-
1
-
-
84864026311
-
BRCA mutation frequency and patterns of treatment response in BRCA mutationpositive women with ovarian cancer: A report from the Australian ovarian cancer study group
-
Alsop K, Fereday S, Meldrum C, deFazio A, Emmanuel C, George J, Dobrovic A, Birrer MJ, Webb PM, Stewart C et al. 2012 BRCA mutation frequency and patterns of treatment response in BRCA mutationpositive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. Journal of Clinical Oncology 30 2654-2663. (doi:10.1200/JCO.2011.39.8545)
-
(2012)
Journal of Clinical Oncology
, vol.30
, pp. 2654-2663
-
-
Alsop, K.1
Fereday, S.2
Meldrum, C.3
DeFazio, A.4
Emmanuel, C.5
George, J.6
Dobrovic, A.7
Birrer, M.J.8
Webb, P.M.9
Stewart, C.10
-
2
-
-
82255181181
-
Activity-based chemical proteomics accelerates inhibitor development for deubiqui-tylating enzymes
-
Altun M, Kramer HB, Willems LI, McDermott JL, Leach CA, Goldenberg SJ, Kumar KG, Konietzny R, Fischer R, Kogan E et al. 2011 Activity-based chemical proteomics accelerates inhibitor development for deubiqui-tylating enzymes. Chemistry & Biology 18 1401-1412. (doi:10.1016/j.chembiol.2011.08.018)
-
(2011)
Chemistry & Biology
, vol.18
, pp. 1401-1412
-
-
Altun, M.1
Kramer, H.B.2
Willems, L.I.3
McDermott, J.L.4
Leach, C.A.5
Goldenberg, S.J.6
Kumar, K.G.7
Konietzny, R.8
Fischer, R.9
Kogan, E.10
-
3
-
-
40849149557
-
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
-
Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S et al. 2008 Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. PNAS 105 3443-3448. (doi:10.1073/pnas.0712384105)
-
(2008)
PNAS
, vol.105
, pp. 3443-3448
-
-
Barber, T.D.1
McManus, K.2
Yuen, K.W.3
Reis, M.4
Parmigiani, G.5
Shen, D.6
Barrett, I.7
Nouhi, Y.8
Spencer, F.9
Markowitz, S.10
-
4
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I & Zhao K 2007 High-resolution profiling of histone methylations in the human genome. Cell 129 823-837. (doi:10.1016/j.cell.2007.05.009)
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
5
-
-
80455162312
-
Genome-wide function of H2B ubiquitylation in promoter and genic regions
-
Batta K, Zhang Z, Yen K, Goffman DB & Pugh BF 2011 Genome-wide function of H2B ubiquitylation in promoter and genic regions. Genes and Development 25 2254-2265. (doi:10.1101/gad.177238.111)
-
(2011)
Genes and Development
, vol.25
, pp. 2254-2265
-
-
Batta, K.1
Zhang, Z.2
Yen, K.3
Goffman, D.B.4
Pugh, B.F.5
-
6
-
-
38649108184
-
Unraveling epigenetic regulation in embryonic stem cells
-
Bibikova M, Laurent LC, Ren B, Loring JF & Fan JB 2008 Unraveling epigenetic regulation in embryonic stem cells. Cell Stem Cell 2 123-134. (doi:10.1016/j.stem.2008.01.005)
-
(2008)
Cell Stem Cell
, vol.2
, pp. 123-134
-
-
Bibikova, M.1
Laurent, L.C.2
Ren, B.3
Loring, J.F.4
Fan, J.B.5
-
7
-
-
84856691330
-
A tumor suppressor function of smurf2 associated with controlling chromatin landscape and genome stability through RNF20
-
Blank M, Tang Y, Yamashita M, Burkett SS, Cheng SY & Zhang YE 2012 A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20. Nature Medicine 18 227-234. (doi:10.1038/nm.2596)
-
(2012)
Nature Medicine
, vol.18
, pp. 227-234
-
-
Blank, M.1
Tang, Y.2
Yamashita, M.3
Burkett, S.S.4
Cheng, S.Y.5
Zhang, Y.E.6
-
8
-
-
0019523261
-
Guanosine-5'-phosphate synthetase and guanosine-5' -phosphate kinase in rat hepatomas and kidney tumors
-
Boritzki TJ, Jackson RC, Morris HP & Weber G 1981 Guanosine-5'-phosphate synthetase and guanosine-5' -phosphate kinase in rat hepatomas and kidney tumors. Biochimica et Biophysica Acta 658 102-110. (doi:10.1016/0005-2744(81)90253-9)
-
(1981)
Biochimica et Biophysica Acta
, vol.658
, pp. 102-110
-
-
Boritzki, T.J.1
Jackson, R.C.2
Morris, H.P.3
Weber, G.4
-
9
-
-
84863302006
-
Shaping the landscape: Mechanistic consequences of ubiquitin modification of chromatin
-
Braun S & Madhani HD 2012 Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin. EMBO Reports 13 619-630. (doi:10.1038/embor.2012.78)
-
(2012)
EMBO Reports
, vol.13
, pp. 619-630
-
-
Braun, S.1
Madhani, H.D.2
-
10
-
-
13344260610
-
Bre1 is required for notch signaling and histone modification
-
Bray S, Musisi H & Bienz M 2005 Bre1 is required for Notch signaling and histone modification. Developmental Cell 8 279-286. (doi:10.1016/j.devcel.2004.11.020)
-
(2005)
Developmental Cell
, vol.8
, pp. 279-286
-
-
Bray, S.1
Musisi, H.2
Bienz, M.3
-
11
-
-
0036682364
-
Gene silencing: Trans-histone regulatory pathway in chromatin
-
Briggs SD, Xiao T, Sun ZW, Caldwell JA, Shabanowitz J, Hunt DF, Allis CD & Strahl BD 2002 Gene silencing: trans-histone regulatory pathway in chromatin. Nature 418 498. (doi:10.1038/nature00970)
-
(2002)
Nature
, vol.418
, pp. 498
-
-
Briggs, S.D.1
Xiao, T.2
Sun, Z.W.3
Caldwell, J.A.4
Shabanowitz, J.5
Hunt, D.F.6
Allis, C.D.7
Strahl, B.D.8
-
12
-
-
84870945375
-
Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system
-
Buckley SM, Aranda-Orgilles B, Strikoudis A, Apostolou E, Loizou E, Moran-Crusio K, Farnsworth CL, Koller AA, Dasgupta R, Silva JC et al. 2012 Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system. Cell Stem Cell 11 783-798. (doi:10.1016/j.stem.2012.09.011)
-
(2012)
Cell Stem Cell
, vol.11
, pp. 783-798
-
-
Buckley, S.M.1
Aranda-Orgilles, B.2
Strikoudis, A.3
Apostolou, E.4
Loizou, E.5
Moran-Crusio, K.6
Farnsworth, C.L.7
Koller, A.A.8
Dasgupta, R.9
Silva, J.C.10
-
14
-
-
58149398016
-
Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny
-
Buszczak M, Paterno S & Spradling AC 2009 Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny. Science 323 248-251. (doi:10.1126/science.1165678)
-
(2009)
Science
, vol.323
, pp. 248-251
-
-
Buszczak, M.1
Paterno, S.2
Spradling, A.C.3
-
15
-
-
70349731733
-
Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability
-
Chandrasekharan MB, Huang F & Sun ZW 2009 Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability. PNAS 106 16686-16691. (doi:10.1073/pnas.0907862106)
-
(2009)
PNAS
, vol.106
, pp. 16686-16691
-
-
Chandrasekharan, M.B.1
Huang, F.2
Sun, Z.W.3
-
16
-
-
84866021069
-
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
-
Chauhan D, Tian Z, Nicholson B, Kumar KG, Zhou B, Carrasco R, McDermott JL, Leach CA, Fulcinniti M, Kodrasov MP et al. 2012 A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell 22 345-358. (doi:10.1016/j.ccr.2012.08.007)
-
(2012)
Cancer Cell
, vol.22
, pp. 345-358
-
-
Chauhan, D.1
Tian, Z.2
Nicholson, B.3
Kumar, K.G.4
Zhou, B.5
Carrasco, R.6
McDermott, J.L.7
Leach, C.A.8
Fulcinniti, M.9
Kodrasov, M.P.10
-
17
-
-
84865765333
-
Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation
-
Chen S, Li J, Wang DL & Sun FL 2012 Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation. Cell Research 22 1402-1405. (doi:10.1038/cr.2012.114)
-
(2012)
Cell Research
, vol.22
, pp. 1402-1405
-
-
Chen, S.1
Li, J.2
Wang, D.L.3
Sun, F.L.4
-
18
-
-
84860187274
-
Deficiency in mammalian histone H2B ubiquitin ligase bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
-
Chernikova SB, Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM et al. 2012 Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability. Cancer Research 72 2111-2119. (doi:10.1158/0008-5472.CAN-11-2209)
-
(2012)
Cancer Research
, vol.72
, pp. 2111-2119
-
-
Chernikova, S.B.1
Razorenova, O.V.2
Higgins, J.P.3
Sishc, B.J.4
Nicolau, M.5
Dorth, J.A.6
Chernikova, D.A.7
Kwok, S.8
Brooks, J.D.9
Bailey, S.M.10
-
19
-
-
67650731222
-
Deciphering histone 2A deubiquitination
-
Clague MJ, Coulson JM & Urbe S 2008 Deciphering histone 2A deubiquitination. Genome Biology 9 202. (doi:10.1186/gb-2008-9-1-202)
-
(2008)
Genome Biology
, vol.9
, pp. 202
-
-
Clague, M.J.1
Coulson, J.M.2
Urbe, S.3
-
20
-
-
84880931087
-
Deubiquitylases from genes to organism
-
Clague MJ, Barsukov I, Coulson JM, Liu H, Rigden DJ & Urbe S 2013 Deubiquitylases from genes to organism. Physiological Reviews 93 1289-1315. (doi:10.1152/physrev.00002.2013)
