Phospholipase A2-modified LDL particles retain the generated hydrolytic products and are more atherogenic at acidic pH

Atherosclerosis

Volumn 207, Issue 2, 2009, Pages 352-359

  Lähdesmäki, Katariina ^a   Plihtari, Riia ^a   Soininen, Pasi ^b   Hurt Camejo, Eva ^c   Ala Korpela, Mika ^d   Öörni, Katariina ^a   Kovanen, Petri T ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c ASTRAZENECA R AND D   (Sweden)

^d UNIVERSITY OF OULU   (Finland)

Author keywords

LDL; Macrophage; NMR; Phospholipase A2; Proteoglycans

Indexed keywords

ALBUMIN; FATTY ACID; LOW DENSITY LIPOPROTEIN; LYSOPHOSPHOLIPID; PHOSPHOLIPASE A2; PROTEOGLYCAN;

ACIDITY; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; BINDING AFFINITY; CONTROLLED STUDY; FOAM CELL; HUMAN; HUMAN CELL; HYDROLYSIS; LIPOLYSIS; MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION;

AORTA; ATHEROSCLEROSIS; CELLS, CULTURED; FATTY ACIDS, NONESTERIFIED; FOAM CELLS; GROUP V PHOSPHOLIPASES A2; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOLYSIS; LIPOPROTEINS, LDL; LYSOPHOSPHOLIPIDS; PROTEIN BINDING; PROTEOGLYCANS; RECOMBINANT PROTEINS; SERUM ALBUMIN; TIME FACTORS;

EID: 70450241001     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.04.031     Document Type: Article

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