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Volumn 71, Issue 21, 2014, Pages 4179-4194

Neutrophil extracellular traps in cancer progression

Author keywords

Cancer; Inflammation; Metastatis; Neutrophil; Neutrophil extracellular traps

Indexed keywords

CATHEPSIN G; GELATINASE B; LEUKOCYTE ELASTASE; ANTIMICROBIAL CATIONIC PEPTIDE; CHROMATIN; DNA;

EID: 84922011987     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1683-3     Document Type: Review
Times cited : (193)

References (106)
  • 1
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • 19468060 1:CAS:528:DC%2BD1MXot1CisL8%3D
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A (2009) Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30:1073-1081
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 2
    • 84879604746 scopus 로고    scopus 로고
    • The metastasis-promoting roles of tumor-associated immune cells
    • 1:CAS:528:DC%2BC3sXltFCiurs%3D
    • Smith HA, Kang Y (2013) The metastasis-promoting roles of tumor-associated immune cells. J Mol Med (Berl) 91:411-429
    • (2013) J Mol Med (Berl) , vol.91 , pp. 411-429
    • Smith, H.A.1    Kang, Y.2
  • 3
    • 69249222379 scopus 로고    scopus 로고
    • Polarization of tumor-associated neutrophil phenotype by TGF-beta: "n1" versus "n2" TAN
    • 19732719 1:CAS:528:DC%2BD1MXhsVChs7vN 2754404
    • Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM (2009) Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell 16:183-194
    • (2009) Cancer Cell , vol.16 , pp. 183-194
    • Fridlender, Z.G.1    Sun, J.2    Kim, S.3    Kapoor, V.4    Cheng, G.5    Ling, L.6    Worthen, G.S.7    Albelda, S.M.8
  • 4
    • 25444456369 scopus 로고    scopus 로고
    • Tumor-associated CD8 + T cell tolerance induced by bone marrow-derived immature myeloid cells
    • 16177103 1:CAS:528:DC%2BD2MXhtVWltbjM 1350970
    • Kusmartsev S, Nagaraj S, Gabrilovich DI (2005) Tumor-associated CD8 + T cell tolerance induced by bone marrow-derived immature myeloid cells. J Immunol 175:4583-4592
    • (2005) J Immunol , vol.175 , pp. 4583-4592
    • Kusmartsev, S.1    Nagaraj, S.2    Gabrilovich, D.I.3
  • 5
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: Linking inflammation and cancer
    • 19342621 1:CAS:528:DC%2BD1MXjvFOjtrg%3D 2810498
    • Ostrand-Rosenberg S, Sinha P (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182:4499-4506
    • (2009) J Immunol , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 6
    • 84860484044 scopus 로고    scopus 로고
    • Tumor associated neutrophils: Friend or foe?
    • Fridlender ZG, Albelda SM (2012) Tumor associated neutrophils: friend or foe? Carcinogenesis 33:949-955
    • (2012) Carcinogenesis , vol.35 , pp. 949-955
    • Fridlender, Z.G.1    Albelda, S.M.2
  • 7
    • 84861190260 scopus 로고    scopus 로고
    • On the dual roles and polarized phenotypes of neutrophils in tumor development and progression
    • 21798756 1:STN:280:DC%2BC38zltVKksw%3D%3D
    • Piccard H, Muschel RJ, Opdenakker G (2012) On the dual roles and polarized phenotypes of neutrophils in tumor development and progression. Crit Rev Oncol Hematol 82:296-309
    • (2012) Crit Rev Oncol Hematol , vol.82 , pp. 296-309
    • Piccard, H.1    Muschel, R.J.2    Opdenakker, G.3
  • 8
    • 80052378182 scopus 로고    scopus 로고
    • The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff
    • 21628329 1:CAS:528:DC%2BC3MXht1SisLrL
    • Cavaillon JM (2011) The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff. J Leukoc Biol 90:413-424
    • (2011) J Leukoc Biol , vol.90 , pp. 413-424
    • Cavaillon, J.M.1
  • 9
    • 84863116466 scopus 로고    scopus 로고
    • Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils
    • 22348096 1:CAS:528:DC%2BC38XivFaqsLc%3D 3279406
    • Fridlender ZG, Sun J, Mishalian I, Singhal S, Cheng G, Kapoor V, Horng W, Fridlender G, Bayuh R, Worthen GS et al (2012) Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils. PLoS One 7:e31524
    • (2012) PLoS One , vol.7 , pp. 31524
    • Fridlender, Z.G.1    Sun, J.2    Mishalian, I.3    Singhal, S.4    Cheng, G.5    Kapoor, V.6    Horng, W.7    Fridlender, G.8    Bayuh, R.9    Worthen, G.S.10
  • 10
  • 12
    • 70350029796 scopus 로고    scopus 로고
    • NETs: A new strategy for using old weapons
    • 19699684 1:CAS:528:DC%2BD1MXhtlWitrzM
    • Papayannopoulos V, Zychlinsky A (2009) NETs: a new strategy for using old weapons. Trends Immunol 30:513-521
    • (2009) Trends Immunol , vol.30 , pp. 513-521
    • Papayannopoulos, V.1    Zychlinsky, A.2
  • 14
    • 84866360345 scopus 로고    scopus 로고
    • Neutrophil extracellular traps: Is immunity the second function of chromatin?
