메뉴 건너뛰기




Volumn 14, Issue 3, 2015, Pages 473-487

Best practice and future challenges for vaccination against porcine circovirus type 2

Author keywords

age of vaccination; immunity; maternally derived immunity; PCV2 subclinical infection; PCV2 systemic disease; pigs; porcine circovirus diseases; porcine circovirus type 2; sows; vaccine

Indexed keywords

PORCINE CIRCOVIRUS TYPE 2 VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

EID: 84923093604     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.2015.983084     Document Type: Review
Times cited : (96)

References (149)
  • 1
    • 0031950374 scopus 로고    scopus 로고
    • Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs
    • Hamel AL, Lin LL, Nayar GP. Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs. J Virol 1998;72:5262-7
    • (1998) J Virol , vol.72 , pp. 5262-5267
    • Hamel, A.L.1    Lin, L.L.2    Nayar, G.P.3
  • 2
    • 17744411241 scopus 로고    scopus 로고
    • Characterization of novel circovirus DNAs associated with wasting syndromes in pigs
    • Meehan BM, McNeilly F, Todd D, et al. Characterization of novel circovirus DNAs associated with wasting syndromes in pigs. J Gen Virol 1998;79(Pt 9):2171-9
    • (1998) J Gen Virol , vol.79 , pp. 2171-2179
    • Meehan, B.M.1    McNeilly, F.2    Todd, D.3
  • 3
    • 0002606180 scopus 로고    scopus 로고
    • Post-weaning multisystemic wasting syndrome
    • Clark EG. Post-weaning multisystemic wasting syndrome. Proc West Can Assoc Swine Pr 1996;19-20
    • (1996) Proc West Can Assoc Swine Pr , pp. 19-20
    • Clark, E.G.1
  • 4
    • 0002905464 scopus 로고    scopus 로고
    • Postweaning multisystemic wasting syndrome: Preliminary epidemiology and clinical findings
    • Harding JC. Postweaning multisystemic wasting syndrome: preliminary epidemiology and clinical findings. Proc West Can Assoc Swine Pr 1996;21
    • (1996) Proc West Can Assoc Swine Pr , vol.21
    • Harding, J.C.1
  • 5
    • 84857370179 scopus 로고    scopus 로고
    • Discovery and evolving history of two genetically related but phenotypically different viruses, porcine circoviruses 1 and 2
    • Allan G, Krakowka S, Ellis J, et al. Discovery and evolving history of two genetically related but phenotypically different viruses, porcine circoviruses 1 and 2. Virus Res 2012;164:4-9
    • (2012) Virus Res , vol.164 , pp. 4-9
    • Allan, G.1    Krakowka, S.2    Ellis, J.3
  • 6
    • 67349227125 scopus 로고    scopus 로고
    • Retrospective study on the occurrence of porcine circovirus 2 infection and associated entities in Northern Germany
    • Jacobsen B, Krueger L, Seeliger F, et al. Retrospective study on the occurrence of porcine circovirus 2 infection and associated entities in Northern Germany. Vet Microbiol 2009;138:27-33
    • (2009) Vet Microbiol , vol.138 , pp. 27-33
    • Jacobsen, B.1    Krueger, L.2    Seeliger, F.3
  • 7
    • 72849121997 scopus 로고    scopus 로고
    • Insights into the evolutionary history of an emerging livestock pathogen: Porcine circovirus 2
    • Firth C, Charleston MA, Duffy S, et al. Insights into the evolutionary history of an emerging livestock pathogen: porcine circovirus 2. J Virol 2009;83:12813-21
    • (2009) J Virol , vol.83 , pp. 12813-12821
    • Firth, C.1    Charleston, M.A.2    Duffy, S.3
  • 8
    • 84857370708 scopus 로고    scopus 로고
    • Porcine circovirus type 2 (PCV2) infections: Clinical signs, pathology and laboratory diagnosis
    • Segalés J. Porcine circovirus type 2 (PCV2) infections: clinical signs, pathology and laboratory diagnosis. Virus Res 2012; 164(1-2):10-19
    • (2012) Virus Res , vol.164 , Issue.1-2 , pp. 10-19
    • Segalés, J.1
  • 9
    • 9144250950 scopus 로고    scopus 로고
    • PMWS: Experimental model and co-infections
    • Allan GM, McNeilly F, Ellis J, et al. PMWS: experimental model and co-infections. Vet Microbiol 2004;98:165-8
    • (2004) Vet Microbiol , vol.98 , pp. 165-168
    • Allan, G.M.1    McNeilly, F.2    Ellis, J.3
  • 10
    • 0033166578 scopus 로고    scopus 로고
    • Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus
    • Allan GM, Kennedy S, McNeilly F, et al. Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus. J Comp Pathol 1999;121:1-11
    • (1999) J Comp Pathol , vol.121 , pp. 1-11
    • Allan, G.M.1    Kennedy, S.2    McNeilly, F.3
  • 11
    • 0033178282 scopus 로고    scopus 로고
    • Experimental inoculation of conventional pigs with tissue homogenates from pigs with post-weaning multisystemic wasting syndrome
    • Balasch M, Segales J, Rosell C, et al. Experimental inoculation of conventional pigs with tissue homogenates from pigs with post-weaning multisystemic wasting syndrome. J Comp Pathol 1999;121:139-48
    • (1999) J Comp Pathol , vol.121 , pp. 139-148
    • Balasch, M.1    Segales, J.2    Rosell, C.3
  • 12
    • 0032615597 scopus 로고    scopus 로고
    • Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic piglets
    • Ellis J, Krakowka S, Lairmore M, et al. Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic piglets. J Vet Diagn Invest 1999;11:3-14
    • (1999) J Vet Diagn Invest , vol.11 , pp. 3-14
    • Ellis, J.1    Krakowka, S.2    Lairmore, M.3
  • 13
    • 0016959107 scopus 로고
    • Causation and disease: The Henle-Koch postulates revisited
    • Evans AS, Street C, Haven N. Causation and disease: the Henle-Koch postulates revisited. Yale J Biol Med 1976;195:175-95
    • (1976) Yale J Biol Med , vol.195 , pp. 175-195
    • Evans, A.S.1    Street, C.2    Haven, N.3
  • 14
    • 84875386765 scopus 로고    scopus 로고
    • The blurred border between porcine circovirus type 2-systemic disease and porcine respiratory disease complex
    • Tico G, Segales J, Martínez J. The blurred border between porcine circovirus type 2-systemic disease and porcine respiratory disease complex. Vet Microbiol 2013;163:242-7
    • (2013) Vet Microbiol , vol.163 , pp. 242-247
    • Tico, G.1    Segales, J.2    Martínez, J.3
  • 15
    • 0033978176 scopus 로고    scopus 로고
    • Characterisation of PCV-2 isolates from Spain, Germany and France
    • Mankertz A, Domingo M, Folch JM, et al. Characterisation of PCV-2 isolates from Spain, Germany and France. Virus Res 2000;66:65-77
    • (2000) Virus Res , vol.66 , pp. 65-77
    • Mankertz, A.1    Domingo, M.2    Folch, J.M.3
  • 16
    • 48249089333 scopus 로고    scopus 로고
    • PCV-2 genotype definition and nomenclature
    • Segales J, Olvera A, Grau-Roma L, et al. PCV-2 genotype definition and nomenclature. Vet Rec 2008;162(26):867-8
    • (2008) Vet Rec , vol.162 , Issue.26 , pp. 867-868
    • Segales, J.1    Olvera, A.2    Grau-Roma, L.3
  • 17
    • 38849118996 scopus 로고    scopus 로고
    • Genomic analysis of PCV2 isolates from Danish archives and a current PMWS case-control study supports a shift in genotypes with time
    • Dupont K, Nielsen EO, Bækbo P, et al. Genomic analysis of PCV2 isolates from Danish archives and a current PMWS case-control study supports a shift in genotypes with time. Vet Microbiol 2008;128:56-64
    • (2008) Vet Microbiol , vol.128 , pp. 56-64
    • Dupont, K.1    Nielsen, E.O.2    Bækbo, P.3
  • 18
    • 77957894555 scopus 로고    scopus 로고
    • Porcine circovirus type 2 (PCV2): Genetic variation and newly emerging genotypes in China
    • Guo LJ, Lu YH, Wei YW, et al. Porcine circovirus type 2 (PCV2): genetic variation and newly emerging genotypes in China. Virol J 2010;7:273
    • (2010) Virol J , vol.7 , pp. 273
    • Guo, L.J.1    Lu, Y.H.2    Wei, Y.W.3
  • 19
    • 84899501772 scopus 로고    scopus 로고
    • Origin of porcine circovirus type 2 (PCV2) from swine affected by PCV2-associated diseases in Croatia
    • Novosel D, Tuboly T, Csagola A, et al. Origin of porcine circovirus type 2 (PCV2) from swine affected by PCV2-associated diseases in Croatia. Vet Rec 2014;174(17): 431
    • (2014) Vet Rec , vol.174 , Issue.17 , pp. 431
    • Novosel, D.1    Tuboly, T.2    Csagola, A.3
  • 20
    • 84878645948 scopus 로고    scopus 로고
    • The natural history of porcine circovirus type 2: From an inoffensive virus to a devastating swine disease?
