Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion

Nature Communications

Volumn 5, Issue , 2014, Pages

  Shanware, Naval P ^a   Bray, Kevin ^a   Eng, Christina H ^a   Wang, Fang ^a   Follettie, Maximillian ^a   Myers, Jeremy ^a   Fantin, Valeria R ^a   Abraham, Robert T ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; GLUTAMINASE INHIBITOR; GLUTAMINE; INTERLEUKIN 8; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN IRE1; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MTOR PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

AMINO ACID; CELL ORGANELLE; GENE EXPRESSION; INHIBITOR; METABOLISM; PROTEIN; SECRETION; SIGNALING;

AMINO ACID ANALYSIS; AMINO ACID METABOLISM; ANAPLEROSIS; ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL STRUCTURE; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CITRIC ACID CYCLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GOLGI COMPLEX; LYSOSOME; LYSOSOME MEMBRANE; METABOLISM; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; GENETICS; HUMAN; TUMOR CELL LINE;

CELL LINE, TUMOR; CITRIC ACID CYCLE; ENDOPLASMIC RETICULUM STRESS; GLUTAMINE; HUMANS; INTERLEUKIN-8; LYSOSOMES; MAP KINASE KINASE 4; MULTIPROTEIN COMPLEXES; TOR SERINE-THREONINE KINASES;

EID: 84923239727     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5900     Document Type: Article

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