An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

Gastroenterology

Volumn 117, Issue 1, 1999, Pages 181-190

  Mansouri, A ^a   Gaou, I ^a   De Kerguenec, C ^a   Amsellem, S ^a   Haouzi, D ^a   Berson, A ^a   Moreau, A ^a   Feldmann, G ^a   Letteron, P ^a   Pessayre, D ^a   Fromenty, B ^a  

^a BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; ALCOHOL; ANTIOXIDANT; CELL NUCLEUS DNA;

ALCOHOL INTOXICATION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DNA STRAND BREAKAGE; DOSE RESPONSE; HYBRIDIZATION; LIPID PEROXIDATION; LIVER MITOCHONDRION; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

EID: 0032990245     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70566-4     Document Type: Article

References (52)

1. MD Brown DC Wallace Molecular basis of mitochondrial DNA disease J Bioenerg Biomembr 26 1994 273 289
2. EA Schon E Bonilla S DiMauro Mitochondrial DNA mutations and pathogenesis J Bioenerg Biomembr 29 1997 131 149
3. DC Wallace Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 256 1992 628 632
4. B Fromenty R Carrozzo S Shanske EA Schon High proportions of mtDNA duplications in patients with Kearns–Sayre syndrome occur in the heart Am J Med Genet 71 1997 443 452
5. MK Shigenaga TM Hagen BN Ames Oxidative damage and mitochondrial decay in aging Proc Natl Acad Sci USA 91 1994 10771 10778
6. C Richter JW Park BN Ames Normal oxidative damage to mitochondrial and nuclear DNA is extensive Proc Natl Acad Sci USA 85 1988 6465 6467
7. A Mansouri I Gaou B Fromenty A Berson P Lettéron C Degott S Erlinger D Pessayre Premature oxidative aging of hepatic mitochondrial DNA in Wilson's disease Gastroenterology 113 1997 599 605
8. B Fromenty S Grimbert A Mansouri M Beaugrand S Erlinger A Rötig D Pessayre Hepatic mitochondrial DNA deletion in alcoholics: association with microvesicular steatosis Gastroenterology 108 1995 193 200
9. A Mansouri B Fromenty A Berson MA Robin S Grimbert M Beaugrand S Erlinger D Pessayre Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients J Hepatol 27 1997 96 102
10. B Fromenty D Pessayre Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity Pharmacol Ther 67 1995 101 154
11. R Nordmann C Ribière H Rouach Implication of free radical mechanisms in ethanol-induced cellular injury Free Radic Biol Med 12 1992 219 240
12. I Kurose H Higuchi S Miura H Saito N Watanabe R Hokari M Hirokawa M Takaishi S Zeki T Nakamura H Ebinuma S Kato H Ishii Oxidative stress–mediated apoptosis of hepatocytes exposed to acute ethanol intoxication Hepatology 25 1997 368 378
13. A Cahill X Wang JB Hoek Increased oxidative damage to mitochondrial DNA following chronic ethanol consumption Biochem Biophys Res Commun 235 1997 286 290
14. B Fromenty A Berson D Pessayre Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation J Hepatol 26 suppl 1 1997 13 22
15. P Wieland BH Lauterburg Oxidation of mitochondrial proteins and DNA following administration of ethanol Biochem Biophys Res Commun 213 1995 815 819
16. P Lettéron G Labbe C Degott A Berson B Fromenty M Delaforge D Larrey D Pessayre Mechanism for the protective effects of silymarin against carbon tetrachloride–induced lipid peroxidation and hepatotoxicity in mice. Evidence that silymarin acts both as an inhibitor of metabolic activation and as a chain-breaking antioxidant Biochem Pharmacol 39 1990 2027 2034
17. P Lettéron V Duchatelle A Berson B Fromenty C Fisch C Degott JP Benhamou D Pessayre Increased ethane exhalation, an in vivo index of lipid peroxidation, in alcohol-abusers Gut 34 1993 409 414
18. S Cheng Y Chen JA Monforte R Higuchi B Van Houten Template integrity is essential for PCR amplification of 20- to 30-kb sequences from genomic DNA PCR Methods Appl 4 1995 294 298
19. P Chomczynski N Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction Anal Biochem 162 1987 156 159
20. J Sambrook EF Fritsch T. Maniatis 2nd ed Molecular cloning: a laboratory manual 7 1989 Cold Spring Harbor Laboratory Cold Spring Harbor, NY 37-9.62
21. MJ Bibb RA Van Etten CT Wright MW Walberg DA Clayton Sequence and gene organization of mouse mitochondrial DNA Cell 26 1981 167 180
22. 0t-1 probe DNA for the detection of low levels of DNA fragmentation Biochem Cell Biol 72 1994 649 653
23. PH Johnson LI Grossman Electrophoresis of DNA in agarose gels. Optimizing separations of conformational isomers of double- and single-stranded DNAs Biochemistry 16 1977 4217 4225
