18744375181 scopus 로고    scopus 로고
    • Concepts in nuclear architecture
    • Misteli T. Concepts in nuclear architecture. Bioessays 2005, 27:477-487.
    • (2005) Bioessays , vol.27 , pp. 477-487
    • Misteli, T.1
  • 122
    • 0034717122 scopus 로고    scopus 로고
    • Like attracts like: getting RNA processing together in the nucleus
    • Lewis J.D., Tollervey D. Like attracts like: getting RNA processing together in the nucleus. Science 2000, 288:1385-1389.
    • (2000) Science , vol.288 , pp. 1385-1389
    • Lewis, J.D.1    Tollervey, D.2
  • 123
    • 84899922567 scopus 로고    scopus 로고
    • Identification of regulators of the three-dimensional polycomb organization by a microscopy-based genome-wide RNAi Screen
    • Gonzalez I., et al. Identification of regulators of the three-dimensional polycomb organization by a microscopy-based genome-wide RNAi Screen. Mol. Cell 2014, 54:485-499.
    • (2014) Mol. Cell , vol.54 , pp. 485-499
    • Gonzalez, I.1
  • 124
    • 84879643314 scopus 로고    scopus 로고
    • Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes
    • Schaaf C.A., et al. Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes. PLoS Genet. 2013, 9:e1003560.
    • (2013) PLoS Genet. , vol.9 , pp. e1003560
    • Schaaf, C.A.1
  • 125
    • 84895541597 scopus 로고    scopus 로고
    • Function of YY1 in long-distance DNA interactions
    • Atchison M.L. Function of YY1 in long-distance DNA interactions. Front. Immunol. 2014, 5:45.
    • (2014) Front. Immunol. , vol.5 , pp. 45
    • Atchison, M.L.1
  • 126
    • 84893155560 scopus 로고    scopus 로고
    • Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming
    • Zhang H., et al. Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming. Cell Stem Cell 2013, 13:30-35.
    • (2013) Cell Stem Cell , vol.13 , pp. 30-35
    • Zhang, H.1
  • 127
    • 84878860751 scopus 로고    scopus 로고
    • Architectural protein subclasses shape 3D organization of genomes during lineage commitment
    • Phillips-Cremins J.E., et al. Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell 2013, 153:1281-1295.
    • (2013) Cell , vol.153 , pp. 1281-1295
    • Phillips-Cremins, J.E.1
  • 128
    • 77952148742 scopus 로고    scopus 로고
    • Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs
    • Guttman M., et al. Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat. Biotechnol. 2010, 28:503-510.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 503-510
    • Guttman, M.1
  • 129
    • 73849145104 scopus 로고    scopus 로고
    • A global view of protein expression in human cells, tissues, and organs
    • Ponten F., et al. A global view of protein expression in human cells, tissues, and organs. Mol. Syst. Biol. 2009, 5:337.
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 337
    • Ponten, F.1
  • 130
    • 7044272280 scopus 로고    scopus 로고
    • Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses
    • Mili S., Steitz J.A. Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses. RNA 2004, 10:1692-1694.
    • (2004) RNA , vol.10 , pp. 1692-1694
    • Mili, S.1    Steitz, J.A.2
  • 131
    • 77953928753 scopus 로고    scopus 로고
    • HITS-CLIP: panoramic views of protein-RNA regulation in living cells
    • Darnell R.B. HITS-CLIP: panoramic views of protein-RNA regulation in living cells. Wiley Interdiscip. Rev. RNA 2010, 1:266-286.
    • (2010) Wiley Interdiscip. Rev. RNA , vol.1 , pp. 266-286
    • Darnell, R.B.1
  • 132
    • 27944508215 scopus 로고    scopus 로고
    • CLIP: a method for identifying protein-RNA interaction sites in living cells
    • Ule J., et al. CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods 2005, 37:376-386.
    • (2005) Methods , vol.37 , pp. 376-386
    • Ule, J.1
  • 133
    • 67649840910 scopus 로고    scopus 로고
    • CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo
    • Wang Z., et al. CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo. Methods 2009, 48:287-293.
    • (2009) Methods , vol.48 , pp. 287-293
    • Wang, Z.1
  • 134
    • 0024274359 scopus 로고
    • Intra-RNA and RNA-protein cross-linking techniques in Escherichia coli ribosomes
    • Brimacombe R., et al. Intra-RNA and RNA-protein cross-linking techniques in Escherichia coli ribosomes. Methods Enzymol. 1988, 164:287-309.
    • (1988) Methods Enzymol. , vol.164 , pp. 287-309
    • Brimacombe, R.1
  • 135
    • 84894247159 scopus 로고    scopus 로고
    • RIPiT-Seq: a high-throughput approach for footprinting RNA:protein complexes
    • Singh G., et al. RIPiT-Seq: a high-throughput approach for footprinting RNA:protein complexes. Methods 2014, 65:320-332.
    • (2014) Methods , vol.65 , pp. 320-332
    • Singh, G.1


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