Translational misreading: A tRNA modification counteracts a +2 ribosomal frameshift

Genes and Development

Volumn 15, Issue 17, 2001, Pages 2295-2306

  Brégeon, Damien ^a   Colot, Vincent ^b,c   Radman, Miroslav ^a   Taddei, François ^a  

^a INSERM   (France)

^b INSTITUT JACQUES MONOD   (France)

^c CNRS   (France)

Author keywords

5 Methylaminomethyl 2 thio uridine; argU; gidA; mnmE; thdF; Translational fidelity

Indexed keywords

ARTICLE; CELL GROWTH; DNA REPLICATION; ESCHERICHIA COLI; FRAMESHIFT MUTATION; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; TRANSCRIPTION REGULATION;

ESCHERICHIA COLI;

EID: 0035449350     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.207701     Document Type: Article

References (67)

1. Isolation and characterization of the newly evolved ebg β- galactosidase of Escherichia coli K-12
2. Enhanced ribosome frameshifting in stationary phase cells
3. Mode of action of chloramphenicol
4. Stable RNA modification
5. Modified nucleosides at position 34 and 37 of tRNAs and their predicted coding capacities
6. Transfer RNA modification: Influence on translational frameshifting and metabolism
7. The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties
8. Evolution of a second gene for β-galactosidase in Escherichia coli
9. MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae
10. Effects of amino acid substitutions at the active site in Escherichia coli β-galactosidase
11. Rates of aminoacyl-tRNA selection at 29 sense codons in vivo
12. The elongation phase of protein synthesis
13. Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16 S ribosomal RNA
14. MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase
15. Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth rates
16. Protein oxidation in response to increased transcriptional or translational errors
17. Mistranslation in E. coli
18. An estimate of the global error frequency in translation
19. Novel E. coli mutants deficient in biosynthesis of 5-methylaminomethyl-2-thiouridine
20. Programmed translational frameshifting
21. How translational accuracy influences reading frame maintenance
22. Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
23. Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities
24. Analysis and prediction from Escherichia coli sequences, or E. coli In Silico
25. Dinucleotide deletions in neuronal transcripts: A novel type of mutation in non-familial Alzheimer's disease and Down syndrome patients
26. Modified nucleosides in the first positions of the anticodons of tRNA(Leu)4 and tRNA(Leu)5 from Escherichia coli
27. Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes
28. Uses of transposons with emphasis on Tn10
29. Genomic organization and physical mapping of the transfer RNA genes in Escherichia coli K12
30. The modification of the wobble base of tRNAGlu modulates the translation rate of glutamic acid codons in vivo
31. Translational accuracy and the fitness of bacteria
32. Limitations of translational accuracy
33. Genetic locations and database accession numbers of RNA-modifying and -editing enzymes
34. Identification of the paromomycin-resistance mutation in the 15 S rRNA gene of yeast mitochondria
35. The role of RNA polymerase in transcriptional fidelity
36. The frequency of errors in protein biosynthesis
37. Isolation and partial characterization of three Escherichia coli mutants with altered transfer ribonucleic acid methylases
38. Ribosome editing and the error catastrophe hypothesis of cellular aging
39. Codon usage tabulated from international DNA sequence databases: Status for the year 2000
40. Novel temperature-sensitive mutants of Escherichia coli that are unable to grow in the absence of wild-type tRNA6Leu
41. The allosteric three-site model for the ribosomal elongation cycle: Features and future
42. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
43. Cell cycle-dependent transcription from the gid and mioC promoters of Escherichia coli
44. Errors and alternatives in reading the universal genetic code
45. A new model for phenotypic suppression of frameshift mutations by mutant tRNAs
46. External suppression of a frameshift mutant in Salmonella
47. Two mutations giving low-level streptomycin resistance in Escherichia coli K 12
48. Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: The nature of in vivo DNA replication errors
49. Increased ribosomal accuracy increases a programmed translational frameshift in Escherichia coli
50. Protein oxidation and aging
51. Antisuppressor mutation in Escherichia coli defective in biosynthesis of 5-methylaminomethyl-2-thiouridine
52. Counteraction by MutT protein of transcriptional errors caused by oxidative damage
53. Transcriptional fidelity and proofreading by RNA polymerase II
54. EFTu provides an internal kinetic standard for translational accuracy
55. A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences
56. Mutations in RNA: A first example of molecular misreading in Alzheimer's disease
57. Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
58. The origin of replication, oriC, of the Escherichia coli chromosome: Genes near to oriC and construction of oriC deletion mutations
59. Mutation, recombination, and incipient speciation of bacteria in the laboratory
60. Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting
61. The paromomycin resistance mutation (parR-454) in the 15 S rRNA gene of the yeast Saccharomyces cerevisiae is involved in ribosomal frameshifting
62. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
63. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons