Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging

Neurology

Volumn 47, Issue 2, 1996, Pages 454-461

  Meltzer, C C ^a,b   Zubieta, J K ^a   Brandt, J ^a   Tune, L E ^a   Mayberg, H S ^a   Frost, J J ^a,c  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; BRAIN METABOLISM; BRAIN TISSUE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; FEMALE; HUMAN; IMAGE ANALYSIS; LANGUAGE; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0029788383     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.47.2.454     Document Type: Article

References (60)

1. 11C-deoxyglucose accumulation, CSF monoamine metabolites and neuropsychological test performance in patients and healthy subjects. J Neurol Neurosurg Psychiatry 1991;54:672-678.
2. Polinsky RJ, Noble J, Di Chiro G, et al. Dominantly inherited Alzheimer's disease: cerebral glucose metabolism. J Neurol Neurosurg Psychiatry 1987;50:752-757.
3. Jamieson DG, Chawluk JB, Alavi A, et al. The effect of disease severity on local cerebral glucose metabolism in Alzheimer's disease. J Cereb Blood Flow Metab 1987;7(suppl 1): S410.
4. Duara R, Grady C, Haxby J, et al. Positron emission tomography in Alzheimer's disease. Neurology 1986;36:879-887.
5. Chawluk J, Alavi A, Hurtig H, et al. Altered patterns of regional cerebral glucose metabolism in aging and dementia. J Cereb Blood Flow Metab 1985;5(suppl 1):S121-S122.
6. Foster NL, Chase TN, Mansi L, et al. Cortical abnormalities in Alzheimer's disease. Ann Neurol 1984;16:649-654.
7. 18F-fluorodeoxyglucose. J Comput Assist Tomogr 1983;7:590-598,
8. Cutler NR, Haxby JV, Duara R, et al. Clinical history, brain metabolism, and neuropsychological function in Alzheimer's disease. Ann Neurol 1985;18:298-309.
9. 18F scan in Alzheimer's disease and multi-infarct dementia. Arch Neurol 1983;40:711-714.
10. Tanna NK, Kohn MI, Horwich DN, et al. Analysis of brain and cerebrospinal fluid volumes with MR imaging: impact on PET data correction for atrophy, part II. Aging and Alzheimer dementia. Radiology 1991;178:123-130.
11. Coleman PD, Flood DG. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol Aging 1987;8:521-545.
12. Creasey H, Schwartz M, Frederickson H, et al. Quantitative computed tomography in dementia of the Alzheimer type. Neurology 1986;36:1563-1568.
13. Brun A, Englund E. Regional pattern of degeneration in Alzheimer's disease: neuronal loss and histopathological grading. Histopathology 1981;5:549-564.
14. Terry RD, Peck A, DeTeresa R, et al. Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 1981;10:184-192.
15. Shefer VF. Absolute numbers of neurons and thickness of the cerebral cortex during aging, senile and vascular dementia, and Pick's and Alzheimer's diseases. Neurosci Behav Physiol 1972;6:319-324.
16. Dahlbeck SW, McCluney KW, Yeakley JW, et al. The intertruncal distance: a new MR measurement for the hippocampal atrophy of Alzheimer disease. AJNR Am J Neuroradiol 1991; 12:931-932.
17. DeCarli C, Kaye JA, Horwitz B, Rapoport SI. Critical analysis of the use of computer-assisted transverse axial tomography to study human brain in aging and dementia of the Alzheimer type. Neurology 1990;40:872-883.
18. Seab JP, Jagust WJ, Wong STS, et al. Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease. Magn Reson Med 1988;8:200-208.
19. George AE, Stylopoulos LA, de Leon MJ, et al. Temporal lobe CT diagnostic features of Alzheimer disease [abstract]. AJNR Am J Neuroradiol 1987;8:931.
20. Brinkman SD, Sarwar M, Levin HS, Morris HH. Quantitative indexes of computed tomography in dementia and normal aging. Radiology 1981;138:89-92.
21. Fazekas F, Alavi A, Chawluk JB, et al. Comparison of CT, MR, and PET in Alzheimer's dementia and normal aging. J Nucl Med 1989;30:1607-1615.
22. McGeer PL, Kamo H, Harrop R, et al. Comparison of PET, MRI, and CT with pathology in a proven case of Alzheimer's disease. Neurology 1986;36:1569-1574.
23. Mann DMA, Yates PO, Marcyniuk B. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. J Neurol Sci 1985;69: 139-159.
24. Mountjoy CQ, Roth M, Evans NJR, Evans HM. Cortical neuronal counts in normal elderly controls and demented patients. Neurobiol Aging 1983;4:1-11.
25. Kessler RM, Ellis JR, Eden M. Analysis of emission tomographic scan data: limitations imposed by resolution and background. J Comput Assist Tomogr 1984;8:514-522.
26. Mazziotta JC, Phelps ME, Plummer D, Kuhl DE. Quantitation in positron emission tomography: 5. Physical-anatomical effects. J Comput Assist Tomogr 1981;5:734-743.
27. de Leon MJ, Ferris SH, George AE, et al. Computed tomography and positron emission transaxial tomography evaluations of normal aging and Alzheimer's disease. J Cereb Blood Flow Metab 1983;3:391-394.
28. Lim KO, Zipursky RB, Watts MC, Pfefferbaum A. Decreased gray matter in normal aging: an in vivo magnetic resonance study. J Gerontol 1992;47:B26-30.
29. Albert MS, Sandor T, Boston DP, Moss M, Jolesz F. Measurment of age-related differences in gray matter, white matter, and cerebrospinal fluid. Radiology 1992;185(P):200.
