USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

Genes and Development

Volumn 27, Issue 14, 2013, Pages 1581-1595

  Zhang, Zhuo ^a   Jones, Amanda ^a   Joo, Heui Yun ^a   Zhou, Dewang ^a   Cao, Ying ^b   Chen, Shaoxia ^c   Erdjument Bromage, Hediye ^d   Renfrow, Matthew ^a   He, Hang ^c   Tempst, Paul ^d   Townes, Tim M ^a   Giles, Keith E ^a   Ma, Ligeng ^e   Wang, Hengbin ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b HEBEI NORMAL UNIVERSITY   (China)

^c PEKING UNIVERSITY   (China)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e CAPITAL NORMAL UNIVERSITY   (China)

Author keywords

H2B deubiquitination; Pre mRNA splicing; Transcription; USP49

Indexed keywords

HISTONE H2B; RNA; UBIQUITIN; UBIQUITIN SPECIFIC PEPTIDASE 49; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CHROMATIN; CONTROLLED STUDY; DOWN REGULATION; EUKARYOTE; EXON; GENE EXPRESSION; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN PURIFICATION; REGULATORY MECHANISM; RNA SPLICING; RNA TRANSCRIPTION;

H2B DEUBIQUITINATION; PRE-MRNA SPLICING; TRANSCRIPTION; USP49;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; CELL LINE, TUMOR; DNA HELICASES; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HISTONES; HUMANS; LIM DOMAIN PROTEINS; RNA PRECURSORS; RNA SPLICING; TRANSCRIPTION FACTORS; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84880424207     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.211037.112     Document Type: Article

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