    • 22945932 1:CAS:528:DC%2BC38XhtlGkurnN 3432757
    • Brinkmann V, Zychlinsky A (2012) Neutrophil extracellular traps: is immunity the second function of chromatin? J Cell Biol 198:773-783
    • (2012) J Cell Biol , vol.198 , pp. 773-783
    • Brinkmann, V.1    Zychlinsky, A.2
  • 16
    • 84875442814 scopus 로고    scopus 로고
    • Neutrophil recruitment and function in health and inflammation
    • 23435331 1:CAS:528:DC%2BC3sXivFygtbo%3D
    • Kolaczkowska E, Kubes P (2013) Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol 13:159-175
    • (2013) Nat Rev Immunol , vol.13 , pp. 159-175
    • Kolaczkowska, E.1    Kubes, P.2
  • 17
    • 84866386143 scopus 로고    scopus 로고
    • Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis
    • 22980329 1:CAS:528:DC%2BC38XhtlKrtrnM
    • McDonald B, Urrutia R, Yipp BG, Jenne CN, Kubes P (2012) Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis. Cell Host Microbe 12:324-333
    • (2012) Cell Host Microbe , vol.12 , pp. 324-333
    • McDonald, B.1    Urrutia, R.2    Yipp, B.G.3    Jenne, C.N.4    Kubes, P.5
  • 20
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • 21785456 1:CAS:528:DC%2BC3MXptlaku7g%3D
    • Mantovani A, Cassatella MA, Costantini C, Jaillon S (2011) Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 11:519-531
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 21
    • 0026795415 scopus 로고
    • Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products
    • 1382715 1:CAS:528:DyaK3sXjslCmsg%3D%3D
    • Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A (1992) Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 80:2012-2020
    • (1992) Blood , vol.80 , pp. 2012-2020
    • Colotta, F.1    Re, F.2    Polentarutti, N.3    Sozzani, S.4    Mantovani, A.5
  • 22
    • 77955034793 scopus 로고    scopus 로고
    • Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development
    • 20610626 1:CAS:528:DC%2BC3cXovVamsrc%3D 2905495
    • Huh SJ, Liang S, Sharma A, Dong C, Robertson GP (2010) Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development. Cancer Res 70:6071-6082
    • (2010) Cancer Res , vol.70 , pp. 6071-6082
    • Huh, S.J.1    Liang, S.2    Sharma, A.3    Dong, C.4    Robertson, G.P.5
  • 23
    • 81255188938 scopus 로고    scopus 로고
    • The neutrophil in vascular inflammation
    • 22064428 1:CAS:528:DC%2BC3MXhsVOisLfL
    • Phillipson M, Kubes P (2011) The neutrophil in vascular inflammation. Nat Med 17:1381-1390
    • (2011) Nat Med , vol.17 , pp. 1381-1390
    • Phillipson, M.1    Kubes, P.2
  • 25
    • 77953435880 scopus 로고    scopus 로고
    • Regulation of extracellular chromatin release from neutrophils
    • 20375577 1:CAS:528:DC%2BD1MXktVGktL8%3D
    • Neeli I, Dwivedi N, Khan S, Radic M (2009) Regulation of extracellular chromatin release from neutrophils. J Innate Immun 1:194-201
    • (2009) J Innate Immun , vol.1 , pp. 194-201
    • Neeli, I.1    Dwivedi, N.2    Khan, S.3    Radic, M.4
  • 26
    • 80052294536 scopus 로고    scopus 로고
    • Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock
    • 21878229 3170094
    • Li Y, Liu B, Fukudome EY, Lu J, Chong W, Jin G, Liu Z, Velmahos GC, Demoya M, King DR et al (2011) Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock. Surgery 150:442-451
    • (2011) Surgery , vol.150 , pp. 442-451
    • Li, Y.1    Liu, B.2    Fukudome, E.Y.3    Lu, J.4    Chong, W.5    Jin, G.6    Liu, Z.7    Velmahos, G.C.8    Demoya, M.9    King, D.R.10
  • 27
    • 70350341210 scopus 로고    scopus 로고
    • DNase i inhibits a late phase of reactive oxygen species production in neutrophils
    • 20375609 1:CAS:528:DC%2BD1MXht1Orsb3N 2919508
    • Munafo DB, Johnson JL, Brzezinska AA, Ellis BA, Wood MR, Catz SD (2009) DNase I inhibits a late phase of reactive oxygen species production in neutrophils. J Innate Immun 1:527-542
    • (2009) J Innate Immun , vol.1 , pp. 527-542
    • Munafo, D.B.1    Johnson, J.L.2    Brzezinska, A.A.3    Ellis, B.A.4    Wood, M.R.5    Catz, S.D.6
  • 28
    • 78751574200 scopus 로고    scopus 로고
    • Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation
    • 21170021 1:CAS:528:DC%2BC3cXhsFyisb%2FL
    • Hakkim A, Fuchs TA, Martinez NE, Hess S, Prinz H, Zychlinsky A, Waldmann H (2011) Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. Nat Chem Biol 7:75-77
    • (2011) Nat Chem Biol , vol.7 , pp. 75-77
    • Hakkim, A.1    Fuchs, T.A.2    Martinez, N.E.3    Hess, S.4    Prinz, H.5    Zychlinsky, A.6    Waldmann, H.7
  • 29
    • 78049496216 scopus 로고    scopus 로고
    • Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
