Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast

BioFactors

Volumn 41, Issue 1, 2015, Pages 15-27

  Moglia, Andrea ^a,b   Goitre, Luca ^b,c   Gianoglio, Silvia ^a,b   Baldini, Eva ^b,d   Trapani, Eliana ^b,c   Genre, Andrea ^a   Scattina, Antonella ^e   Dondo, Giancarlo ^e   Trabalzini, Lorenza ^b,d   Beekwilder, Jules ^f   Retta, Saverio Francesco ^b,c  

^a UNIVERSITY OF TURIN   (Italy)

^b CCM Italia Research Network   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

^e CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

^f WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Antioxidants; Avenanthramides; Biofactors; Cerebral cavernous malformation; Metabolic engineering; Phenolic compounds; Plant secondary metabolites; Saccharomyces cerevisiae

Indexed keywords

AMIDE; CYCLIN D1; EXTRACELLULAR SUPEROXIDE DISMUTASE; N 4 COUMAROYL 3 HYDROXYANTHRANILIC ACID; N CAFFEOYL 3 HYDROXYANTHRANILIC ACID; PHENOL DERIVATIVE; PROTEIN SOD 2; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; ANTHRANILIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; AVENANTHRAMIDE-2C; CCND1 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CAVERNOUS HEMANGIOMA; CELL VIABILITY; DOWN REGULATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FERMENTATION; FIBROBLAST CULTURE; FUNGAL STRAIN; HELA CELL LINE; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; MOUSE; NONHUMAN; PHENOTYPE; PLANT GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; UPREGULATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTICHOKE; BIOLOGICAL MODEL; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; SIGNAL TRANSDUCTION; TOBACCO; TRANSFORMED CELL LINE; TRANSGENE; TRANSPORT AT THE CELLULAR LEVEL;

CYNARA SCOLYMUS; NICOTIANA TABACUM; SACCHAROMYCES CEREVISIAE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; BIOLOGICAL TRANSPORT; CELL LINE, TRANSFORMED; CYCLIN D1; CYNARA SCOLYMUS; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENES, PLANT; HELA CELLS; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; METABOLIC ENGINEERING; MICE; MODELS, BIOLOGICAL; ORTHO-AMINOBENZOATES; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TOBACCO; TRANSGENES;

EID: 84923531438     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1197     Document Type: Article

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