NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation

Cell Death and Disease

Volumn 5, Issue 10, 2014, Pages

  Kim, S R ^a   Kim, D I ^a   Kim, S H ^b   Lee, H ^a   Lee, K S ^a   Cho, S H ^c   Lee, Y C ^a  

^a Chonbuk National University Medical School   (South Korea)

^b LG Chemical Ltd   (South Korea)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; FUSED HETEROCYCLIC RINGS; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MITOCHONDRIAL DNA; NECROX-5; NLRP3 PROTEIN, HUMAN; OVALBUMIN; PEROXIDASE; SULFONE;

ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; INFLAMMATORY CELL; MODULATION; MOUSE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; ANIMAL; ASTHMA; BLOOD; BRONCHUS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; HUMAN; HYPERSENSITIVITY; INFLAMMATION; INTRACELLULAR SPACE; LUNG; LUNG LAVAGE; MALE; METABOLISM; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; TRACHEA;

MUS;

ANIMALS; ASTHMA; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; DNA, MITOCHONDRIAL; EPITHELIAL CELLS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; HYPERSENSITIVITY; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; INTRACELLULAR SPACE; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MIDDLE AGED; MITOCHONDRIA; OVALBUMIN; PEROXIDASE; REACTIVE OXYGEN SPECIES; SULFONES; TRACHEA;

EID: 84921966782     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.460     Document Type: Article

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