    • 20974816 1:CAS:528:DC%2BC3cXhsVamsrzM 3003309
    • Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A (2010) Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J Cell Biol 191:677-691
    • (2010) J Cell Biol , vol.191 , pp. 677-691
    • Papayannopoulos, V.1    Metzler, K.D.2    Hakkim, A.3    Zychlinsky, A.4
  • 31
    • 33745559712 scopus 로고    scopus 로고
    • Neutrophil serine proteases: Specific regulators of inflammation
    • 16799473 1:CAS:528:DC%2BD28XmtFegsLs%3D
    • Pham CT (2006) Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 6:541-550
    • (2006) Nat Rev Immunol , vol.6 , pp. 541-550
    • Pham, C.T.1
  • 35
    • 73549123475 scopus 로고    scopus 로고
    • Innate immune cells induce hemorrhage in tumors during thrombocytopenia
    • 19729481 1:CAS:528:DC%2BD1MXhtlWiurnP 2751565
    • Ho-Tin-Noe B, Carbo C, Demers M, Cifuni SM, Goerge T, Wagner DD (2009) Innate immune cells induce hemorrhage in tumors during thrombocytopenia. Am J Pathol 175:1699-1708
    • (2009) Am J Pathol , vol.175 , pp. 1699-1708
    • Ho-Tin-Noe, B.1    Carbo, C.2    Demers, M.3    Cifuni, S.M.4    Goerge, T.5    Wagner, D.D.6
  • 37
    • 84888316284 scopus 로고    scopus 로고
    • Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression
    • 24092389 1:CAS:528:DC%2BC3sXhsFKjtr7K
    • Mishalian I, Bayuh R, Levy L, Zolotarov L, Michaeli J, Fridlender ZG (2013) Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression. Cancer Immunol Immunother 62:1745-1756
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1745-1756
    • Mishalian, I.1    Bayuh, R.2    Levy, L.3    Zolotarov, L.4    Michaeli, J.5    Fridlender, Z.G.6
  • 38
    • 31544469201 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment
    • 16397239 1:CAS:528:DC%2BD28XhsFWgtw%3D%3D 1360653
    • Acuff HB, Carter KJ, Fingleton B, Gorden DL, Matrisian LM (2006) Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Cancer Res 66:259-266
    • (2006) Cancer Res , vol.66 , pp. 259-266
    • Acuff, H.B.1    Carter, K.J.2    Fingleton, B.3    Gorden, D.L.4    Matrisian, L.M.5
  • 40
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • 11081634 1:CAS:528:DC%2BD3cXnvF2ksLg%3D 2843102
    • Coussens LM, Tinkle CL, Hanahan D, Werb Z (2000) MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103:481-490
    • (2000) Cell , vol.103 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 42
    • 33747602354 scopus 로고    scopus 로고
    • Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
    • 16891410 1:CAS:528:DC%2BD28Xos1OjurY%3D 1531646
    • Nozawa H, Chiu C, Hanahan D (2006) Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc Natl Acad Sci USA 103:12493-12498
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12493-12498
    • Nozawa, H.1    Chiu, C.2    Hanahan, D.3
  • 44
    • 38149005534 scopus 로고    scopus 로고
    • Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice
    • 17884993 1:CAS:528:DC%2BD1cXks1Srsw%3D%3D
    • Daley JM, Thomay AA, Connolly MD, Reichner JS, Albina JE (2008) Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol 83(1):64-70
    • (2008) J Leukoc Biol , vol.83 , Issue.1 , pp. 64-70
    • Daley, J.M.1    Thomay, A.A.2    Connolly, M.D.3    Reichner, J.S.4    Albina, J.E.5
  • 45
    • 0036800759 scopus 로고    scopus 로고
    • Neutrophil-independent mechanisms of caspase-1 and IL-18-mediated ischemic acute tubular necrosis in mice
    • 12393844 1:CAS:528:DC%2BD38XotFGlurg%3D 150794
    • Melnikov VY, Faubel S, Siegmund B, Lucia MS, Ljubanovic D, Edelstein CL (2002) Neutrophil-independent mechanisms of caspase-1 and IL-18-mediated ischemic acute tubular necrosis in mice. J Clin Invest 110:1083-1091
    • (2002) J Clin Invest , vol.110 , pp. 1083-1091
    • Melnikov, V.Y.1    Faubel, S.2    Siegmund, B.3    Lucia, M.S.4    Ljubanovic, D.5    Edelstein, C.L.6
  • 46
    • 0346035761 scopus 로고    scopus 로고
    • Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis
    • 12626593 1:CAS:528:DC%2BD3sXhslOrt74%3D
    • Zhou J, Stohlman SA, Hinton DR, Marten NW (2003) Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. J Immunol 170:3331-3336
    • (2003) J Immunol , vol.170 , pp. 3331-3336
    • Zhou, J.1    Stohlman, S.A.2    Hinton, D.R.3    Marten, N.W.4
  • 47
    • 0038758881 scopus 로고    scopus 로고
    • Neutropenia alters lung cytokine production in mice and reduces their susceptibility to pulmonary cryptococcosis
    • 12778493 1:CAS:528:DC%2BD3sXkvF2ruro%3D
    • Mednick AJ, Feldmesser M, Rivera J, Casadevall A (2003) Neutropenia alters lung cytokine production in mice and reduces their susceptibility to pulmonary cryptococcosis. Eur J Immunol 33:1744-1753
