P70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake

Cell Metabolism

Volumn 16, Issue 1, 2012, Pages 104-112

  Dagon, Yossi ^a   Hur, Elizabeth ^a   Zheng, Bin ^a,b   Wellenstein, Kerry ^a   Cantley, Lewis C ^a   Kahn, Barbara B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ALPHA 2 AMP KINASE; ANOREXIGENIC AGENT; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; NEUROPEPTIDE; P70S6 KINASE; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL GROWTH; CELL MATURATION; CELL METABOLISM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; FOOD INTAKE; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENYLATE KINASE; AGOUTI-RELATED PROTEIN; ANIMALS; BODY WEIGHT; CELL LINE; EATING; HYPOTHALAMUS; LEPTIN; MALE; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PRO-OPIOMELANOCORTIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SERINE; SIGNAL TRANSDUCTION;

EID: 84863535512     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.05.010     Document Type: Article

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