-
(2013)
Physiological Reviews
, vol.93
, pp. 1289-1315
-
-
Clague, M.J.1
Barsukov, I.2
Coulson, J.M.3
Liu, H.4
Rigden, D.J.5
Urbe, S.6
-
21
-
-
76449094879
-
The therapeutic potential of deubiquitinating enzyme inhibitors
-
Colland F 2010 The therapeutic potential of deubiquitinating enzyme inhibitors. Biochemical Society Transactions 38 137-143. (doi:10.1042/BST0380137)
-
(2010)
Biochemical Society Transactions
, vol.38
, pp. 137-143
-
-
Colland, F.1
-
22
-
-
68849126660
-
Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
-
Colland F, Formstecher E, Jacq X, Reverdy C, Planquette C, Conrath S, Trouplin V, Bianchi J, Aushev VN, Camonis J et al. 2009 Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells. Molecular Cancer Therapeutics 8 2286-2295. (doi:10.1158/1535-7163.MCT-09-0097)
-
(2009)
Molecular Cancer Therapeutics
, vol.8
, pp. 2286-2295
-
-
Colland, F.1
Formstecher, E.2
Jacq, X.3
Reverdy, C.4
Planquette, C.5
Conrath, S.6
Trouplin, V.7
Bianchi, J.8
Aushev, V.N.9
Camonis, J.10
-
23
-
-
1842431904
-
Tumour suppression: Disruption of HAUSP gene stabilizes p53
-
following 486
-
Cummins JM, Rago C, Kohli M, Kinzler KW, Lengauer C & Vogelstein B 2004 Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature 428 1 p following 486. (doi:10.1038/nature02501)
-
(2004)
Nature
, vol.428
-
-
Cummins, J.M.1
Rago, C.2
Kohli, M.3
Kinzler, K.W.4
Lengauer, C.5
Vogelstein, B.6
-
25
-
-
54349116510
-
Histone H2B ubiquitination: The cancer connection
-
Espinosa JM 2008 Histone H2B ubiquitination: the cancer connection. Genes and Development 22 2743-2749. (doi:10.1101/gad.1732108)
-
(2008)
Genes and Development
, vol.22
, pp. 2743-2749
-
-
Espinosa, J.M.1
-
26
-
-
0031878851
-
The disruption of ND10 during herpes simplex virus infection correlates with the vmw110- and proteasome-dependent loss of several PML isoforms
-
Everett RD, Freemont P, Saitoh H, Dasso M, Orr A, Kathoria M & Parkinson J 1998 The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms. Journal of Virology 72 6581-6591.
-
(1998)
Journal of Virology
, vol.72
, pp. 6581-6591
-
-
Everett, R.D.1
Freemont, P.2
Saitoh, H.3
Dasso, M.4
Orr, A.5
Kathoria, M.6
Parkinson, J.7
-
28
-
-
78751515133
-
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
-
Fierz B, Chatterjee C, McGinty RK, Bar-Dagan M, Raleigh DP & Muir TW 2011 Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction. Nature Chemical Biology 7 113-119. (doi:10.1038/nchembio.501)
-
(2011)
Nature Chemical Biology
, vol.7
, pp. 113-119
-
-
Fierz, B.1
Chatterjee, C.2
McGinty, R.K.3
Bar-Dagan, M.4
Raleigh, D.P.5
Muir, T.W.6
-
29
-
-
84870708220
-
Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis
-
Fierz B, Kilic S, Hieb AR, Luger K & Muir TW 2012 Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis. Journal of the American Chemical Society 134 19548-19551. (doi:10.1021/ja308908p)
-
(2012)
Journal of the American Chemical Society
, vol.134
, pp. 19548-19551
-
-
Fierz, B.1
Kilic, S.2
Hieb, A.R.3
Luger, K.4
Muir, T.W.5
-
30
-
-
46149091721
-
H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation
-
Fleming AB, Kao CF, Hillyer C, Pikaart M & Osley MA 2008 H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation. Molecular Cell 31 57-66. (doi:10.1016/j.molcel.2008.04.025)
-
(2008)
Molecular Cell
, vol.31
, pp. 57-66
-
-
Fleming, A.B.1
Kao, C.F.2
Hillyer, C.3
Pikaart, M.4
Osley, M.A.5
-
31
-
-
84904036680
-
Writing and reading H2B monoubiquitylation
-
Fuchs G & Oren M 2014 Writing and reading H2B monoubiquitylation. Biochimica et Biophysica Acta 1839 694-701. (doi:10.1016/j.bbagrm.2014.01.002)
-
(2014)
Biochimica et Biophysica Acta
, vol.1839
, pp. 694-701
-
-
Fuchs, G.1
Oren, M.2
-
32
-
-
84861968321
-
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
-
Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M et al. 2012 RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Molecular Cell 46 662-673. (doi:10.1016/j.molcel.2012.05.023)
-
(2012)
Molecular Cell
, vol.46
, pp. 662-673
-
-
Fuchs, G.1
Shema, E.2
Vesterman, R.3
Kotler, E.4
Wolchinsky, Z.5
Wilder, S.6
Golomb, L.7
Pribluda, A.8
Zhang, F.9
Haj-Yahya, M.10
-
33
-
-
79957574184
-
An acetylation-mono-ubiquitination switch on lysine 120 of H2B
-
Gatta R, Dolfini D, Zambelli F, Imbriano C, Pavesi G & Mantovani R 2011 An acetylation-mono-ubiquitination switch on lysine 120 of H2B. Epigenetics 6 630-637. (doi:10.4161/epi.6.5.15623)
-
(2011)
Epigenetics
, vol.6
, pp. 630-637
-
-
Gatta, R.1
Dolfini, D.2
Zambelli, F.3
Imbriano, C.4
Pavesi, G.5
Mantovani, R.6
-
34
-
-
20444457518
-
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
-
Glinsky GV, Berezovska O & Glinskii AB 2005 Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. Journal of Clinical Investigation 115 1503-1521. (doi:10.1172/JCI23412)
-
(2005)
Journal of Clinical Investigation
, vol.115
, pp. 1503-1521
-
-
Glinsky, G.V.1
Berezovska, O.2
Glinskii, A.B.3
-
35
-
-
84856107676
-
The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination
-
Hahn MA, Dickson KA, Jackson S, Clarkson A, Gill AJ & Marsh DJ 2012 The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. Human Molecular Genetics 21 559-568. (doi:10.1093/hmg/ddr490)
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 559-568
-
-
Hahn, M.A.1
Dickson, K.A.2
Jackson, S.3
Clarkson, A.4
Gill, A.J.5
Marsh, D.J.6
-
36
-
-
0035805582
-
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
-
Hashizume R, Fukuda M, Maeda I, Nishikawa H, Oyake D, Yabuki Y, Ogata H & Ohta T 2001 The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. Journal of Biological Chemistry 276 14537-14540. (doi:10.1074/jbc.C000881200)
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Nishikawa, H.4
Oyake, D.5
Yabuki, Y.6
Ogata, H.7
Ohta, T.8
-
37
-
-
0242361623
-
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated ubp8
-
Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA & Berger SL 2003 Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes and Development 17 2648-2663. (doi:10.1101/gad.1144003)
-
(2003)
Genes and Development
, vol.17
, pp. 2648-2663
-
-
Henry, K.W.1
Wyce, A.2
Lo, W.S.3
Duggan, L.J.4
Emre, N.C.5
Kao, C.F.6
Pillus, L.7
Shilatifard, A.8
Osley, M.A.9
Berger, S.L.10
-
38
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y, Zgheib O, Ditullio RA Jr, Gorgoulis VG, Zacharatos P, Petty TJ, Sheston EA, Mellert HS, Stavridi ES & Halazonetis TD 2004 Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432 406-411. (doi:10.1038/nature03114)
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio, R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
39
-
-
0037248593
-
A conserved RING finger protein required for histone H2B monoubiquitination and cell size control
-
Hwang WW, Venkatasubrahmanyam S, Ianculescu AG, Tong A, Boone C & Madhani HD 2003 A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Molecular Cell 11 261-266. (doi:10.1016/S1097-2765(02)00826-2)
-
(2003)
Molecular Cell
, vol.11
, pp. 261-266
-
-
Hwang, W.W.1
Venkatasubrahmanyam, S.2
Ianculescu, A.G.3
Tong, A.4
Boone, C.5
Madhani, H.D.6
-
40
-
-
79954993409
-
Chatting histone modifications in mammals
-
Izzo A & Schneider R 2010 Chatting histone modifications in mammals. Briefings in Functional Genomics 9 429-443. (doi:10.1093/bfgp/elq024)
-
(2010)
Briefings in Functional Genomics
, vol.9
, pp. 429-443
-
-
Izzo, A.1
Schneider, R.2
-
41
-
-
0034308251
-
The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
-
Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK & Reimann JD 2000 The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends in Cell Biology 10 429-439. (doi:10.1016/S0962-8924(00)01834-1)
-
(2000)
Trends in Cell Biology
, vol.10
, pp. 429-439
-
-
Jackson, P.K.1
Eldridge, A.G.2
Freed, E.3
Furstenthal, L.4
Hsu, J.Y.5
Kaiser, B.K.6
Reimann, J.D.7
-
43
-
-
77953277032
-
The paf1 complex: Platform or player in RNA polymerase II transcription?