    • (2003) Eur J Immunol , vol.33 , pp. 1744-1753
    • Mednick, A.J.1    Feldmesser, M.2    Rivera, J.3    Casadevall, A.4
  • 49
    • 0035136950 scopus 로고    scopus 로고
    • Neutrophil depletion exacerbates experimental Chagas' disease in BALB/c, but protects C57BL/6 mice through modulating the Th1/Th2 dichotomy in different directions
    • 11265643 1:CAS:528:DC%2BD3MXhtVGrsbo%3D
    • Chen L, Watanabe T, Watanabe H, Sendo F (2001) Neutrophil depletion exacerbates experimental Chagas' disease in BALB/c, but protects C57BL/6 mice through modulating the Th1/Th2 dichotomy in different directions. Eur J Immunol 31:265-275
    • (2001) Eur J Immunol , vol.31 , pp. 265-275
    • Chen, L.1    Watanabe, T.2    Watanabe, H.3    Sendo, F.4
  • 50
    • 0035284832 scopus 로고    scopus 로고
    • Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia
    • 11207291 1:CAS:528:DC%2BD3MXhs1Oisr0%3D
    • Tateda K, Moore TA, Deng JC, Newstead MW, Zeng X, Matsukawa A et al (2001) Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia. J Immunol 166:3355-3361
    • (2001) J Immunol , vol.166 , pp. 3355-3361
    • Tateda, K.1    Moore, T.A.2    Deng, J.C.3    Newstead, M.W.4    Zeng, X.5    Matsukawa, A.6
  • 51
    • 58849083367 scopus 로고    scopus 로고
    • Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome
    • 19158301 1:CAS:528:DC%2BD1MXhsVCnt7Y%3D
    • Stirling DP, Liu S, Kubes P, Yong VW (2009) Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci 29(3):753-764
    • (2009) J Neurosci , vol.29 , Issue.3 , pp. 753-764
    • Stirling, D.P.1    Liu, S.2    Kubes, P.3    Yong, V.W.4
  • 52
    • 84858794257 scopus 로고    scopus 로고
    • A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment
    • Rose S, Misharin A, Perlman H (2012) A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytom A 81(4):343-350
    • (2012) Cytom A , vol.81 , Issue.4 , pp. 343-350
    • Rose, S.1    Misharin, A.2    Perlman, H.3
  • 53
    • 34447561633 scopus 로고    scopus 로고
    • Neutrophil granules: A library of innate immunity proteins
    • 17627888 1:CAS:528:DC%2BD2sXotVGqtb0%3D
    • Borregaard N, Sorensen OE, Theilgaard-Monch K (2007) Neutrophil granules: a library of innate immunity proteins. Trends Immunol 28:340-345
    • (2007) Trends Immunol , vol.28 , pp. 340-345
    • Borregaard, N.1    Sorensen, O.E.2    Theilgaard-Monch, K.3
  • 54
    • 17644377258 scopus 로고    scopus 로고
    • How neutrophils kill microbes
    • 15771570 1:CAS:528:DC%2BD2MXktFOjtbY%3D 2092448
    • Segal AW (2005) How neutrophils kill microbes. Annu Rev Immunol 23:197-223
    • (2005) Annu Rev Immunol , vol.23 , pp. 197-223
    • Segal, A.W.1
  • 55
    • 0025239075 scopus 로고
    • Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties
    • 2312733 1:CAS:528:DyaK3cXhsFKmtr0%3D 296509
    • Campanelli D, Detmers PA, Nathan CF, Gabay JE (1990) Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. J Clin Invest 85:904-915
    • (1990) J Clin Invest , vol.85 , pp. 904-915
    • Campanelli, D.1    Detmers, P.A.2    Nathan, C.F.3    Gabay, J.E.4
  • 56
    • 0027407534 scopus 로고
    • Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: Defensins and azurocidin
    • 8452681 1:CAS:528:DyaK3sXitFSrs78%3D
    • Gabay JE, Almeida RP (1993) Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin. Curr Opin Immunol 5:97-102
    • (1993) Curr Opin Immunol , vol.5 , pp. 97-102
    • Gabay, J.E.1    Almeida, R.P.2
  • 57
    • 38849143983 scopus 로고    scopus 로고
    • Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions
    • 18021746 1:CAS:528:DC%2BD1cXhsVGktL8%3D
    • Korkmaz B, Moreau T, Gauthier F (2008) Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions. Biochimie 90:227-242
    • (2008) Biochimie , vol.90 , pp. 227-242
    • Korkmaz, B.1    Moreau, T.2    Gauthier, F.3
  • 58
    • 0026739037 scopus 로고
    • Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins
    • 1425666 1:CAS:528:DyaK3sXlsFKn
    • Scocchi M, Skerlavaj B, Romeo D, Gennaro R (1992) Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins. Eur J Biochem 209:589-595
    • (1992) Eur J Biochem , vol.209 , pp. 589-595
    • Scocchi, M.1    Skerlavaj, B.2    Romeo, D.3    Gennaro, R.4
  • 59
    • 84864941619 scopus 로고    scopus 로고
    • Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: Catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation
    • 22919124 3418687
    • Morimoto-Kamata R, Mizoguchi S, Ichisugi T, Yui S (2012) Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation. Mediators Inflamm 2012:456462
