-
1
-
-
0013997879
-
Atherosclerosis in relation to the structure and function of the arterial intima, with special reference to the endothelium
-
French, J. E. 1966. Atherosclerosis in relation to the structure and function of the arterial intima, with special reference to the endothelium. Int. Rev. Exp. Pathol. 5: 253-353.
-
(1966)
Int. Rev. Exp. Pathol.
, vol.5
, pp. 253-353
-
-
French, J.E.1
-
2
-
-
0029583514
-
The intima: Development and monoclonal responses to injury
-
Schwartz, S. M., M. W. Majesky, and C. E. Murry. 1995. The intima: development and monoclonal responses to injury. Atherosclerosis. 118 (Suppl): S125-S140.
-
(1995)
Atherosclerosis
, vol.118
, pp. S125-S140
-
-
Schwartz, S.M.1
Majesky, M.W.2
Murry, C.E.3
-
3
-
-
0029098078
-
The intima. Soil for atherosclerosis and restenosis
-
Schwartz, S. M., D. deBlois, and E. R. O'Brien. 1995. The intima. Soil for atherosclerosis and restenosis. Circ. Res. 77: 445-465.
-
(1995)
Circ. Res.
, vol.77
, pp. 445-465
-
-
Schwartz, S.M.1
Deblois, D.2
O'Brien, E.R.3
-
4
-
-
33746003585
-
The absence of lymphatics in normal and atherosclerotic coronary arteries in man: A morphologic study
-
Eliska, O., M. Eliskova, and A. J. Miller. 2006. The absence of lymphatics in normal and atherosclerotic coronary arteries in man: a morphologic study. Lymphology. 39: 76-83.
-
(2006)
Lymphology
, vol.39
, pp. 76-83
-
-
Eliska, O.1
Eliskova, M.2
Miller, A.J.3
-
5
-
-
1642536758
-
Noninvasive measurement of microvascular and interstitial oxygen profi les in a human tumor in SCID mice
-
Torres Filho, I. P., M. Leunig, F. Yuan, M. Intaglietta, and R. K. Jain. 1994. Noninvasive measurement of microvascular and interstitial oxygen profi les in a human tumor in SCID mice. Proc. Natl. Acad. Sci. USA. 91: 2081-2085.
-
(1994)
Proc. Natl. Acad. Sci. USA.
, vol.91
, pp. 2081-2085
-
-
Torres Filho, I.P.1
Leunig, M.2
Yuan, F.3
Intaglietta, M.4
Jain, R.K.5
-
7
-
-
73349141136
-
The role of hypoxia in atherosclerosis
-
Hultén, L. M., and M. Levin. 2009. The role of hypoxia in atherosclerosis. Curr. Opin. Lipidol. 20: 409-414.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 409-414
-
-
Hultén, L.M.1
Levin, M.2
-
8
-
-
84885377829
-
The Warburg effect then and now: From cancer to infl ammatory diseases
-
Palsson-McDermott, E. M., and L. A. O'Neill. 2013. The Warburg effect then and now: from cancer to infl ammatory diseases. BioEssays. 35: 965-973.
-
(2013)
BioEssays.
, vol.35
, pp. 965-973
-
-
Palsson-Mcdermott, E.M.1
O'Neill, L.A.2
-
9
-
-
77952555680
-
Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor
-
Perez, J., B. G. Hill, G. A. Benavides, B. P. Dranka, and V. M. Darley-Usmar. 2010. Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor. Biochem. J. 428: 255-267.
-
(2010)
Biochem. J.
, vol.428
, pp. 255-267
-
-
Perez, J.1
Hill, B.G.2
Benavides, G.A.3
Dranka, B.P.4
Darley-Usmar, V.M.5
-
11
-
-
0015089140
-
Synovial fl uid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases
-
Treuhaft, P. S., and D. J. McCarty. 1971. Synovial fl uid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases. Arthritis Rheum. 14: 475-484.
-
(1971)
Arthritis Rheum.
, vol.14
, pp. 475-484
-
-
Treuhaft, P.S.1
McCarty, D.J.2
-
12
-
-
0013875151
-
Measurement of synovial fl uid pH in normal and arthritic knees
-
Cummings, N. A., and G. L. Nordby. 1966. Measurement of synovial fl uid pH in normal and arthritic knees. Arthritis Rheum. 9 : 47-56.
-
(1966)
Arthritis Rheum.
, vol.9
, pp. 47-56
-
-
Cummings, N.A.1
Nordby, G.L.2
-
13
-
-
0021832906
-
Signifi cance of the hydrogen ion concentration in synovial fl uid in rheumatoid arthritis
-
Farr, M., K. Garvey, A. M. Bold, M. J. Kendall, and P. A. Bacon. 1985. Signifi cance of the hydrogen ion concentration in synovial fl uid in rheumatoid arthritis. Clin. Exp. Rheumatol. 3: 99-104.
-
(1985)
Clin. Exp. Rheumatol.
, vol.3
, pp. 99-104
-
-
Farr, M.1
Garvey, K.2
Bold, A.M.3
Kendall, M.J.4
Bacon, P.A.5
-
14
-
-
0035071662
-
The effects of extracellular pH on immune function
-
Lardner, A. 2001. The effects of extracellular pH on immune function. J. Leukoc. Biol. 69: 522-530.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 522-530
-
-
Lardner, A.1
-
15
-
-
84882793920
-
Regulation of infl ammation by extracellular acidifi cation and proton-sensing GPCRs
-
Okajima, F. 2013. Regulation of infl ammation by extracellular acidifi cation and proton-sensing GPCRs. Cell. Signal. 25 : 2263-2271.
-
(2013)
Cell. Signal.
, vol.25
, pp. 2263-2271
-
-
Okajima, F.1
-
16
-
-
78649713698
-
Physiological roles of voltage-gated proton channels in leukocytes
-
Demaurex, N., and A. El Chemaly. 2010. Physiological roles of voltage-gated proton channels in leukocytes. J. Physiol. 588 : 4659-4665.
-
(2010)
J. Physiol.
, vol.588
, pp. 4659-4665
-
-
Demaurex, N.1
El Chemaly, A.2
-
17
-
-
84862210687
-
Voltage-gated proton channels
-
Decoursey, T. E. 2012. Voltage-gated proton channels. Compr. Physiol. 2: 1355-1385.
-
(2012)
Compr. Physiol.
, vol.2
, pp. 1355-1385
-
-
Decoursey, T.E.1
-
18
-
-
43549108978
-
Acidifi cation enhances peritoneal macrophage phagocytic activity
-
Grabowski, J. E., V. L. Vega, M. A. Talamini, and A. De Maio. 2008. Acidifi cation enhances peritoneal macrophage phagocytic activity. J. Surg. Res. 147: 206-211.
-
(2008)
J. Surg. Res.
, vol.147
, pp. 206-211
-
-
Grabowski, J.E.1
Vega, V.L.2
Talamini, M.A.3
De Maio, A.4
-
19
-
-
84874457095
-
Extracellular acidosis modulates the endocytosis and maturation of macrophages
-
Kong, X., X. Tang, W. Du, J. Tong, Y. Yan, F. Zheng, M. Fang , F. Gong, and Z. Tan. 2013. Extracellular acidosis modulates the endocytosis and maturation of macrophages. Cell. Immunol. 281 : 44-50.
-
(2013)
Cell. Immunol.
, vol.281
, pp. 44-50
-
-
Kong, X.1
Tang, X.2
Du, W.3
Tong, J.4
Yan, Y.5
Zheng, F.6
Fang, M.7
Gong, F.8
Tan, Z.9
-
20
-
-
10744231358
-
Acidosis improves uptake of antigens and MHC class I-restricted presentation by dendritic cells
-
Vermeulen, M., M. Giordano, A. S. Trevani, C. Sedlik, R. Gamberale, P. Fernandez-Calotti, G. Salamone, S. Raiden, J. Sanjurjo, and J. R. Geffner. 2004. Acidosis improves uptake of antigens and MHC class I-restricted presentation by dendritic cells. J. Immunol. 172: 3196-3204.
-
(2004)
J. Immunol.
, vol.172
, pp. 3196-3204
-
-
Vermeulen, M.1
Giordano, M.2
Trevani, A.S.3
Sedlik, C.4
Gamberale, R.5
Fernandez-Calotti, P.6
Salamone, G.7
Raiden, S.8
Sanjurjo, J.9
Geffner, J.R.10
-
21
-
-
84903543514
-
Cysteine cathepsins and extracellular matrix degradation
-
Fonović, M., and B. Turk. 2014. Cysteine cathepsins and extracellular matrix degradation. Biochim. Biophys. Acta. 1840: 2560-2570.
-
(2014)
Biochim. Biophys. Acta.
, vol.1840
, pp. 2560-2570
-
-
Fonović, M.1
Turk, B.2
-
22
-
-
0035996576
-
PH Heterogeneity of human and rabbit atherosclerotic plaques; A new insight into detection of vulnerable plaque
-
Naghavi, M., R. John, S. Naguib, M. S. Siadaty, R. Grasu, K. C. Kurian, W. B. van Winkle, B. Soller, S. Litovsky, M. Madjid , et al. 2002. pH Heterogeneity of human and rabbit atherosclerotic plaques; a new insight into detection of vulnerable plaque. Atherosclerosis. 164: 27-35.
-
(2002)
Atherosclerosis
, vol.164
, pp. 27-35
-
-
Naghavi, M.1
John, R.2
Naguib, S.3
Siadaty, M.S.4
Grasu, R.5
Kurian, K.C.6
Van Winkle, W.B.7
Soller, B.8
Litovsky, S.9
Madjid, M.10
-
23
-
-
0017089008
-
Hypoxiadependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo
-
Varghese, A. J., S. Gulyas, and J. K. Mohindra. 1976. Hypoxiadependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo. Cancer Res. 36: 3761-3765.
-
(1976)
Cancer Res.