-
Jaehning JA 2010 The Paf1 complex: platform or player in RNA polymerase II transcription? Biochimica et Biophysica Acta 1799 379-388. (doi:10.1016/j.bbagrm.2010.01.001)
-
(2010)
Biochimica et Biophysica Acta
, vol.1799
, pp. 379-388
-
-
Jaehning, J.A.1
-
44
-
-
0035805498
-
Magnesium-dependent association and folding of oligonucleosomes reconstituted with ubiquitinated H2A
-
Jason LJ, Moore SC, Ausio J & Lindsey G 2001 Magnesium-dependent association and folding of oligonucleosomes reconstituted with ubiquitinated H2A. Journal of Biological Chemistry 276 14597-14601. (doi:10.1074/jbc.M011153200)
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 14597-14601
-
-
Jason, L.J.1
Moore, S.C.2
Ausio, J.3
Lindsey, G.4
-
45
-
-
84861594601
-
The enigmatic role of H2Bub1 in cancer
-
Johnsen SA 2012 The enigmatic role of H2Bub1 in cancer. FEBS Letters 586 1592-1601. (doi:10.1016/j.febslet.2012.04.002)
-
(2012)
FEBS Letters
, vol.586
, pp. 1592-1601
-
-
Johnsen, S.A.1
-
46
-
-
79953185042
-
Regulation of histone H2A and H2B deubiquitination and xenopus development by USP12 and USP46
-
Joo HY, Jones A, Yang C, Zhai L, Smith AD IV, Zhang Z, Chandrasekharan MB, Sun ZW, Renfrow MB, Wang Y et al. 2011 Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46. Journal of Biological Chemistry 286 7190-7201. (doi:10.1074/jbc.M110.158311)
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 7190-7201
-
-
Joo, H.Y.1
Jones, A.2
Yang, C.3
Zhai, L.4
Smith, A.D.5
Zhang, Z.6
Chandrasekharan, M.B.7
Sun, Z.W.8
Renfrow, M.B.9
Wang, Y.10
-
47
-
-
84861843882
-
H2B monoubiquitylation is a 5'-enriched active transcription mark and correlates with exon-intron structure in human cells
-
Jung I, Kim SK, Kim M, Han YM, Kim YS, Kim D & Lee D 2012 H2B monoubiquitylation is a 5'-enriched active transcription mark and correlates with exon-intron structure in human cells. Genome Research 22 1026-1035. (doi:10.1101/gr.120634.111)
-
(2012)
Genome Research
, vol.22
, pp. 1026-1035
-
-
Jung, I.1
Kim, S.K.2
Kim, M.3
Han, Y.M.4
Kim, Y.S.5
Kim, D.6
Lee, D.7
-
48
-
-
80055102133
-
The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair
-
Kari V, Shchebet A, Neumann H & Johnsen SA 2011 The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair. Cell Cycle 10 3495-3504. (doi:10.4161/cc.10.20.17769)
-
(2011)
Cell Cycle
, vol.10
, pp. 3495-3504
-
-
Kari, V.1
Shchebet, A.2
Neumann, H.3
Johnsen, S.A.4
-
49
-
-
84861994785
-
The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells
-
Karpiuk O, Najafova Z, Kramer F, Hennion M, Galonska C, Konig A, Snaidero N, Vogel T, Shchebet A, Begus-Nahrmann Y et al. 2012 The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Molecular Cell 46 705-713. (doi:10.1016/j.molcel.2012.05.022)
-
(2012)
Molecular Cell
, vol.46
, pp. 705-713
-
-
Karpiuk, O.1
Najafova, Z.2
Kramer, F.3
Hennion, M.4
Galonska, C.5
Konig, A.6
Snaidero, N.7
Vogel, T.8
Shchebet, A.9
Begus-Nahrmann, Y.10
-
50
-
-
77951247308
-
WDR20 regulates activity of the USP12 ! UAF1 deubiquitinating enzyme complex
-
Kee Y, Yang K, Cohn MA, Haas W, Gygi SP & D'Andrea AD 2010 WDR20 regulates activity of the USP12 ! UAF1 deubiquitinating enzyme complex. Journal of Biological Chemistry 285 11252-11257. (doi:10.1074/jbc.M109.095141)
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 11252-11257
-
-
Kee, Y.1
Yang, K.2
Cohn, M.A.3
Haas, W.4
Gygi, S.P.5
D'Andrea, A.D.6
-
51
-
-
28444463638
-
The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions
-
Kim J, Hake SB & Roeder RG 2005 The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Molecular Cell 20 759-770. (doi:10.1016/j.molcel.2005.11.012)
-
(2005)
Molecular Cell
, vol.20
, pp. 759-770
-
-
Kim, J.1
Hake, S.B.2
Roeder, R.G.3
-
52
-
-
65249105512
-
RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW & Roeder RG 2009 RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137 459-471. (doi:10.1016/j.cell.2009.02.027)
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
Guermah, M.2
McGinty, R.K.3
Lee, J.S.4
Tang, Z.5
Milne, T.A.6
Shilatifard, A.7
Muir, T.W.8
Roeder, R.G.9
-
53
-
-
84897995587
-
The histone methyltransferase dot1/DOT1L as a critical regulator of the cell cycle
-
Kim W, Choi M & Kim JE 2014 The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle. Cell Cycle 13 726-738. (doi:10.4161/cc.28104)
-
(2014)
Cell Cycle
, vol.13
, pp. 726-738
-
-
Kim, W.1
Choi, M.2
Kim, J.E.3
-
54
-
-
14644406268
-
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7
-
van der Knaap JA, Kumar BR, Moshkin YM, Langenberg K, Krijgsveld J, Heck AJ, Karch F & Verrijzer CP 2005 GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Molecular Cell 17 695-707. (doi:10.1016/j.molcel.2005.02.013)
-
(2005)
Molecular Cell
, vol.17
, pp. 695-707
-
-
Van Der Knaap, J.A.1
Kumar, B.R.2
Moshkin, Y.M.3
Langenberg, K.4
Krijgsveld, J.5
Heck, A.J.6
Karch, F.7
Verrijzer, C.P.8
-
55
-
-
75149157727
-
Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes
-
van der Knaap JA, Kozhevnikova E, Langenberg K, Moshkin YM & Verrijzer CP 2010 Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes. Molecular and Cellular Biology 30 736-744. (doi:10.1128/MCB.01121-09)
-
(2010)
Molecular and Cellular Biology
, vol.30
, pp. 736-744
-
-
Van Der Knaap, J.A.1
Kozhevnikova, E.2
Langenberg, K.3
Moshkin, Y.M.4
Verrijzer, C.P.5
-
56
-
-
84888409855
-
The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination
-
Kogure M, Takawa M, Saloura V, Sone K, Piao L, Ueda K, Ibrahim R, Tsunoda T, Sugiyama M, Atomi Y et al. 2013 The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination. Neoplasia 15 1251-1261.