    • (2012) Mediators Inflamm , vol.2012 , pp. 456462
    • Morimoto-Kamata, R.1    Mizoguchi, S.2    Ichisugi, T.3    Yui, S.4
  • 60
    • 27144503317 scopus 로고    scopus 로고
    • Induction of multicellular 3-D spheroids of MCF-7 breast carcinoma cells by neutrophil-derived cathepsin G and elastase
    • 16128741 1:CAS:528:DC%2BD2MXhtVyhtLjN
    • Yui S, Tomita K, Kudo T, Ando S, Yamazaki M (2005) Induction of multicellular 3-D spheroids of MCF-7 breast carcinoma cells by neutrophil-derived cathepsin G and elastase. Cancer Sci 96:560-570
    • (2005) Cancer Sci , vol.96 , pp. 560-570
    • Yui, S.1    Tomita, K.2    Kudo, T.3    Ando, S.4    Yamazaki, M.5
  • 61
    • 74849101211 scopus 로고    scopus 로고
    • Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1
    • 19646811 1:CAS:528:DC%2BC3cXhtlSjuro%3D 2815079
    • Wilson TJ, Nannuru KC, Futakuchi M, Singh RK (2010) Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1. Cancer Lett 288:162-169
    • (2010) Cancer Lett , vol.288 , pp. 162-169
    • Wilson, T.J.1    Nannuru, K.C.2    Futakuchi, M.3    Singh, R.K.4
  • 62
    • 48649097728 scopus 로고    scopus 로고
    • Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand
    • 18632634 1:CAS:528:DC%2BD1cXovVCnsLg%3D
    • Wilson TJ, Nannuru KC, Futakuchi M, Sadanandam A, Singh RK (2008) Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand. Cancer Res 68:5803-5811
    • (2008) Cancer Res , vol.68 , pp. 5803-5811
    • Wilson, T.J.1    Nannuru, K.C.2    Futakuchi, M.3    Sadanandam, A.4    Singh, R.K.5
  • 64
    • 52949124048 scopus 로고    scopus 로고
    • Cancer the metastasis cascade
    • 18818347 1:CAS:528:DC%2BD1cXhtF2it7bO
    • Klein CA (2008) Cancer. The metastasis cascade. Science 321:1785-1787
    • (2008) Science , vol.321 , pp. 1785-1787
    • Klein, C.A.1
  • 65
    • 0031836105 scopus 로고    scopus 로고
    • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
    • 9585238 1:CAS:528:DyaK1cXjtFKgs7w%3D
    • Belaaouaj A, McCarthy R, Baumann M, Gao Z, Ley TJ, Abraham SN, Shapiro SD (1998) Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med 4:615-618
    • (1998) Nat Med , vol.4 , pp. 615-618
    • Belaaouaj, A.1    McCarthy, R.2    Baumann, M.3    Gao, Z.4    Ley, T.J.5    Abraham, S.N.6    Shapiro, S.D.7
  • 66
    • 0034144636 scopus 로고    scopus 로고
    • Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G
    • 10714686 1:CAS:528:DC%2BD3cXhslKqsLc%3D
    • Tkalcevic J, Novelli M, Phylactides M, Iredale JP, Segal AW, Roes J (2000) Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G. Immunity 12:201-210
    • (2000) Immunity , vol.12 , pp. 201-210
    • Tkalcevic, J.1    Novelli, M.2    Phylactides, M.3    Iredale, J.P.4    Segal, A.W.5    Roes, J.6
  • 67
    • 78249233244 scopus 로고    scopus 로고
    • Antimicrobial peptides: The ancient arm of the human immune system
    • 21178486
    • Wiesner J, Vilcinskas A (2010) Antimicrobial peptides: the ancient arm of the human immune system. Virulence 1:440-464
    • (2010) Virulence , vol.1 , pp. 440-464
    • Wiesner, J.1    Vilcinskas, A.2
  • 68
    • 77953488154 scopus 로고    scopus 로고
    • Neutrophil granules in health and disease
    • 20497300 1:STN:280:DC%2BC3cnot1eiuw%3D%3D
    • Hager M, Cowland JB, Borregaard N (2010) Neutrophil granules in health and disease. J Intern Med 268:25-34
    • (2010) J Intern Med , vol.268 , pp. 25-34
    • Hager, M.1    Cowland, J.B.2    Borregaard, N.3
  • 69
    • 84871388785 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: The role of neutrophils and neutrophil-derived elastase
    • 23227088 3514849
    • Grosse-Steffen T, Giese T, Giese N, Longerich T, Schirmacher P, Hansch GM, Gaida MM (2012) Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. Clin Dev Immunol 2012:720768
    • (2012) Clin Dev Immunol , vol.2012 , pp. 720768
    • Grosse-Steffen, T.1    Giese, T.2    Giese, N.3    Longerich, T.4    Schirmacher, P.5    Hansch, G.M.6    Gaida, M.M.7
  • 70
    • 84867407206 scopus 로고    scopus 로고
    • Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells
    • 22915586 1:CAS:528:DC%2BC38XhsFSgsLrK 3471748
    • Gregory AD, Hale P, Perlmutter DH, Houghton AM (2012) Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells. J Biol Chem 287:35341-35350
    • (2012) J Biol Chem , vol.287 , pp. 35341-35350
    • Gregory, A.D.1    Hale, P.2    Perlmutter, D.H.3    Houghton, A.M.4
  • 72
    • 84871335586 scopus 로고    scopus 로고
    • Polymorphonuclear neutrophils promote dyshesion of tumor cells and elastase-mediated degradation of E-cadherin in pancreatic tumors
    • 23001948 1:CAS:528:DC%2BC38Xhs1ShtLfP
