AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells

Experimental Eye Research

Volumn 132, Issue , 2015, Pages 136-150

  Park, Yong H ^a   Mueller, Brett H ^a   McGrady, Nolan R ^a   Ma, Hai Ying ^a   Yorio, Thomas ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

AMPA receptor; CAMP response element binding protein; Desensitization; Excitotoxicity; Primary retinal ganglion cells

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; CALCIUM; CASPASE 3; CASPASE 7; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ETHIDIUM; FODRIN; HOMODIMER; KAINIC ACID; KAINIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; AMINO ACID RECEPTOR STIMULATING AGENT; CASPASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCEIN-AM ASSAY; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXCITOTOXICITY; EXTRACELLULAR CALCIUM; EYE TOXICITY; FEMALE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LUCIFERASE ASSAY; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PURIFICATION; RAT; RECEPTOR DOWN REGULATION; RETINA GANGLION CELL; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; AGONISTS; ANIMAL; CELL CULTURE; DRUG EFFECTS; MALE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CASPASES; CELLS, CULTURED; CREB-BINDING PROTEIN; EXCITATORY AMINO ACID AGONISTS; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RETINAL GANGLION CELLS;

EID: 84921971882     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2015.01.026     Document Type: Article

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