-
(2013)
Neoplasia
, vol.15
, pp. 1251-1261
-
-
Kogure, M.1
Takawa, M.2
Saloura, V.3
Sone, K.4
Piao, L.5
Ueda, K.6
Ibrahim, R.7
Tsunoda, T.8
Sugiyama, M.9
Atomi, Y.10
-
57
-
-
13444292904
-
Histone modifications defining active genes persist after transcriptional and mitotic inactivation
-
Kouskouti A & Talianidis I 2005 Histone modifications defining active genes persist after transcriptional and mitotic inactivation. EMBO Journal 24 347-357. (doi:10.1038/sj.emboj.7600516)
-
(2005)
EMBO Journal
, vol.24
, pp. 347-357
-
-
Kouskouti, A.1
Talianidis, I.2
-
58
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T 2007 Chromatin modifications and their function. Cell 128 693-705. (doi:10.1016/j.cell.2007.02.005)
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
59
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J & Gu W 2002 Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416 648-653. (doi:10.1038/nature737)
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
Gu, W.7
-
60
-
-
1842421376
-
A dynamic role of HAUSP in the p53-mdm2 pathway
-
Li M, Brooks CL, Kon N & Gu W 2004 A dynamic role of HAUSP in the p53-Mdm2 pathway. Molecular Cell 13 879-886. (doi:10.1016/S1097-2765(04)00157-1)
-
(2004)
Molecular Cell
, vol.13
, pp. 879-886
-
-
Li, M.1
Brooks, C.L.2
Kon, N.3
Gu, W.4
-
61
-
-
45849134528
-
Differential display identifies overexpression of the USP36 gene, encoding a deubiquitinating enzyme, in ovarian cancer
-
Li J, Olson LM, Zhang Z, Li L, Bidder M, Nguyen L, Pfeifer J & Rader JS 2008 Differential display identifies overexpression of the USP36 gene, encoding a deubiquitinating enzyme, in ovarian cancer. International Journal of Medical Sciences 5 133-142. (doi:10.7150/ijms.5.133)
-
(2008)
International Journal of Medical Sciences
, vol.5
, pp. 133-142
-
-
Li, J.1
Olson, L.M.2
Zhang, Z.3
Li, L.4
Bidder, M.5
Nguyen, L.6
Pfeifer, J.7
Rader, J.S.8
-
62
-
-
77949384048
-
Mammalian SWI/SNF - A subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B
-
Li XS, Trojer P, Matsumura T, Treisman JE & Tanese N 2010 Mammalian SWI/SNF - a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. Molecular and Cellular Biology 30 1673-1688. (doi:10.1128/MCB.00540-09)
-
(2010)
Molecular and Cellular Biology
, vol.30
, pp. 1673-1688
-
-
Li, X.S.1
Trojer, P.2
Matsumura, T.3
Treisman, J.E.4
Tanese, N.5
-
63
-
-
84864344881
-
USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma
-
Li J, Wang Z & Li Y 2012 USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma. Journal of Cancer Research and Clinical Oncology 138 1291-1297. (doi:10.1007/s00432-012-1191-5)
-
(2012)
Journal of Cancer Research and Clinical Oncology
, vol.138
, pp. 1291-1297
-
-
Li, J.1
Wang, Z.2
Li, Y.3
-
64
-
-
84861461517
-
USP22 antagonizes p53 transcriptional activation by deubiquitinating sirt1 to suppress cell apoptosis and is required for mouse embryonic development
-
Lin Z, Yang H, Kong Q, Li J, Lee SM, Gao B, Dong H, Wei J, Song J, Zhang DD et al. 2012 USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development. Molecular Cell 46 484-494. (doi:10.1016/j.molcel.2012.03.024)
-
(2012)
Molecular Cell
, vol.46
, pp. 484-494
-
-
Lin, Z.1
Yang, H.2
Kong, Q.3
Li, J.4
Lee, S.M.5
Gao, B.6
Dong, H.7
Wei, J.8
Song, J.9
Zhang, D.D.10
-
65
-
-
84872918926
-
Knock-down of USP22 by small interfering RNA interference inhibits HepG2 cell proliferation and induces cell cycle arrest
-
Ling SB, Sun DG, Tang B, Guo C, Zhang Y, Liang R & Wang LM 2012 Knock-down of USP22 by small interfering RNA interference inhibits HepG2 cell proliferation and induces cell cycle arrest. Cellular and Molecular Biology 58 (Suppl) OL1803-OL1808.
-
(2012)
Cellular and Molecular Biology
, vol.58
, pp. OL1803-OL1808
-
-
Ling, S.B.1
Sun, D.G.2
Tang, B.3
Guo, C.4
Zhang, Y.5
Liang, R.6
Wang, L.M.7
-
66
-
-
80052069445
-
RINGs of good and evil: Ring finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
-
Lipkowitz S & Weissman AM 2011 RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis. Nature Reviews. Cancer 11 629-643. (doi:10.1038/nrc3120)
-
(2011)
Nature Reviews. Cancer
, vol.11
, pp. 629-643
-
-
Lipkowitz, S.1
Weissman, A.M.2
-
67
-
-
64049118773
-
Human BRE1 is an E3 ubiquitin ligase for ebp1 tumor suppressor
-
Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J, Brat DJ, Sun SY, Zhou W, Gu W et al. 2009 Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Molecular Biology of the Cell 20 757-768. (doi:10.1091/mbc.E08-09-0983)
-
(2009)
Molecular Biology of the Cell
, vol.20
, pp. 757-768
-
-
Liu, Z.1
Oh, S.M.2
Okada, M.3
Liu, X.4
Cheng, D.5
Peng, J.6
Brat, D.J.7
Sun, S.Y.8
Zhou, W.9
Gu, W.10
-
68
-
-
79952030196
-
Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer
-
Liu YL, Yang YM, Xu H & Dong XS 2011 Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer. Journal of Surgical Oncology 103 283-289. (doi:10.1002/jso.21802)
-
(2011)
Journal of Surgical Oncology
, vol.103
, pp. 283-289
-
-
Liu, Y.L.1
Yang, Y.M.2
Xu, H.3
Dong, X.S.4
-
69
-
-
84897373749
-
The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination
-
Long L, Thelen JP, Furgason M, Haj-Yahya M, Brik A, Cheng D, Peng J & Yao T 2014 The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination. Journal of Biological Chemistry 289 8916-8930. (doi:10.1074/jbc.M114.551754)
-
(2014)
Journal of Biological Chemistry
, vol.289
, pp. 8916-8930
-
-
Long, L.1
Thelen, J.P.2
Furgason, M.3
Haj-Yahya, M.4
Brik, A.5
Cheng, D.6
Peng, J.7
Yao, T.8
-
70
-
-
78751616954
-
Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells
-
Lv L, Xiao XY, Gu ZH, Zeng FQ, Huang LQ & Jiang GS 2011 Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells. Molecular and Cellular Biochemistry 346 11-21. (doi:10.1007/s11010-010-0585-4)
-
(2011)
Molecular and Cellular Biochemistry
, vol.346
, pp. 11-21
-
-
Lv, L.1
Xiao, X.Y.2
Gu, Z.H.3
Zeng, F.Q.4
Huang, L.Q.5
Jiang, G.S.6
-
71
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery DL, Vandenberg CJ & Hiom K 2002 Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO Journal 21 6755-6762. (doi:10.1093/emboj/cdf691)
-
(2002)
EMBO Journal
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
72
-
-
44849100496
-
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
-
McGinty RK, Kim J, Chatterjee C, Roeder RG & Muir TW 2008 Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation. Nature 453 812-816. (doi:10.1038/nature06906)
-
(2008)
Nature
, vol.453
, pp. 812-816
-
-
McGinty, R.K.1
Kim, J.2
Chatterjee, C.3
Roeder, R.G.4
Muir, T.W.5
-
73
-
-
0344837759
-
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
-
Min J, Feng Q, Li Z, Zhang Y & Xu RM 2003 Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. Cell 112 711-723. (doi:10.1016/S0092-8674(03)00114-4)
-
(2003)
Cell
, vol.112
, pp. 711-723
-
-
Min, J.1