    • Segales J, Kekarainen T, Cortey M. The natural history of porcine circovirus type 2: from an inoffensive virus to a devastating swine disease? Vet Microbiol 2013;165(1-2): 13-20
    • (2013) Vet Microbiol , vol.165 , Issue.1-2 , pp. 13-20
    • Segales, J.1    Kekarainen, T.2    Cortey, M.3
  • 21
    • 0036521296 scopus 로고    scopus 로고
    • Dynamics of porcine circovirus type 2 infection in a herd of pigs with postweaning multisystemic wasting syndrome
    • Rodŕiguez-Arrioja GM, Segales J, Calsamiglia M, et al. Dynamics of porcine circovirus type 2 infection in a herd of pigs with postweaning multisystemic wasting syndrome. Am J Vet Res 2002;63:354-7
    • (2002) Am J Vet Res , vol.63 , pp. 354-357
    • Rodŕiguez-Arrioja, G.M.1    Segales, J.2    Calsamiglia, M.3
  • 22
    • 0038005380 scopus 로고    scopus 로고
    • Comparative serologic and virologic study of commercial swine herds with and without postweaning multisystemic wasting syndrome
    • Larochelle R, Magar R, D'Allaire S. Comparative serologic and virologic study of commercial swine herds with and without postweaning multisystemic wasting syndrome. Can J Vet Res 2003;67:114-20
    • (2003) Can J Vet Res , vol.67 , pp. 114-120
    • Larochelle, R.1    Magar, R.2    D'Allaire, S.3
  • 23
    • 0346656700 scopus 로고    scopus 로고
    • Use of a polymerase chain reaction assay and an ELISA to monitor porcine circovirus type 2 infection in pigs from farms with and without postweaning multisystemic wasting syndrome
    • Sibila M, Calsamiglia M, Segales J, et al. Use of a polymerase chain reaction assay and an ELISA to monitor porcine circovirus type 2 infection in pigs from farms with and without postweaning multisystemic wasting syndrome. Am J Vet Res 2004;65: 88-92
    • (2004) Am J Vet Res , vol.65 , pp. 88-92
    • Sibila, M.1    Calsamiglia, M.2    Segales, J.3
  • 24
    • 34250796905 scopus 로고    scopus 로고
    • The levels of PCV2 specific antibodies and viremia in pigs
    • Carasova P, Celer V, Takacova K, et al. The levels of PCV2 specific antibodies and viremia in pigs. Res Vet Sci 2007;83:274-8
    • (2007) Res Vet Sci , vol.83 , pp. 274-278
    • Carasova, P.1    Celer, V.2    Takacova, K.3
  • 25
    • 61849151905 scopus 로고    scopus 로고
    • Infection, excretion and seroconversion dynamics of porcine circovirus type 2 (PCV2) in pigs from post-weaning multisystemic wasting syndrome (PMWS) affected farms in Spain and Denmark
    • Grau-Roma L, Hjulsager CK, Sibila M, et al. Infection, excretion and seroconversion dynamics of porcine circovirus type 2 (PCV2) in pigs from post-weaning multisystemic wasting syndrome (PMWS) affected farms in Spain and Denmark. Vet Microbiol 2009;135:272-82
    • (2009) Vet Microbiol , vol.135 , pp. 272-282
    • Grau-Roma, L.1    Hjulsager, C.K.2    Sibila, M.3
  • 26
    • 33646258971 scopus 로고    scopus 로고
    • Correlation between the presence of neutralizing antibodies against porcine circovirus 2 (PCV2) and protection against replication of the virus and development of PCV2-associated disease
    • Meerts P, Misinzo G, Lefebvre D, et al. Correlation between the presence of neutralizing antibodies against porcine circovirus 2 (PCV2) and protection against replication of the virus and development of PCV2-associated disease. BMC Vet Res 2006;2:6
    • (2006) BMC Vet Res , vol.2 , pp. 6
    • Meerts, P.1    Misinzo, G.2    Lefebvre, D.3
  • 27
    • 0035350580 scopus 로고    scopus 로고
    • Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrum-deprived piglets with type 2 porcine circovirus
    • Bolin SR, Stoffregen WC, Nayar GP, et al. Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrum-deprived piglets with type 2 porcine circovirus. J Vet Diagn Invest 2001;13:185-94
    • (2001) J Vet Diagn Invest , vol.13 , pp. 185-194
    • Bolin, S.R.1    Stoffregen, W.C.2    Nayar, G.P.3
  • 28
    • 0037159123 scopus 로고    scopus 로고
    • Reproduction of postweaning multisystemic wasting syndrome (PMWS) in immunostimulated and non-immunostimulated 3-week-old piglets experimentally infected with porcine circovirus type 2 (PCV2)
    • Ladekjaer-Mikkelsen AS, Nielsen J, Stadejek T, et al. Reproduction of postweaning multisystemic wasting syndrome (PMWS) in immunostimulated and non-immunostimulated 3-week-old piglets experimentally infected with porcine circovirus type 2 (PCV2). Vet Microbiol 2002;89(2-3):97-114
    • (2002) Vet Microbiol , vol.89 , Issue.2-3 , pp. 97-114
    • Ladekjaer-Mikkelsen, A.S.1    Nielsen, J.2    Stadejek, T.3
  • 29
    • 0036118237 scopus 로고    scopus 로고
    • Experimental inoculation of conventional pigs with porcine reproductive and respiratory syndrome virus and porcine circovirus 2
    • Rovira A, Balasch M, Segalés J, et al. Experimental inoculation of conventional pigs with porcine reproductive and respiratory syndrome virus and porcine circovirus 2. J Virol 2002;76:3232-9
    • (2002) J Virol , vol.76 , pp. 3232-3239
    • Rovira, A.1    Balasch, M.2    Segalés, J.3
  • 30
    • 0037672914 scopus 로고    scopus 로고
    • Experimental reproduction of postweaning multisystemic wasting syndrome in cesarean-derived, colostrum-deprived piglets inoculated with porcine circovirus type 2 (PCV2): Investigation of quantitative PCV2 distribution and antibody responses
    • Okuda Y, Ono M, Yazawa S, et al. Experimental reproduction of postweaning multisystemic wasting syndrome in cesarean-derived, colostrum-deprived piglets inoculated with porcine circovirus type 2 (PCV2): investigation of quantitative PCV2 distribution and antibody responses. J Vet Diagn Invest 2003;15:107-14
    • (2003) J Vet Diagn Invest , vol.15 , pp. 107-114
    • Okuda, Y.1    Ono, M.2    Yazawa, S.3
  • 31
    • 32944472730 scopus 로고    scopus 로고
    • Detection of Porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn
    • McIntosh Ka, Harding JCS, Ellis Ja, et al. Detection of Porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn. Can J Vet Res 2006;70(1):58-61
    • (2006) Can J Vet Res , vol.70 , Issue.1 , pp. 58-61
    • Ka, M.1    Jcs, H.2    Ja, E.3
  • 32
    • 35348832244 scopus 로고    scopus 로고
    • Detection of neutralizing antibodies in postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs
    • Fort M, Olvera A, Sibila M, et al. Detection of neutralizing antibodies in postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs. Vet Microbiol 2007;125:244-55
    • (2007) Vet Microbiol , vol.125 , pp. 244-255
    • Fort, M.1    Olvera, A.2    Sibila, M.3
  • 33
    • 0033916522 scopus 로고    scopus 로고
    • Characterization of immune response of young pigs to porcine circovirus type 2 infection
    • Pogranichnyy RM, Yoon KJ, Harms PA, et al. Characterization of immune response of young pigs to porcine circovirus type 2 infection. Viral Immunol 2000;13: 143-53
    • (2000) Viral Immunol , vol.13 , pp. 143-153
    • Pogranichnyy, R.M.1    Yoon, K.J.2    Harms, P.A.3
  • 34
    • 0036126108 scopus 로고    scopus 로고
    • Changes in CD4+, CD8+, CD4+ CD8+, and immunoglobulin M-positive peripheral blood mononuclear cells of postweaning multisystemic wasting syndrome-affected pigs and age-matched uninfected wasted and healthy pigs correlate with lesions and porcine circovirus
    • Darwich L, Segalés J, Domingo M, et al. Changes in CD4+, CD8+, CD4+ CD8+, and immunoglobulin M-positive peripheral blood mononuclear cells of postweaning multisystemic wasting syndrome-affected pigs and age-matched uninfected wasted and healthy pigs correlate with lesions and porcine circovirus. Clin Diagn Lab Immunol 2002;9(2):236-42
    • (2002) Clin Diagn Lab Immunol , vol.9 , Issue.2 , pp. 236-242
    • Darwich, L.1    Segalés, J.2    Domingo, M.3
  • 35
    • 0037828667 scopus 로고    scopus 로고
    • Association of lymphopenia with porcine circovirus type 2 induced postweaning multisystemic wasting syndrome (PMWS)
    • Nielsen J, Vincent IE, Bøtner A, et al. Association of lymphopenia with porcine circovirus type 2 induced postweaning multisystemic wasting syndrome (PMWS). Vet Immunol Immunopathol 2003;92: 97-111
    • (2003) Vet Immunol Immunopathol , vol.92 , pp. 97-111
    • Nielsen, J.1    Vincent, I.E.2    Bøtner, A.3
  • 36
    • 0036453544 scopus 로고    scopus 로고
    • Immunologic features of porcine circovirus type 2 infection