, vol.36
, pp. 3761-3765
-
-
Varghese, A.J.1
Gulyas, S.2
Mohindra, J.K.3
-
24
-
-
0029012868
-
Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids
-
Gross, M. W., U. Karbach, K. Groebe, A. J. Franko, and W. Mueller-Klieser. 1995. Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids. Int. J. Cancer. 61: 567-573.
-
(1995)
Int. J. Cancer.
, vol.61
, pp. 567-573
-
-
Gross, M.W.1
Karbach, U.2
Groebe, K.3
Franko, A.J.4
Mueller-Klieser, W.5
-
25
-
-
40849086607
-
Hypoxia, hypoxiainducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis
-
Sluimer, J. C., J. M. Gasc, J. L. van Wanroij, N. Kisters, M. Groeneweg, M. D. Sollewijn Gelpke, J. P. Cleutjens, L. H. van den Akker, P. Corvol, B. G. Wouters, et al. 2008. Hypoxia, hypoxiainducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J. Am. Coll. Cardiol. 51: 1258-1265.
-
(2008)
J. Am. Coll. Cardiol.
, vol.51
, pp. 1258-1265
-
-
Sluimer, J.C.1
Gasc, J.M.2
Van Wanroij, J.L.3
Kisters, N.4
Groeneweg, M.5
Sollewijn Gelpke, M.D.6
Cleutjens, J.P.7
Den Van Akker, L.H.8
Corvol, P.9
Wouters, B.G.10
-
26
-
-
33748086766
-
ATP depletion in macrophages in the core of advanced rabbit atherosclerotic plaques in vivo
-
Leppänen, O., T. Björnheden, M. Evaldsson, J. Boren, O. Wiklund , and M. Levin. 2006. ATP depletion in macrophages in the core of advanced rabbit atherosclerotic plaques in vivo. Atherosclerosis. 188: 323-330.
-
(2006)
Atherosclerosis
, vol.188
, pp. 323-330
-
-
Leppänen, O.1
Björnheden, T.2
Evaldsson, M.3
Boren, J.4
Wiklund, O.5
Levin, M.6
-
27
-
-
84872576236
-
Metabolism of infl ammation limited by AMPK and pseudo-starvation
-
O'Neill, L. A., and D. G. Hardie. 2013. Metabolism of infl ammation limited by AMPK and pseudo-starvation. Nature. 493 : 346-355.
-
(2013)
Nature
, vol.493
, pp. 346-355
-
-
O'Neill, L.A.1
Hardie, D.G.2
-
28
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg, O. 1956. On respiratory impairment in cancer cells. Science. 124: 269-270.
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
31
-
-
77956213727
-
Substrate fate in activated macrophages: A comparison between innate, classic, and alternative activation
-
Rodríguez-Prados, J. C., P. G. Traves, J. Cuenca, D. Rico, J. Aragones, P. Martin-Sanz, M. Cascante, and L. Bosca. 2010. Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation. J. Immunol. 185: 605-614.
-
(2010)
J. Immunol.
, vol.185
, pp. 605-614
-
-
Rodríguez-Prados, J.C.1
Traves, P.G.2
Cuenca, J.3
Rico, D.4
Aragones, J.5
Martin-Sanz, P.6
Cascante, M.7
Bosca, L.8
-
32
-
-
0037423948
-
HIF-1alpha is essential for myeloid cell-mediated infl ammation
-
Cramer, T., Y. Yamanishi, B. E. Clausen, I. Forster, R. Pawlinski, N. Mackman, V. H. Haase, R. Jaenisch, M. Corr, V. Nizet, et al. 2003. HIF-1alpha is essential for myeloid cell-mediated infl ammation. Cell. 112: 645-657.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
-
33
-
-
67649207249
-
Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions
-
Roiniotis, J., H. Dinh, P. Masendycz, A. Turner, C. L. Elsegood , G. M. Scholz, and J. A. Hamilton. 2009. Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions. J. Immunol. 182 : 7974-7981.
-
(2009)
J. Immunol.
, vol.182
, pp. 7974-7981
-
-
Roiniotis, J.1
Dinh, H.2
Masendycz, P.3
Turner, A.4
Elsegood, C.L.5
Scholz, G.M.6
Hamilton, J.A.7
-
34
-
-
77954735369
-
Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
-
Krawczyk, C. M., T. Holowka, J. Sun, J. Blagih, E. Amiel, R. J. DeBerardinis, J. R. Cross, E. Jung, C. B. Thompson, R. G. Jones, et al. 2010. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115: 4742-4749.
-
(2010)
Blood
, vol.115
, pp. 4742-4749
-
-
Krawczyk, C.M.1
Holowka, T.2
Sun, J.3
Blagih, J.4
Amiel, E.5
Deberardinis, R.J.6
Cross, J.R.7
Jung, E.8
Thompson, C.B.9
Jones, R.G.10
-
35
-
-
0035966119
-
Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes
-
Lukashev, D., C. Caldwell, A. Ohta, P. Chen, and M. Sitkovsky. 2001. Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes. J. Biol. Chem. 276: 48754-48763.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48754-48763
-
-
Lukashev, D.1
Caldwell, C.2
Ohta, A.3
Chen, P.4
Sitkovsky, M.5
-
36
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West, A. P., I. E. Brodsky, C. Rahner, D. K. Woo, H. Erdjument-Bromage, P. Tempst, M. C. Walsh, Y. Choi, G. S. Shadel, and S. Ghosh. 2011. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature. 472: 476-480.
-
(2011)
Nature
, vol.472
, pp. 476-480
-
-
West, A.P.1
Brodsky, I.E.2
Rahner, C.3
Woo, D.K.4
Erdjument-Bromage, H.5
Tempst, P.6
Walsh, M.C.7
Choi, Y.8
Shadel, G.S.9
Ghosh, S.10
-
37
-
-
0003178016
-
Biology of infl ammation; Chemical mediators and cellular injury
-
Menkin, V. 1956. Biology of infl ammation; chemical mediators and cellular injury. Science. 123: 527-534.
-
(1956)
Science
, vol.123
, pp. 527-534
-
-
Menkin, V.1
-
38
-
-
84877705901
-
Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 infl ammasome
-
Rajamäki, K., T. Nordström, K. Nurmi, K. E. Akerman, P. T. Kovanen, K. Öörni, and K. K. Eklund. 2013. Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 infl ammasome. J. Biol. Chem. 288: 13410-13419.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 13410-13419
-
-
Rajamäki, K.1
Nordström, T.2
Nurmi, K.3
Akerman, K.E.4
Kovanen, P.T.5
Öörni, K.6
Eklund, K.K.7
-
39
-
-
0032752588
-
Acidic pH increases the avidity of FcgammaR for immune complexes
-
López, D. H., A. S. Trevani, G. Salamone, G. Andonegui, S. Raiden, M. Giordano, and J. R. Geffner. 1999. Acidic pH increases the avidity of FcgammaR for immune complexes. Immunology. 98 : 450-455.
-
(1999)
Immunology.
, vol.98
, pp. 450-455
-
-
López, D.H.1
Trevani, A.S.2
Salamone, G.3
Andonegui, G.4
Raiden, S.5
Giordano, M.6
Geffner, J.R.7
-
40
-
-
84859510048
-
Extracellular low pH modulates phosphatidylserine-dependent phagocytosis in macrophages by increasing stabilin-1 expression
-
Park, S. Y., D. J. Bae, M. J. Kim, M. L. Piao, and I. S. Kim. 2012. Extracellular low pH modulates phosphatidylserine-dependent phagocytosis in macrophages by increasing stabilin-1 expression. J. Biol. Chem. 287: 11261-11271.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 11261-11271
-
-
Park, S.Y.1
Bae, D.J.2
Kim, M.J.3
Piao, M.L.4
Kim, I.S.5
-
41
-
-
0025039572
-
Modulation of the macrophage respiratory burst by an acidic environment: The critical role of cytoplasmic pH regulation by proton extrusion pumps
-
discussion 368-369
-
Swallow, C. J., S. Grinstein, R. A. Sudsbury, and O. D. Rotstein. 1990. Modulation of the macrophage respiratory burst by an acidic environment: the critical role of cytoplasmic pH regulation by proton extrusion pumps. Surgery. 108: 363-368; discussion 368-369.
-
(1990)
Surgery.
, vol.108
, pp. 363-368
-
-
Swallow, C.J.1
Grinstein, S.2
Sudsbury, R.A.3
Rotstein, O.D.4
-
42
-
-
0034098221
-
Bactericidal activity of alveolar macrophages is suppressed by V-ATPase inhibition
-
Bidani, A., B. S. Reisner, A. K. Haque, J. Wen, R. E. Helmer, D. M. Tuazon, and T. A. Heming. 2000. Bactericidal activity of alveolar macrophages is suppressed by V-ATPase inhibition. Lung. 178: 91-104.
-
(2000)
Lung.
, vol.178
, pp. 91-104
-
-
Bidani, A.1
Reisner, B.S.2
Haque, A.K.3
Wen, J.4
Helmer, R.E.5
Tuazon, D.M.6
Heming, T.A.7
-
43
-
-
0021351203
-
Oxygen toxicity, oxygen radicals, transition metals and disease
-
Halliwell, B., and J. M. Gutteridge. 1984. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 219: 1-14.
-
(1984)
Biochem. J.
, vol.219
, pp. 1-14
-
-
Halliwell, B.1
Gutteridge, J.M.2
-
44
-
-
0027524539
-
Acidic pH increases the oxidation of LDL by macrophages
-
Morgan, J., and D. S. Leake. 1993. Acidic pH increases the oxidation of LDL by macrophages. FEBS Lett. 333: 275-279.
-
(1993)
FEBS Lett.