Feng, Q.2
Li, Z.3
Zhang, Y.4
Xu, R.M.5
-
74
-
-
8844232663
-
The RING domain of mdm2 mediates histone ubiquitylation and transcriptional repression
-
Minsky N & Oren M 2004 The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression. Molecular Cell 16 631-639. (doi:10.1016/j.molcel.2004.10.016)
-
(2004)
Molecular Cell
, vol.16
, pp. 631-639
-
-
Minsky, N.1
Oren, M.2
-
75
-
-
43149122898
-
Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells
-
Minsky N, Shema E, Field Y, Schuster M, Segal E & Oren M 2008 Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nature Cell Biology 10 483-488. (doi:10.1038/ncb1712)
-
(2008)
Nature Cell Biology
, vol.10
, pp. 483-488
-
-
Minsky, N.1
Shema, E.2
Field, Y.3
Schuster, M.4
Segal, E.5
Oren, M.6
-
76
-
-
84865455417
-
The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation
-
Moretti J, Chastagner P, Liang CC, Cohn MA, Israel A & Brou C 2012 The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation. Journal of Biological Chemistry 287 29429-29441. (doi:10.1074/jbc.M112.366807)
-
(2012)
Journal of Biological Chemistry
, vol.287
, pp. 29429-29441
-
-
Moretti, J.1
Chastagner, P.2
Liang, C.C.3
Cohn, M.A.4
Israel, A.5
Brou, C.6
-
77
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E et al. 2011 Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Molecular Cell 41 529-542. (doi:10.1016/j.molcel.2011.02.015)
-
(2011)
Molecular Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
Lerenthal, Y.2
Gana-Weisz, M.3
Mass, G.4
So, S.5
Wang, S.Y.6
Eppink, B.7
Chung, Y.M.8
Shalev, G.9
Shema, E.10
-
78
-
-
0021812747
-
Identification of ubiquitinated histones 2A and 2B in physarum polycephalum
-
Mueller RD, Yasuda H, Hatch CL, Bonner WM & Bradbury EM 1985 Identification of ubiquitinated histones 2A and 2B in Physarum polycephalum. Disappearance of these proteins at metaphase and reappearance at anaphase. Journal of Biological Chemistry 260 5147-5153.
-
(1985)
Disappearance of These Proteins at Metaphase and Reappearance at Anaphase. Journal of Biological Chemistry
, vol.260
, pp. 5147-5153
-
-
Mueller, R.D.1
Yasuda, H.2
Hatch, C.L.3
Bonner, W.M.4
Bradbury, E.M.5
-
79
-
-
84896098750
-
Mutant p53 in cancer: New functions and therapeutic opportunities
-
Muller PA & Vousden KH 2014 Mutant p53 in cancer: new functions and therapeutic opportunities. Cancer Cell 25 304-317. (doi:10.1016/j.ccr.2014.01.021)
-
(2014)
Cancer Cell
, vol.25
, pp. 304-317
-
-
Muller, P.A.1
Vousden, K.H.2
-
80
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, Oliveira DV, Shimada M, Tauchi H, Suzuki H, Tashiro S et al. 2011 Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Molecular Cell 41 515-528. (doi:10.1016/j.molcel.2011.02.002)
-
(2011)
Molecular Cell
, vol.41
, pp. 515-528
-
-
Nakamura, K.1
Kato, A.2
Kobayashi, J.3
Yanagihara, H.4
Sakamoto, S.5
Oliveira, D.V.6
Shimada, M.7
Tauchi, H.8
Suzuki, H.9
Tashiro, S.10
-
81
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Network CGA 2011 Integrated genomic analyses of ovarian carcinoma. Nature 474 609-615. (doi:10.1038/nature10166)
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
Network CGA1
-
82
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Network CGA 2012 Comprehensive molecular portraits of human breast tumours. Nature 490 61-70. (doi:10.1038/nature11412)
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Network CGA1
-
83
-
-
0037144393
-
Ubiquitination of histone H2B by rad6 is required for efficient dot1-mediated methylation of histone H3 lysine 79
-
Ng HH, Xu RM, Zhang Y & Struhl K 2002 Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79. Journal of Biological Chemistry 277 34655-34657. (doi:10.1074/jbc.C200433200)
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 34655-34657
-
-
Ng, H.H.1
Xu, R.M.2
Zhang, Y.3
Struhl, K.4
-
84
-
-
36049036216
-
Human USP3 is a chromatin modifier required for S phase progression and genome stability
-
Nicassio F, Corrado N, Vissers JH, Areces LB, Bergink S, Marteijn JA, Geverts B, Houtsmuller AB, Vermeulen W, Di Fiore PP et al. 2007 Human USP3 is a chromatin modifier required for S phase progression and genome stability. Current Biology 17 1972-1977. (doi:10.1016/j.cub.2007.10.034)
-
(2007)
Current Biology
, vol.17
, pp. 1972-1977
-
-
Nicassio, F.1
Corrado, N.2
Vissers, J.H.3
Areces, L.B.4
Bergink, S.5
Marteijn, J.A.6
Geverts, B.7
Houtsmuller, A.B.8
Vermeulen, W.9
Di Fiore, P.P.10
-
85
-
-
79955938866
-
The multifaceted roles of USP7: New therapeutic opportunities
-
Nicholson B & Suresh Kumar KG 2011 The multifaceted roles of USP7: new therapeutic opportunities. Cell Biochemistry and Biophysics 60 61-68. (doi:10.1007/s12013-011-9185-5)
-
(2011)
Cell Biochemistry and Biophysics
, vol.60
, pp. 61-68
-
-
Nicholson, B.1
Suresh Kumar, K.G.2
-
86
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK & Bernards R 2005 A genomic and functional inventory of deubiquitinating enzymes. Cell 123 773-786. (doi:10.1016/j.cell.2005.11.007)
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
Bernards, R.7
-
87
-
-
84880632246
-
Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer
-
Ning J, Zhang J, Liu W, Lang Y, Xue Y & Xu S 2012 Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer. European Journal of Histochemistry 56 e46. (doi:10.4081/ejh.2012.e46)
-
(2012)
European Journal of Histochemistry
, vol.56
, pp. e46
-
-
Ning, J.1
Zhang, J.2
Liu, W.3
Lang, Y.4
Xue, Y.5
Xu, S.6
-
88
-
-
79958252915
-
Chromatin connections to pluripotency and cellular reprogramming
-
Orkin SH & Hochedlinger K 2011 Chromatin connections to pluripotency and cellular reprogramming. Cell 145 835-850. (doi:10.1016/j.cell.2011.05.019)
-
(2011)
Cell
, vol.145
, pp. 835-850
-
-
Orkin, S.H.1
Hochedlinger, K.2
-
90
-
-
33646691283
-
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
-
Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A & Reinberg D 2006 Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 125 703-717. (doi:10.1016/j.cell.2006.04.029)
-
(2006)
Cell
, vol.125
, pp. 703-717
-
-
Pavri, R.1
Zhu, B.2
Li, G.3
Trojer, P.4
Mandal, S.5
Shilatifard, A.6
Reinberg, D.7
-
91
-
-
84864535704
-
USP22 is useful as a novel molecular marker for predicting disease progression and patient prognosis of oral squamous cell carcinoma
-
Piao S, Liu Y, Hu J, Guo F, Ma J, Sun Y & Zhang B 2012 USP22 is useful as a novel molecular marker for predicting disease progression and patient prognosis of oral squamous cell carcinoma. PLoS ONE 7 e42540. (doi:10.1371/journal.pone.0042540)
-
(2012)
PLoS ONE
, vol.7
-
-
Piao, S.1
Liu, Y.2
Hu, J.3
Guo, F.4
Ma, J.5
Sun, Y.6
Zhang, B.7
-
92
-
-
84880074284
-
Increased expression of USP22 is associated with disease progression and patient prognosis of salivary duct carcinoma
-