    • Krakowka S, Ellis JA, McNeilly F, et al. Immunologic features of porcine circovirus type 2 infection. Viral Immunol 2002; 15(4):567-82
    • (2002) Viral Immunol , vol.15 , Issue.4 , pp. 567-582
    • Krakowka, S.1    Ellis, J.A.2    McNeilly, F.3
  • 37
    • 0142151174 scopus 로고    scopus 로고
    • Effects of dexamethasone on the pathogenesis of porcine circovirus type 2 infection in piglets
    • Kawashima K, Tsunemitsu H, Horino R, et al. Effects of dexamethasone on the pathogenesis of porcine circovirus type 2 infection in piglets. J Comp Pathol 2003;129:294-302
    • (2003) J Comp Pathol , vol.129 , pp. 294-302
    • Kawashima, K.1    Tsunemitsu, H.2    Horino, R.3
  • 38
    • 23344453938 scopus 로고    scopus 로고
    • Correlation between type of adaptive immune response against porcine circovirus type 2 and level of virus replication
    • Meerts P, Van Gucht S, Cox E, et al. Correlation between type of adaptive immune response against porcine circovirus type 2 and level of virus replication. Viral Immunol 2005;18:333-41
    • (2005) Viral Immunol , vol.18 , pp. 333-341
    • Meerts, P.1    Van Gucht, S.2    Cox, E.3
  • 39
    • 62549147496 scopus 로고    scopus 로고
    • Development of cell-mediated immunity to porcine circovirus type 2 (PCV2) in caesarean-derived, colostrum-deprived piglets
    • Fort M, Fernandes LT, Nofrarias M, et al. Development of cell-mediated immunity to porcine circovirus type 2 (PCV2) in caesarean-derived, colostrum-deprived piglets. Vet Immunol Immunopathol 2009;129:101-7
    • (2009) Vet Immunol Immunopathol , vol.129 , pp. 101-107
    • Fort, M.1    Fernandes, L.T.2    Nofrarias, M.3
  • 40
    • 67349110424 scopus 로고    scopus 로고
    • One dose of a porcine circovirus 2 (PCV2) sub-unit vaccine administered to 3-week-old conventional piglets elicits cell-mediated immunity and significantly reduces PCV2 viremia in an experimental model
    • Fort M, Sibila M, Pérez-Martín E, et al. One dose of a porcine circovirus 2 (PCV2) sub-unit vaccine administered to 3-week-old conventional piglets elicits cell-mediated immunity and significantly reduces PCV2 viremia in an experimental model. Vaccine 2009;27:4031-7
    • (2009) Vaccine , vol.27 , pp. 4031-4037
    • Fort, M.1    Sibila, M.2    Pérez-Martín, E.3
  • 41
    • 84867334554 scopus 로고    scopus 로고
    • Evaluation of cell-mediated immune responses against porcine circovirus type 2 (PCV2) Cap and Rep proteins after vaccination with a commercial PCV2 sub-unit vaccine
    • Fort M, Sibila M, Nofraŕias M, et al. Evaluation of cell-mediated immune responses against porcine circovirus type 2 (PCV2) Cap and Rep proteins after vaccination with a commercial PCV2 sub-unit vaccine. Vet Immunol Immunopathol 2012;150:128-32
    • (2012) Vet Immunol Immunopathol , vol.150 , pp. 128-132
    • Fort, M.1    Sibila, M.2    Nofraŕias, M.3
  • 42
    • 77449104981 scopus 로고    scopus 로고
    • Cellular adaptive immune response against porcine circovirus type 2 in subclinically infected pigs
    • Steiner E, Balmelli C, Gerber H, et al. Cellular adaptive immune response against porcine circovirus type 2 in subclinically infected pigs. BMC Vet Res 2009;5:45
    • (2009) BMC Vet Res , vol.5 , pp. 45
    • Steiner, E.1    Balmelli, C.2    Gerber, H.3
  • 43
    • 79953065578 scopus 로고    scopus 로고
    • One dose of a porcine circovirus 2 subunit vaccine induces humoral and cell-mediated immunity and protects against porcine circovirus-associated disease under field conditions
    • Martelli P, Ferrari L, Morganti M, et al. One dose of a porcine circovirus 2 subunit vaccine induces humoral and cell-mediated immunity and protects against porcine circovirus-associated disease under field conditions. Vet Microbiol 2011;149(3-4): 339-51
    • (2011) Vet Microbiol , vol.149 , Issue.3-4 , pp. 339-351
    • Martelli, P.1    Ferrari, L.2    Morganti, M.3
  • 44
    • 84899637342 scopus 로고    scopus 로고
    • Memory T cell proliferative responses and IFN-g productivity sustain long-lasting efficacy of a Cap-based PCV2 vaccine upon PCV2 natural infection and associated disease
    • Ferrari L, Borghetti P, De Angelis E, et al. Memory T cell proliferative responses and IFN-g productivity sustain long-lasting efficacy of a Cap-based PCV2 vaccine upon PCV2 natural infection and associated disease. Vet Res 2014;45:44
    • (2014) Vet Res , vol.45 , pp. 44
    • Ferrari, L.1    Borghetti, P.2    De Angelis, E.3
  • 45
    • 84857368907 scopus 로고    scopus 로고
    • Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)
    • Beach NM, Meng XJ. Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2). Virus Res 2012; 164(1-2):33-42
    • (2012) Virus Res , vol.164 , Issue.1-2 , pp. 33-42
    • Beach, N.M.1    Meng, X.J.2
  • 46
    • 84857058112 scopus 로고    scopus 로고
    • HIV vaccine development at the turn of the 21st century
    • Girard MP, Plotkin SA. HIV vaccine development at the turn of the 21st century. Curr Opin HIV AIDS 2012;7:4-9
    • (2012) Curr Opin HIV AIDS , vol.7 , pp. 4-9
    • Girard, M.P.1    Plotkin, S.A.2
  • 47
    • 79953029879 scopus 로고    scopus 로고
    • DNA immunization of pigs with foot-and-mouth disease virus minigenes: From partial protection to disease exacerbation
    • Ganges L, Borrego B, Fernandez-Pacheco P, et al. DNA immunization of pigs with foot-and-mouth disease virus minigenes: from partial protection to disease exacerbation. Virus Res 2011;157:121-5
    • (2011) Virus Res , vol.157 , pp. 121-125
    • Ganges, L.1    Borrego, B.2    Fernandez-Pacheco, P.3
  • 48
    • 38749115314 scopus 로고    scopus 로고
    • Efficacy of experimental inactivated PCV2 vaccines for preventing PMWS in CDCD pigs
    • Pogranichniy RM, Yoon K-J, Yaeger MJ, et al. Efficacy of experimental inactivated PCV2 vaccines for preventing PMWS in CDCD pigs. Proc Annu Meet Am Assoc Swine Vet 2004;35:443-4
    • (2004) Proc Annu Meet Am Assoc Swine Vet , vol.35 , pp. 443-444
    • Pogranichniy, R.M.1    Yoon, K.-J.2    Yaeger, M.J.3
  • 49
    • 84869207246 scopus 로고    scopus 로고
    • Efficacy of single dose of an inactivated porcine circovirus type 2 (PCV2) whole-virus vaccine with oil adjuvant in piglets
    • Yang K, Li W, Niu H, et al. Efficacy of single dose of an inactivated porcine circovirus type 2 (PCV2) whole-virus vaccine with oil adjuvant in piglets. Acta Vet Scand 2012;54:67
    • (2012) Acta Vet Scand , vol.54 , pp. 67
    • Yang, K.1    Li, W.2    Niu, H.3
  • 52
    • 0142199970 scopus 로고    scopus 로고
    • Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins
    • Blanchard P, Mahe D, Cariolet R, et al. Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins. Vaccine 2003;21:4565-75
    • (2003) Vaccine , vol.21 , pp. 4565-4575
    • Blanchard, P.1    Mahe, D.2    Cariolet, R.3
  • 53
    • 56249098617 scopus 로고    scopus 로고
    • Development of two Trichoplusia ni larvae-derived ELISAs for the detection of antibodies against replicase and capsid proteins of porcine circovirus type 2 in domestic pigs
    • Perez-Martin E, Grau-Roma L, Argilaguet JM, et al. Development of two Trichoplusia ni larvae-derived ELISAs for the detection of antibodies against replicase and capsid proteins of porcine circovirus type 2 in domestic pigs. J Virol Methods 2008; 154(1-2): 167-74
    • (2008) J Virol Methods , vol.154 , Issue.1-2 , pp. 167-174
    • Perez-Martin, E.1    Grau-Roma, L.2    Argilaguet, J.M.3
  • 54
    • 23044502459 scopus 로고    scopus 로고
    • Immunogenicity of a recombinant pseudorabies virus expressing ORF1-ORF2 fusion protein of porcine circovirus type 2
    • Ju C, Fan H, Tan Y, et al. Immunogenicity of a recombinant pseudorabies virus expressing ORF1-ORF2 fusion protein of porcine circovirus type 2. Vet Microbiol 2005;109:179-90
    • (2005) Vet Microbiol , vol.109 , pp. 179-190
    • Ju, C.1    Fan, H.2    Tan, Y.3
  • 55
    • 33947187161 scopus 로고    scopus 로고
    • Protection of pigs against post-weaning multisystemic wasting syndrome by a recombinant adenovirus expressing the capsid protein of porcine circovirus type 2
    • Wang X, Jiang P, Li Y, et al. Protection of pigs against post-weaning multisystemic wasting syndrome by a recombinant adenovirus expressing the capsid protein of porcine circovirus type 2. Vet Microbiol 2007;121:215-24
    • (2007) Vet Microbiol , vol.121 , pp. 215-224
    • Wang, X.1    Jiang, P.2    Li, Y.3
  • 56
    • 42649104739 scopus 로고    scopus 로고
