Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein: Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins

Journal of Clinical Investigation

Volumn 98, Issue 6, 1996, Pages 1455-1464

  Schissel, Scott L ^a   Tweedie Hardman, Judith ^c   Rapp, Joseph H ^e   Graham, George ^b,c   Williams, Kevin Jon ^d   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b University of California ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

atherosclerosis; ceramide; foam cells; hydrolytic enzymes; phospholipids

Indexed keywords

LOW DENSITY LIPOPROTEIN; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROGENESIS; FOAM CELL; HUMAN; HUMAN TISSUE; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; RABBIT;

EID: 0029762320     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118934     Document Type: Article

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