UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy

Cellular Signalling

Volumn 27, Issue 5, 2015, Pages 908-922

  Wang, Li ^a   Burmeister, Brian T ^a   Johnson, Keven R ^a   Baillie, George S ^d   Karginov, Andrei V ^a,b   Skidgel, Randal A ^a   O'Bryan, John P ^a,b,c   Carnegie, Graeme K ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

3',5' cyclic monophosphate (cAMP); A kinase anchoring protein (AKAP); Cardiomyocyte hypertrophy; Compartmentalized signaling; Phosphodiesterase 4 (PDE4) activation; Protein kinase A (PKA)

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENZYME ACTIVATOR; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPROTEIN; PEPTIDE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SIZE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; HEART HYPERTROPHY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPSTREAM CONSERVED REGION 1; AMINO ACID SEQUENCE; ANIMAL; CARDIOMEGALY; CHEMISTRY; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHOSPHORYLATION;

A KINASE ANCHOR PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MYOCYTES, CARDIAC; PEPTIDES; PHOSPHORYLATION; PROTEIN ISOFORMS; RATS; SIGNAL TRANSDUCTION;

EID: 84923333459     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.02.003     Document Type: Article

References (64)

1. Hill J.A., Olson E.N. N. Engl. J. Med. 2008, 358:1370-1380.
2. Selvetella G., Hirsch E., Notte A., Tarone G., Lembo G. Cardiovasc. Res. 2004, 63:373-380.
3. Frey N., Katus H.A., Olson E.N., Hill J.A. Circulation 2004, 109:1580-1589.
4. Frey N., Olson E.N. Annu. Rev. Physiol. 2003, 65:45-79.
5. Heineke J., Molkentin J.D. Nat. Rev. Mol. Cell Biol. 2006, 7:589-600.
6. Mudd J.O., Kass D.A. Nature 2008, 451:919-928.
7. Jiang D.S., Bian Z.Y., Zhang Y., Zhang S.M., Liu Y., Zhang R., Chen Y., Yang Q., Zhang X.D., Fan G.C., Li H. Hypertension 2013, 61:1193-1202.
8. Itaya T., Hashimoto H., Uematsu T., Nakashima M. Br. J. Pharmacol. 1990, 99:572-576.
9. Laurent A.C., Breckler M., Berthouze M., Lezoualc'h F. Biochem. Soc. Trans. 2012, 40:51-57.
10. Houslay M.D. Trends Biochem. Sci. 2010, 35:91-100.
11. Enns L.C., Bible K.L., Emond M.J., Ladiges W.C. BMC Res. Notes 2010, 3:307.
12. Zaccolo M., Pozzan T. Science 2002, 295:1711-1715.
13. Zaccolo M. Br. J. Pharmacol. 2009, 158:50-60.
14. Kapiloff M.S., Chandrasekhar K.D. J. Cardiovasc. Pharmacol. 2011, 58:337-338.
15. Guellich A., Mehel H., Fischmeister R. Pflugers Arch. 2014, 466:1163-1175.
16. Matsumoto T., Kobayashi T., Kamata K. J. Smooth Muscle Res. 2003, 39:67-86.
17. Fields L.A. local cAMP signaling and phosphodiesterase activity in an in vitro model of cardiac hypertrophy 2013, Univeristy of Glasgow, PhD thesis.
18. Lehnart S.E., Wehrens X.H., Reiken S., Warrier S., Belevych A.E., Harvey R.D., Richter W., Jin S.L., Conti M., Marks A.R. Cell 2005, 123:25-35.