    • Construction and immunogenicity of recombinant pseudotype baculovirus expressing the capsid protein of porcine circovirus type 2 in mice
    • Fan H, Pan Y, Fang L, et al. Construction and immunogenicity of recombinant pseudotype baculovirus expressing the capsid protein of porcine circovirus type 2 in mice. J Virol Methods 2008;150:21-6
    • (2008) J Virol Methods , vol.150 , pp. 21-26
    • Fan, H.1    Pan, Y.2    Fang, L.3
  • 57
    • 42649133821 scopus 로고    scopus 로고
    • Expression of the capsid protein of porcine circovirus type 2 in Lactococcus lactis for oral vaccination
    • Wang K, Huang L, Kong J, et al. Expression of the capsid protein of porcine circovirus type 2 in Lactococcus lactis for oral vaccination. J Virol Methods 2008;150: 1-6
    • (2008) J Virol Methods , vol.150 , pp. 1-6
    • Wang, K.1    Huang, L.2    Kong, J.3
  • 58
    • 65949113396 scopus 로고    scopus 로고
    • Protective immunity against porcine circovirus 2 in mice induced by a gene-based combination vaccination
    • Aravindaram K, Kuo TY, Lan CW, et al. Protective immunity against porcine circovirus 2 in mice induced by a gene-based combination vaccination. J Gene Med 2009;11:288-301
    • (2009) J Gene Med , vol.11 , pp. 288-301
    • Aravindaram, K.1    Kuo, T.Y.2    Lan, C.W.3
  • 59
    • 69749101697 scopus 로고    scopus 로고
    • The optimized capsid gene of porcine circovirus type 2 expressed in yeast forms virus-like particles and elicits antibody responses in mice fed with recombinant yeast extracts
    • Bucarey SA, Noriega J, Reyes P, et al. The optimized capsid gene of porcine circovirus type 2 expressed in yeast forms virus-like particles and elicits antibody responses in mice fed with recombinant yeast extracts. Vaccine 2009;27:5781-90
    • (2009) Vaccine , vol.27 , pp. 5781-5790
    • Bucarey, S.A.1    Noriega, J.2    Reyes, P.3
  • 60
    • 77049128217 scopus 로고    scopus 로고
    • Immunity conferred by an experimental vaccine based on the recombinant PCV2 Cap protein expressed in Trichoplusia ni-larvae
    • Pérez-Martín E, Gómez-Sebastián S, Argilaguet JM, et al. Immunity conferred by an experimental vaccine based on the recombinant PCV2 Cap protein expressed in Trichoplusia ni-larvae. Vaccine 2010;28: 2340-9
    • (2010) Vaccine , vol.28 , pp. 2340-2349
    • Pérez-Martín, E.1    Gómez-Sebastián, S.2    Argilaguet, J.M.3
  • 61
    • 84865729567 scopus 로고    scopus 로고
    • Construction and immunogenicity of recombinant swinepox virus expressing capsid protein of PCV2
    • Lin HX, Ma Z, Fan HJ, Lu CP. Construction and immunogenicity of recombinant swinepox virus expressing capsid protein of PCV2. Vaccine 2012;30: 6307-13
    • (2012) Vaccine , vol.30 , pp. 6307-6313
    • Lin, H.X.1    Ma, Z.2    Fan, H.J.3    Lu, C.P.4
  • 62
    • 84871446833 scopus 로고    scopus 로고
    • A cucumber mosaic virus based expression system for the production of porcine circovirus specific vaccines
    • Gellért A, Salánki K, Tombácz K, et al. A cucumber mosaic virus based expression system for the production of porcine circovirus specific vaccines. PLoS One 2012; 7(12):e52688
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e52688
    • Gellért, A.1    Salánki, K.2    Tombácz, K.3
  • 63
    • 84863724358 scopus 로고    scopus 로고
    • Genetic diversity of pigeon circovirus in Hungary
    • Cságola A, Lorincz M, Tombácz K, et al. Genetic diversity of pigeon circovirus in Hungary. Virus Genes 2012;44:75-9
    • (2012) Virus Genes , vol.44 , pp. 75-79
    • Cságola, A.1    Lorincz, M.2    Tombácz, K.3
  • 64
    • 84888158534 scopus 로고    scopus 로고
    • Oral immunogenicity of a plant virus vector based porcine circovirus antigen
    • Tombácz K, Gellért A, Salánki K, et al. Oral immunogenicity of a plant virus vector based porcine circovirus antigen. Acta Vet Hung 2013;61(4):547-52
    • (2013) Acta Vet Hung , vol.61 , Issue.4 , pp. 547-552
    • Tombácz, K.1    Gellért, A.2    Salánki, K.3
  • 65
    • 84907018982 scopus 로고    scopus 로고
    • Enhancing mucosal immunity in mice induced by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein formulated with CpG ODN
    • Chang HT, He XY, Chen L, et al. Enhancing mucosal immunity in mice induced by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein formulated with CpG ODN. J Vet Sci 2014;15(3):399-407
    • (2014) J Vet Sci , vol.15 , Issue.3 , pp. 399-407
    • Chang, H.T.1    He, X.Y.2    Chen, L.3
  • 66
    • 84899628880 scopus 로고    scopus 로고
    • The preparation of porcine circovirus type 2 (PCV2) virus-like particles using a recombinant pseudorabies virus and its application to vaccine development
    • Chi J-N, Wu C-Y, Chien M-S, et al. The preparation of porcine circovirus type 2 (PCV2) virus-like particles using a recombinant pseudorabies virus and its application to vaccine development. J Biotechnol 2014;181:12-19
    • (2014) J Biotechnol , vol.181 , pp. 12-19
    • Chi, J.-N.1    Wu, C.-Y.2    Chien, M.-S.3
  • 67
    • 84923117131 scopus 로고    scopus 로고
    • Secretory expression of porcine circovirus type 2 capsid protein in Pichia pastoris
    • Silva JG, Coimbra EC, Jesus ALS, et al. Secretory expression of porcine circovirus type 2 capsid protein in Pichia pastoris. J Virol Methods 2014;207C:226-31
    • (2014) J Virol Methods , vol.207 C , pp. 226-231
    • Silva, J.G.1    Coimbra, E.C.2    Als, J.3
  • 68
    • 50549090178 scopus 로고    scopus 로고
    • Protective immunity against porcine circovirus 2 by vaccination with ORF2-based DNA and subunit vaccines in mice
    • Shen H-G, Zhou J-Y, Huang Z-Y, et al. Protective immunity against porcine circovirus 2 by vaccination with ORF2-based DNA and subunit vaccines in mice. J Gen Virol 2008;89:1857-65
    • (2008) J Gen Virol , vol.89 , pp. 1857-1865
    • Shen, H.-G.1    Zhou, J.-Y.2    Huang, Z.-Y.3
  • 69
    • 1842509172 scopus 로고    scopus 로고
    • Immunisation against PCV2 structural protein by DNA vaccination of mice
    • Kamstrup S, Barfoed AM, Frimann TH, et al. Immunisation against PCV2 structural protein by DNA vaccination of mice. Vaccine 2004;22:1358-61
    • (2004) Vaccine , vol.22 , pp. 1358-1361
    • Kamstrup, S.1    Barfoed, A.M.2    Frimann, T.H.3
  • 70
    • 51049099134 scopus 로고    scopus 로고
    • Systemic cytokine profiles of mice vaccinated with naked DNAs encoding six open reading frame antigens of porcine circovirus type 2 (PCV2)
    • An DJ, Song DS, Park BK. Systemic cytokine profiles of mice vaccinated with naked DNAs encoding six open reading frame antigens of porcine circovirus type 2 (PCV2). Res Vet Sci 2008;85:503-9
    • (2008) Res Vet Sci , vol.85 , pp. 503-509
    • An, D.J.1    Song, D.S.2    Park, B.K.3
  • 71
    • 79957555355 scopus 로고    scopus 로고
    • Co-expression of ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in mice
    • Fu F, Li X, Lang Y, et al. Co-expression of ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in mice. Virol J 2011;8:264
    • (2011) Virol J , vol.8 , pp. 264
    • Fu, F.1    Li, X.2    Lang, Y.3
  • 72
    • 84903887424 scopus 로고    scopus 로고
    • Protective immunity conferred by porcine circovirus 2 ORF2-based DNA vaccine in mice
    • Sylla S, Cong Y-L, Sun Y-X, et al. Protective immunity conferred by porcine circovirus 2 ORF2-based DNA vaccine in mice. Microbiol Immunol 2014;58(7): 398-408
    • (2014) Microbiol Immunol , vol.58 , Issue.7 , pp. 398-408
    • Sylla, S.1    Cong, Y.-L.2    Sun, Y.-X.3
  • 73
    • 0141788497 scopus 로고    scopus 로고
    • Immunogenicity and pathogenicity of chimeric infectious DNA clones of pathogenic porcine circovirus type 2 (PCV2) and nonpathogenic PCV1 in weanling pigs
    • Fenaux M, Opriessnig T, Halbur PG, et al. Immunogenicity and pathogenicity of chimeric infectious DNA clones of pathogenic porcine circovirus type 2 (PCV2) and nonpathogenic PCV1 in weanling pigs. J Virol 2003;77:11232-43
    • (2003) J Virol , vol.77 , pp. 11232-11243
    • Fenaux, M.1    Opriessnig, T.2    Halbur, P.G.3
  • 74
    • 2642552185 scopus 로고    scopus 로고
    • A Chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs
    • Fenaux M, Opriessnig T, Halbur PG, et al. A Chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs. J Virol 2004; 78(12):6297-303
    • (2004) J Virol , vol.78 , Issue.12 , pp. 6297-6303
    • Fenaux, M.1    Opriessnig, T.2    Halbur, P.G.3