, vol.333
, pp. 275-279
-
-
Morgan, J.1
Leake, D.S.2
-
45
-
-
0032570596
-
Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation
-
Bellocq, A., S. Suberville, C. Philippe, F. Bertrand, J. Perez, B. Fouqueray, G. Cherqui, and L. Baud. 1998. Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation. J. Biol. Chem. 273: 5086-5092.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5086-5092
-
-
Bellocq, A.1
Suberville, S.2
Philippe, C.3
Bertrand, F.4
Perez, J.5
Fouqueray, B.6
Cherqui, G.7
Baud, L.8
-
46
-
-
84857058393
-
Tumor necrosis factor expression is ameliorated after exposure to an acidic environment
-
Grabowski, J., D. E. Vazquez, T. Costantini, D. M. Cauvi, W. Charles, S. Bickler, M. A. Talamini, V. L. Vega, R. Coimbra, and A. De Maio. 2012. Tumor necrosis factor expression is ameliorated after exposure to an acidic environment. J. Surg. Res. 173: 127-134.
-
(2012)
J. Surg. Res.
, vol.173
, pp. 127-134
-
-
Grabowski, J.1
Vazquez, D.E.2
Costantini, T.3
Cauvi, D.M.4
Charles, W.5
Bickler, S.6
Talamini, M.A.7
Vega, V.L.8
Coimbra, R.9
De Maio, A.10
-
47
-
-
0034854585
-
Effects of extracellular pH on tumour necrosis factor-alpha production by resident alveolar macrophages
-
Heming, T. A., S. K. Dave, D. M. Tuazon, A. K. Chopra, J. W. Peterson, and A. Bidani. 2001. Effects of extracellular pH on tumour necrosis factor-alpha production by resident alveolar macrophages. Clin. Sci. (Lond.). 101: 267-274.
-
(2001)
Clin. Sci. (Lond.).
, vol.101
, pp. 267-274
-
-
Heming, T.A.1
Dave, S.K.2
Tuazon, D.M.3
Chopra, A.K.4
Peterson, J.W.5
Bidani, A.6
-
48
-
-
64849099960
-
Involvement of proton-sensing TDAG8 in extracellular acidifi cation-induced inhibition of proinfl ammatory cytokine production in peritoneal macrophages
-
Mogi, C., M. Tobo, H. Tomura, N. Murata, X. D. He, K. Sato, T. Kimura, T. Ishizuka, T. Sasaki, T. Sato, et al. 2009. Involvement of proton-sensing TDAG8 in extracellular acidifi cation-induced inhibition of proinfl ammatory cytokine production in peritoneal macrophages. J. Immunol. 182: 3243-3251.
-
(2009)
J. Immunol.
, vol.182
, pp. 3243-3251
-
-
Mogi, C.1
Tobo, M.2
Tomura, H.3
Murata, N.4
He, X.D.5
Sato, K.6
Kimura, T.7
Ishizuka, T.8
Sasaki, T.9
Sato, T.10
-
49
-
-
84896291248
-
Effect of low extracellular pH on NF-kappaB activation in macrophages
-
Gerry, A. B., and D. S. Leake. 2014. Effect of low extracellular pH on NF-kappaB activation in macrophages. Atherosclerosis. 233 : 537-544.
-
(2014)
Atherosclerosis
, vol.233
, pp. 537-544
-
-
Gerry, A.B.1
Leake, D.S.2
-
50
-
-
84855451921
-
Low extracellular pH stimulates the production of IL-1beta by human monocytes
-
Jancic, C. C., M. Cabrini, M. L. Gabelloni, C. Rodriguez Rodrigues , G. Salamone, A. S. Trevani, and J. Geffner. 2012. Low extracellular pH stimulates the production of IL-1beta by human monocytes. Cytokine. 57: 258-268.
-
(2012)
Cytokine
, vol.57
, pp. 258-268
-
-
Jancic, C.C.1
Cabrini, M.2
Gabelloni, M.L.3
Rodriguez Rodrigues, C.4
Salamone, G.5
Trevani, A.S.6
Geffner, J.7
-
51
-
-
64049084303
-
Differential requirement for the activation of the infl ammasome for processing and release of IL- 1beta in monocytes and macrophages
-
Netea, M. G., C. A. Nold-Petry, M. F. Nold, L. A. Joosten, B. Opitz, J. H. van der Meer, F. L. van de Veerdonk, G. Ferwerda, B. Heinhuis, I. Devesa, et al. 2009. Differential requirement for the activation of the infl ammasome for processing and release of IL- 1beta in monocytes and macrophages. Blood. 113: 2324-2335.
-
(2009)
Blood
, vol.113
, pp. 2324-2335
-
-
Netea, M.G.1
Nold-Petry, C.A.2
Nold, M.F.3
Joosten, L.A.4
Opitz, B.5
Meer Der Van, J.H.6
Veerdonk De Van, F.L.7
Ferwerda, G.8
Heinhuis, B.9
Devesa, I.10
-
52
-
-
77951800951
-
NLRP3 infl ammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell, P., H. Kono, K. J. Rayner, C. M. Sirois, G. Vladimer, F. G. Bauernfeind, G. S. Abela, L. Franchi, G. Nunez, M. Schnurr, et al. 2010. NLRP3 infl ammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 464: 1357-1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
-
53
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 infl ammasome in human macrophages: A novel link between cholesterol metabolism and infl ammation
-
Rajamäki, K., J. Lappalainen, K. Öörni, E. Valimaki, S. Matikainen , P. T. Kovanen, and K. K. Eklund. 2010. Cholesterol crystals activate the NLRP3 infl ammasome in human macrophages: a novel link between cholesterol metabolism and infl ammation. PLoS ONE. 5: e11765.
-
(2010)
PLoS ONE.
, vol.5
, pp. e11765
-
-
Rajamäki, K.1
Lappalainen, J.2
Öörni, K.3
Valimaki, E.4
Matikainen, S.5
Kovanen, P.T.6
Eklund, K.K.7
-
54
-
-
84876694486
-
Identifi cation of macrophage genes responsive to extracellular acidifi cation
-
Park, S. Y., and I. S. Kim. 2013. Identifi cation of macrophage genes responsive to extracellular acidifi cation. Infl amm. Res. 62 : 399-406.
-
(2013)
Infl Amm. Res.
, vol.62
, pp. 399-406
-
-
Park, S.Y.1
Kim, I.S.2
-
55
-
-
84886645705
-
Pathogenic role of modifi ed LDL antibodies and immune complexes in atherosclerosis
-
Lopes-Virella, M. F., and G. Virella. 2013. Pathogenic role of modifi ed LDL antibodies and immune complexes in atherosclerosis. J. Atheroscler. Thromb. 20: 743-754.
-
(2013)
J. Atheroscler. Thromb.
, vol.20
, pp. 743-754
-
-
Lopes-Virella, M.F.1
Virella, G.2
-
56
-
-
62649139025
-
Immunological and infl ammatory functions of the interleukin-1 family
-
Dinarello, C. A. 2009. Immunological and infl ammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27: 519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
57
-
-
0031877416
-
Association of apo B lipoproteins with arterial proteoglycans: Pathological signifi cance and molecular basis
-
Camejo, G., E. Hurt-Camejo, O. Wiklund, and G. Bondjers. 1998. Association of apo B lipoproteins with arterial proteoglycans: pathological signifi cance and molecular basis. Atherosclerosis. 139 : 205-222.
-
(1998)
Atherosclerosis
, vol.139
, pp. 205-222
-
-
Camejo, G.1
Hurt-Camejo, E.2
Wiklund, O.3
Bondjers, G.4
-
58
-
-
0037071843
-
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
-
Skalén, K., M. Gustafsson, E. K. Rydberg, L. M. Hulten, O. Wiklund, T. L. Innerarity, and J. Boren. 2002. Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature. 417: 750-754.
-
(2002)
Nature
, vol.417
, pp. 750-754
-
-
Skalén, K.1
Gustafsson, M.2
Rydberg, E.K.3
Hulten, L.M.4
Wiklund, O.5
Innerarity, T.L.6
Boren, J.7
-
59
-
-
0029299438
-
The response-to-retention hypothesis of early atherogenesis
-
Williams, K. J., and I. Tabas. 1995. The response-to-retention hypothesis of early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 15 : 551-561.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 551-561
-
-
Williams, K.J.1
Tabas, I.2
-
60
-
-
37349021003
-
Subendothelial lipoprotein retention as the initiating process in atherosclerosis: Update and therapeutic implications
-
Tabas, I., K. J. Williams, and J. Boren. 2007. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation. 116: 1832-1844.
-
(2007)
Circulation.
, vol.116
, pp. 1832-1844
-
-
Tabas, I.1
Williams, K.J.2
Boren, J.3
-
61
-
-
0030595998
-
Isolation and characterization of a proteoglycan variant from human aorta exhibiting a marked affi nity for low density lipoprotein and demonstration of its enhanced expression in atherosclerotic plaques
-
Vijayagopal, P., J. E. Figueroa, J. D. Fontenot, and D. L. Glancy. 1996. Isolation and characterization of a proteoglycan variant from human aorta exhibiting a marked affi nity for low density lipoprotein and demonstration of its enhanced expression in atherosclerotic plaques. Atherosclerosis. 127: 195-203.
-
(1996)
Atherosclerosis
, vol.127
, pp. 195-203
-
-
Vijayagopal, P.1
Figueroa, J.E.2
Fontenot, J.D.3
Glancy, D.L.4
-
62
-
-
0027210886
-
Binding of low density lipoproteins by proteoglycans synthesized by proliferating and quiescent human arterial smooth muscle cells
-
Camejo, G., G. Fager, B. Rosengren, E. Hurt-Camejo, and G. Bondjers. 1993. Binding of low density lipoproteins by proteoglycans synthesized by proliferating and quiescent human arterial smooth muscle cells. J. Biol. Chem. 268: 14131-14137.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14131-14137
-
-
Camejo, G.1
Fager, G.2
Rosengren, B.3
Hurt-Camejo, E.4
Bondjers, G.5
-
63
-
-
0031472257
-
Interaction of very-low-density, intermediate-density, and low-density lipoproteins with human arterial wall proteoglycans
-
Anber, V., J. S. Millar, M. McConnell, J. Shepherd, and C. J. Packard. 1997. Interaction of very-low-density, intermediate-density, and low-density lipoproteins with human arterial wall proteoglycans. Arterioscler. Thromb. Vasc. Biol. 17: 2507-2514.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 2507-2514
-
-
Anber, V.1
Millar, J.S.2
McConnell, M.3
Shepherd, J.4
Packard, C.J.5
-
64
-
-
0037200065
-
Identifi cation of the proteoglycan binding site in apolipoprotein B48
-
Flood, C., M. Gustafsson, P. E. Richardson, S. C. Harvey, J. P. Segrest, and J. Boren. 2002. Identifi cation of the proteoglycan binding site in apolipoprotein B48. J. Biol. Chem. 277 : 32228-32233.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32228-32233
-
-
Flood, C.1
Gustafsson, M.2
Richardson, P.E.3
Harvey, S.C.4
Segrest, J.P.5
Boren, J.6
-
65
-
-
0036773865
-
Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis
-
Proctor, S. D., D. F. Vine, and J. C. Mamo. 2002. Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis. Curr. Opin. Lipidol. 13: 461-470.
