Glutathione peroxidase 8 is transcriptionally regulated by HIFα and modulates growth factor signaling in HeLa cells

Free Radical Biology and Medicine

Volumn 81, Issue , 2015, Pages 58-68

  Bosello Travain, Valentina ^a   Forman, Henry J ^b   Roveri, Antonella ^a   Toppo, Stefano ^a   Ursini, Fulvio ^a   Venerando, Rina ^a   Warnecke, Christina ^c   Zaccarin, Mattia ^a   Maiorino, Matilde ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Endoplasmic reticulum; Free radicals; GPx8; Hydroperoxide; Hypoxia; Receptor tyrosine kinase; Redox Signaling

Indexed keywords

FIBROBLAST GROWTH FACTOR; GLUTATHIONE PEROXIDASE 8; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOREDUCTASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STABILIZING AGENT; UNCLASSIFIED DRUG; 2,2' BIPYRIDINE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DIETHYL SUCCINATE; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; GPX8 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYBRID PROTEIN; INSULIN; LUCIFERASE; MAPK1 PROTEIN, HUMAN; PEROXIDASE; SUCCINIC ACID DERIVATIVE;

ARTICLE; CELL HYPOXIA; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DNA STRUCTURE; ENDOPLASMIC RETICULUM; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; GENETIC TRANSFECTION; HELA CELL LINE; HUMAN; HUMAN CELL; HYPOXIA RESPONSE ELEMENT; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; SEQUENCE ALIGNMENT;

MAMMALIA;

2,2'-DIPYRIDYL; AMINO ACID SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; ENDOPLASMIC RETICULUM; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GENES, REPORTER; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR SEQUENCE DATA; PEROXIDASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RECOMBINANT FUSION PROTEINS; RESPONSE ELEMENTS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SUCCINATES; TRANSCRIPTION, GENETIC;

EID: 84923354606     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.12.020     Document Type: Article

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