19. Richter W., Xie M., Scheitrum C., Krall J., Movsesian M.A., Conti M. Basic Res. Cardiol. 2011, 106:249-262.
20. Lehnart S.E., Marks A.R. Expert Opin. Ther. Targets 2006, 10:677-688.
21. Lim J., Pahlke G., Conti M. J. Biol. Chem. 1999, 274:19677-19685.
22. Sheppard C.L., Lee L.C., Hill E.V., Henderson D.J., Anthony D.F., Houslay D.M., Yalla K.C., Cairns L.S., Dunlop A.J., Baillie G.S., Huston E., Houslay M.D. Cell. Signal. 2014, 26:1958-1974.
23. MacKenzie S.J., Baillie G.S., McPhee I., MacKenzie C., Seamons R., McSorley T., Millen J., Beard M.B., van Heeke G. Br. J. Pharmacol. 2002, 136:421-433.
24. Baillie G.S., MacKenzie S.J., McPhee I., Houslay M.D. Br. J. Pharmacol. 2000, 131:811-819.
25. Hoffmann R., Baillie G.S., MacKenzie S.J., Yarwood S.J., Houslay M.D. EMBO J. 1999, 18:893-903.
26. Omori K., Kotera J. Circ. Res. 2007, 100:309-327.
27. Grange M., Sette C., Cuomo M., Conti M., Lagarde M., Prigent A.F., Nemoz G. J. Biol. Chem. 2000, 275:33379-33387.
28. Diviani D., Dodge-Kafka K.L., Li J., Kapiloff M.S. Am. J. Physiol. Heart Circ. Physiol. 2011, 301:H1742-H1753.
29. Carnegie G.K., Burmeister B.T. J. Cardiovasc. Pharmacol. 2011, 58:451-458.
30. Carnegie G.K., Means C.K., Scott J.D. IUBMB Life 2009, 61:394-406.
31. Colledge M., Scott J.D. Trends Cell Biol. 1999, 9:216-221.
32. Wong W., Scott J.D. Nat. Rev. Mol. Cell Biol. 2004, 5:959-970.
33. Beene D.L., Scott J.D. Curr. Opin. Cell Biol. 2007, 19:192-198.
34. Bristow M.R. Int. J. Cardiol. 1984, 5:648-652.
35. Antos C.L., Frey N., Marx S.O., Reiken S., Gaburjakova M., Richardson J.A., Marks A.R., Olson E.N. Circ. Res. 2001, 89:997-1004.
36. Bisognano J.D., Weinberger H.D., Bohlmeyer T.J., Pende A., Raynolds M.V., Sastravaha A., Roden R., Asano K., Blaxall B.C., Wu S.C., Communal C., Singh K., Colucci W., Bristow M.R., Port D.J. J. Mol. Cell. Cardiol. 2000, 32:817-830.
37. Burmeister B.T., Taglieri D.M., Wang L., Carnegie G.K. J. Biol. Chem. 2012, 287:40535-40546.
38. Edwards H.V., Scott J.D., Baillie G.S. Biochem. J. 2012, 446:437-443.
39. Carnegie G.K., Soughayer J., Smith F.D., Pedroja B.S., Zhang F., Diviani D., Bristow M.R., Kunkel M.T., Newton A.C., Langeberg L.K., Scott J.D. Mol. Cell 2008, 32:169-179.
40. Diviani D., Abuin L., Cotecchia S., Pansier L. EMBO J. 2004, 23:2811-2820.
41. Jin J., Smith F.D., Stark C., Wells C.D., Fawcett J.P., Kulkarni S., Metalnikov P., O'Donnell P., Taylor P., Taylor L., Zougman A., Woodgett J.R., Langeberg L.K., Scott J.D., Pawson T. Curr. Biol. 2004, 14:1436-1450.
42. Carnegie G.K., Smith F.D., McConnachie G., Langeberg L.K., Scott J.D. Mol. Cell 2004, 15:889-899.
43. Smith F.D., Langeberg L.K., Cellurale C., Pawson T., Morrison D.K., Davis R.J., Scott J.D. Nat. Cell Biol. 2010, 12:1242-1249.
44. Diviani D., Soderling J., Scott J.D. J. Biol. Chem. 2001, 276:44247-44257.