-
(2002)
Curr. Opin. Lipidol.
, vol.13
, pp. 461-470
-
-
Proctor, S.D.1
Vine, D.F.2
Mamo, J.C.3
-
66
-
-
0028172762
-
Triglyceride-rich lipoproteins isolated by selected-affi nity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
-
Rapp, J. H., A. Lespine, R. L. Hamilton, N. Colyvas, A. H. Chaumeton, J. Tweedie-Hardman, L. Kotite, S. T. Kunitake, R. J. Havel, and J. P. Kane. 1994. Triglyceride-rich lipoproteins isolated by selected-affi nity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler. Thromb. 14: 1767-1774.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 1767-1774
-
-
Rapp, J.H.1
Lespine, A.2
Hamilton, R.L.3
Colyvas, N.4
Chaumeton, A.H.5
Tweedie-Hardman, J.6
Kotite, L.7
Kunitake, S.T.8
Havel, R.J.9
Kane, J.P.10
-
67
-
-
79953748675
-
Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: Concordance and discordance with cardiovascular disease risk
-
Nordestgaard, B. G., and A. Tybjaerg-Hansen. 2011. Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk. Curr. Opin. Lipidol. 22: 113-122.
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 113-122
-
-
Nordestgaard, B.G.1
Tybjaerg-Hansen, A.2
-
68
-
-
27844583439
-
Decrease in pH strongly enhances binding of native, proteolyzed, lipolyzed, and oxidized low density lipoprotein particles to human aortic proteoglycans
-
Sneck, M., P. T. Kovanen, and K. Öörni. 2005. Decrease in pH strongly enhances binding of native, proteolyzed, lipolyzed, and oxidized low density lipoprotein particles to human aortic proteoglycans. J. Biol. Chem. 280: 37449-37454.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37449-37454
-
-
Sneck, M.1
Kovanen, P.T.2
Öörni, K.3
-
69
-
-
83455220666
-
Acidity and lipolysis by group v secreted phospholipase A(2) strongly increase the binding of apoB-100-containing lipoproteins to human aortic proteoglycans
-
Lähdesmäki, K., K. Öörni, M. Alanne-Kinnunen, M. Jauhiainen , E. Hurt-Camejo, and P. T. Kovanen. 2012. Acidity and lipolysis by group V secreted phospholipase A(2) strongly increase the binding of apoB-100-containing lipoproteins to human aortic proteoglycans. Biochim. Biophys. Acta. 1821: 257-267.
-
(2012)
Biochim. Biophys. Acta.
, vol.1821
, pp. 257-267
-
-
Lähdesmäki, K.1
Öörni, K.2
Alanne-Kinnunen, M.3
Jauhiainen, M.4
Hurt-Camejo, E.5
Kovanen, P.T.6
-
70
-
-
0018895113
-
Glycosaminoglycans: Structure and interaction
-
Chakrabarti, B., and J. W. Park. 1980. Glycosaminoglycans: structure and interaction. CRC Crit. Rev. Biochem. 8: 225-313.
-
(1980)
CRC Crit. Rev. Biochem.
, vol.8
, pp. 225-313
-
-
Chakrabarti, B.1
Park, J.W.2
-
71
-
-
0030956262
-
Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions?
-
Leake, D. S. 1997. Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions? Atherosclerosis. 129 : 149-157.
-
(1997)
Atherosclerosis
, vol.129
, pp. 149-157
-
-
Leake, D.S.1
-
72
-
-
0027257233
-
Lipoprotein lipase and sphingomyelinase synergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix. A possible mechanism for low density lipoprotein and lipoprotein(a) retention and macrophage foam cell formation
-
Tabas, I., Y. Li, R. W. Brocia, S. W. Xu, T. L. Swenson, and K. J. Williams. 1993. Lipoprotein lipase and sphingomyelinase synergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix. A possible mechanism for low density lipoprotein and lipoprotein(a) retention and macrophage foam cell formation. J. Biol. Chem. 268 : 20419-20432.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20419-20432
-
-
Tabas, I.1
Li, Y.2
Brocia, R.W.3
Xu, S.W.4
Swenson, T.L.5
Williams, K.J.6
-
73
-
-
0039765224
-
Lipoprotein lipase (LPL) strongly links native and oxidized low density lipoprotein particles to decorin-coated collagen. Roles for both dimeric and monomeric forms of LPL
-
Pentikäinen, M. O., K. Öörni, and P. T. Kovanen. 2000. Lipoprotein lipase (LPL) strongly links native and oxidized low density lipoprotein particles to decorin-coated collagen. Roles for both dimeric and monomeric forms of LPL. J. Biol. Chem. 275 : 5694-5701.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5694-5701
-
-
Pentikäinen, M.O.1
Öörni, K.2
Kovanen, P.T.3
-
74
-
-
35448934922
-
Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: Evidence for a role of lipoprotein lipase
-
Gustafsson, M., M. Levin, K. Skalen, J. Perman, V. Friden, P. Jirholt, S. O. Olofsson, S. Fazio, M. F. Linton, C. F. Semenkovich , et al. 2007. Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. Circ. Res. 101: 777-783.
-
(2007)
Circ. Res.
, vol.101
, pp. 777-783
-
-
Gustafsson, M.1
Levin, M.2
Skalen, K.3
Perman, J.4
Friden, V.5
Jirholt, P.6
Olofsson, S.O.7
Fazio, S.8
Linton, M.F.9
Semenkovich, C.F.10
-
75
-
-
0021908539
-
Binding of active and inactive forms of lipoprotein lipase to heparin. Effects of pH
-
Bengtsson-Olivecrona, G., and T. Olivecrona. 1985. Binding of active and inactive forms of lipoprotein lipase to heparin. Effects of pH. Biochem. J. 226: 409-413.
-
(1985)
Biochem. J.
, vol.226
, pp. 409-413
-
-
Bengtsson-Olivecrona, G.1
Olivecrona, T.2
-
76
-
-
0020645675
-
The effects of pH and salt on the lipid binding and enzyme activity of lipoprotein lipase
-
Bengtsson, G., and T. Olivecrona. 1983. The effects of pH and salt on the lipid binding and enzyme activity of lipoprotein lipase. Biochim. Biophys. Acta. 751: 254-259.
-
(1983)
Biochim. Biophys. Acta.
, vol.751
, pp. 254-259
-
-
Bengtsson, G.1
Olivecrona, T.2
-
77
-
-
0033729477
-
Aggregation, fusion, and vesicle formation of modifi ed low density lipoprotein particles: Molecular mechanisms and effects on matrix interactions
-
Öörni, K., M. O. Pentikäinen, M. Ala-Korpela, and P. T. Kovanen. 2000. Aggregation, fusion, and vesicle formation of modifi ed low density lipoprotein particles: molecular mechanisms and effects on matrix interactions. J. Lipid Res. 41: 1703-1714.
-
(2000)
J. Lipid Res.
, vol.41
, pp. 1703-1714
-
-
Öörni, K.1
Pentikäinen, M.O.2
Ala-Korpela, M.3
Kovanen, P.T.4
-
78
-
-
33748575321
-
Enhanced extracellular lipid accumulation in acidic environments
-
Oörni, K., and P. T. Kovanen. 2006. Enhanced extracellular lipid accumulation in acidic environments. Curr. Opin. Lipidol. 17: 534-540.
-
(2006)
Curr. Opin. Lipidol.
, vol.17
, pp. 534-540
-
-
Oörni, K.1
Kovanen, P.T.2
-
79
-
-
4544245056
-
Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifi es low density lipoprotein particles in vitro
-
Oörni, K., M. Sneck, D. Bromme, M. O. Pentikäinen, K. A. Lindstedt, M. Mäyranpää, H. Aitio, and P. T. Kovanen. 2004. Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifi es low density lipoprotein particles in vitro. J. Biol. Chem. 279 : 34776-34784.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34776-34784
-
-
Oörni, K.1
Sneck, M.2
Bromme, D.3
Pentikäinen, M.O.4
Lindstedt, K.A.5
Mäyranpää, M.6
Aitio, H.7
Kovanen, P.T.8
-
80
-
-
0025072226
-
Macrophage proteases can modify low density lipoproteins to increase their uptake by macrophages
-
Leake, D. S., S. M. Rankin, and J. Collard. 1990. Macrophage proteases can modify low density lipoproteins to increase their uptake by macrophages. FEBS Lett. 269: 209-212.
-
(1990)
FEBS Lett.
