Cathepsin G-mediated enhanced TGF-β signaling promotes angiogenesis via upregulation of VEGF and MCP-1

Cancer Letters

Volumn 288, Issue 2, 2010, Pages 162-169

  Wilson, Thomas J ^a   Nannuru, Kalyan C ^a   Futakuchi, Mitsuru ^b   Singh, Rakesh K ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Bone metastasis; Breast cancer; Cathepsin G; TGF

Indexed keywords

CATHEPSIN G; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER INVASION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION; TUMOR VASCULARIZATION; UPREGULATION;

ANIMALS; ANTIBODIES; BONE NEOPLASMS; BREAST NEOPLASMS; CATHEPSIN G; CELL LINE, TUMOR; CHEMOKINE CCL2; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; SIGNAL TRANSDUCTION; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 74849101211     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.06.035     Document Type: Article

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