    • Gaida MM, Steffen TG, Gunther F, Tschaharganeh DF, Felix K, Bergmann F, Schirmacher P, Hansch GM (2012) Polymorphonuclear neutrophils promote dyshesion of tumor cells and elastase-mediated degradation of E-cadherin in pancreatic tumors. Eur J Immunol 42:3369-3380
    • (2012) Eur J Immunol , vol.42 , pp. 3369-3380
    • Gaida, M.M.1    Steffen, T.G.2    Gunther, F.3    Tschaharganeh, D.F.4    Felix, K.5    Bergmann, F.6    Schirmacher, P.7    Hansch, G.M.8
  • 73
    • 35548933234 scopus 로고    scopus 로고
    • Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines
    • 17143494 1:CAS:528:DC%2BD2sXhtFagtLk%3D
    • Wada Y, Yoshida K, Tsutani Y, Shigematsu H, Oeda M, Sanada Y, Suzuki T, Mizuiri H, Hamai Y, Tanabe K et al (2007) Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines. Oncol Rep 17:161-167
    • (2007) Oncol Rep , vol.17 , pp. 161-167
    • Wada, Y.1    Yoshida, K.2    Tsutani, Y.3    Shigematsu, H.4    Oeda, M.5    Sanada, Y.6    Suzuki, T.7    Mizuiri, H.8    Hamai, Y.9    Tanabe, K.10
  • 74
    • 1342287837 scopus 로고    scopus 로고
    • Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression
    • 15003202 1:CAS:528:DC%2BD2cXhslSktL4%3D
    • Sun Z, Yang P (2004) Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression. Lancet Oncol 5:182-190
    • (2004) Lancet Oncol , vol.5 , pp. 182-190
    • Sun, Z.1    Yang, P.2
  • 75
    • 33748324486 scopus 로고    scopus 로고
    • Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha
    • 16918998 1:CAS:528:DC%2BD28XhtVyltrjO
    • Wada Y, Yoshida K, Hihara J, Konishi K, Tanabe K, Ukon K, Taomoto J, Suzuki T, Mizuiri H (2006) Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha. Cancer Sci 97:1037-1043
    • (2006) Cancer Sci , vol.97 , pp. 1037-1043
    • Wada, Y.1    Yoshida, K.2    Hihara, J.3    Konishi, K.4    Tanabe, K.5    Ukon, K.6    Taomoto, J.7    Suzuki, T.8    Mizuiri, H.9
  • 77
    • 84855678660 scopus 로고    scopus 로고
    • Growth effect of neutrophil elastase on breast cancer: Favorable action of sivelestat and application to anti-HER2 therapy
    • 22213283 1:CAS:528:DC%2BC38XitVWns7o%3D
    • Nawa M, Osada S, Morimitsu K, Nonaka K, Futamura M, Kawaguchi Y, Yoshida K (2012) Growth effect of neutrophil elastase on breast cancer: favorable action of sivelestat and application to anti-HER2 therapy. Anticancer Res 32:13-19
    • (2012) Anticancer Res , vol.32 , pp. 13-19
    • Nawa, M.1    Osada, S.2    Morimitsu, K.3    Nonaka, K.4    Futamura, M.5    Kawaguchi, Y.6    Yoshida, K.7
  • 80
    • 84864643012 scopus 로고    scopus 로고
    • Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies
    • 22611154 1:CAS:528:DC%2BC38Xht1WjsrrM 3418712
    • Fuchs TA, Kremer Hovinga JA, Schatzberg D, Wagner DD, Lammle B (2012) Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies. Blood 120:1157-1164
    • (2012) Blood , vol.120 , pp. 1157-1164
    • Fuchs, T.A.1    Kremer Hovinga, J.A.2    Schatzberg, D.3    Wagner, D.D.4    Lammle, B.5
  • 81
    • 3042683689 scopus 로고    scopus 로고
    • Circulating nucleosomes predict the response to chemotherapy in patients with advanced non-small cell lung cancer
    • 15447981 1:CAS:528:DC%2BD2cXnvVKqu70%3D
    • Holdenrieder S, Stieber P, von Pawel J, Raith H, Nagel D, Feldmann K, Seidel D (2004) Circulating nucleosomes predict the response to chemotherapy in patients with advanced non-small cell lung cancer. Clin Cancer Res 10:5981-5987
    • (2004) Clin Cancer Res , vol.10 , pp. 5981-5987
    • Holdenrieder, S.1    Stieber, P.2    Von Pawel, J.3    Raith, H.4    Nagel, D.5    Feldmann, K.6    Seidel, D.7
  • 82
    • 33747483360 scopus 로고    scopus 로고
    • Nucleosomes in colorectal cancer patients during radiochemotherapy
    • 16864976 1:CAS:528:DC%2BD28XotlaitLw%3D
    • Kremer A, Holdenrieder S, Stieber P, Wilkowski R, Nagel D, Seidel D (2006) Nucleosomes in colorectal cancer patients during radiochemotherapy. Tumour Biol 27:235-242
    • (2006) Tumour Biol , vol.27 , pp. 235-242
    • Kremer, A.1    Holdenrieder, S.2    Stieber, P.3    Wilkowski, R.4    Nagel, D.5    Seidel, D.6
  • 83
    • 77249100479 scopus 로고    scopus 로고
    • Plasma nucleosome levels might predict response to therapy in patients with advanced non-small-cell lung cancer
    • 20085866 1:CAS:528:DC%2BC3cXitVKktLo%3D
    • Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC (2010) Plasma nucleosome levels might predict response to therapy in patients with advanced non-small-cell lung cancer. Clin Lung Cancer 11:36-44
    • (2010) Clin Lung Cancer , vol.11 , pp. 36-44
    • Kumar, S.1    Guleria, R.2    Singh, V.3    Bharti, A.C.4    Mohan, A.5    Das, B.C.6