, vol.269
, pp. 209-212
-
-
Leake, D.S.1
Rankin, S.M.2
Collard, J.3
-
81
-
-
0032145836
-
Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells
-
Sukhova, G. K., G. P. Shi, D. I. Simon, H. A. Chapman, and P. Libby. 1998. Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. J. Clin. Invest. 102: 576-583.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 576-583
-
-
Sukhova, G.K.1
Shi, G.P.2
Simon, D.I.3
Chapman, H.A.4
Libby, P.5
-
82
-
-
77953491246
-
Proteolysis sensitizes LDL particles to phospholipolysis by secretory phospholipase A2 group v and secretory sphingomyelinase
-
Plihtari, R., E. Hurt-Camejo, K. Öörni, and P. T. Kovanen. 2010. Proteolysis sensitizes LDL particles to phospholipolysis by secretory phospholipase A2 group V and secretory sphingomyelinase. J. Lipid Res. 51: 1801-1809.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1801-1809
-
-
Plihtari, R.1
Hurt-Camejo, E.2
Öörni, K.3
Kovanen, P.T.4
-
83
-
-
0042009400
-
Lysosomal enzymes are released from cultured human macrophages, hydrolyze LDL in vitro, and are present extracellularly in human atherosclerotic lesions
-
Hakala, J. K., R. Oksjoki, P. Laine, H. Du, G. A. Grabowski, P. T. Kovanen, and M. O. Pentikainen. 2003. Lysosomal enzymes are released from cultured human macrophages, hydrolyze LDL in vitro, and are present extracellularly in human atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 23: 1430-1436.
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1430-1436
-
-
Hakala, J.K.1
Oksjoki, R.2
Laine, P.3
Du, H.4
Grabowski, G.A.5
Kovanen, P.T.6
Pentikainen, M.O.7
-
84
-
-
0033802292
-
Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-defi cient human macrophages
-
Punturieri, A., S. Filippov, E. Allen, I. Caras, R. Murray, V. Reddy , and S. J. Weiss. 2000. Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-defi cient human macrophages. J. Exp. Med. 192: 789-799.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 789-799
-
-
Punturieri, A.1
Filippov, S.2
Allen, E.3
Caras, I.4
Murray, R.5
Reddy, V.6
Weiss, S.J.7
-
85
-
-
73949150306
-
Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins
-
Haka, A. S., I. Grosheva, E. Chiang, A. R. Buxbaum, B. A. Baird , L. M. Pierini, and F. R. Maxfi eld. 2009. Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins. Mol. Biol. Cell. 20: 4932-4940.
-
(2009)
Mol. Biol. Cell.
, vol.20
, pp. 4932-4940
-
-
Haka, A.S.1
Grosheva, I.2
Chiang, E.3
Buxbaum, A.R.4
Baird, B.A.5
Pierini, L.M.6
Maxfield, F.R.7
-
86
-
-
84881022605
-
Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein
-
Haka, A. S., I. Grosheva, R. K. Singh, and F. R. Maxfi eld. 2013. Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein. Arterioscler. Thromb. Vasc. Biol. 33: 1768-1778.
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 1768-1778
-
-
Haka, A.S.1
Grosheva, I.2
Singh, R.K.3
Maxfield, F.R.4
-
87
-
-
0023972981
-
George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry
-
Small, D. M. 1988. George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry. Arteriosclerosis. 8: 103-129.
-
(1988)
Arteriosclerosis.
, vol.8
, pp. 103-129
-
-
Small, D.M.1
-
88
-
-
0017180029
-
Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques
-
Katz, S. S., G. G. Shipley, and D. M. Small. 1976. Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques. J. Clin. Invest. 58: 200-211.
-
(1976)
J. Clin. Invest.
, vol.58
, pp. 200-211
-
-
Katz, S.S.1
Shipley, G.G.2
Small, D.M.3
-
89
-
-
0027750755
-
Transitional features in human atherosclerosis. Intimal thickening, cholesterol clefts, and cell loss in human aortic fatty streaks
-
Guyton, J. R., and K. F. Klemp. 1993. Transitional features in human atherosclerosis. Intimal thickening, cholesterol clefts, and cell loss in human aortic fatty streaks. Am. J. Pathol. 143: 1444-1457.
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 1444-1457
-
-
Guyton, J.R.1
Klemp, K.F.2
-
90
-
-
0028053106
-
Formation of cholesterol monohydrate crystals in macrophagederived foam cells
-
Tangirala, R. K., W. G. Jerome, N. L. Jones, D. M. Small, W. J. Johnson, J. M. Glick, F. H. Mahlberg, and G. H. Rothblat. 1994. Formation of cholesterol monohydrate crystals in macrophagederived foam cells. J. Lipid Res. 35: 93-104.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 93-104
-
-
Tangirala, R.K.1
Jerome, W.G.2
Jones, N.L.3
Small, D.M.4
Johnson, W.J.5
Glick, J.M.6
Mahlberg, F.H.7
Rothblat, G.H.8
-
91
-
-
0031943893
-
Effects of intracellular free cholesterol accumulation on macrophage viability: A model for foam cell death
-
Kellner-Weibel, G., W. G. Jerome, D. M. Small, G. J. Warner, J. K. Stoltenborg, M. A. Kearney, M. H. Corjay, M. C. Phillips, and G. H. Rothblat. 1998. Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death. Arterioscler. Thromb. Vasc. Biol. 18: 423-431.
-
(1998)
Arterioscler. Thromb. Vasc. Biol.
, vol.18
, pp. 423-431
-
-
Kellner-Weibel, G.1
Jerome, W.G.2
Small, D.M.3
Warner, G.J.4
Stoltenborg, J.K.5
Kearney, M.A.6
Corjay, M.H.7
Phillips, M.C.8
Rothblat, G.H.9
-
92
-
-
0032800248
-
Crystallization of free cholesterol in model macrophage foam cells
-
Kellner-Weibel, G., P. G. Yancey, W. G. Jerome, T. Walser, R. P. Mason, M. C. Phillips, and G. H. Rothblat. 1999. Crystallization of free cholesterol in model macrophage foam cells. Arterioscler. Thromb. Vasc. Biol. 19: 1891-1898.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1891-1898
-
-
Kellner-Weibel, G.1
Yancey, P.G.2
Jerome, W.G.3
Walser, T.4
Mason, R.P.5
Phillips, M.C.6
Rothblat, G.H.7
-
93
-
-
84880777411
-
CD36 coordinates NLRP3 infl ammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile infl ammation
-
Sheedy, F. J., A. Grebe, K. J. Rayner, P. Kalantari, B. Ramkhelawon , S. B. Carpenter, C. E. Becker, H. N. Ediriweera, A. E. Mullick , D. T. Golenbock, et al. 2013. CD36 coordinates NLRP3 infl ammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile infl ammation. Nat. Immunol. 14: 812-820.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 812-820
-
-
Sheedy, F.J.1
Grebe, A.2
Rayner, K.J.3
Kalantari, P.4
Ramkhelawon, B.5
Carpenter, S.B.6
Becker, C.E.7
Ediriweera, H.N.8
Mullick, A.E.9
Golenbock, D.T.10
-
94
-
-
1042276704
-
Cholesterol crystal nucleation from enzymatically modifi ed low-density lipoproteins: Combined effect of sphingomyelinase and cholesterol esterase
-
Guarino, A. J., T. N. Tulenko, and S. P. Wrenn. 2004. Cholesterol crystal nucleation from enzymatically modifi ed low-density lipoproteins: combined effect of sphingomyelinase and cholesterol esterase. Biochemistry. 43: 1685-1693.
-
(2004)
Biochemistry
, vol.43
, pp. 1685-1693
-
-
Guarino, A.J.1
Tulenko, T.N.2
Wrenn, S.P.3
-
95
-
-
0017356614
-
Effect of an aqueous phase on the solubility of cholesterol in an oil phase
-
Jandacek, R. J., M. R. Webb, and F. H. Mattson. 1977. Effect of an aqueous phase on the solubility of cholesterol in an oil phase. J. Lipid Res. 18: 203-210.
-
(1977)
J. Lipid Res.
, vol.18
, pp. 203-210
-
-
Jandacek, R.J.1
Webb, M.R.2
Mattson, F.H.3
-
96
-
-
60649083763
-
Physical factors that trigger cholesterol crystallization leading to plaque rupture
-
Vedre, A., D. R. Pathak, M. Crimp, C. Lum, M. Koochesfahani , and G. S. Abela. 2009. Physical factors that trigger cholesterol crystallization leading to plaque rupture. Atherosclerosis. 203: 89-96.
-
(2009)
Atherosclerosis
, vol.203
, pp. 89-96
-
-
Vedre, A.1
Pathak, D.R.2
Crimp, M.3
Lum, C.4
Koochesfahani, M.5
Abela, G.S.6
-
97
-
-
34548850341
-
Uniform particles of pure and silica-coated cholesterol
-
Uskoković, V., and E. Matijevic. 2007. Uniform particles of pure and silica-coated cholesterol. J. Colloid Interface Sci. 315: 500-511.
-
(2007)
J. Colloid Interface Sci.
, vol.315
, pp. 500-511
-
-
Uskoković, V.1
Matijevic, E.2
-
98
-
-
73349093412
-
Lipoprotein modifi cation by secretory phospholipase A(2) enzymes contributes to the initiation and progression of atherosclerosis
-
Oörni, K., and P. T. Kovanen. 2009. Lipoprotein modifi cation by secretory phospholipase A(2) enzymes contributes to the initiation and progression of atherosclerosis. Curr. Opin. Lipidol. 20: 421-427.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 421-427
-
-
Oörni, K.1
Kovanen, P.T.2
-
99
-
-
84905163411
-
Toll-like receptor, lipotoxicity and chronic infl ammation: The pathological link between obesity and cardiometabolic disease
-
Eguchi, K., and I. Manabe. 2014. Toll-like receptor, lipotoxicity and chronic infl ammation: The pathological link between obesity and cardiometabolic disease. J. Atheroscler. Thromb. 21: 629-639.
-
(2014)
J. Atheroscler. Thromb.
, vol.21
, pp. 629-639
-
-
Eguchi, K.1
Manabe, I.2
-
100
-
-
8644239488
-
Increased lysophosphatidylcholine and non-esterifi ed fatty acid content in LDL induces chemokine release in endothelial cells. Relationship with electronegative LDL
-
Benítez, S., M. Camacho, R. Arcelus, L. Vila, C. Bancells, J. Ordonez-Llanos, and J. L. Sanchez-Quesada. 2004. Increased lysophosphatidylcholine and non-esterifi ed fatty acid content in LDL induces chemokine release in endothelial cells. Relationship with electronegative LDL. Atherosclerosis. 177: 299-305.
