KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun

Free Radical Biology and Medicine

Volumn 68, Issue , 2014, Pages 134-147

  Goitre, Luca ^a   De Luca, Elisa ^a   Braggion, Stefano ^a   Trapani, Eliana ^a   Guglielmotto, Michela ^b   Biasi, Fiorella ^a   Forni, Marco ^c   Moglia, Andrea ^b   Trabalzini, Lorenza ^d   Retta, Saverio Francesco ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c EuroClone SpA Research Laboratory   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

Author keywords

c Jun; Cellular antioxidant defense mechanisms; Cerebral cavernous malformations; COX 2; Free radicals; KRIT1; Reactive oxygen species

Indexed keywords

CYCLOOXYGENASE 2; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CAVERNOUS HEMANGIOMA; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION;

C-JUN; CELLULAR ANTIOXIDANT DEFENSE MECHANISMS; CEREBRAL CAVERNOUS MALFORMATIONS; COX-2; FREE RADICALS; KRIT1; REACTIVE OXYGEN SPECIES;

ANIMALS; GENE EXPRESSION REGULATION; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES;

EID: 84891613017     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.11.020     Document Type: Article

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