Exploring the early stages of the pH-induced conformational change of influenza hemagglutinin

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 10, 2014, Pages 2412-2428

  Zhou, Yu ^a,b   Wu, Chao ^b,c   Zhao, Lifeng ^b   Huang, Niu ^a,b  

^a BEIJING NORMAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Continuous constant pH molecular dynamics; Fusion inhibitor; Influenza hemagglutinin; Molecular dynamics simulation; PH induced conformational change

Indexed keywords

DIRIDAVUMAB; INFLUENZA VIRUS HEMAGGLUTININ;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DISULFIDE BOND; ENDOSOME; HINGE REGION; HYDROGEN BOND; HYDROPHOBICITY; INFLUENZA VIRUS; INFLUENZA VIRUS A; INFLUENZA VIRUS A H5N1; MEMBRANE FUSION; MOLECULAR DYNAMICS; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; SEQUENCE ALIGNMENT; STATIC ELECTRICITY; SURFACE CHARGE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; INFLUENZA; INFLUENZA A VIRUS; PHYSIOLOGY; PROTEIN CONFORMATION; VIROLOGY;

ORTHOMYXOVIRIDAE;

HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MEMBRANE FUSION; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION;

EID: 84923328182     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24606     Document Type: Article

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