-
(2004)
Atherosclerosis
, vol.177
, pp. 299-305
-
-
Benítez, S.1
Camacho, M.2
Arcelus, R.3
Vila, L.4
Bancells, C.5
Ordonez-Llanos, J.6
Sanchez-Quesada, J.L.7
-
101
-
-
0032948306
-
Lysophosphatidylcholine (LPC) induces proinfl ammatory cytokines by a platelet-activating factor (PAF) receptor- dependent mechanism
-
Huang, Y. H., L. Schafer-Elinder, R. Wu, H. E. Claesson, and J. Frostegard. 1999. Lysophosphatidylcholine (LPC) induces proinfl ammatory cytokines by a platelet-activating factor (PAF) receptor- dependent mechanism. Clin. Exp. Immunol. 116: 326-331.
-
(1999)
Clin. Exp. Immunol.
, vol.116
, pp. 326-331
-
-
Huang, Y.H.1
Schafer-Elinder, L.2
Wu, R.3
Claesson, H.E.4
Frostegard, J.5
-
102
-
-
58549105701
-
Induction of proinfl ammatory cytokines by long-chain saturated fatty acids in human macrophages
-
Haversen, L., K. N. Danielsson, L. Fogelstrand, and O. Wiklund. 2009. Induction of proinfl ammatory cytokines by long-chain saturated fatty acids in human macrophages. Atherosclerosis. 202: 382-393.
-
(2009)
Atherosclerosis
, vol.202
, pp. 382-393
-
-
Haversen, L.1
Danielsson, K.N.2
Fogelstrand, L.3
Wiklund, O.4
-
104
-
-
49949092132
-
Role of secretory phospholipases in atherogenesis
-
Jönsson-Rylander, A. C., S. Lundin, B. Rosengren, C. Pettersson , and E. Hurt-Camejo. 2008. Role of secretory phospholipases in atherogenesis. Curr. Atheroscler. Rep. 10: 252-259.
-
(2008)
Curr. Atheroscler. Rep.
, vol.10
, pp. 252-259
-
-
Jönsson-Rylander, A.C.1
Lundin, S.2
Rosengren, B.3
Pettersson, C.4
Hurt-Camejo, E.5
-
105
-
-
33745959294
-
Secretory phospholipase A2 group V: Lesion distribution, activation by arterial proteoglycans, and induction in aorta by a Western diet
-
Rosengren, B., H. Peilot, M. Umaerus, A. C. Jonsson-Rylander, L. Mattsson-Hulten, C. Hallberg, P. Cronet, M. Rodriguez-Lee, and E. Hurt-Camejo. 2006. Secretory phospholipase A2 group V: lesion distribution, activation by arterial proteoglycans, and induction in aorta by a Western diet. Arterioscler. Thromb. Vasc. Biol. 26: 1579-1585.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 1579-1585
-
-
Rosengren, B.1
Peilot, H.2
Umaerus, M.3
Jonsson-Rylander, A.C.4
Mattsson-Hulten, L.5
Hallberg, C.6
Cronet, P.7
Rodriguez-Lee, M.8
Hurt-Camejo, E.9
-
106
-
-
33847048222
-
Group v secretory phospholipase A2 promotes atherosclerosis: Evidence from genetically altered mice
-
Bostrom, M. A., B. B. Boyanovsky, C. T. Jordan, M. P. Wadsworth, D. J. Taatjes, F. C. de Beer, and N. R. Webb. 2007. Group v secretory phospholipase A2 promotes atherosclerosis: evidence from genetically altered mice. Arterioscler. Thromb. Vasc. Biol. 27: 600-606.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 600-606
-
-
Bostrom, M.A.1
Boyanovsky, B.B.2
Jordan, C.T.3
Wadsworth, M.P.4
Taatjes, D.J.5
De Beer, F.C.6
Webb, N.R.7
-
107
-
-
49449090767
-
Biochemistry and physiology of mammalian secreted phospholipases A2
-
Lambeau, G., and M. H. Gelb. 2008. Biochemistry and physiology of mammalian secreted phospholipases A2. Annu. Rev. Biochem. 77: 495-520.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 495-520
-
-
Lambeau, G.1
Gelb, M.H.2
-
108
-
-
33750933123
-
The interfacial binding surface of phospholipase A 2 s
-
Winget, J. M., Y. H. Pan, and B. J. Bahnson. 2006. The interfacial binding surface of phospholipase A 2 s. Biochim. Biophys. Acta. 1761: 1260-1269.
-
(2006)
Biochim. Biophys. Acta.
, vol.1761
, pp. 1260-1269
-
-
Winget, J.M.1
Pan, Y.H.2
Bahnson, B.J.3
-
109
-
-
34047237965
-
Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: Relation between interfacial electrostatics, intramembrane potential, and bending elasticity
-
Zhou, Y., and R. M. Raphael. 2007. Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending elasticity. Biophys. J. 92: 2451-2462.
-
(2007)
Biophys. J.
, vol.92
, pp. 2451-2462
-
-
Zhou, Y.1
Raphael, R.M.2
-
110
-
-
77649271967
-
Membrane simulations mimicking acidic pH reveal increased thickness and negative curvature in a bilayer consisting of lysophosphatidylcholines and free fatty acids
-
Lähdesmäki, K., O. H. Ollila, A. Koivuniemi, P. T. Kovanen, and M. T. Hyvönen. 2010. Membrane simulations mimicking acidic pH reveal increased thickness and negative curvature in a bilayer consisting of lysophosphatidylcholines and free fatty acids. Biochim. Biophys. Acta. 1798: 938-946.
-
(2010)
Biochim. Biophys. Acta.
, vol.1798
, pp. 938-946
-
-
Lähdesmäki, K.1
Ollila, O.H.2
Koivuniemi, A.3
Kovanen, P.T.4
Hyvönen, M.T.5
-
111
-
-
70450241001
-
Phospholipase A(2)- modifi ed LDL particles retain the generated hydrolytic products and are more atherogenic at acidic pH
-
Lähdesmäki, K., R. Plihtari, P. Soininen, E. Hurt-Camejo, M. Ala- Korpela, K. Öörni, and P. T. Kovanen. 2009. Phospholipase A(2)- modifi ed LDL particles retain the generated hydrolytic products and are more atherogenic at acidic pH. Atherosclerosis. 207: 352-359.
-
(2009)
Atherosclerosis
, vol.207
, pp. 352-359
-
-
Lähdesmäki, K.1
Plihtari, R.2
Soininen, P.3
Hurt-Camejo, E.4
Ala- Korpela, M.5
Öörni, K.6
Kovanen, P.T.7
-
112
-
-
0016691920
-
Fatty acid binding to plasma albumin
-
Spector, A. A. 1975. Fatty acid binding to plasma albumin. J. Lipid Res. 16: 165-179.
-
(1975)
J. Lipid Res.
, vol.16
, pp. 165-179
-
-
Spector, A.A.1
-
113
-
-
0036693935
-
How fatty acids bind to proteins: The inside story from protein structures
-
Hamilton, J. A. 2002. How fatty acids bind to proteins: the inside story from protein structures. Prostaglandins Leukot. Essent. Fatty Acids. 67: 65-72.
-
(2002)
Prostaglandins Leukot. Essent. Fatty Acids.
, vol.67
, pp. 65-72
-
-
Hamilton, J.A.1
-
114
-
-
0032579258
-
Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development
-
Schissel, S. L., X. Jiang, J. Tweedie-Hardman, T. Jeong, E. H. Camejo, J. Najib, J. H. Rapp, K. J. Williams, and I. Tabas. 1998. Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development. J. Biol. Chem. 273: 2738-2746.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2738-2746
-
-
Schissel, S.L.1
Jiang, X.2
Tweedie-Hardman, J.3
Jeong, T.4
Camejo, E.H.5
Najib, J.6
Rapp, J.H.7
Williams, K.J.8
Tabas, I.9
-
115
-
-
0029666484
-
Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene
-
Schissel, S. L., E. H. Schuchman, K. J. Williams, and I. Tabas. 1996. Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene. J. Biol. Chem. 271: 18431-18436.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18431-18436
-
-
Schissel, S.L.1
Schuchman, E.H.2
Williams, K.J.3
Tabas, I.4
-
116
-
-
84864859102
-
Conformational changes of apoB-100 in SMase-modifi ed LDL mediate formation of large aggregates at acidic pH
-
Sneck, M., S. D. Nguyen, T. Pihlajamaa, G. Yohannes, M. L. Riekkola, R. Milne, P. T. Kovanen, and K. Öörni. 2012. Conformational changes of apoB-100 in SMase-modifi ed LDL mediate formation of large aggregates at acidic pH. J. Lipid Res. 53: 1832-1839.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 1832-1839
-
-
Sneck, M.1
Nguyen, S.D.2
Pihlajamaa, T.3
Yohannes, G.4
Riekkola, M.L.5
Milne, R.6
Kovanen, P.T.7
Öörni, K.8
-
117
-
-
0029762320
-
Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins
-
Schissel, S. L., J. Tweedie-Hardman, J. H. Rapp, G. Graham, K. J. Williams, and I. Tabas. 1996. Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins. J. Clin. Invest. 98: 1455-1464.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1455-1464
-
-
Schissel, S.L.1
Tweedie-Hardman, J.2
Rapp, J.H.3
Graham, G.4
Williams, K.J.5
Tabas, I.6
-
118
-
-
33750052551
-
Ceramide drives cholesterol out of the ordered lipid bilayer phase into the crystal phase in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/cholesterol/ceramide ternary mixtures
-
Ali, M. R., K. H. Cheng, and J. Huang. 2006. Ceramide drives cholesterol out of the ordered lipid bilayer phase into the crystal phase in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/cholesterol/ceramide ternary mixtures. Biochemistry. 45: 12629-12638.