  • 75
    • 78649696450 scopus 로고    scopus 로고
    • Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtype
    • Beach NM, Ramamoorthy S, Opriessnig T, et al. Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtype. Vaccine 2010; 29(2):221-32
    • (2010) Vaccine , vol.29 , Issue.2 , pp. 221-232
    • Beach, N.M.1    Ramamoorthy, S.2    Opriessnig, T.3
  • 76
    • 84892554630 scopus 로고    scopus 로고
    • A live-attenuated and an inactivated chimeric porcine circovirus (PCV)1-2 vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age
    • Hemann M, Beach NM, Meng X-J, et al. A live-attenuated and an inactivated chimeric porcine circovirus (PCV)1-2 vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age. Can J Vet Res 2014;78(1):8-16
    • (2014) Can J Vet Res , vol.78 , Issue.1 , pp. 8-16
    • Hemann, M.1    Beach, N.M.2    Meng, X.-J.3
  • 77
    • 79953080746 scopus 로고    scopus 로고
    • A candidate inactivated chimeric vaccine PCV1-2 constructed based on PCV1 and PCV2 isolates originating in China and its evaluation in conventional pigs in regard to protective efficacy against PCV2 infection
    • Xujie L, Xiaobo W, Yi S, et al. A candidate inactivated chimeric vaccine PCV1-2 constructed based on PCV1 and PCV2 isolates originating in China and its evaluation in conventional pigs in regard to protective efficacy against PCV2 infection. Microbiol Immunol 2011;55(4):254-66
    • (2011) Microbiol Immunol , vol.55 , Issue.4 , pp. 254-266
    • Xujie, L.1    Xiaobo, W.2    Yi, S.3
  • 78
    • 84857373479 scopus 로고    scopus 로고
    • Porcine circovirus type 2 and its associated diseases in Korea
    • Chae C. Porcine circovirus type 2 and its associated diseases in Korea. Virus Res 2012;164:107-13
    • (2012) Virus Res , vol.164 , pp. 107-113
    • Chae, C.1
  • 79
    • 84901496396 scopus 로고    scopus 로고
    • Porcine circovirus type 2 in China: An update on and insights to its prevalence and control
    • Zhai S-L, Chen S-N, Xu Z-H, et al. Porcine circovirus type 2 in China: an update on and insights to its prevalence and control. Virol J 2014;11:88
    • (2014) Virol J , vol.11 , pp. 88
    • Zhai, S.-L.1    Chen, S.-N.2    Xu, Z.-H.3
  • 80
    • 78650190504 scopus 로고    scopus 로고
    • Efficacy of different protocols of vaccination against porcine circovirus type 2 (PCV2) in a farm affected by postweaning multisystemic wasting syndrome (PMWS)
    • Pejsak Z, Podgórska K, Truszczyński M, et al. Efficacy of different protocols of vaccination against porcine circovirus type 2 (PCV2) in a farm affected by postweaning multisystemic wasting syndrome (PMWS). Comp Immunol Microbiol Infect Dis 2010; 33(6):e1-5
    • (2010) Comp Immunol Microbiol Infect Dis , vol.33 , Issue.6 , pp. e1-5
    • Pejsak, Z.1    Podgórska, K.2    Truszczyński, M.3
  • 81
    • 77952094695 scopus 로고    scopus 로고
    • Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination
    • Opriessnig T, Patterson AR, Madson DM, et al. Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination. Vet Microbiol 2010;142: 177-83
    • (2010) Vet Microbiol , vol.142 , pp. 177-183
    • Opriessnig, T.1    Patterson, A.R.2    Madson, D.M.3
  • 82
    • 84868135671 scopus 로고    scopus 로고
    • Vaccination of sows reduces the prevalence of PCV-2 viraemia in their piglets under field conditions
    • Kurmann J, Sydler T, Brugnera E, et al
    • O'Neill KC, Hemann M, Gimenez-Lirola LG, et al. Vaccination of sows reduces the prevalence of PCV-2 viraemia in their piglets under field conditions. Vet Rec 2012;171:425-83. Kurmann J, Sydler T, Brugnera E, et al.
    • (2012) Vet Rec , vol.171 , pp. 425-83
    • O'Neill, K.C.1    Hemann, M.2    Gimenez-Lirola, L.G.3
  • 83
    • 80053451322 scopus 로고    scopus 로고
    • Vaccination of dams increases antibody titer and improves growth parameters in finisher pigs subclinically infected with porcine circovirus type 2
    • Vaccination of dams increases antibody titer and improves growth parameters in finisher pigs subclinically infected with porcine circovirus type 2. Clin Vaccine Immunol 2011;18(10):1644-9
    • (2011) Clin Vaccine Immunol , vol.18 , Issue.10 , pp. 1644-1649
  • 84
    • 84855592091 scopus 로고    scopus 로고
    • Fetal infections and antibody profiles in pigs naturally infected with porcine circovirus type 2 (PCV2)
    • Gerber PF, Garrocho FM, Lana AM, et al. Fetal infections and antibody profiles in pigs naturally infected with porcine circovirus type 2 (PCV2). Can J Vet Res 2012;76: 38-44
    • (2012) Can J Vet Res , vol.76 , pp. 38-44
    • Gerber, P.F.1    Garrocho, F.M.2    Lana, A.M.3
  • 85
    • 79953781030 scopus 로고    scopus 로고
    • Serum antibodies and shedding of infectious porcine circovirus 2 into colostrum and milk of vaccinated and unvaccinated naturally infected sows
    • Gerber PF, Garrocho FM, Lana AMQ, et al. Serum antibodies and shedding of infectious porcine circovirus 2 into colostrum and milk of vaccinated and unvaccinated naturally infected sows. Vet J 2011;188:240-2
    • (2011) Vet J , vol.188 , pp. 240-242
    • Gerber, P.F.1    Garrocho, F.M.2    Amq, L.3
  • 86
    • 84869869710 scopus 로고    scopus 로고
    • Effect of sow and piglet porcine circovirus type 2 (PCV2) vaccination on piglet mortality, viraemia, antibody titre and production parameters
    • Fraile L, Sibila M, Nofraŕias M, et al. Effect of sow and piglet porcine circovirus type 2 (PCV2) vaccination on piglet mortality, viraemia, antibody titre and production parameters. Vet Microbiol 2012;161:229-34
    • (2012) Vet Microbiol , vol.161 , pp. 229-234
    • Fraile, L.1    Sibila, M.2    Nofraŕias, M.3
  • 87
    • 79959841548 scopus 로고    scopus 로고
    • Ear necrosis reduction in pigs after vaccination against PCV2
    • Pejsak Z, Markowska-Daniel I, Pomorska-Mól M, et al. Ear necrosis reduction in pigs after vaccination against PCV2. Res Vet Sci 2011;91:125-8
    • (2011) Res Vet Sci , vol.91 , pp. 125-128
    • Pejsak, Z.1    Markowska-Daniel, I.2    Pomorska-Mól, M.3
  • 88
    • 84859376159 scopus 로고    scopus 로고
    • Influence of long-term vaccination of a breeding herd of pigs against PCV2 on reproductive parameters
    • Pejsak Z, Kusior G, Pomorska-Mól M, et al. Influence of long-term vaccination of a breeding herd of pigs against PCV2 on reproductive parameters. Pol J Vet Sci 2012;15(1):37-42
    • (2012) Pol J Vet Sci , vol.15 , Issue.1 , pp. 37-42
    • Pejsak, Z.1    Kusior, G.2    Pomorska-Mól, M.3
  • 89
    • 84923090862 scopus 로고    scopus 로고
    • PCV2 and reproductive performance: Facts and figures for the disbelievers
    • Villa T. PCV2 and reproductive performance: facts and figures for the disbelievers. In: merial Symposium. 18th IPVS; Durban, South Africa; 2008
    • (2008) Merial Symposium. 18th IPVS; Durban South Africa
    • Villa, T.1
  • 91
    • 67249126643 scopus 로고    scopus 로고
    • Effect of porcine circovirus type 2 (PCV2) vaccination of the dam on PCV2 replication in utero
    • Madson DM, Patterson AR, Ramamoorthy S, et al. Effect of porcine circovirus type 2 (PCV2) vaccination of the dam on PCV2 replication in utero. Clin Vaccine Immunol 2009;16:830-4
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 830-834
    • Madson, D.M.1    Patterson, A.R.2    Ramamoorthy, S.3
  • 92
    • 0034461757 scopus 로고    scopus 로고
    • PCR detection and evidence of shedding of porcine circovirus type 2 in boar semen
    • Larochelle R, Bielanski A, Müller P, et al. PCR detection and evidence of shedding of porcine circovirus type 2 in boar semen. J Clin Microbiol 2000;38:4629-32
    • (2000) J Clin Microbiol , vol.38 , pp. 4629-4632
    • Larochelle, R.1    Bielanski, A.2    Müller, P.3
  • 93
    • 79960150113 scopus 로고    scopus 로고
    • Effects of an inactivated porcine circovirus type 2 (PCV2) vaccine on PCV2 virus shedding in semen from experimentally infected boars
    • Seo HW, Han K, Kim D, et al. Effects of an inactivated porcine circovirus type 2 (PCV2) vaccine on PCV2 virus shedding in semen from experimentally infected boars. Clin Vaccine Immunol 2011;18:1091-6
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 1091-1096
    • Seo, H.W.1    Han, K.2    Kim, D.3
  • 94
    • 58249119556 scopus 로고    scopus 로고
    • Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars
