The ROS-sensitive microRNA-9/9* controls the expression of mitochondrial tRNA-modifying enzymes and is involved in the molecular mechanism of MELAS syndrome

Human Molecular Genetics

Volumn 24, Issue 1, 2015, Pages 167-184

  Meseguer, Salvador ^a   Martínez Zamora, Ana ^a   García Arumí, Elena ^b,c   Andreu, Antonio L ^b,c   Armengod, M Eugenia ^a,c  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; GTP BINDING PROTEIN 3; I KAPPA B; MESSENGER RNA; MICRORNA; MICRORNA 9 9; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; MTO1 PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; TAURINE; TRMU PROTEIN; UNCLASSIFIED DRUG; URIDINE; CARRIER PROTEIN; GTPBP3 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE TRANSFER RNA; MIRN92 MICRORNA, HUMAN; MITOCHONDRIAL PROTEIN; MTO1 PROTEIN, HUMAN; RNA; RNA, MITOCHONDRIAL; TRANSFER RNA METHYLTRANSFERASE; TRMU PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CYBRID; DOWN REGULATION; ENZYME ACTIVITY; ENZYME MODIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MELAS SYNDROME; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR BIOLOGY; MOLECULAR PATHOLOGY; OXIDATIVE STRESS; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEADY STATE; TRANSCRIPTION REGULATION; CELL CULTURE; CELL NUCLEUS; GENETICS; METABOLISM; MITOCHONDRION;

CARRIER PROTEINS; CELL NUCLEUS; CELLS, CULTURED; DOWN-REGULATION; GTP-BINDING PROTEINS; HUMANS; MELAS SYNDROME; MICRORNAS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA; RNA, TRANSFER, LEU; SIGNAL TRANSDUCTION; TRNA METHYLTRANSFERASES;

EID: 84922588679     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu427     Document Type: Article

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