  • 84
    • 0001721119 scopus 로고    scopus 로고
    • Plasma Nucleosome Levels in Node-Negative Breast Cancer Patients
    • 11091744
    • Kuroi K, Tanaka C, Toi M (1999) Plasma Nucleosome Levels in Node-Negative Breast Cancer Patients. Breast Cancer 6:361-364
    • (1999) Breast Cancer , vol.6 , pp. 361-364
    • Kuroi, K.1    Tanaka, C.2    Toi, M.3
  • 86
    • 34250718748 scopus 로고    scopus 로고
    • Neutrophils promote aerogenous spread of lung adenocarcinoma with bronchioloalveolar carcinoma features
    • 17575214 1:CAS:528:DC%2BD2sXmsFCqtb4%3D
    • Wislez M, Antoine M, Rabbe N, Gounant V, Poulot V, Lavole A, Fleury-Feith J, Cadranel J (2007) Neutrophils promote aerogenous spread of lung adenocarcinoma with bronchioloalveolar carcinoma features. Clin Cancer Res 13:3518-3527
    • (2007) Clin Cancer Res , vol.13 , pp. 3518-3527
    • Wislez, M.1    Antoine, M.2    Rabbe, N.3    Gounant, V.4    Poulot, V.5    Lavole, A.6    Fleury-Feith, J.7    Cadranel, J.8
  • 88
    • 80052510176 scopus 로고    scopus 로고
    • Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis
    • 21703402 1:CAS:528:DC%2BC3MXpvVKlu74%3D 3123873
    • Narasaraju T, Yang E, Samy RP, Ng HH, Poh WP, Liew AA, Phoon MC, van Rooijen N, Chow VT (2011) Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol 179:199-210
    • (2011) Am J Pathol , vol.179 , pp. 199-210
    • Narasaraju, T.1    Yang, E.2    Samy, R.P.3    Ng, H.H.4    Poh, W.P.5    Liew, A.A.6    Phoon, M.C.7    Van Rooijen, N.8    Chow, V.T.9
  • 89
    • 79952236601 scopus 로고    scopus 로고
    • LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis
    • 21363926 1:CAS:528:DC%2BC3MXisFCnsbY%3D
    • Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, Ferri LE (2011) LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Cancer Res 71:1989-1998
    • (2011) Cancer Res , vol.71 , pp. 1989-1998
    • Hsu, R.Y.1    Chan, C.H.2    Spicer, J.D.3    Rousseau, M.C.4    Giannias, B.5    Rousseau, S.6    Ferri, L.E.7
  • 90
    • 68349101949 scopus 로고    scopus 로고
    • Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms
    • 19431213 1:CAS:528:DC%2BD1MXovVelsLc%3D
    • McDonald B, Spicer J, Giannais B, Fallavollita L, Brodt P, Ferri LE (2009) Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms. Int J Cancer 125:1298-1305
    • (2009) Int J Cancer , vol.125 , pp. 1298-1305
    • McDonald, B.1    Spicer, J.2    Giannais, B.3    Fallavollita, L.4    Brodt, P.5    Ferri, L.E.6
  • 91
    • 84883584923 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner
    • 23809486
    • Rousseau MC, Hsu RY, Spicer JD, McDonald B, Chan CH, Perera RM, Giannias B, Chow SC, Rousseau S, Law S et al (2013) Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner. Surgery 154:69-77
    • (2013) Surgery , vol.154 , pp. 69-77
    • Rousseau, M.C.1    Hsu, R.Y.2    Spicer, J.D.3    McDonald, B.4    Chan, C.H.5    Perera, R.M.6    Giannias, B.7    Chow, S.C.8    Rousseau, S.9    Law, S.10
  • 92
    • 84865107210 scopus 로고    scopus 로고
    • Neutrophils Promote Liver Metastasis via Mac-1-Mediated Interactions with Circulating Tumor Cells
    • 22751466 1:CAS:528:DC%2BC38XhtF2rtr3I
    • Spicer JD, McDonald B, Cools-Lartigue JJ, Chow SC, Giannias B, Kubes P, Ferri LE (2012) Neutrophils Promote Liver Metastasis via Mac-1-Mediated Interactions with Circulating Tumor Cells. Cancer Res 72:3919-3927
    • (2012) Cancer Res , vol.72 , pp. 3919-3927
    • Spicer, J.D.1    McDonald, B.2    Cools-Lartigue, J.J.3    Chow, S.C.4    Giannias, B.5    Kubes, P.6    Ferri, L.E.7
  • 93
    • 41549157282 scopus 로고    scopus 로고
    • Two-dimensional kinetics of beta 2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow
    • 18199704 1:CAS:528:DC%2BD1cXjsFCjur0%3D 2678683
    • Liang S, Fu C, Wagner D, Guo H, Zhan D, Dong C, Long M (2008) Two-dimensional kinetics of beta 2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow. Am J Physiol Cell Physiol 294:C743-C753
    • (2008) Am J Physiol Cell Physiol , vol.294 , pp. 743-C753
    • Liang, S.1    Fu, C.2    Wagner, D.3    Guo, H.4    Zhan, D.5    Dong, C.6    Long, M.7
  • 94
    • 77950187372 scopus 로고    scopus 로고
    • Effects of the Tumor-Leukocyte Microenvironment on Melanoma-Neutrophil Adhesion to the Endothelium in a Shear Flow
    • 19865613 2768417
    • Liang S, Hoskins M, Khanna P, Kunz RF, Dong C (2008) Effects of the Tumor-Leukocyte Microenvironment on Melanoma-Neutrophil Adhesion to the Endothelium in a Shear Flow. Cell Mol Bioeng 1:189-200
    • (2008) Cell Mol Bioeng , vol.1 , pp. 189-200