    • Madson DM, Ramamoorthy S, Kuster C, et al. Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars. Vet Res 2009; 40(1):10
    • (2009) Vet Res , vol.40 , Issue.1 , pp. 10
    • Madson, D.M.1    Ramamoorthy, S.2    Kuster, C.3
  • 95
    • 84875865067 scopus 로고    scopus 로고
    • Comparison of three commercial one-dose porcine circovirus type 2 (PCV2) vaccines on PCV2 shedding in semen from experimentally infected boars
    • Seo HW, Han K, Oh Y, et al. Comparison of three commercial one-dose porcine circovirus type 2 (PCV2) vaccines on PCV2 shedding in semen from experimentally infected boars. Vet Microbiol 2013;164:145-9
    • (2013) Vet Microbiol , vol.164 , pp. 145-149
    • Seo, H.W.1    Han, K.2    Oh, Y.3
  • 96
    • 79958789722 scopus 로고    scopus 로고
    • Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae
    • Opriessnig T, Madson DM, Schalk S, et al. Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae. Theriogenology 2011;76:351-60
    • (2011) Theriogenology , vol.76 , pp. 351-360
    • Opriessnig, T.1    Madson, D.M.2    Schalk, S.3
  • 97
    • 84905275522 scopus 로고    scopus 로고
    • Impact of porcine circovirus type 2 (PCV2) vaccination on boar semen quality and quantity using two different vaccines
    • Caspari K, Henning H, Schreiber F, et al. Impact of porcine circovirus type 2 (PCV2) vaccination on boar semen quality and quantity using two different vaccines. Theriogenology 2014;82(4):574-9
    • (2014) Theriogenology , vol.82 , Issue.4 , pp. 574-579
    • Caspari, K.1    Henning, H.2    Schreiber, F.3
  • 98
    • 39149102499 scopus 로고    scopus 로고
    • Porcine circovirus type 2 (PCV2) vaccination of conventional pigs prevents viremia against PCV2 isolates of different genotypes and geographic origins
    • Fort M, Sibila M, Allepuz A, et al. Porcine circovirus type 2 (PCV2) vaccination of conventional pigs prevents viremia against PCV2 isolates of different genotypes and geographic origins. Vaccine 2008;26: 1063-71
    • (2008) Vaccine , vol.26 , pp. 1063-1071
    • Fort, M.1    Sibila, M.2    Allepuz, A.3
  • 99
    • 42049113242 scopus 로고    scopus 로고
    • Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2
    • Opriessnig T, Patterson AR, Elsener J, et al. Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2. Clin Vaccine Immunol 2008;15:397-401
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 397-401
    • Opriessnig, T.1    Patterson, A.R.2    Elsener, J.3
  • 100
    • 58549100979 scopus 로고    scopus 로고
    • Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3-months post vaccination
    • Opriessnig T, Patterson AR, Madson DM, et al. Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3-months post vaccination. Vaccine 2009;27:1002-7
    • (2009) Vaccine , vol.27 , pp. 1002-1007
    • Opriessnig, T.1    Patterson, A.R.2    Madson, D.M.3
  • 101
    • 84875028595 scopus 로고    scopus 로고
    • Comparative effects of vaccination against porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in a PCV2-PRRSV challenge model
    • Park C, Oh Y, Seo HW, et al. Comparative effects of vaccination against porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in a PCV2-PRRSV challenge model. Clin Vaccine Immunol 2013;20: 369-76
    • (2013) Clin Vaccine Immunol , vol.20 , pp. 369-376
    • Park, C.1    Oh, Y.2    Seo, H.W.3
  • 102
    • 84904466362 scopus 로고    scopus 로고
    • Comparison of four commercial one-dose porcine circovirus type 2 (PCV2) vaccines administered to pigs challenged with PCV2 and porcine reproductive and respiratory syndrome virus at 17 weeks postvaccination to control porcine respiratory disease complex u
    • Park C, Won Seo H, Han K, et al. Comparison of four commercial one-dose porcine circovirus type 2 (PCV2) vaccines administered to pigs challenged with PCV2 and porcine reproductive and respiratory syndrome virus at 17 weeks postvaccination to control porcine respiratory disease complex u. Clin Vaccine Immunol 2014;21(7):1021.
    • (2014) Clin Vaccine Immunol , vol.21 , Issue.7 , pp. 1021
    • Park, C.1    Won Seo, H.2    Han, K.3
  • 103
    • 84880080034 scopus 로고    scopus 로고
    • Efficacy of a piglet-specific commercial inactivated vaccine against Porcine circovirus type 2 in clinical field trials
    • Han K, Seo HW, Oh Y, et al. Efficacy of a piglet-specific commercial inactivated vaccine against Porcine circovirus type 2 in clinical field trials. Can J Vet Res 2013;77: 237-40
    • (2013) Can J Vet Res , vol.77 , pp. 237-240
    • Han, K.1    Seo, H.W.2    Oh, Y.3
  • 104
    • 84872176790 scopus 로고    scopus 로고
    • Porcine circovirus type 2 (PCV2) vaccination reduces PCV2 in a PCV2 and Salmonella enterica serovar Choleraesuis coinfection model
    • Takada-Iwao A, Seki M, Nakanishi M, et al. Porcine circovirus type 2 (PCV2) vaccination reduces PCV2 in a PCV2 and Salmonella enterica serovar Choleraesuis coinfection model. Vet Microbiol 2013; 162(1):219-23
    • (2013) Vet Microbiol , vol.162 , Issue.1 , pp. 219-223
    • Takada-Iwao, A.1    Seki, M.2    Nakanishi, M.3
  • 105
    • 84898779564 scopus 로고    scopus 로고
    • Clinical, virological, immunological and pathological evaluation of four porcine circovirus type 2 vaccines
    • Seo HW, Han K, Park C, et al. Clinical, virological, immunological and pathological evaluation of four porcine circovirus type 2 vaccines. Vet J 2014;200:65-70
    • (2014) Vet J , vol.200 , pp. 65-70
    • Seo, H.W.1    Han, K.2    Park, C.3
  • 106
    • 84893192416 scopus 로고    scopus 로고
    • Effect of porcine circovirus type 2 (PCV2) vaccination on PCV2-viremic piglets after experimental PCV2 challenge
    • Seo HW, Park C, Han K, et al. Effect of porcine circovirus type 2 (PCV2) vaccination on PCV2-viremic piglets after experimental PCV2 challenge. Vet Res 2014;45:13
    • (2014) Vet Res , vol.45 , pp. 13
    • Seo, H.W.1    Park, C.2    Han, K.3
  • 107
    • 58149378005 scopus 로고    scopus 로고
    • Efficacy of immunising pigs against porcine circovirus type 2 at three or six weeks of age
    • Cline G, Wilt V, Diaz E, et al. Efficacy of immunising pigs against porcine circovirus type 2 at three or six weeks of age. Vet Rec 2008; 163(25):737-40
    • (2008) Vet Rec , vol.163 , Issue.25 , pp. 737-740
    • Cline, G.1    Wilt, V.2    Diaz, E.3
  • 108
    • 39949085072 scopus 로고    scopus 로고
    • The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex
    • Fachinger V, Bischoff R, Jedidia SB, et al. The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex. Vaccine 2008;26:1488-99
    • (2008) Vaccine , vol.26 , pp. 1488-1499
    • Fachinger, V.1    Bischoff, R.2    Jedidia, S.B.3
  • 109
    • 41749109149 scopus 로고    scopus 로고
    • A field evaluation of mortality rate and growth performance in pigs vaccinated against porcine circovirus type 2
    • Horlen KP, Dritz SS, Nietfeld JC, et al. A field evaluation of mortality rate and growth performance in pigs vaccinated against porcine circovirus type 2. J Am Vet Med Assoc 2008;232:906-12
    • (2008) J Am Vet Med Assoc , vol.232 , pp. 906-912
    • Horlen, K.P.1    Dritz, S.S.2    Nietfeld, J.C.3
  • 110
    • 44749089050 scopus 로고    scopus 로고
    • Reduction of PMWS-associated clinical signs and co-infections by vaccination against PCV2
    • Kixmoller M, Ritzmann M, Eddicks M, et al. Reduction of PMWS-associated clinical signs and co-infections by vaccination against PCV2. Vaccine 2008;26: 3443-51
    • (2008) Vaccine , vol.26 , pp. 3443-3451
    • Kixmoller, M.1    Ritzmann, M.2    Eddicks, M.3
  • 111
    • 65649110085 scopus 로고    scopus 로고
    • Use of a one-dose subunit vaccine to prevent losses associated with porcine circovirus type 2
    • Desrosiers R, Clark E, Tremblay D, et al. Use of a one-dose subunit vaccine to prevent losses associated with porcine circovirus type 2. J Swine Heal Prod 2009;17:148-54
    • (2009) J Swine Heal Prod , vol.17 , pp. 148-154
    • Desrosiers, R.1    Clark, E.2    Tremblay, D.3
  • 112
    • 70849119372 scopus 로고    scopus 로고
    • A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) improves clinical, pathological and virological outcomes in postweaning multisystemic wasting syndrome affected farms
    • Segales J, Urniza A, Alegre A, et al. A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) improves clinical, pathological and virological outcomes in postweaning multisystemic wasting syndrome affected farms. Vaccine 2009;27:7313-21