Piao S, Ma J, Wang W, Liu Y, Zhang M, Chen H, Guo F, Zhang B & Guo F 2013 Increased expression of USP22 is associated with disease progression and patient prognosis of salivary duct carcinoma. Oral Oncology 49 796-801. (doi:10.1016/j.oraloncology.2013.03.454)
-
(2013)
Oral Oncology
, vol.49
, pp. 796-801
-
-
Piao, S.1
Ma, J.2
Wang, W.3
Liu, Y.4
Zhang, M.5
Chen, H.6
Guo, F.7
Zhang, B.8
Guo, F.9
-
93
-
-
68249128223
-
CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing
-
Pirngruber J, Shchebet A, Schreiber L, Shema E, Minsky N, Chapman RD, Eick D, Aylon Y, Oren M & Johnsen SA 2009 CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing. EMBO Reports 10 894-900. (doi:10.1038/embor.2009.108)
-
(2009)
EMBO Reports
, vol.10
, pp. 894-900
-
-
Pirngruber, J.1
Shchebet, A.2
Schreiber, L.3
Shema, E.4
Minsky, N.5
Chapman, R.D.6
Eick, D.7
Aylon, Y.8
Oren, M.9
Johnsen, S.A.10
-
94
-
-
80052248649
-
Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B
-
Prenzel T, Begus-Nahrmann Y, Kramer F, Hennion M, Hsu C, Gorsler T, Hintermair C, Eick D, Kremmer E, Simons M et al. 2011 Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B. Cancer Research 71 5739-5753. (doi:10.1158/0008-5472.CAN-11-1896)
-
(2011)
Cancer Research
, vol.71
, pp. 5739-5753
-
-
Prenzel, T.1
Begus-Nahrmann, Y.2
Kramer, F.3
Hennion, M.4
Hsu, C.5
Gorsler, T.6
Hintermair, C.7
Eick, D.8
Kremmer, E.9
Simons, M.10
-
95
-
-
84860112066
-
Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme
-
Reverdy C, Conrath S, Lopez R, Planquette C, Atmanene C, Collura V, Harpon J, Battaglia V, Vivat V, Sippl W et al. 2012 Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chemistry & Biology 19 467-477. (doi:10.1016/j.chembiol.2012.02.007)
-
(2012)
Chemistry & Biology
, vol.19
, pp. 467-477
-
-
Reverdy, C.1
Conrath, S.2
Lopez, R.3
Planquette, C.4
Atmanene, C.5
Collura, V.6
Harpon, J.7
Battaglia, V.8
Vivat, V.9
Sippl, W.10
-
96
-
-
11844269891
-
The parafibromin tumor suppressor protein is part of a human paf1 complex
-
Rozenblatt-Rosen O, Hughes CM, Nannepaga SJ, Shanmugam KS, Copeland TD, Guszczynski T, Resau JH & Meyerson M 2005 The parafibromin tumor suppressor protein is part of a human Paf1 complex. Molecular and Cellular Biology 25 612-620. (doi:10.1128/MCB. 25.2.612-620.2005)
-
(2005)
Molecular and Cellular Biology
, vol.25
, pp. 612-620
-
-
Rozenblatt-Rosen, O.1
Hughes, C.M.2
Nannepaga, S.J.3
Shanmugam, K.S.4
Copeland, T.D.5
Guszczynski, T.6
Resau, J.H.7
Meyerson, M.8
-
97
-
-
84895879913
-
Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity
-
Sadeghi L, Siggens L, Svensson JP & Ekwall K 2014 Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity. Nature Structural & Molecular Biology 21 236-243. (doi:10.1038/nsmb.2776)
-
(2014)
Nature Structural & Molecular Biology
, vol.21
, pp. 236-243
-
-
Sadeghi, L.1
Siggens, L.2
Svensson, J.P.3
Ekwall, K.4
-
98
-
-
77953060092
-
Structural insights into the assembly and function of the SAGA deubiquitinating module
-
Samara NL, Datta AB, Berndsen CE, Zhang X, Yao T, Cohen RE & Wolberger C 2010 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science 328 1025-1029. (doi:10.1126/science.1190049)
-
(2010)
Science
, vol.328
, pp. 1025-1029
-
-
Samara, N.L.1
Datta, A.B.2
Berndsen, C.E.3
Zhang, X.4
Yao, T.5
Cohen, R.E.6
Wolberger, C.7
-
99
-
-
84878753817
-
Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1
-
Sarkari F, Wheaton K, La Delfa A, Mohamed M, Shaikh F, Khatun R, Arrowsmith CH, Frappier L, Saridakis V & Sheng Y 2013 Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. Journal of Biological Chemistry 288 16975-16985. (doi:10.1074/jbc.M113.469262)
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 16975-16985
-
-
Sarkari, F.1
Wheaton, K.2
La Delfa, A.3
Mohamed, M.4
Shaikh, F.5
Khatun, R.6
Arrowsmith, C.H.7
Frappier, L.8
Saridakis, V.9
Sheng, Y.10
-
100
-
-
84892694492
-
USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
-
Schrecengost RS, Dean JL, Goodwin JF, Schiewer MJ, Urban MW, Stanek TJ, Sussman RT, Hicks JL, Birbe RC, Draganova-Tacheva RA et al. 2014 USP22 regulates oncogenic signaling pathways to drive lethal cancer progression. Cancer Research 74 272-286. (doi:10.1158/0008-5472.CAN-13-1954)
-
(2014)
Cancer Research
, vol.74
, pp. 272-286
-
-
Schrecengost, R.S.1
Dean, J.L.2
Goodwin, J.F.3
Schiewer, M.J.4
Urban, M.W.5
Stanek, T.J.6
Sussman, R.T.7
Hicks, J.L.8
Birbe, R.C.9
Draganova-Tacheva, R.A.10
-
101
-
-
84892562030
-
USP3 counteracts RNF168 via deubiquitinating H2A and gH2AX at lysine 13 and 15
-
Sharma N, Zhu Q, Wani G, He J, Wang QE & Wani AA 2014 USP3 counteracts RNF168 via deubiquitinating H2A and gH2AX at lysine 13 and 15. Cell Cycle 13 106-114. (doi:10.4161/cc.26814)
-
(2014)
Cell Cycle
, vol.13
, pp. 106-114
-
-
Sharma, N.1
Zhu, Q.2
Wani, G.3
He, J.4
Wang, Q.E.5
Wani, A.A.6
-
102
-
-
84861872358
-
Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function
-
Shchebet A, Karpiuk O, Kremmer E, Eick D & Johnsen SA 2012 Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function. Cell Cycle 11 2122-2127. (doi:10.4161/cc.20548)
-
(2012)
Cell Cycle
, vol.11
, pp. 2122-2127
-
-
Shchebet, A.1
Karpiuk, O.2
Kremmer, E.3
Eick, D.4
Johnsen, S.A.5
-
103
-
-
53549112774
-
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression
-
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G et al. 2008 The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes and Development 22 2664-2676. (doi:10.1101/gad.1703008)
-
(2008)
Genes and Development
, vol.22
, pp. 2664-2676
-
-
Shema, E.1
Tirosh, I.2
Aylon, Y.3
Huang, J.4
Ye, C.5
Moskovits, N.6
Raver-Shapira, N.7
Minsky, N.8
Pirngruber, J.9
Tarcic, G.10
-
104
-
-
79955946995
-
RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression
-
Shema E, Kim J, Roeder RG & Oren M 2011 RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. Molecular Cell 42 477-488. (doi:10.1016/j.molcel.2011.03.011)
-
(2011)
Molecular Cell
, vol.42
, pp. 477-488
-
-
Shema, E.1
Kim, J.2
Roeder, R.G.3
Oren, M.4
-
105
-
-
84881612908
-
Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription
-
Shema-Yaacoby E, Nikolov M, Haj-Yahya M, Siman P, Allemand E, Yamaguchi Y, Muchardt C, Urlaub H, Brik A, Oren M et al. 2013 Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Reports 4 601-608. (doi:10.1016/j.celrep.2013.07.014)
-
(2013)
Cell Reports
, vol.4
, pp. 601-608
-
-
Shema-Yaacoby, E.1
Nikolov, M.2
Haj-Yahya, M.3
Siman, P.4
Allemand, E.5
Yamaguchi, Y.6
Muchardt, C.7
Urlaub, H.8
Brik, A.9
Oren, M.10
-
106
-
-
80052779612
-
RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response
-
Shiloh Y, Shema E, Moyal L & Oren M 2011 RNF20-RNF40: a ubiquitin-driven link between gene expression and the DNA damage response. FEBS Letters 585 2795-2802. (doi:10.1016/j.febslet.2011.07.034)
-
(2011)
FEBS Letters
, vol.585
, pp. 2795-2802
-
-
Shiloh, Y.1
