Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity

Journal of Biological Chemistry

Volumn 275, Issue 29, 2000, Pages 22395-22400

  Lerche, Christian ^a   Scherer, Constanze R ^a   Seebohm, Guiscard ^a   Derst, Christian ^b   Wei, Agaun D ^c   Busch, Andreas E ^a   Steinmeyer, Klaus ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINOPIRDINE; POTASSIUM CHANNEL; PROTEIN SUBUNIT; TETRYLAMMONIUM;

ARTICLE; GENE EXPRESSION; MEMBRANE CURRENT; MOLECULAR CLONING; NERVE CELL MEMBRANE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; HUMANS; ION TRANSPORT; KCNQ POTASSIUM CHANNELS; MOLECULAR SEQUENCE DATA; NEURONS; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SEQUENCE ALIGNMENT; VARIATION (GENETICS); XENOPUS;

EID: 0034698079     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M002378200     Document Type: Article

References (42)

1. Wang, Q., Curran, M. E., Splawski, I., Burn, T. C., Millholla, J. M., VanRaay, T. J., Shen, J., Timothy, K. W., Vincent, G. M., de Jager, T., Schwartz, P. J., Towbin, J. A., Moss, A. J., Atkinson, D. L., Landes, G. M., Connors T. D., and Keating, M. T. (1996) Nat. Genet. 12, 17-23
2. Takumi, T., Ohkubo, H., and Nakanishi, S. (1988) Science 242, 1042-1044
3. Attali, B. (1996) Nature 384, 24-25
4. Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., and Romey, G. (1996) Nature 384, 78-80
5. Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Spector, P. S., Atkinson, D. L., and Keating, M. T. (1996) Nature 384, 80-83
6. Yang, W.-P., Levesque, P. C., Little, W. A., Conder, M. L., Shalaby, F. Y., and Blanar, M. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4017-4021
7. Keating, M. T., and Sanguinetti, M. C. (1996) Science 272, 681-685
8. Chouabe, C., Neyroud, N., Guicheney, P., Lazdunski, M., Romey, G., and Barhanin, J. (1997) EMBO J. 16, 5472-5479
9. Sanguinetti, M. C. (1999) Ann. N. Y Acad. Sci. 868, 406-413
10. Suessbrich, H., and Busch, A. E. (1999) Rev. Physiol. Biochem. Pharmacol. 137, 191-226
11. Schulze-Bahr, E., Wang, Q., Wedekind, H., Haverkamp, W., Chen, Q., and Sun, Y. (1997) Nat. Genet. 17, 267-268
12. Neyroud, N., Tesson, F., Denjoy, I., Leibovici, M., Donger, C., Barhanin, J., Faure, S., Gary, F., Coumel, P., Petit, C., Schwartz, K., and Guicheney, P. (1997) Nat. Genet. 15, 186-189
13. Abbott, G. W., Sesti, F., Splawski, I., Buck, M. E., Lehmann, M. H., Timothy, K. W., Keating, M. T., and Goldstein, S. A. N. (1999) Cell 97, 175-187
14. Schröder, B. C., Waldegger, S., Fehr, S., Bleich, M., Warth, R., Greger, R., and Jentsch, T. J. (2000) Nature 403, 196-199
15. Lohrmann, E., Burhoff, I., Nitschke, R. B., Lang, H.-J., Mania, D., Englert, H. C., Hropot, M., Warth, R., Rohm, W., Bleich, M., and Greger, R. (1995) Pflügers Arch. 429, 517-530
16. Biervert, C., Schröder, B. C., Kubisch, C., Berkovic, S. F., Propping, P., Jentsch, T. J., and Steinlein, O. K. (1998) Science 279, 403-406
17. Schröder, B. C., Kubisch, C., Stein, V., and Jentsch, T. J. (1998) Nature 396, 687-690
18. Yang, W.-P., Levesque, P. C., Little, W. A., Conder, M. L., Ramakrishnan, P., Neubauer, M. G., and Blanar, M. A. (1998) J. Biol. Chem. 273, 19419-19423
19. Wang, H.-S., Pan, Z., Shi, W., Brown, B. S., Wymore, R. S., Cohen, I. S., Dixon, J. E., and McKinnon, D. (1998) Science 282, 1890-1893
20. Tinel, N., Lauritzen, I., Chouabe, C., Lazdunski, M., and Borsotto, M. (1998) FEBS Lett. 438, 171-176