30. Meltzer CC, Leal JP, Mayberg HS, et al. Correction of PET data for partial volume effects in human cerebral cortex by MR imaging. J Comput Assist Tomogr 1990;14:561-570.
31. Meltzer CC, Leal JP, Cromwell CC, et al. Partial volume correction of regional cerebral glucose metabolism in Alzheimer's disease. Radiology 1990;177(P):217.
32. Videen TO, Perlmutter JS, Mintun MA, Raichle ME. Regional correction of positron emission tomography data for the effects of cerebral atrophy. J Cereb Blood Flow Metab 1988;8:662-670.
33. American Psychiatric Association Work Group to Revise DSM-III. Diagnostic and Statistical Manual of Mental Disorders-Revised. Washington, DC: American Psychiatric Association, 1987:119-122.
34. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. J Psychiatr Res 1976;12:189-198.
35. Teng EL, Wimer C, Roberts E, et al. Alzheimer's dementia: performance on parallel forms of Dementia Assessment Battery. J Clin Exp Neuropsychol 1989;11:899-912.
36. Meltzer CC, Bryan RN, Holcomb HH, et al. Anatomical localization for PET using MR imaging. J Comput Assist Tomogr 1990;14:418-426.
37. Bruning JL, Kintz BL, eds. Computational handbook of statistics. Glenview, IL: Scott, Foresman & Co., 1987.
38. Smith G, deLeon M, Volkow N, et al. Topography of glucose metabolic deficits in Alzheimer's disease: evidence from cross-sectional and longitudinal studies. Soc Neurosci Abstr 1989; 15:1112.
39. Schlageter NL, Horowitz B, Creasey H, et al. Relation of measured brain glucose utilization and cerebral atrophy in man. J Neurol Neurosurg Psychiatry 1987;50:779-785.
40. Herscovitch P, Auchus AP, Gado M, et al. Correction of positron emission tomography data for cerebral atrophy. J Cereb Blood Flow Metab 1986;6:120-124.
41. Chawluk JB, Alavi A, Dann R, et al. Positron emission tomography in aging and dementia: effect of cerebral atrophy. J Nucl Med 1987;28:431-437.
42. Chawluk JB, Dann R, Alavi A, et al. The effect of focal cerebral atrophy in positron emission tomographic studies of aging and dementia. Nucl Med Biol 1990;17:797-804.
43. Filipek PA, Kennedy DN, Caviness VS, Rossnick SL, Spraggins TA, Starewicz PM. Magnetic resonance imaging-based brain morphometry: development and application to normal subjects. Ann Neurol 1989;25:61-67.
44. Condon BR, Patterson J, Wyper D, et al. A quantitative index of ventricular and extraventricular intracranial CSF volumes using MR imaging. J Comput Assist Tomogr 1986;10:784-792.
45. Wyper DJ, Pickard JD, Matheson M. Accuracy of ventricular volume estimation. J Neurol Neurosurg Psychiatry 1979;42: 345-350.
46. Penn RD, Belanger MG, Yasnoff MD. Ventricular volume in man computed from CAT scans. Ann Neurol 1978;3:216-223.
47. Alavi A, Newberg AB, Souder E, Berlin JA. Quantitative analysis of PET and MRI data in normal aging and Alzheimer's disease: atrophy-weighted total brain metabolism and absolute whole brain metabolism as reliable discriminators. J Nucl Med 1993;34:1681-1687.
48. Müller-Gärtner HW, Links JM, Prince JL, et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects. J Cereb Blood Flow Metab 1992;12:571-583.
49. Lavy S, Melamed E, Bentin S, et al. Bihemispheric decreases of regional cerebral blood flow in dementia: correlation with age-matched normal controls. Ann Neurol 1978;4:445-450.
50. Jolies PR, Chapman PR, Alavi A. PET, CT, and MRI in the evaluation of neuropsychiatric disorders: current applications. J Nucl Med 1989;30:1589-1606.
51. Haxby JV, Duara R, Grady GL, et al. Relations between neuropsychological and cerebral metabolic asymmetries in early Alzheimer's disease. J Cereb Blood Flow Metab 1985;5:193-200.
52. Reige WH, Metter EJ, Kuhl DE. Correlation of memory and brain glucose metabolism in depression and probable Alzheimer's disease. J Cereb Blood Flow Metab 1985;5(Suppl 1): S125-S126.
53. Foster NL, Chase TN, Fedio P, et al. Alzheimer's disease: focal cortical changes shown by positron emission tomography. Neurology 1983;33:961-965.
54. Friedland RP, Koss E, Jagust WJ. Lateral hemispheric asymmetries of glucose use in Alzheimer's disease: relationships to behavior, age of onset, and prognosis. J Cereb Blood Flow Metab 1985;5(Suppl 1):S123.
55. Jagust WJ, Reed BR, Seab PJ, et al. Alzheimer's disease: age at onset and single-photon emission computed tomographic patterns of regional cerebral blood flow. Arch Neurol 1990;47: 628-633.
56. Haxby JV, Grady CL, Koss E, et al. Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type. Arch Neurol 1990;47:753-760.
57. LeMay M. CT changes in dementing diseases: a review. AJNR Am J Neuroradiol 1986;7:841-853.
58. Gray E, Haug H, Chimelli L, et al. Prominent cortical atrophy with neuronal loss as correlate of human immunodeficiency virus encephalopathy. Acta Neuropathol 1991;82:229-233.
59. Ashtari M, Barr WB, Schaul N, Bogerts B. Three-dimensional fast low-angle shot imaging and computerized volume measurement of the hippocampus in patients with chronic epilepsy of the temporal lobe. AJNR Am J Neuroradiol 1991;12: 941-947.
60. Schroth G, Naegele T, Hlose U, et al. Reversible brain shrinkage in abstinent alcoholics, measured by MRI. Neuroradiology 1988;30:385-389.