Comparative effects of vaccination against porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in a PCV2-PRRSV challenge model

Clinical and Vaccine Immunology

Volumn 20, Issue 3, 2013, Pages 369-376

  Park, Changhoon ^a   Oh, Yeonsu ^a   Seo, Hwi Won ^a   Han, Kiwon ^a   Chae, Chanhee ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERIVIRUS VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; FOSTERA PCV VACCINE; GAMMA INTERFERON; INGELVAC PRRS MLV; NEUTRALIZING ANTIBODY; PORCINE CIRCOVIRUS TYPE 2 VACCINE; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS DNA; VIRUS RNA; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIVIRUS INFECTION; ARTICLE; CD4+ CD8+ T LYMPHOCYTE; CIRCOVIRIDAE INFECTION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME LINKED IMMUNOSPOT ASSAY; EXPERIMENTAL INFECTION; GAMMA INTERFERON SECRETING CELL; HISTOPATHOLOGY; IMMUNE RESPONSE; LUNG PARENCHYMA; LYMPH NODE; MIXED INFECTION; NONHUMAN; PIGLET; PORCINE CIRCOVIRUS TYPE 2 INFECTION; PRIORITY JOURNAL; SECRETORY CELL; T LYMPHOCYTE; VACCINATION; VIRUS INHIBITION; VIRUS LOAD;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, CD4; ANTIGENS, CD8; CIRCOVIRIDAE INFECTIONS; CIRCOVIRUS; INTERFERON-GAMMA; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; VACCINATION; VIRAL VACCINES; VIREMIA;

EID: 84875028595     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00497-12     Document Type: Article

References (35)

