A molecular basis for the differential roles of Bubl and BubR1 in the spindle assembly checkpoint

eLife

Volumn 2015, Issue 4, 2015, Pages

  Overlack, Katharina ^a   Primorac, Ivana ^a   Vleugel, Mathijs ^b   Krenn, Veronica ^a   Maffini, Stefano ^a   Hoffmann, Ingrid ^a   Kops, Geert J P L ^b,c,d,e   Musacchio, Andrea ^a,f  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b Molecular Cancer Research   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

^e NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

^f UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Bub1; Bub3; BubR1; Casc5; Cdc20; Cell cycle; Divergence; Escape from adaptive conflict; Evolution; Gene duplication; Kinetochore; KMN network; Knl1; Mad2; Mis12; Mitotic checkpoint; Mps1; Reversine; Spindle assembly checkpoint; Sub functionalization

Indexed keywords

BUB1 RELATED PROTEIN; GREEN FLUORESCENT PROTEIN; PROTEIN BUB1; UNCLASSIFIED DRUG; BUB1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; MUTANT PROTEIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; TTK PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DELETION MUTANT; GEL MOBILITY SHIFT ASSAY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; M PHASE CELL CYCLE CHECKPOINT; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CENTROMERE; CHEMISTRY; HELA CELL LINE; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; HELA CELLS; HUMANS; KINETOCHORES; M PHASE CELL CYCLE CHECKPOINTS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES;

EID: 84922023754     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.05269     Document Type: Article

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