Production of squalene by squalene synthases and their truncated mutants in Escherichia coli

Journal of Bioscience and Bioengineering

Volumn 119, Issue 2, 2015, Pages 165-171

  Katabami, Akinori ^a   Li, Ling ^a   Iwasaki, Miki ^a   Furubayashi, Maiko ^a   Saito, Kyoichi ^a   Umeno, Daisuke ^a,b  

^a CHIBA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Bacterial production; Carotenoid; Mevalonate pathway; Squalene synthase; Triterpenoid

Indexed keywords

ESCHERICHIA COLI;

BACTERIAL PRODUCTION; CAROTENOID; MEVALONATE PATHWAY; SYNTHASES; TRITERPENOIDS;

ALIPHATIC COMPOUNDS;

BACTERIAL ENZYME; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; ISOPENTENYL DIPHOSPHATE; MEVALONATE KINASE; MEVALONIC ACID; PHOSPHOMEVALONATE KINASE; SQUALENE; SQUALENE SYNTHASE; MUTANT PROTEIN;

ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; TEMPERATURE; THERMOSYNECHOCOCCUS ELONGATUS; CHEMISTRY; CYANOBACTERIUM; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; THERMOSYNECHOCOCCUS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOBACTERIA; ESCHERICHIA COLI; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; HUMANS; MEVALONIC ACID; MUTANT PROTEINS; MUTATION; SQUALENE; TEMPERATURE;

EID: 84922575910     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2014.07.013     Document Type: Article

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