Late-stage C-H functionalization of complex alkaloids and drug molecules via intermolecular rhodium-carbenoid insertion

Nature Communications

Volumn 6, Issue , 2015, Pages

  He, Jing ^a   Hamann, Lawrence G ^a   Davies, Huw M L ^b   Beckwith, Rohan E J ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; BRUCINE; CARBENOID; CARBON; HYDROGEN; METHYL GROUP; NATURAL PRODUCT; RHODIUM; SECURININE; TERTIARY AMINE; AMINE; BIOLOGICAL PRODUCT; STRYCHNINE;

ALKALOID; CARBON; CATALYST; FUNCTIONAL GROUP; HYDROGEN; MOLECULAR ANALYSIS; RHODIUM;

ARTICLE; BIOLOGICAL ACTIVITY; CATALYST; CHEMICAL BOND; COMPLEX FORMATION; MOLECULE; NUCLEOPHILICITY; ANALOGS AND DERIVATIVES; CATALYSIS; CHEMISTRY; DRUG DESIGN; MEDICINAL CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES;

ALKALOIDS; AMINES; BIOLOGICAL PRODUCTS; CARBON; CATALYSIS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; RHODIUM; STRYCHNINE;

EID: 84923082876     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6943     Document Type: Article

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