    • Liang, S.1    Hoskins, M.2    Khanna, P.3    Kunz, R.F.4    Dong, C.5
  • 96
    • 0027395309 scopus 로고
    • Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice
    • 8427781 1:CAS:528:DyaK3sXhvVaqt7Y%3D 1968215
    • Sugihara S, Yamamoto T, Tanaka H, Kambara T, Hiraoka T, Miyauchi Y (1993) Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer 67:66-70
    • (1993) Br J Cancer , vol.67 , pp. 66-70
    • Sugihara, S.1    Yamamoto, T.2    Tanaka, H.3    Kambara, T.4    Hiraoka, T.5    Miyauchi, Y.6
  • 97
    • 79952456050 scopus 로고    scopus 로고
    • Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase i
    • 21194552 1:CAS:528:DC%2BC3MXjsFCnsLc%3D
    • Patutina O, Mironova N, Ryabchikova E, Popova N, Nikolin V, Kaledin V, Vlassov V, Zenkova M (2011) Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I. Biochimie 93:689-696
    • (2011) Biochimie , vol.93 , pp. 689-696
    • Patutina, O.1    Mironova, N.2    Ryabchikova, E.3    Popova, N.4    Nikolin, V.5    Kaledin, V.6    Vlassov, V.7    Zenkova, M.8
  • 98
    • 0037439962 scopus 로고    scopus 로고
    • The prognostic value of polymorphonuclear leukocyte elastase in patients with primary breast cancer
    • 12543785 1:CAS:528:DC%2BD3sXnt1Kktw%3D%3D
    • Foekens JA, Ries C, Look MP, Gippner-Steppert C, Klijn JG, Jochum M (2003) The prognostic value of polymorphonuclear leukocyte elastase in patients with primary breast cancer. Cancer Res 63:337-341
    • (2003) Cancer Res , vol.63 , pp. 337-341
    • Foekens, J.A.1    Ries, C.2    Look, M.P.3    Gippner-Steppert, C.4    Klijn, J.G.5    Jochum, M.6
  • 100
    • 79957723847 scopus 로고    scopus 로고
    • Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer
    • 21557207 1:CAS:528:DC%2BC3MXmsF2qtrk%3D
    • Makino H, Kunisaki C, Kosaka T, Akiyama H, Morita S, Endo I (2011) Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer. Br J Surg 98:975-982
    • (2011) Br J Surg , vol.98 , pp. 975-982
    • Makino, H.1    Kunisaki, C.2    Kosaka, T.3    Akiyama, H.4    Morita, S.5    Endo, I.6
  • 101
    • 80051546730 scopus 로고    scopus 로고
    • Optimal period for the prophylactic administration of neutrophil elastase inhibitor for patients with esophageal cancer undergoing esophagectomy
    • 21479682
    • Iwahashi M, Nakamori M, Nakamura M, Ojima T, Naka T, Yamaue H (2011) Optimal period for the prophylactic administration of neutrophil elastase inhibitor for patients with esophageal cancer undergoing esophagectomy. World J Surg 35:1573-1579
    • (2011) World J Surg , vol.35 , pp. 1573-1579
    • Iwahashi, M.1    Nakamori, M.2    Nakamura, M.3    Ojima, T.4    Naka, T.5    Yamaue, H.6
  • 102
    • 77957128514 scopus 로고    scopus 로고
    • Prospective randomized controlled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer
    • 19788440 1:STN:280:DC%2BC3cnksVKktg%3D%3D
    • Kawahara Y, Ninomiya I, Fujimura T, Funaki H, Nakagawara H, Takamura H, Oyama K, Tajima H, Fushida S, Inaba H et al (2010) Prospective randomized controlled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer. Dis Esophagus 23:329-339
    • (2010) Dis Esophagus , vol.23 , pp. 329-339
    • Kawahara, Y.1    Ninomiya, I.2    Fujimura, T.3    Funaki, H.4    Nakagawara, H.5    Takamura, H.6    Oyama, K.7    Tajima, H.8    Fushida, S.9    Inaba, H.10
  • 103
    • 77958152008 scopus 로고    scopus 로고
    • Neutrophils: Cinderella of innate immune system
    • 20828640 1:CAS:528:DC%2BC3cXhtleqt7fL
    • Kumar V, Sharma A (2010) Neutrophils: Cinderella of innate immune system. Int Immunopharmacol 10:1325-1334
    • (2010) Int Immunopharmacol , vol.10 , pp. 1325-1334
    • Kumar, V.1    Sharma, A.2
  • 104
    • 84874117229 scopus 로고    scopus 로고
    • Protumor and antitumor functions of neutrophil granulocytes
    • 23007469 1:CAS:528:DC%2BC3sXisVaisr0%3D
    • Brandau S, Dumitru CA, Lang S (2013) Protumor and antitumor functions of neutrophil granulocytes. Semin Immunopathol 35(2):163-176
    • (2013) Semin Immunopathol , vol.35 , Issue.2 , pp. 163-176
    • Brandau, S.1    Dumitru, C.A.2    Lang, S.3
  • 105
    • 83055182228 scopus 로고    scopus 로고
    • Neutrophil elastase enhances sputum solubilization in cystic fibrosis patients receiving DNase therapy
    • 22174830 1:CAS:528:DC%2BC38Xht1Sr 3235130
    • Papayannopoulos V, Staab D, Zychlinsky A (2011) Neutrophil elastase enhances sputum solubilization in cystic fibrosis patients receiving DNase therapy. PLoS One 6:e28526
    • (2011) PLoS One , vol.6 , pp. 28526
    • Papayannopoulos, V.1    Staab, D.2    Zychlinsky, A.3


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