β-secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion

Journal of Neuroscience

Volumn 35, Issue 8, 2015, Pages 3298-3311

  Hessler, Sabine ^a   Zheng, Fang ^a   Hartmann, Stephanie ^a   Rittger, Andrea ^b   Lehnert, Sandra ^a   Völkel, Meike ^b   Nissen, Matthias ^a   Edelmann, Elke ^b,c   Saftig, Paul ^b   Schwake, Michael ^b,d   Huth, Tobias ^a   Alzheimer, Christian ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d BIELEFELD UNIVERSITY   (Germany)

Author keywords

Alzheimer s disease; BACE1; Epilepsy; Hippocampus; KCNQ; M current

Indexed keywords

BETA SECRETASE 1; CADHERIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL KCNQ2; RETIGABINE; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; POTASSIUM CHANNEL KCNQ; PROTEIN BINDING; PROTEIN SUBUNIT; SECRETASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EVOKED RESPONSE; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NERVE EXCITABILITY; NONHUMAN; POLYMERASE CHAIN REACTION; POTASSIUM CURRENT; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; VOLTAGE CLAMP TECHNIQUE; WESTERN BLOTTING; ACTION POTENTIAL; ANIMAL; CELL CULTURE; CYTOLOGY; FEMALE; GENETICS; HEK293 CELL LINE; MALE; METABOLISM; PHYSIOLOGY; PROTEIN SUBUNIT;

ACTION POTENTIALS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CELLS, CULTURED; FEMALE; HEK293 CELLS; HIPPOCAMPUS; HUMANS; KCNQ POTASSIUM CHANNELS; MALE; MICE; PROTEIN BINDING; PROTEIN SUBUNITS; PYRAMIDAL CELLS;

EID: 84923328162     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3127-14.2015     Document Type: Article

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