1. Chae C. 2004. Postweaning multisystemic wasting syndrome: a review of aetiology, diagnosis and pathology. Vet. J. 168:41-49.
2. Chae C. 2005. A review of porcine circovirus 2-associated syndromes and diseases. Vet. J. 169:326-336.
3. Cavanagh D. 1997. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142:629-633.
4. Zimmerman JJ, Benfield DA, Dee SA, Murtaugh MP, Stadejek T, Stevenson GW, Torremorell M. 2012. Porcine reproductive and respiratory syndrome virus (porcine arterivirus), p 461-486. In Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW (ed), Diseases of swine, 10th ed. Wiley-Blackwell, West Sussex, United Kingdom.
5. Kim J, Chung HK, Chae C. 2003. Association of porcine circovirus 2 with porcine respiratory disease complex. Vet. J. 166:251-256.
6. Kim J, Chung HK, Jung T, Cho WS, Choi C, Chae C. 2002. Postweaning multisystemic wasting syndrome of pigs in Korea: prevalence, microscopic lesions and coexisting microorganisms. J. Vet. Med. Sci. 64:57-62.
7. Pallarés FJ, Halbur PG, Opriessnig T, Sorden SD, Villar D, Janke BH, Yaeger MJ, Larson DJ, Schwartz KJ, Yoon KJ, Hoffman LJ. 2002. Porcine circovirus type 2 (PCV-2) coinfections in US field cases of postweaning multisystemic wasting syndrome (PMWS). J. Vet. Diagn. Invest. 14:515-519.
8. Rovira A, Balasch M, Segalés J, García L, Plana-Durán J, Rosell C, Ellerbrok H, Mankertz A, Domingo M. 2002. Experimental inoculation of conventional pigs with porcine reproductive and respiratory syndrome virus and porcine circovirus 2. J. Virol. 76:3232-3239. 9. Opriessnig T, Madson DM, Prickett JR, Kuhar D, Lunney JK, Elsener J, Halbur PG. 2008. Effect of porcine circovirus type 2 (PCV2) vaccination on porcine reproductive and respiratory syndrome virus (PRRSV) and PCV2 coinfection. Vet. Microbiol. 131:103-114.
9. Allan GM, McNeilly F, Ellis J, Krakowka S, Meehan B, McNair I, Walker I, Kennedy S. 2000. Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication. Arch. Virol. 145:2421-2429.
10. Harms PA, Sorden SD, Halbur PG, Bolin SR, Larger KM, Morozov I, Paul PS. 2001. Experimental reproduction of severe disease in CD/CD pigs concurrently infected with type 2 porcine circovirus and porcine reproductive and respiratory syndrome virus. Vet. Pathol. 38:528-539.
11. Fenaux M, Opriessnig T, Halbur PG, Elvinger F, Meng XJ. 2004. A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs. J. Virol. 78:6297-6303.
12. Gagnon CA, del Castillo JR, Music N, Fontaine G, Harel J, Tremblay D. 2008. Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of Porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey. J. Vet. Diagn. Invest. 20:545-558.
13. Wasilk A, Callahan JD, Christopher-Hennings J, Gay TA, Fang Y, Dammen M, Reos ME, Torremorell M, Polson D, Mellencamp M, Nelson E, Nelson WM. 2004. Detection of U.S., Lelystad, and Europeanlike porcine reproductive and respiratory syndrome viruses and relative quantitation in boar semen and serum samples by real-time PCR. J. Clin. Microbiol. 42:4453-4461. 15. Pogranichnyy RM, Yoon KJ, Harms PA, Swenson SL, Zimmerman JJ, Sorden SD. 2000. Characterization of immune response of young pigs to porcine circovirus type 2 infection. Viral Immunol. 13:143-153.
14. Zuckermann FA, Garcia EA, Luque ID, Christopher-Hennings J, Doster A, Brito M, Osorio F. 2007. Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFNproducing cells and virological parameters of protection upon challenge. Vet. Microbiol. 123:69-85.
15. Han K, Seo HW, Shin JH, Oh Y, Kang I, Park C, Chae C. 2011. Effect of the modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine on European and North American PRRSV shedding in semen from infected boars. Clin. Vaccine Immunol. 18:1600-1607.
16. Bautista EM, Molitor TW. 1997. Cell-mediated immunity to porcine reproductive and respiratory syndrome virus in swine. Viral Immunol. 10:83-94.
17. Rodríguez-Arrioja GM, Segalés J, Balasch M, Rosell C, Quintant J, Folch JM, Plana-Durán J, Mankertz A, Domingo M. 2000. Serum antibodies to porcine circovirus type 1 and type 2 in pigs with and without PMWS. Vet. Rec. 146:762-764.
18. Diaz I, Mateu E. 2005. Use of ELISPOT and ELISA to evaluate IFN-, IL-10 and IL-4 responses in conventional pigs. Vet. Immunol. Immunopathol. 106:107-112.
19. Oh Y, Seo HW, Han K, Park C, Chae C. 2012. Protective effect of the maternally derived porcine circovirus type 2 (PCV2)-specific cellular immune response in piglets by dam vaccination against PCV2 challenge. J. Gen. Virol. 93:1556-1562.
20. Kim J, Choi C, Chae C. 2003. Pathogenesis of postweaning multisystemic wasting syndrome reproduced by co-infection with Korean isolates of porcine circovirus 2 and porcine parvovirus. J. Comp. Pathol. 128:52-59.
21. West KH, Bystrom JM, Wojnarowicz C, Shantz N, Jacobson M, Allan GM, Haines DM, Clark EG, Krakowka S, McNeilly F, Konoby C, Martin K, Ellis JA. 1999. Myocarditis and abortion associated with intrauterine infection of sows with porcine circovirus 2. J. Vet. Diagn. Invest. 11:530-532.
22. Han K, Seo HW, Oh Y, Kang I, Park C, Kang SH, Lee BH, Kwon B, Chae C. 2012. Evaluation of monoclonal antibody-based immunohistochemistry for the detection of European and North American porcine reproductive and respiratory syndrome virus and a comparison with in situ hybridization and reverse transcription polymerase chain reaction. J. Vet. Diagn. Invest. 24:719-724.
23. Kim J, Chae C. 2004. A comparison of virus isolation, polymerase chain reaction, immunohistochemistry, and in situ hybridization for the detection of porcine circovirus 2 and porcine parvovirus in experimentally and naturally coinfected pigs. J. Vet. Diagn. Invest. 16:45-50.
24. Halbur PG, Paul PS, Frey ML, Landgraf J, Eernisse K, Meng XJ, Lum MA, Andrews JJ, Rathje JA. 1995. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 32:648-660.
25. Kim J, Chae C. 2004. Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 in porcine circovirus 2-induced granulomatous inflammation. J. Comp. Pathol. 131:121-126.
26. Halbur PG, Paul PS, Frey ML, Landgraf J, Eernisse K, Meng XJ, Andrews JJ, Lum MA, Rathje JA. 1996. Comparison of the antigen distribution of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 33:159-170.
27. Saalmuller A, Redehasse MJ, Buhring Jonjic H-JS, Koszinowski UH. 1987. Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes. Eur. J. Immunol. 17:1297-1301. 30. Rodriques-Carreno MP, López-Fuertes L, Revilla C, Ezquerra A, Alonso F, Domínguez J. 2002. Phenotypic characterization of porcine IFN-producing lymphocytes by flow cytometry. J. Immunol. Methods 259:171-179.
28. Mateu E, Diaz I. 2008. The challenge of PRRS immunology. Vet. J. 177:345-351.
29. Meier WA, Galeota J, Osorio FA, Husmann RJ, Schnitzlein WM, Zuckermann FA. 2003. Gradual development of the interferon-response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination. Virology 309:18-31. 33. Lunney JK, Benfield DA, Rowland RRR. 2010. Porcine reproductive and respiratory syndrome virus: an update on an emerging and re-emerging viral disease of swine. Virus Res. 154:1-6.
30. Chae C. 2012. Commercial porcine circovirus type 2 vaccine: efficacy and clinical application. Vet. J. 194:151-157.
31. Fort M, Sibila M, Perez-Martin E, Nofrarias M, Mateu E, Segalés J. 2009. One dose of a porcine circovirus 2 (PCV2) sub-unit vaccine administered to 3-week-old conventional piglets elicits cell-mediated immunity and significantly reduces PCV2 viremia in an experimental model. Vaccine 27:4031-4037.
32. Opriessnig T, Patterson AR, Madson DM, Pal N, Halbur PG. 2009. Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3-months post vaccination. Vaccine 27:1002-1007.
33. Fachinger V, Bischoff R, Jedidia SB, Saalmuller A, Elbers K. 2008. The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex. Vaccine 26:1488-1499.
34. Opriessnig T, McKeown NE, Harmon KL, Meng XJ, Halbur PG. 2006. Porcine circovirus type 2 infection decreases the efficacy of a modified live porcine reproductive and respiratory syndrome virus vaccine. Clin. Vaccine Immunol. 13:923-929.
35. Sinha A, Shen HG, Schalk S, Beach NM, Huang YW, Halbur PG, Meng XJ, Opriessnig T. 2010. Porcine reproductive and respiratory syndrome virus infection at the time of porcine circovirus type 2 vaccination has no impact on vaccine efficacy. Clin. Vaccine Immunol. 17:1940-1945.