-
(2006)
Biochemistry
, vol.45
, pp. 12629-12638
-
-
Ali, M.R.1
Cheng, K.H.2
Huang, J.3
-
119
-
-
33845349236
-
Sphingolipids and the formation of sterol-enriched ordered membrane domains
-
Ramstedt, B., and J. P. Slotte. 2006. Sphingolipids and the formation of sterol-enriched ordered membrane domains. Biochim. Biophys. Acta. 1758: 1945-1956.
-
(2006)
Biochim. Biophys. Acta.
, vol.1758
, pp. 1945-1956
-
-
Ramstedt, B.1
Slotte, J.P.2
-
120
-
-
84860774384
-
Oxidation of low-density lipoprotein by iron at lysosomal pH: Implications for atherosclerosis
-
Satchell, L., and D. S. Leake. 2012. Oxidation of low-density lipoprotein by iron at lysosomal pH: implications for atherosclerosis. Biochemistry. 51: 3767-3775.
-
(2012)
Biochemistry
, vol.51
, pp. 3767-3775
-
-
Satchell, L.1
Leake, D.S.2
-
121
-
-
33745482661
-
LDL oxidized with iron in the presence of homocysteine/cystine at acidic pH has low cytotoxicity despite high lipid peroxidation
-
Pfanzagl, B. 2006. LDL oxidized with iron in the presence of homocysteine/cystine at acidic pH has low cytotoxicity despite high lipid peroxidation. Atherosclerosis. 187: 292-300.
-
(2006)
Atherosclerosis
, vol.187
, pp. 292-300
-
-
Pfanzagl, B.1
-
122
-
-
0038852300
-
Oxidation of low density lipoprotein particles decreases their ability to bind to human aortic proteoglycans. Dependence on oxidative modifi cation of the lysine residues
-
Oörni, K., M. O. Pentikäinen, A. Annila, and P. T. Kovanen. 1997. Oxidation of low density lipoprotein particles decreases their ability to bind to human aortic proteoglycans. Dependence on oxidative modifi cation of the lysine residues. J. Biol. Chem. 272: 21303-21311.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21303-21311
-
-
Oörni, K.1
Pentikäinen, M.O.2
Annila, A.3
Kovanen, P.T.4
-
124
-
-
23644458916
-
You are right too!
-
Witztum, J. L. 2005. You are right too! J. Clin. Invest. 115 : 2072-2075.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2072-2075
-
-
Witztum, J.L.1
-
125
-
-
79960696690
-
Acidity increases the uptake of native LDL by human monocyte-derived macrophages
-
Plihtari, R., P. T. Kovanen, and K. Öörni. 2011. Acidity increases the uptake of native LDL by human monocyte-derived macrophages. Atherosclerosis. 217: 401-406.
-
(2011)
Atherosclerosis
, vol.217
, pp. 401-406
-
-
Plihtari, R.1
Kovanen, P.T.2
Öörni, K.3
-
126
-
-
0030803636
-
The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro
-
Fuki, I. V., K. M. Kuhn, I. R. Lomazov, V. L. Rothman, G. P. Tuszynski, R. V. Iozzo, T. L. Swenson, E. A. Fisher, and K. J. Williams. 1997. The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro. J. Clin. Invest. 100: 1611-1622.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1611-1622
-
-
Fuki, I.V.1
Kuhn, K.M.2
Lomazov, I.R.3
Rothman, V.L.4
Tuszynski, G.P.5
Iozzo, R.V.6
Swenson, T.L.7
Fisher, E.A.8
Williams, K.J.9
-
127
-
-
67449168509
-
Syndecan-4 mediates macrophage uptake of group v secretory phospholipase A2-modifi ed LDL
-
Boyanovsky, B. B., P. Shridas, M. Simons, D. R. van der Westhuyzen , and N. R. Webb. 2009. Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modifi ed LDL. J. Lipid Res. 50: 641-650.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 641-650
-
-
Boyanovsky, B.B.1
Shridas, P.2
Simons, M.3
Westhuyzen Der Van, D.R.4
Webb, N.R.5
-
128
-
-
0025118730
-
Transport, interactions and retention of plasma proteins in the intima: The barrier function of the internal elastic lamina
-
Smith, E. B. 1990. Transport, interactions and retention of plasma proteins in the intima: the barrier function of the internal elastic lamina. Eur. Heart J. 11(Suppl E): 72-81.
-
(1990)
Eur. Heart J.
, vol.11
, pp. 72-81
-
-
Smith, E.B.1
-
129
-
-
33744899360
-
Constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-colonystimulating factor (M-CSF)
-
Zhao, B., Y. Li, C. Buono, S. W. Waldo, N. L. Jones, M. Mori, and H. S. Kruth. 2006. Constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-colonystimulating factor (M-CSF). J. Biol. Chem. 281: 15757-15762.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15757-15762
-
-
Zhao, B.1
Li, Y.2
Buono, C.3
Waldo, S.W.4
Jones, N.L.5
Mori, M.6
Kruth, H.S.7
-
130
-
-
79953192995
-
HDL and cardiovascular disease: Atherogenic and atheroprotective mechanisms
-
Navab, M., S. T. Reddy, B. J. Van Lenten, and A. M. Fogelman. 2011. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat. Rev. Cardiol. 8: 222-232.
-
(2011)
Nat. Rev. Cardiol.
, vol.8
, pp. 222-232
-
-
Navab, M.1
Reddy, S.T.2
Van Lenten, B.J.3
Fogelman, A.M.4
-
131
-
-
84880441299
-
HDL cholesterol and cardiovascular outcomes: What is the evidence?
-
Rubenfi re, M., and R. D. Brook. 2013. HDL cholesterol and cardiovascular outcomes: what is the evidence? Curr. Cardiol. Rep. 15: 349.
-
(2013)
Curr. Cardiol. Rep.
, vol.15
, pp. 349
-
-
Rubenfire, M.1
Brook, R.D.2
-
132
-
-
84892938632
-
High-density lipoprotein and atherosclerosis regression: Evidence from preclinical and clinical studies
-
Feig, J. E., B. Hewing, J. D. Smith, S. L. Hazen, and E. A. Fisher. 2014. High-density lipoprotein and atherosclerosis regression: evidence from preclinical and clinical studies. Circ. Res. 114: 205-213.
-
(2014)
Circ. Res.
, vol.114
, pp. 205-213
-
-
Feig, J.E.1
Hewing, B.2
Smith, J.D.3
Hazen, S.L.4
Fisher, E.A.5
-
134
-
-
84877655587
-
The role of the gut in reverse cholesterol transport-focus on the enterocyte
-
Lee-Rueckert, M., F. Blanco-Vaca, P. T. Kovanen, and J. C. Escola- Gil. 2013. The role of the gut in reverse cholesterol transport-focus on the enterocyte. Prog. Lipid Res. 52: 317-328.
-
(2013)
Prog. Lipid Res.
, vol.52
, pp. 317-328
-
-
Lee-Rueckert, M.1
Blanco-Vaca, F.2
Kovanen, P.T.3
Escola-Gil, J.C.4
-
135
-
-
33745132444
-
Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
-
Cuchel, M., and D. J. Rader. 2006. Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation. 113: 2548-2555.
-
(2006)
Circulation.
, vol.113
, pp. 2548-2555
-
-
Cuchel, M.1
Rader, D.J.2
-
136
-
-
73949099847
-
Stimulation of cholesterol effl ux by LXR agonists in cholesterolloaded human macrophages is ABCA1-dependent but ABCG1- independent
-
Larrede, S., C. M. Quinn, W. Jessup, E. Frisdal, M. Olivier, V. Hsieh, M. J. Kim, M. Van Eck, P. Couvert, A. Carrie, et al. 2009. Stimulation of cholesterol effl ux by LXR agonists in cholesterolloaded human macrophages is ABCA1-dependent but ABCG1- independent. Arterioscler. Thromb. Vasc. Biol. 29: 1930-1936.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 1930-1936
-
-
Larrede, S.1
Quinn, C.M.2
Jessup, W.3
Frisdal, E.4
Olivier, M.5
Hsieh, V.6
Kim, M.J.7
Van Eck, M.8
Couvert, P.9
Carrie, A.10
-
137
-
-
79957882578
-
Metabolic and functional relevance of HDL subspecies
-
Asztalos, B. F., M. Tani, and E. J. Schaefer. 2011. Metabolic and functional relevance of HDL subspecies. Curr. Opin. Lipidol. 22 : 176-185.
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 176-185
-
-
Asztalos, B.F.1
Tani, M.2
Schaefer, E.J.3
-
138
-
-
0033515841
-
Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): Evidence for sterol-dependent regulation in macrophages
-
Langmann, T., J. Klucken, M. Reil, G. Liebisch, M. F. Luciani, G. Chimini, W. E. Kaminski, and G. Schmitz. 1999. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. Biochem. Biophys. Res. Commun. 257: 29-33.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 29-33
-
-
Langmann, T.1
Klucken, J.2
Reil, M.3
Liebisch, G.4
Luciani, M.F.5
Chimini, G.6
Kaminski, W.E.7
Schmitz, G.8
-
139
-
-
84875237109
-
Hypoxia in murine atherosclerotic plaques and its adverse effects on macrophages
-
Parathath, S., Y. Yang, S. Mick, and E. A. Fisher. 2013. Hypoxia in murine atherosclerotic plaques and its adverse effects on macrophages. Trends Cardiovasc. Med. 23: 80-84.
-
(2013)
Trends Cardiovasc. Med.
, vol.23
, pp. 80-84
-
-
Parathath, S.1
Yang, Y.2
Mick, S.3
Fisher, E.A.4
-
140
-
-
84871808159
-
Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin
-
Maitra, U., and L. Li. 2013. Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin. Arterioscler. Thromb. Vasc. Biol. 33 : 24-33.
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 24-33
-
-
Maitra, U.1
Li, L.2
-
141
-
-
33751069000
-
Oxidative stress infl uences cholesterol effl ux in THP-1 macrophages: Role of ATP-binding cassette A1 and nuclear factors
-
Marcil, V., E. Delvin, A. T. Sane, A. Tremblay, and E. Levy. 2006. Oxidative stress infl uences cholesterol effl ux in THP-1 macrophages: role of ATP-binding cassette A1 and nuclear factors. Cardiovasc. Res. 72: 473-482.