Shema, E.2
Moyal, L.3
Oren, M.4
-
107
-
-
54249106271
-
Deubiquitylating enzymes and disease
-
Singhal S, Taylor MC & Baker RT 2008 Deubiquitylating enzymes and disease. BMC Biochemistry 9 (Suppl 1) S3. (doi:10.1186/1471-2091-9-S1-S3)
-
(2008)
BMC Biochemistry
, vol.9
, pp. S3
-
-
Singhal, S.1
Taylor, M.C.2
Baker, R.T.3
-
108
-
-
78649922622
-
The chromatin signaling pathway: Diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes
-
Smith E & Shilatifard A 2010 The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes. Molecular Cell 40 689-701. (doi:10.1016/j.molcel.2010.11.031)
-
(2010)
Molecular Cell
, vol.40
, pp. 689-701
-
-
Smith, E.1
Shilatifard, A.2
-
109
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP & Harper JW 2009 Defining the human deubiquitinating enzyme interaction landscape. Cell 138 389-403. (doi:10.1016/j.cell.2009.04.042)
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
110
-
-
42149146774
-
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
-
Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA et al. 2008 DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Molecular and Cellular Biology 28 2825-2839. (doi:10.1128/MCB.02076-07)
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 2825-2839
-
-
Steger, D.J.1
Lefterova, M.I.2
Ying, L.3
Stonestrom, A.J.4
Schupp, M.5
Zhuo, D.6
Vakoc, A.L.7
Kim, J.E.8
Chen, J.9
Lazar, M.A.10
-
111
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun ZW & Allis CD 2002 Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418 104-108. (doi:10.1038/nature00883)
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
112
-
-
84892735426
-
Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators
-
Tahara T, Yamamoto E, Madireddi P, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T et al. 2014 Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators. Gastroenterology 146 530-538.e5. (doi:10.1053/j.gastro.2013.10.060)
-
(2014)
Gastroenterology
, vol.146
, pp. 530-538e5
-
-
Tahara, T.1
Yamamoto, E.2
Madireddi, P.3
Suzuki, H.4
Maruyama, R.5
Chung, W.6
Garriga, J.7
Jelinek, J.8
Yamano, H.O.9
Sugai, T.10
-
113
-
-
75149113640
-
BRCA1/BARD1 E3 ubiquitin ligase can modify histones H2A and H2B in the nucleosome particle
-
Thakar A, Parvin JD & Zlatanova J 2010 BRCA1/BARD1 E3 ubiquitin ligase can modify histones H2A and H2B in the nucleosome particle. Journal of Biomolecular Structure & Dynamics 27 399-406. (doi:10.1080/07391102.2010.10507326)
-
(2010)
Journal of Biomolecular Structure & Dynamics
, vol.27
, pp. 399-406
-
-
Thakar, A.1
Parvin, J.D.2
Zlatanova, J.3
-
114
-
-
84870912857
-
A role for H2B ubiquitylation in DNA replication
-
Trujillo KM & Osley MA 2012 A role for H2B ubiquitylation in DNA replication. Molecular Cell 48 734-746. (doi:10.1016/j.molcel.2012.09.019)
-
(2012)
Molecular Cell
, vol.48
, pp. 734-746
-
-
Trujillo, K.M.1
Osley, M.A.2
-
115
-
-
84861208532
-
Coupling of glucose deprivation with impaired histone H2B monoubiquitination in tumors
-
Urasaki Y, Heath L & Xu CW 2012 Coupling of glucose deprivation with impaired histone H2B monoubiquitination in tumors. PLoS ONE 7 e36775. (doi:10.1371/journal.pone.0036775)
-
(2012)
PLoS ONE
, vol.7
-
-
Urasaki, Y.1
Heath, L.2
Xu, C.W.3
-
116
-
-
27644506613
-
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
-
Varambally S, Yu J, Laxman B, Rhodes DR, Mehra R, Tomlins SA, Shah RB, Chandran U, Monzon FA, Becich MJ et al. 2005 Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell 8 393-406. (doi:10.1016/j.ccr.2005.10.001)
-
(2005)
Cancer Cell
, vol.8
, pp. 393-406
-
-
Varambally, S.1
Yu, J.2
Laxman, B.3
Rhodes, D.R.4
Mehra, R.5
Tomlins, S.A.6
Shah, R.B.7
Chandran, U.8
Monzon, F.A.9
Becich, M.J.10
-
117
-
-
84863229355
-
Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation
-
Vethantham V, Yang Y, Bowman C, Asp P, Lee JH, Skalnik DG & Dynlacht BD 2012 Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation. Molecular and Cellular Biology 32 1044-1055. (doi:10.1128/MCB.06026-11)
-
(2012)
Molecular and Cellular Biology
, vol.32
, pp. 1044-1055
-
-
Vethantham, V.1
Yang, Y.2
Bowman, C.3
Asp, P.4
Lee, J.H.5
Skalnik, D.G.6
Dynlacht, B.D.7
-
118
-
-
84862829634
-
Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases
-
Wakeman TP, Wang Q, Feng J & Wang XF 2012 Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases. EMBO Journal 31 2169-2181. (doi:10.1038/emboj.2012.50)
-
(2012)
EMBO Journal
, vol.31
, pp. 2169-2181
-
-
Wakeman, T.P.1
Wang, Q.2
Feng, J.3
Wang, X.F.4
-
119
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S, Cui K, Roh TY, Peng W, Zhang MQ et al. 2008 Combinatorial patterns of histone acetylations and methylations in the human genome. Nature Genetics 40 897-903. (doi:10.1038/ng.154)
-
(2008)
Nature Genetics
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
Roh, T.Y.8
Peng, W.9
Zhang, M.Q.10
-
120
-
-
84874638746
-
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia
-
Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG & Vakoc CR 2013a Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia. PNAS 110 3901-3906. (doi:10.1073/pnas. 1301045110)
-
(2013)
PNAS
, vol.110
, pp. 3901-3906
-
-
Wang, E.1
Kawaoka, S.2
Yu, M.3
Shi, J.4
Ni, T.5
Yang, W.6
Zhu, J.7
Roeder, R.G.8
Vakoc, C.R.9
-
121
-
-
84878726206
-
Prognostic significance of USP22 as an oncogene in papillary thyroid carcinoma
-
Wang H, Li YP, Chen JH, Yuan SF, Wang L, Zhang JL, Yao Q, Li NL, Bian JF, Fan J et al. 2013b Prognostic significance of USP22 as an oncogene in papillary thyroid carcinoma. Tumour Biology 34 1635-1639. (doi:10.1007/s13277-013-0696-0)
-
(2013)
Tumour Biology
, vol.34
, pp. 1635-1639
-
-
Wang, H.1
Li, Y.P.2
Chen, J.H.3
Yuan, S.F.4
Wang, L.5
Zhang, J.L.6
Yao, Q.7
Li, N.L.8
Bian, J.F.9
Fan, J.10
-
122
-
-
40849106789
-
Histone ubiquitination: Triggering gene activity
-
Weake VM & Workman JL 2008 Histone ubiquitination: triggering gene activity. Molecular Cell 29 653-663. (doi:10.1016/j.molcel.2008.02.014)
-
(2008)
Molecular Cell
, vol.29
, pp. 653-663
-
-
Weake, V.M.1
Workman, J.L.2
-
123
-
-
27744592390
-
Cross-talking histones: Implications for the regulation of gene expression and DNA repair
-
Wood A, Schneider J & Shilatifard A 2005 Cross-talking histones: implications for the regulation of gene expression and DNA repair. Biochemistry and Cell Biology 83 460-467. (doi:10.1139/o05-116)
-
(2005)
Biochemistry and Cell Biology
, vol.83
, pp. 460-467
-
-
Wood, A.1
Schneider, J.2
Shilatifard, A.3
-
124
-
-
80053440049
-
Flickin' the ubiquitin switch: The role of H2B ubiquitylation in development
-
Wright DE, Wang CY & Kao CF 2011 Flickin' the ubiquitin switch: the role of H2B ubiquitylation in development. Epigenetics 6 1165-1175. (doi:10.4161/epi.6.10.17745)
-
(2011)
Epigenetics
, vol.6
, pp. 1165-1175
-