24. B Fromenty C Fisch G Labbe C Degott D Deshamps A Berson P Lettéron D Pessayre Amiodarone inhibits the mitochondrial β-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice J Pharmacol Exp Ther 255 1990 1371 1376
25. B Fromenty C Fisch A Berson P Lettéron D Larrey D Pessayre Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II J Pharmacol Exp Ther 255 1990 1377 1384
26. D Fau M Lekehal G Farrell A Moreau C Moulis G Feldmann D Haouzi D Pessayre Diterpenoids from germander, an herbal medicine, induce apoptosis in isolated rat hepatocytes Gastroenterology 113 1997 1334 1346
27. TK Palva ET Palva Rapid isolation of animal mitochondrial DNA by alkaline extraction FEBS Lett 192 1985 267 270
28. DP Kalinowski S Illenye B Van Houten Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay Nucleic Acids Res 20 1992 3485 3494
29. MF Denissenko S Venkatachalam EF Yamasaki AA Wani Assessment of DNA damage and repair in specific genomic regions by quantitative immuno-coupled PCR Nucleic Acids Res 22 1994 2351 2359
30. JD Domena DW Mosbaugh Purification of nuclear and mitochondrial uracil-DNA glycosylase from rat liver. Identification of two distinct subcellular forms Biochemistry 24 1985 7320 7328
31. DL Croteau VA Bohr Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells J Biol Chem 272 1997 25409 25412
32. T Lindahl A Andersson Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid Biochemistry 11 1972 3618 3623
33. PR Strauss WA Beard TA Patterson SH Wilson Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs–Haldane mechanism J Biol Chem 272 1997 1302 1307
34. RM Schaaper TA Kunkel LA Loeb Infidelity of DNA synthesis associated with bypass of apurinic sites Proc Natl Acad Sci USA 80 1983 487 491
35. JM Clark Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases Nucleic Acids Res 16 1988 9677 9686
36. ACM Stewart PE Gravitt S Cheng CM Wheeler Generation of entire human papillomavirus genomes by long PCR: frequency of errors produced during amplification Genome Res 5 1995 79 88
37. KS Bhat NK Bhat GR Kulkarni A Iyengar NG Avadhani Expression of the cytochrome b-URF6-URF5 region of the mouse mitochondrial genome Biochemistry 24 1985 5818 5825
38. R Gelfand G Attardi Synthesis and turnover of mitochondrial ribonucleic acid in HeLa cells: the mature ribosomal and messenger ribonucleic acid species are metabolically unstable Mol Cell Biol 1 1981 497 511
39. JF Hare R Hodges Turnover of mitochondrial inner membrane proteins in hepatoma monolayer cultures J Biol Chem 257 1982 3575 3580
40. LA Clejan AI Cederbaum Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1 Biochim Biophys Acta 1034 1990 233 237
41. D Melchiorri RJ Reiter E Sewerynek M Hara L Chen G Nistico Paraquat toxicity and oxidative damage. Reduction by melatonin Biochem Pharmacol 51 1996 1095 1099
42. RJ Reiter Antioxidant actions of melatonin Adv Pharmacol 38 1997 103 107
43. + and alcohol dehydrogenase Alcohol Clin Exp Res 14 1990 238 244
44. E Kukielka E Dicker AI Cederbaum Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment Arch Biochem Biophys 309 1994 377 386
45. SM Bailey CC Cunningham Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated hepatocytes Hepatology 28 1998 1318 1326
46. S Vamvakas EH Vock WK Lutz On the role of DNA double-strand breaks in toxicity and carcinogenesis Crit Rev Toxicol 27 1997 155 174
47. R Drouin H Rodriguez SW Gao Z Gebreyes TR O'Connor GP Holmquist SA Akman Cupric ion/ascorbate/hydrogen peroxide–induced DNA damage: DNA-bound copper ion primarily induces base modifications Free Radic Biol Med 21 1996 261 273
48. TYK Chow MJ Fraser Purification and properties of single strand DNA-binding endo-exonuclease of Neurospora crassa J Biol Chem 258 1983 12010 12018
49. S Ikeda K Ozaki Action of mitochondrial endonuclease G on DNA damaged by L-ascorbic acid, peplomycin, and cis-diamminedichloroplatinum (II) Biochem Biophys Res Commun 235 1997 291 294
50. PS Kingma AH Corbett PC Burcham LJ Marnett N Osheroff Abasic sites stimulate double-stranded DNA cleavage mediated by topoisomerase II. DNA lesions as endogenous topoisomerase II poisons J Biol Chem 270 1995 21441 21444
51. B Thyagarajan RA Padua C Campbell Mammalian mitochondria possess homologous DNA recombination activity J Biol Chem 271 1996 27536 27543
52. JM Shoffner MT Lott AS Voljavec SA Soueidan DA Costigan DC Wallace Spontaneous Kearns–Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy Proc Natl Acad Sci USA 86 1989 7952 7956