45. Pare G.C., Bauman A.L., McHenry M., Michel J.J., Dodge-Kafka K.L., Kapiloff M.S. J. Cell Sci. 2005, 118:5637-5646.
46. Beavo J.A., Hardman J.G., Sutherland E.W. J. Biol. Chem. 1970, 245:5649-5655.
47. Beca S., Helli P.B., Simpson J.A., Zhao D., Farman G.P., Jones P.P., Tian X., Wilson L.S., Ahmad F., Chen S.R., Movsesian M.A., Manganiello V., Maurice D.H., Conti M., Backx P.H. Circ. Res. 2011, 109:1024-1030.
48. Nemoz G., Sette C., Conti M. Mol. Pharmacol. 1997, 51:242-249.
49. Bolger G.B., Peden A.H., Steele M.R., MacKenzie C., McEwan D.G., Wallace D.A., Huston E., Baillie G.S., Houslay M.D. J. Biol. Chem. 2003, 278:33351-33363.
50. Millar J.K., Pickard B.S., Mackie S., James R., Christie S., Buchanan S.R., Malloy M.P., Chubb J.E., Huston E., Baillie G.S., Thomson P.A., Hill E.V., Brandon N.J., Rain J.C., Camargo L.M., Whiting P.J., Houslay M.D., Blackwood D.H., Muir W.J., Porteous D.J. Science 2005, 310:1187-1191.
51. Beard M.B., Olsen A.E., Jones R.E., Erdogan S., Houslay M.D., Bolger G.B. J. Biol. Chem. 2000, 275:10349-10358.
52. Haj Slimane Z., Bedioune I., Lechene P., Varin A., Lefebvre F., Mateo P., Domergue-Dupont V., Dewenter M., Richter W., Conti M., El-Armouche A., Zhang J., Fischmeister R., Vandecasteele G. Cardiovasc. Res. 2014, 102:97-106.
53. Wang L., Carnegie G.K. J. Vis. Exp. 2013, 78:50529. e1-9.
54. Meinkoth J.L., Alberts A.S., Went W., Fantozzi D., Taylor S.S., Hagiwara M., Montminy M., Feramisco J.R. Mol. Cell. Biochem. 1993, 127-128:179-186.
55. Yang J.H., Polanowska-Grabowska R.K., Smith J.S., Shields CWt, Saucerman J.J. J. Mol. Cell. Cardiol. 2014, 66:83-93.
56. Takahashi K., Osanai T., Nakano T., Wakui M., Okumura K. Heart Vessel. 2002, 16:249-256.
57. Mokni W., Keravis T., Etienne-Selloum N., Walter A., Kane M.O., Schini-Kerth V.B., Lugnier C. PLoS One 2010, 5:e14227.
58. Abi-Gerges A., Richter W., Lefebvre F., Mateo P., Varin A., Heymes C., Samuel J.L., Lugnier C., Conti M., Fischmeister R., Vandecasteele G. Circ. Res. 2009, 105:784-792.
59. Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., Marks A.R. Cell 2000, 101:365-376.
60. Burgin A.B., Magnusson O.T., Singh J., Witte P., Staker B.L., Bjornsson J.M., Thorsteinsdottir M., Hrafnsdottir S., Hagen T., Kiselyov A.S., Stewart L.J., Gurney M.E. Nat. Biotechnol. 2010, 28:63-70.
61. MacKenzie K.F., Wallace D.A., Hill E.V., Anthony D.F., Henderson D.J., Houslay D.M., Arthur J.S., Baillie G.S., Houslay M.D. Biochem. J. 2011, 435:755-769.
62. Metrich M., Morel E., Berthouze M., Pereira L., Charron P., Gomez A.M., Lezoualc'h F. Pharmacol. Rep. 2009, 61:146-153.
63. Sample V., DiPilato L.M., Yang J.H., Ni Q., Saucerman J.J., Zhang J. Nat. Chem. Biol. 2012, 8:375-382.
64. Dodge-Kafka K.L., Soughayer J., Pare G.C., Carlisle Michel J.J., Langeberg L.K., Kapiloff M.S., Scott J.D. Nature 2005, 437:574-578.