    • (2009) Vaccine , vol.27 , pp. 7313-7321
    • Segales, J.1    Urniza, A.2    Alegre, A.3
  • 113
    • 84872499407 scopus 로고    scopus 로고
    • Concurrent vaccinations against PCV2 and PRRSV: Study on the specific immunity and clinical protection in naturally infected pigs
    • Martelli P, Ardigo P, Ferrari L, et al. Concurrent vaccinations against PCV2 and PRRSV: study on the specific immunity and clinical protection in naturally infected pigs. Vet Microbiol 2013;162:558-71
    • (2013) Vet Microbiol , vol.162 , pp. 558-571
    • Martelli, P.1    Ardigo, P.2    Ferrari, L.3
  • 114
    • 79955741820 scopus 로고    scopus 로고
    • Comparative efficacy of three commercial PCV2 vaccines in conventionally reared pigs
    • Lyoo K, Joo H, Caldwell B, et al. Comparative efficacy of three commercial PCV2 vaccines in conventionally reared pigs. Vet J 2011;189:58-62
    • (2011) Vet J , vol.189 , pp. 58-62
    • Lyoo, K.1    Joo, H.2    Caldwell, B.3
  • 115
    • 79251598994 scopus 로고    scopus 로고
    • A meta-analysis comparing the effect of PCV2 vaccines on average daily weight gain and mortality rate in pigs from weaning to slaughter
    • Kristensen CS, Baadsgaard NP, Toft N. A meta-analysis comparing the effect of PCV2 vaccines on average daily weight gain and mortality rate in pigs from weaning to slaughter. Prev Vet Med 2011;98(4):250-8
    • (2011) Prev Vet Med , vol.98 , Issue.4 , pp. 250-258
    • Kristensen, C.S.1    Baadsgaard, N.P.2    Toft, N.3
  • 116
    • 79955883578 scopus 로고    scopus 로고
    • Circovirus vaccination in pigs with subclinical porcine circovirus type 2 infection complicated by ileitis
    • Young MG, Cunningham GL, Sanford SE. Circovirus vaccination in pigs with subclinical porcine circovirus type 2 infection complicated by ileitis. J Swine Heal Prod 2011;19:6
    • (2011) J Swine Heal Prod , vol.19 , pp. 6
    • Young, M.G.1    Cunningham, G.L.2    Sanford, S.E.3
  • 117
    • 84857147035 scopus 로고    scopus 로고
    • Inactivated PCV2 one shot vaccine applied in 3-week-old piglets: Improvement of production parameters and interaction with maternally derived immunity
    • Fraile L, Grau-Roma L, Sarasola P, et al. Inactivated PCV2 one shot vaccine applied in 3-week-old piglets: improvement of production parameters and interaction with maternally derived immunity. Vaccine 2012;30:1986-92
    • (2012) Vaccine , vol.30 , pp. 1986-1992
    • Fraile, L.1    Grau-Roma, L.2    Sarasola, P.3
  • 118
    • 84876967471 scopus 로고    scopus 로고
    • Cost of post-weaning multi-systemic wasting syndrome and porcine circovirus type-2 subclinical infection in England-an economic disease model
    • Alarcon P, Rushton J, Wieland B. Cost of post-weaning multi-systemic wasting syndrome and porcine circovirus type-2 subclinical infection in England-an economic disease model. Prev Vet Med 2013;110(2):88-102
    • (2013) Prev Vet Med , vol.110 , Issue.2 , pp. 88-102
    • Alarcon, P.1    Rushton, J.2    Wieland, B.3
  • 119
    • 77954815934 scopus 로고    scopus 로고
    • Emergence of a new type of porcine circovirus in swine (PCV): A type 1 and type 2 PCV recombinant
    • Gagnon CA, Music N, Fontaine G, et al. Emergence of a new type of porcine circovirus in swine (PCV): a type 1 and type 2 PCV recombinant. Vet Microbiol 2010;144:18-23
    • (2010) Vet Microbiol , vol.144 , pp. 18-23
    • Gagnon, C.A.1    Music, N.2    Fontaine, G.3
  • 120
    • 84867618244 scopus 로고    scopus 로고
    • Reduction of porcine circovirus type 2 (PCV2) viremia by a reformulated inactivated chimeric PCV1-2 vaccine-induced humoral and cellular immunity after experimental PCV2 challenge
    • Seo HW, Oh Y, Han K, et al. Reduction of porcine circovirus type 2 (PCV2) viremia by a reformulated inactivated chimeric PCV1-2 vaccine-induced humoral and cellular immunity after experimental PCV2 challenge. BMC Vet Res 2012;8:194
    • (2012) BMC Vet Res , vol.8 , pp. 194
    • Seo, H.W.1    Oh, Y.2    Han, K.3
  • 121
    • 84904722027 scopus 로고    scopus 로고
    • Comparison of sow and/or piglet vaccination of 3 commercial porcine circovirus type 2 (PCV2) single-dose vaccines on pigs under experimental PCV2 challenge
    • Oh Y, Seo HW, Park C, et al. Comparison of sow and/or piglet vaccination of 3 commercial porcine circovirus type 2 (PCV2) single-dose vaccines on pigs under experimental PCV2 challenge. Vet Microbiol 2014;172(3-4):371-80
    • (2014) Vet Microbiol , vol.172 , Issue.3-4 , pp. 371-380
    • Oh, Y.1    Seo, H.W.2    Park, C.3
  • 122
    • 84905242589 scopus 로고    scopus 로고
    • Comparative analyses of humoral and cell-mediated immune responses upon vaccination with different commercially available single-dose porcine circovirus type 2 vaccines
    • Seo HW, Lee J, Han K, et al. Comparative analyses of humoral and cell-mediated immune responses upon vaccination with different commercially available single-dose porcine circovirus type 2 vaccines. Res Vet Sci 2014;97(1):38-42
    • (2014) Res Vet Sci , vol.97 , Issue.1 , pp. 38-42
    • Seo, H.W.1    Lee, J.2    Han, K.3
  • 123
    • 84874579145 scopus 로고    scopus 로고
    • Innate pro-inflammatory and adaptive immune cytokines in PBMC of vaccinated and unvaccinated pigs naturally exposed to porcine circovirus type 2 (PCV2) infection vary with the occurrence of the disease and the viral burden
    • Borghetti P, Morganti M, Saleri R, et al. Innate pro-inflammatory and adaptive immune cytokines in PBMC of vaccinated and unvaccinated pigs naturally exposed to porcine circovirus type 2 (PCV2) infection vary with the occurrence of the disease and the viral burden. Vet Microbiol 2013; 163(1-2):42-53
    • (2013) Vet Microbiol , vol.163 , Issue.1-2 , pp. 42-53
    • Borghetti, P.1    Morganti, M.2    Saleri, R.3
  • 124
    • 84884984591 scopus 로고    scopus 로고
    • Humoral response and colostral antibody transfer following "one-dose" pre-mating vaccination of sows against porcine circovirus type-2
    • Sibila M, Fraile L, Tico G, et al. Humoral response and colostral antibody transfer following "one-dose" pre-mating vaccination of sows against porcine circovirus type-2. Vet J 2013;197:881-3
    • (2013) Vet J , vol.197 , pp. 881-883
    • Sibila, M.1    Fraile, L.2    Tico, G.3
  • 126
    • 84862691128 scopus 로고    scopus 로고
    • Protective effect of the maternally derived porcine circovirus type 2 (PCV2)-specific cellular immune response in piglets by dam vaccination against PCV2 challenge
    • Oh Y, Seo HW, Han K, et al. Protective effect of the maternally derived porcine circovirus type 2 (PCV2)-specific cellular immune response in piglets by dam vaccination against PCV2 challenge. J Gen Virol 2012;93:1556-62
    • (2012) J Gen Virol , vol.93 , pp. 1556-1562
    • Oh, Y.1    Seo, H.W.2    Han, K.3
  • 127
    • 84892513431 scopus 로고    scopus 로고
    • Influence of age on the effectiveness of PCV2 vaccination in piglets with high levels of maternally derived antibodies
    • Haake M, Palzer A, Rist B, et al. Influence of age on the effectiveness of PCV2 vaccination in piglets with high levels of maternally derived antibodies. Vet Microbiol 2014;168:272-80
    • (2014) Vet Microbiol , vol.168 , pp. 272-280
    • Haake, M.1    Palzer, A.2    Rist, B.3
  • 129
    • 85026489437 scopus 로고    scopus 로고
    • Ten years of PCV2 in the UK
    • Burch D. Ten years of PCV2 in the UK. Pig Prog 2009;25:6
    • (2009) Pig Prog , vol.25 , pp. 6
    • Burch, D.1
  • 130
    • 79955535615 scopus 로고    scopus 로고
    • Characterization of a New Disease Syndrome Associated with Porcine Circovirus Type 2 in Previously Vaccinated Herds
    • Cino-Ozuna AG, Henry S, Hesse R, et al. Characterization of a New Disease Syndrome Associated with Porcine Circovirus Type 2 in Previously Vaccinated Herds. J Clin Microbiol 2011;49:2012-16
    • (2011) J Clin Microbiol , vol.49 , pp. 2012-2016
    • Cino-Ozuna, A.G.1    Henry, S.2    Hesse, R.3
  • 131
    • 76349090463 scopus 로고    scopus 로고
    • Differential effects of porcine circovirus type 2 (PCV2) vaccination on PCV2 genotypes at Japanese pig farms
    • Takahagi Y, Toki S, Nishiyama Y, et al. Differential effects of porcine circovirus type 2 (PCV2) vaccination on PCV2 genotypes at Japanese pig farms. J Vet Med Sci 2010;72(1):35-41
    • (2010) J Vet Med Sci , vol.72 , Issue.1 , pp. 35-41