21. Singh, N. A., Charlier, C., Stauffer, D., DuPont, B. R., Leach, R. J., Melis, R., Ronen, G. M., Bjerre, I., Quattlebaum, T., Murphy, J. V., McHarg, M. L., Gagnon, D., Rosales, T. O., Peiffer, A., Anderson, V. E., Leppert, M. (1998) Nat. Genet. 18, 25-29
22. Charlier, C., Singh, N. A., Ryan, S. G., Lewis, T. B., Reus, B. E., Leach, R. J., and Leppert, M. (1998) Nat. Genet. 18, 53-55
23. Brown, D. A., Adams, P. R. (1980) Nature 283, 673-676
24. Shapiro, M. S., Roche, J. P., Kaftan, E. J., Cruzblanca, H., Mackie, K., and Hille, B. (2000) J. Neurosci. 20, 1710-1721
25. Selyanko, A. A., Hadley, J. K., Wood, I. C., Abogadie, F. C., Jentsch, T. J., and Brown, D. A. (2000) J. Physiol. 522, 349-355
26. Kubisch, C., Schröder, B. C., Friedrich, T., Lütjohann, B., El-Amraoui, A., Marlin, S., Petit, C., and Jentsch, T. J. (1999) Cell 96, 437-446
27. Coucke, P. J., Van Hauwe, P., Kelley, P. M., Kunst, H., Schatteman, I., Van Velzen, D., Meyers, J., Ensink, R. J., Verstreken, M., Declau, F., Marres, H., Kastury, K., Bhasin, S., McGuirt, W. T., Smith, R. J., Cremers, C. W., Van de Heyning, P., Willems, P. J., Smith, S. D., and Van Camp, G. (1999) Hum. Mol. Genet. 8, 1321-1328
28. Villmann, C., Bull, L., and Hollmann, M. (1997) J. Neurosci. 17, 7634-7643
29. Schmitt, N., Schwarz, M., Peretz, A., Abitbol, I., Attali, B., and Pongs, O. (2000) EMBO J. 19, 332-340
30. Lerche, H., Biervert, C., Alekov, A. K., Schleithoff, L., Lindner, M., Klinger, W., Bretschneider, F., Mitrovic, N., Jurkat-Rott, K., Bode, H., Lehmann-Horn, F., and Steinlein, O. K. (1999) Ann. Neurol. 46, 305-312
31. Sanguinetti, M. C., Jurkiewicz, N. K., Scott, A., and Siegl, P. K. S. (1991) Circ. Res. 68, 77-84
32. Pusch, M., Magrassi, R., Wollnik, B., and Conti, F. (1998) Biophys. J. 75, 785-792
33. Tristani-Firouzi, M, and Sanguinetti, M. C. (1998) J. Physiol. 510, 37-45
34. Hadley, J. K., Noda, M., Selyanko, A. A., Wood, I. C., Abogadie, F. C., and Brown, D. A. (2000) Br. J. Pharmacol. 129, 413-415
35. MacKinnon, R., and Yellen, G. (1990) Science 250, 276-279
36. Suessbrich, H., Bleich, M., Ecke, D., Rizzo, M., Waldegger, S., Lang, F., Szabo, I., Lang, H.-J., Kunzelmann, K., Greger, R., and Busch, A. E. (1996) FEBS Lett. 396, 271-275
37. Busch, A. E., Busch, G. L., Ford, E., Suessbrich, H., Lang, H.-J., Greger, R., Kunzelmann, K., Attali, B., and Stühmer, W. (1997) Br. J. Pharmacol. 122, 187-189
38. Meves, H., Schwarz, J. R., and Wulfsen, I. (1999) Br. J. Pharmacol. 127, 1213-1223
39. Selyanko, A. A., Hadley, J. K., Wood, I. C., Abogadie, F. C., Delmas, P., Buckley, N. J., London, B., and Brown, D. A. (1999) J. Neurosci. 19, 7742-7756
40. Minassian, B. A., Lee, J. R., Herbrick, J. A., Huizenga, J., Soder, S., Mungall, A. J., Dunham, I., Gardner, R., Fong, C. Y., Carpenter, S., Jardim, L., Satishchandra, P., Andermann, E., Snead, O. C., Lopes-Cendes, I., Tsui, L. C., Delgado-Escueta, A. V., Rouleau, G. A., and Scherer, S. W. (1998) Nat. Genet. 20, 171-174
41. Serratosa, J. M., Gomez-Garre, P., Gallardo, M. E., Anta, B., deBernabe, D. B., Lindhout, D., Augustijn, P. B., Tassinari, C. A., Malafosse, R. M., Topcu, M., Grid, D., Dravet, C., Berkovic, S. F., and deCordoba, S. R. (1999) Hum. Mol. Genet. 8, 345-352
42. Liu, A. W., Delgado-Escueta, A. V., Gee, M. N., Serratosa, J. M., Zhang, Q. W., Alonso, M. E., Medina, M. T., Cordova, S., Zhao, H. Z., Spellman, J. M., Rubio Donnadieu, F., Ramos Peek, J., Treiman, L. J., and Sparkes, R. S. (1996) Am. J. Med. Genet. 63, 438-446