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 473-482
-
-
Marcil, V.1
Delvin, E.2
Sane, A.T.3
Tremblay, A.4
Levy, E.5
-
142
-
-
77955982655
-
Acidic extracellular environments strongly impair ABCA1-mediated cholesterol effl ux from human macrophage foam cells
-
Lee-Rueckert, M., J. Lappalainen, H. Leinonen, T. Pihlajamaa, M. Jauhiainen, and P. T. Kovanen. 2010. Acidic extracellular environments strongly impair ABCA1-mediated cholesterol effl ux from human macrophage foam cells. Arterioscler. Thromb. Vasc. Biol. 30 : 1766-1772.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1766-1772
-
-
Lee-Rueckert, M.1
Lappalainen, J.2
Leinonen, H.3
Pihlajamaa, T.4
Jauhiainen, M.5
Kovanen, P.T.6
-
143
-
-
9444269227
-
ABCA1 expression in carotid atherosclerotic plaques
-
Albrecht, C., S. Soumian, J. S. Amey, A. Sardini, C. F. Higgins, A. H. Davies, and R. G. Gibbs. 2004. ABCA1 expression in carotid atherosclerotic plaques. Stroke. 35: 2801-2806.
-
(2004)
Stroke
, vol.35
, pp. 2801-2806
-
-
Albrecht, C.1
Soumian, S.2
Amey, J.S.3
Sardini, A.4
Higgins, C.F.5
Davies, A.H.6
Gibbs, R.G.7
-
144
-
-
23244446833
-
Genes of cholesterol metabolism in human atheroma: Overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression
-
Forcheron, F., L. Legedz, G. Chinetti, P. Feugier, D. Letexier , G. Bricca, and M. Beylot. 2005. Genes of cholesterol metabolism in human atheroma: overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression. Arterioscler. Thromb. Vasc. Biol. 25: 1711-1717.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 1711-1717
-
-
Forcheron, F.1
Legedz, L.2
Chinetti, G.3
Feugier, P.4
Letexier, D.5
Bricca, G.6
Beylot, M.7
-
145
-
-
0035095882
-
Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues
-
Lawn, R. M., D. P. Wade, T. L. Couse, and J. N. Wilcox. 2001. Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues. Arterioscler. Thromb. Vasc. Biol. 21: 378-385.
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 378-385
-
-
Lawn, R.M.1
Wade, D.P.2
Couse, T.L.3
Wilcox, J.N.4
-
146
-
-
47049089673
-
ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytic compartments
-
Denis, M., Y. D. Landry, and X. Zha. 2008. ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytic compartments. J. Biol. Chem. 283: 16178-16186.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16178-16186
-
-
Denis, M.1
Landry, Y.D.2
Zha, X.3
-
147
-
-
84857629676
-
Lysine residues of ABCA1 are required for the interaction with apoA-I
-
Nagao, K., Y. Kimura, and K. Ueda. 2012. Lysine residues of ABCA1 are required for the interaction with apoA-I. Biochim. Biophys. Acta. 1821: 530-535.
-
(2012)
Biochim. Biophys. Acta.
, vol.1821
, pp. 530-535
-
-
Nagao, K.1
Kimura, Y.2
Ueda, K.3
-
148
-
-
33947205478
-
The C-terminal lipid-binding domain of apolipoprotein e is a highly effi cient mediator of ABCA1-dependent cholesterol effl ux that promotes the assembly of high-density lipoproteins
-
Vedhachalam, C., V. Narayanaswami, N. Neto, T. M. Forte, M. C. Phillips, S. Lund-Katz, and J. K. Bielicki. 2007. The C-terminal lipid-binding domain of apolipoprotein E is a highly effi cient mediator of ABCA1-dependent cholesterol effl ux that promotes the assembly of high-density lipoproteins. Biochemistry. 46: 2583-2593.
-
(2007)
Biochemistry
, vol.46
, pp. 2583-2593
-
-
Vedhachalam, C.1
Narayanaswami, V.2
Neto, N.3
Forte, T.M.4
Phillips, M.C.5
Lund-Katz, S.6
Bielicki, J.K.7
-
149
-
-
75149124430
-
Role of HDL, ABCA1, and ABCG1 transporters in cholesterol effl ux and immune responses
-
Yvan-Charvet, L., N. Wang, and A. R. Tall. 2010. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol effl ux and immune responses. Arterioscler. Thromb. Vasc. Biol. 30: 139-143.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 139-143
-
-
Yvan-Charvet, L.1
Wang, N.2
Tall, A.R.3
-
150
-
-
0029005884
-
Cycling of apolipoprotein A-I between lipid-associated and lipid-free pools
-
Liang, H. Q., K. A. Rye, and P. J. Barter. 1995. Cycling of apolipoprotein A-I between lipid-associated and lipid-free pools. Biochim. Biophys. Acta. 1257: 31-37.
-
(1995)
Biochim. Biophys. Acta.
, vol.1257
, pp. 31-37
-
-
Liang, H.Q.1
Rye, K.A.2
Barter, P.J.3
-
151
-
-
77950615091
-
Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles
-
Lund-Katz, S., D. Nguyen, P. Dhanasekaran, M. Kono, M. Nickel , H. Saito, and M. C. Phillips. 2010. Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles. J. Lipid Res. 51: 606-617.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 606-617
-
-
Lund-Katz, S.1
Nguyen, D.2
Dhanasekaran, P.3
Kono, M.4
Nickel, M.5
Saito, H.6
Phillips, M.C.7
-
152
-
-
84866154354
-
Spontaneous remodeling of HDL particles at acidic pH enhances their capacity to induce cholesterol effl ux from human macrophage foam cells
-
Nguyen, S. D., K. Öörni, M. Lee-Rueckert, T. Pihlajamaa, J. Metso , M. Jauhiainen, and P. T. Kovanen. 2012. Spontaneous remodeling of HDL particles at acidic pH enhances their capacity to induce cholesterol effl ux from human macrophage foam cells. J. Lipid Res. 53: 2115-2125.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2115-2125
-
-
Nguyen, S.D.1
Öörni, K.2
Lee-Rueckert, M.3
Pihlajamaa, T.4
Metso, J.5
Jauhiainen, M.6
Kovanen, P.T.7
-
153
-
-
80052774240
-
Extracellular modifi - Cations of HDL in vivo and the emerging concept of proteolytic inactivation of prebeta-HDL
-
Lee-Rueckert, M., and P. T. Kovanen. 2011. Extracellular modifi - cations of HDL in vivo and the emerging concept of proteolytic inactivation of prebeta-HDL. Curr. Opin. Lipidol. 22: 394-402.
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, pp. 394-402
-
-
Lee-Rueckert, M.1
Kovanen, P.T.2
-
155
-
-
0344926410
-
Cathepsins F and S block HDL3-induced cholesterol effl ux from macrophage foam cells
-
Lindstedt, L., M. Lee, K. Öörni, D. Brömme, and P. T. Kovanen. 2003. Cathepsins F and S block HDL3-induced cholesterol effl ux from macrophage foam cells. Biochem. Biophys. Res. Commun. 312 : 1019-1024.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 1019-1024
-
-
Lindstedt, L.1
Lee, M.2
Öörni, K.3
Brömme, D.4
Kovanen, P.T.5
-
156
-
-
84883800208
-
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
-
Robbins, C. S., I. Hilgendorf, G. F. Weber, I. Theurl, Y. Iwamoto , J. L. Figueiredo, R. Gorbatov, G. K. Sukhova, L. M. Gerhardt, D. Smyth, et al. 2013. Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat. Med. 19: 1166-1172.
-
(2013)
Nat. Med.
, vol.19
, pp. 1166-1172
-
-
Robbins, C.S.1
Hilgendorf, I.2
Weber, G.F.3
Theurl, I.4
Iwamoto, Y.5
Figueiredo, J.L.6
Gorbatov, R.7
Sukhova, G.K.8
Gerhardt, L.M.9
Smyth, D.10
-
157
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R. A., and R. J. Gillies. 2004. Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer. 4: 891-899.
-
(2004)
Nat. Rev. Cancer.
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
158
-
-
79151482415
-
Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis
-
Brenninkmeijer, L., C. Kuehl, A. M. Geldart, E. Arons, and H. Christou. 2011. Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis. J. Vasc. Res. 48 : 285-296.
-
(2011)
J. Vasc. Res.
, vol.48
, pp. 285-296
-
-
Brenninkmeijer, L.1
Kuehl, C.2
Geldart, A.M.3
Arons, E.4
Christou, H.5
-
159
-
-
0028085059
-
Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an infl ammatory process irrespective of the dominant plaque morphology
-
van der Wal, A. C., A. E. Becker, C. M. van der Loos, and P. K. Das. 1994. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an infl ammatory process irrespective of the dominant plaque morphology. Circulation. 89: 36-44.
-
(1994)
Circulation.
, vol.89
, pp. 36-44
-
-
Van Der Wal, A.C.1
Becker, A.E.2
Loos Der Van, C.M.3
Das, P.K.4
-
160
-
-
84901999902
-
Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy
-
Du, J. Z., C. Q. Mao, Y. Y. Yuan, X. Z. Yang, and J. Wang. 2014. Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy. Biotechnol. Adv. 32: 789-803.
-
(2014)
Biotechnol. Adv.
, vol.32
, pp. 789-803
-
-
Du, J.Z.1
Mao, C.Q.2
Yuan, Y.Y.3
Yang, X.Z.4
Wang, J.5
-
161
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom, R. L., D. E. Bauer, M. Buzzai, R. Karnauskas, M. H. Harris, D. R. Plas, H. Zhuang, R. M. Cinalli, A. Alavi, C. M. Rudin , et al. 2004. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 64: 3892-3899.
-
(2004)
Cancer Res.
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
|