-
Wright, D.E.1
Wang, C.Y.2
Kao, C.F.3
-
125
-
-
79959864524
-
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation
-
Wu L, Zee BM, Wang Y, Garcia BA & Dou Y 2011 The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Molecular Cell 43 132-144. (doi:10.1016/j.molcel.2011.05.015)
-
(2011)
Molecular Cell
, vol.43
, pp. 132-144
-
-
Wu, L.1
Zee, B.M.2
Wang, Y.3
Garcia, B.A.4
Dou, Y.5
-
126
-
-
69249229478
-
USP15 plays an essential role for caspase-3 activation during paclitaxel-induced apoptosis
-
Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M & Kuroda M 2009 USP15 plays an essential role for caspase-3 activation during paclitaxel-induced apoptosis. Biochemical and Biophysical Research Communications 388 366-371. (doi:10.1016/j.bbrc.2009.08.015)
-
(2009)
Biochemical and Biophysical Research Communications
, vol.388
, pp. 366-371
-
-
Xu, M.1
Takanashi, M.2
Oikawa, K.3
Tanaka, M.4
Nishi, H.5
Isaka, K.6
Kudo, M.7
Kuroda, M.8
-
127
-
-
47949107720
-
BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells
-
Yan Z, Wang Z, Sharova L, Sharov AA, Ling C, Piao Y, Aiba K, Matoba R, Wang W & Ko MS 2008 BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells. Stem Cells 26 1155-1165. (doi:10.1634/stemcells. 2007-0846)
-
(2008)
Stem Cells
, vol.26
, pp. 1155-1165
-
-
Yan, Z.1
Wang, Z.2
Sharova, L.3
Sharov, A.A.4
Ling, C.5
Piao, Y.6
Aiba, K.7
Matoba, R.8
Wang, W.9
Ko, M.S.10
-
128
-
-
81155134058
-
The co-expression of USP22 and BMI-1 may promote cancer progression and predict therapy failure in gastric carcinoma
-
Yang DD, Cui BB, Sun LY, Zheng HQ, Huang Q, Tong JX & Zhang QF 2011 The co-expression of USP22 and BMI-1 may promote cancer progression and predict therapy failure in gastric carcinoma. Cell Biochemistry and Biophysics 61 703-710. (doi:10.1007/s12013-011-9229-x)
-
(2011)
Cell Biochemistry and Biophysics
, vol.61
, pp. 703-710
-
-
Yang, D.D.1
Cui, B.B.2
Sun, L.Y.3
Zheng, H.Q.4
Huang, Q.5
Tong, J.X.6
Zhang, Q.F.7
-
129
-
-
84899089765
-
Ubiquitin-specific protease 22: A novel molecular biomarker in cervical cancer prognosis and therapeutics
-
Yang M, Liu YD, Wang YY, Liu TB, Ge TT & Lou G 2014 Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics. Tumour Biology 35 929-934. (doi:10.1007/s13277-013-1121-4)
-
(2014)
Tumour Biology
, vol.35
, pp. 929-934
-
-
Yang, M.1
Liu, Y.D.2
Wang, Y.Y.3
Liu, T.B.4
Ge, T.T.5
Lou, G.6
-
130
-
-
20344391925
-
The HRPT2tumor suppressor geneproductparafibromin associates with human PAF1 and RNA polymerase II
-
Yart A, Gstaiger M, Wirbelauer C, Pecnik M, Anastasiou D, Hess D & Krek W 2005 The HRPT2tumor suppressor geneproductparafibromin associates with human PAF1 and RNA polymerase II. Molecular and Cellular Biology 25 5052-5060. (doi:10.1128/MCB.25.12.5052-5060.2005)
-
(2005)
Molecular and Cellular Biology
, vol.25
, pp. 5052-5060
-
-
Yart, A.1
Gstaiger, M.2
Wirbelauer, C.3
Pecnik, M.4
Anastasiou, D.5
Hess, D.6
Krek, W.7
-
131
-
-
79951488010
-
WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription
-
Zhang F & Yu X 2011 WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription. Molecular Cell 41 384-397. (doi:10.1016/j.molcel.2011.01.024)
-
(2011)
Molecular Cell
, vol.41
, pp. 384-397
-
-
Zhang, F.1
Yu, X.2
-
132
-
-
84863795475
-
One stone, two birds: Cdk9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA
-
Zhang H & Yu DS 2012 One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA. Cell Cycle 11 2418. (doi:10.4161/cc.21068)
-
(2012)
Cell Cycle
, vol.11
, pp. 2418
-
-
Zhang, H.1
Yu, D.S.2
-
133
-
-
38149078715
-
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression
-
Zhang XY, Varthi M, Sykes SM, Phillips C, Warzecha C, Zhu W, Wyce A, Thorne AW, Berger SL & McMahon SB 2008 The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular Cell 29 102-111. (doi:10.1016/j.molcel.2007.12.015)
-
(2008)
Molecular Cell
, vol.29
, pp. 102-111
-
-
Zhang, X.Y.1
Varthi, M.2
Sykes, S.M.3
Phillips, C.4
Warzecha, C.5
Zhu, W.6
Wyce, A.7
Thorne, A.W.8
Berger, S.L.9
McMahon, S.B.10
-
134
-
-
79961170767
-
Elevated expression of USP22 in correlation with poor prognosis in patients with invasive breast cancer
-
Zhang Y, Yao L, Zhang X, Ji H, Wang L, Sun S & Pang D 2011a Elevated expression of USP22 in correlation with poor prognosis in patients with invasive breast cancer. Journal of Cancer Research and Clinical Oncology 137 1245-1253. (doi:10.1007/s00432-011-0998-9)
-
(2011)
Journal of Cancer Research and Clinical Oncology
, vol.137
, pp. 1245-1253
-
-
Zhang, Y.1
Yao, L.2
Zhang, X.3
Ji, H.4
Wang, L.5
Sun, S.6
Pang, D.7
-
135
-
-
80051654271
-
Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia
-
Zhang Y, van Deursen J & Galardy PJ 2011b Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia. PLoS ONE 6 e23389. (doi:10.1371/journal.pone.0023389)
-
(2011)
PLoS ONE
, vol.6
-
-
Zhang, Y.1
Van Deursen, J.2
Galardy, P.J.3
-
136
-
-
84870562210
-
USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis
-
Zhang Y, Foreman O, Wigle DA, Kosari F, Vasmatzis G, Salisbury JL, van Deursen J & Galardy PJ 2012 USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis. Journal of Clinical Investigation 122 4362-4374. (doi:10.1172/JCI63084)
-
(2012)
Journal of Clinical Investigation
, vol.122
, pp. 4362-4374
-
-
Zhang, Y.1
Foreman, O.2
Wigle, D.A.3
Kosari, F.4
Vasmatzis, G.5
Salisbury, J.L.6
Van Deursen, J.7
Galardy, P.J.8
-
137
-
-
84880424207
-
USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing
-
Zhang Z, Jones A, Joo HY, Zhou D, Cao Y, Chen S, Erdjument-Bromage H, Renfrow M, He H, Tempst P et al. 2013 USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing. Genes and Development 27 1581-1595. (doi:10.1101/gad.211037.112)
-
(2013)
Genes and Development
, vol.27
, pp. 1581-1595
-
-
Zhang, Z.1
Jones, A.2
Joo, H.Y.3
Zhou, D.4
Cao, Y.5
Chen, S.6
Erdjument-Bromage, H.7
Renfrow, M.8
He, H.9
Tempst, P.10
-
138
-
-
27944454433
-
Monoubiquitination of human histone H2B: The factors involved and their roles in HOX gene regulation
-
Zhu B, Zheng Y, Pham AD, Mandal SS, Erdjument-Bromage H, Tempst P & Reinberg D 2005 Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Molecular Cell 20 601-611. (doi:10.1016/j.molcel.2005.09.025)
-
(2005)
Molecular Cell
, vol.20
, pp. 601-611
-
-
Zhu, B.1
Zheng, Y.2
Pham, A.D.3
Mandal, S.S.4
Erdjument-Bromage, H.5
Tempst, P.6
Reinberg, D.7
-
139
-
-
80052567822
-
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
-
Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH & Verma IM 2011 BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature 477 179-184. (doi:10.1038/nature10371)
-
(2011)
Nature
, vol.477
, pp. 179-184
-
-
Zhu, Q.1
Pao, G.M.2
Huynh, A.M.3
Suh, H.4
Tonnu, N.5
Nederlof, P.M.6
Gage, F.H.7
Verma, I.M.8
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