    • Takahagi, Y.1    Toki, S.2    Nishiyama, Y.3
  • 132
    • 33751514317 scopus 로고    scopus 로고
    • Molecular evolution of porcine circovirus type 2 genomes: Phylogeny and clonality
    • Olvera A, Cortey M, Segalés J. Molecular evolution of porcine circovirus type 2 genomes: phylogeny and clonality. Virology 2007;357:175-85
    • (2007) Virology , vol.357 , pp. 175-185
    • Olvera, A.1    Cortey, M.2    Segalés, J.3
  • 133
    • 84871646075 scopus 로고    scopus 로고
    • A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection
    • Opriessnig T, O'Neill K, Gerber PF, et al. A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection. Vaccine 2013;31(3):487-94
    • (2013) Vaccine , vol.31 , Issue.3 , pp. 487-494
    • Opriessnig, T.1    O'Neill, K.2    Gerber, P.F.3
  • 134
    • 84874558397 scopus 로고    scopus 로고
    • Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. Concurrently infected with PPV2
    • Opriessnig T, Xiao CT, Gerber PF, et al. Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2. Vet Microbiol 2013;163:177-83
    • (2013) Vet Microbiol , vol.163 , pp. 177-183
    • Opriessnig, T.1    Xiao, C.T.2    Gerber, P.F.3
  • 135
    • 84869147607 scopus 로고    scopus 로고
    • Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States
    • Xiao C-T, Halbur PG, Opriessnig T. Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States. J Virol 2012;86:12469
    • (2012) J Virol , vol.86 , pp. 12469
    • Xiao, C.-T.1    Halbur, P.G.2    Opriessnig, T.3
  • 136
    • 84864057719 scopus 로고    scopus 로고
    • A porcine circovirus type 2 (PCV2) mutant with 234 amino acids in Capsid protein showed more virulence in vivo, compared with classical PCV2a/b strain
    • Guo L, Fu Y, Wang Y, et al. A porcine circovirus type 2 (PCV2) mutant with 234 amino acids in Capsid protein showed more virulence in vivo, compared with classical PCV2a/b strain. PLoS One 2012; 7(7):e41463
    • (2012) PLoS One , vol.7 , Issue.7 , pp. e41463
    • Guo, L.1    Fu, Y.2    Wang, Y.3
  • 137
    • 84998787273 scopus 로고    scopus 로고
    • Identification of an emergent porcine circovirus-2 in vaccinated pigs from a Brazilian farm during a postweaning multisystemic wasting syndrome outbreak
    • Salgado RL, Vidigal PMP, de Souza LFL, et al. Identification of an emergent porcine circovirus-2 in vaccinated pigs from a Brazilian farm during a postweaning multisystemic wasting syndrome outbreak. Genome Announc 2014;2(2):e00163-14
    • (2014) Genome Announc , vol.2 , Issue.2 , pp. e00163-e00214
    • Salgado, R.L.1    Pmp, V.2    De Souza Lfl3
  • 138
    • 84919382871 scopus 로고    scopus 로고
    • Genetic and antigenic characterization of a newly emerging porcine circovirus type 2b mutant first isolated in cases of vaccine failure in Korea
    • Seo HW, Park C, Kang I, et al. Genetic and antigenic characterization of a newly emerging porcine circovirus type 2b mutant first isolated in cases of vaccine failure in Korea. Arch Virol 2014;159(11):3107-11
    • (2014) Arch Virol , vol.159 , Issue.11 , pp. 3107-3111
    • Seo, H.W.1    Park, C.2    Kang, I.3
  • 139
    • 84903816299 scopus 로고    scopus 로고
    • Commercial PCV2a-based vaccines are effective in protecting naturally PCV2b-infected finisher pigs against experimental challenge with a 2012 mutant PCV2
    • Opriessnig T, Gerber PF, Xiao CT, et al. Commercial PCV2a-based vaccines are effective in protecting naturally PCV2b-infected finisher pigs against experimental challenge with a 2012 mutant PCV2. Vaccine 2014;32:4342-8
    • (2014) Vaccine , vol.32 , pp. 4342-4348
    • Opriessnig, T.1    Gerber, P.F.2    Xiao, C.T.3
  • 140
    • 84908266350 scopus 로고    scopus 로고
    • The mutant U.S. Strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarian-derived colostrum-deprived pigs
    • Opriessnig T, Xiao C-T, Gerber PF, et al. The mutant U.S. strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarian-derived colostrum-deprived pigs. J Gen Virol 2014;95(Pt 11):2495-503
    • (2014) J Gen Virol , vol.95 , pp. 2495-2503
    • Opriessnig, T.1    Xiao, C.-T.2    Gerber, P.F.3
  • 141
    • 84904437995 scopus 로고    scopus 로고
    • Genetic variability of porcine circovirus 2 in vaccinating and non-vaccinating commercial farms
    • Kekarainen T, Gonzalez A, Llorens A, et al. Genetic variability of porcine circovirus 2 in vaccinating and non-vaccinating commercial farms. J Gen Virol 2014;95(Pt 8):1734-42
    • (2014) J Gen Virol , vol.95 , pp. 1734-1742
    • Kekarainen, T.1    Gonzalez, A.2    Llorens, A.3
  • 142
    • 1642534298 scopus 로고    scopus 로고
    • Immunosuppression in postweaning multisystemic wasting syndrome affected pigs
    • Segales J, Domingo M, Chianini F, et al. Immunosuppression in postweaning multisystemic wasting syndrome affected pigs. Vet Microbiol 2004;98(2):151-8
    • (2004) Vet Microbiol , vol.98 , Issue.2 , pp. 151-158
    • Segales, J.1    Domingo, M.2    Chianini, F.3
  • 143
    • 78650568224 scopus 로고    scopus 로고
    • Recent advances in the epidemiology, diagnosis and control of diseases caused by porcine circovirus type 2
    • Grau-Roma L, Fraile L, Segalés J. Recent advances in the epidemiology, diagnosis and control of diseases caused by porcine circovirus type 2. Vet J 2011;187(1):23-32
    • (2011) Vet J , vol.187 , Issue.1 , pp. 23-32
    • Grau-Roma, L.1    Fraile, L.2    Segalés, J.3
  • 144
    • 73449125420 scopus 로고    scopus 로고
    • Use of register data to assess the association between use of antimicrobials and outbreak of Postweaning Multisystemic Wasting Syndrome (PMWS) in Danish pig herds
    • Vigre H, Dohoo IR, Stryhn H, et al. Use of register data to assess the association between use of antimicrobials and outbreak of Postweaning Multisystemic Wasting Syndrome (PMWS) in Danish pig herds. Prev Vet Med 2010;93:98-109
    • (2010) Prev Vet Med , vol.93 , pp. 98-109
    • Vigre, H.1    Dohoo, I.R.2    Stryhn, H.3
  • 145
    • 84923070373 scopus 로고    scopus 로고
    • PCV2 vaccination changing the pig industry. Part 3. Reduced antibiotic usage and improved performance go together
    • Glass F. PCV2 vaccination changing the pig industry. Part 3. Reduced antibiotic usage and improved performance go together. Pig Prog 2010;26(2):28-30
    • (2010) Pig Prog , vol.26 , Issue.2 , pp. 28-30
    • Glass, F.1
  • 146
    • 84899484979 scopus 로고    scopus 로고
    • Pigs naturally exposed to porcine circovirus type 2 (PCV2) generate antibody responses capable to neutralise PCV2 isolates of different genotypes and geographic origins
    • Kurtz S, Grau-Roma L, Cortey M, et al. Pigs naturally exposed to porcine circovirus type 2 (PCV2) generate antibody responses capable to neutralise PCV2 isolates of different genotypes and geographic origins. Vet Res 2014;45:29
    • (2014) Vet Res , vol.45 , pp. 29
    • Kurtz, S.1    Grau-Roma, L.2    Cortey, M.3
  • 147
    • 3242674572 scopus 로고    scopus 로고
    • Derivation of porcine circovirus type 2-negative pigs from positive breeding herds
    • Opriessnig T, Yu S, Thacker EL, et al. Derivation of porcine circovirus type 2-negative pigs from positive breeding herds. J Swine Health Prod 2004;12(4): 186-91
    • (2004) J Swine Health Prod , vol.12 , Issue.4 , pp. 186-191
    • Opriessnig, T.1    Yu, S.2    Thacker, E.L.3
  • 148
    • 79955896675 scopus 로고    scopus 로고
    • Establishment and maintenance of a porcine circovirus type 2 (PCV2)-free breeding herd on a site that experienced a natural outbreak of PCV2-associated reproductive disease
    • Patterson AR, Madson DM, Schalk S, et al. Establishment and maintenance of a porcine circovirus type 2 (PCV2)-free breeding herd on a site that experienced a natural outbreak of PCV2-associated reproductive disease. J Swine Heal Prod 2011;19(3):165-74
    • (2011) J Swine Heal Prod , vol.19 , Issue.3 , pp. 165-174
    • Patterson, A.R.1    Madson, D.M.2    Schalk, S.3
  • 149
    • 84903462350 scopus 로고    scopus 로고
    • Can Porcine circovirus type 2 (PCV2) infection be eradicated by mass vaccination?
    • Feng H, Blanco G, Segalés J, et al. Can Porcine circovirus type 2 (PCV2) infection be eradicated by mass vaccination? Vet Microbiol 2014;172:92-9
    • (2014) Vet Microbiol , vol.172 , pp. 92-99
    • Feng, H.1    Blanco, G.2    Segalés, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.