Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons

Journal of Physiology

Volumn 589, Issue 24, 2011, Pages 6029-6038

  Shah, Mala M ^a   Migliore, Michele ^b   Brown, David A ^c  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b CNR   (Italy)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; ION CHANNEL; KV7 POTASSIUM CHANNEL; POTASSIUM CHANNEL; RETIGABINE; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; COGNITION; CONTROLLED STUDY; DENDRITE; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL PLASTICITY; NERVE FIBER; NONHUMAN; PERIKARYON; POTASSIUM CURRENT; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC POTENTIAL; WAVEFORM;

ACTION POTENTIALS; ANIMALS; AXONS; DENDRITES; EXCITATORY POSTSYNAPTIC POTENTIALS; KCNQ1 POTASSIUM CHANNEL; OLIGOPEPTIDES; PYRAMIDAL CELLS; RATS; SYNAPSES;

EID: 83455234756     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.220913     Document Type: Article

References (29)

1. Brown DA & Passmore GM (2009). Neural KCNQ (Kv7) channels. Br J Pharmacol 156, 1185-1195.
2. Chung HJ, Jan YN & Jan LY (2006). Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A 103, 8870-8875.
3. Clark B & Hausser M (2006). Neural coding: hybrid analog and digital signalling in axons. Curr Biol 16, R585-R588.
4. Debanne D (2004). Information processing in the axon. Nat Rev 5, 304-316.
5. Delmas P & Brown DA (2005). Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev 6, 850-862.
6. + channel. J Neurosci 24, 1236-1244.
7. Goldman AM, Glasscock E, Yoo J, Chen TT, Klassen TL & Noebels JL (2009). Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death. Sci Transl Med 1, 2ra6.
8. Hines ML & Carnevale NT (1997). The NEURON simulation environment. Neural Comput 9, 1179-1209.
9. Hu H, Vervaeke K & Storm JF (2007). M-channels (Kv7/KCNQ channels) that regulate synaptic integration, excitability, and spike pattern of CA1 pyramidal cells are located in the perisomatic region. J Neurosci 27, 1853-1867.
10. Huang H & Trussell LO (2011). KCNQ5 channels control resting properties and release probability of a synapse. Nat Neurosci 14, 840-847.
11. Jentsch TJ (2000). Neuronal KCNQ potassium channels: physiology and role in disease. Nat Rev 1, 21-30.
12. 2+ channels. J Neurochem 109, 168-181.
13. Magee JC (2000). Dendritic integration of excitatory synaptic input. Nat Rev 1, 181-190.
14. Marder E & Goaillard JM (2006). Variability, compensation and homeostasis in neuron and network function. Nat Rev 7, 563-574.
15. Martire M, Castaldo P, D'Amico M, Preziosi P, Annunziato L & Taglialatela M (2004). M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals. J Neurosci 24, 592-597.
16. Migliore M, Ferrante M & Ascoli GA (2005). Signal propagation in oblique dendrites of CA1 pyramidal cells. J Neurophysiol 94, 4145-4155.
17. Migliore M, Morse TM, Davison AP, Marenco L, Shepherd GM & Hines ML (2003). ModelDB: making models publicly accessible to support computational neuroscience. Neuroinformatics 1, 135-139.
18. Migliore M & Shepherd GM (2002). Emerging rules for the distributions of active dendritic conductances. Nat Rev Neurosci 3, 362-370.
19. Pan Z, Kao T, Horvath Z, Lemos J, Sul JY, Cranstoun SD, Bennett V, Scherer SS & Cooper EC (2006). A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. J Neurosci 26, 2599-2613.
20. Peretz A, Sheinin A, Yue C, Degani-Katzav N, Gibor G, Nachman R, Gopin A, Tam E, Shabat D, Yaari Y & Attali B (2007). Pre- and postsynaptic activation of M-channels by a novel opener dampens neuronal firing and transmitter release. J Neurophysiol 97, 283-295.
21. Peters HC, Hu H, Pongs O, Storm JF & Isbrandt D (2005). Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. Nat Neurosci 8, 51-60.
22. Poolos NP, Migliore M & Johnston D (2002). Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites. Nat Neurosci 5, 767-774.
23. + channels. Br J Pharmacol 137, 1173-1186.
24. Shah MM, Anderson AE, Leung V, Lin X & Johnston D (2004). Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons. Neuron 44, 495-508.
25. Shah MM, Migliore M, Valencia I, Cooper EC & Brown DA (2008). Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A 105, 7869-7874.
26. Shah MM, Mistry M, Marsh SJ, Brown DA & Delmas P (2002). Molecular correlates of the M-current in cultured rat hippocampal neurons. J Physiol 544, 29-37.
27. Tatulian L, Delmas P, Abogadie FC & Brown DA (2001). Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. J Neurosci 21, 5535-5545.
28. 2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity. J Neurophysiol 100, 1897-1908.
29. Yue C & Yaari Y (2006). Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells. J Neurophysiol 95, 3480-3495.