메뉴 건너뛰기




Volumn 20, Issue 10, 2013, Pages 743-754

Pathogenic role of modified LDL antibodies and immune complexes in atherosclerosis

Author keywords

Atherosclerosis; Autoimmunity; Immune complexes; Modified LDL; Modified LDL antibodies

Indexed keywords

FC RECEPTOR; HEXANOYL LYSINE LOW DENSITY LIPOPROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M ANTIBODY; METHYLGLYOXAL LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; UNCLASSIFIED DRUG;

EID: 84886645705     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.19281     Document Type: Review
Times cited : (43)

References (105)
  • 1
    • 84865485915 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P: Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol, 2012; 32: 2045-2051.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2045-2051
    • Libby, P.1
  • 2
    • 80155214095 scopus 로고    scopus 로고
    • Cellular immunity, lowdensity lipoprotein and atherosclerosis: Break of tolerance in the artery wall
    • Ketelhuth DF, Hansson GK: Cellular immunity, lowdensity lipoprotein and atherosclerosis: Break of tolerance in the artery wall. Thromb Haemost, 2011; 106: 779-786.
    • (2011) Thromb Haemost , vol.106 , pp. 779-786
    • Ketelhuth, D.F.1    Hansson, G.K.2
  • 3
    • 71949107774 scopus 로고    scopus 로고
    • Innate immune signals in atherosclerosis
    • Lundberg AM, Hansson GK: Innate immune signals in atherosclerosis. Clin Immunol, 2010; 134: 5-24.
    • (2010) Clin Immunol , vol.134 , pp. 5-24
    • Lundberg, A.M.1    Hansson, G.K.2
  • 5
    • 71949091994 scopus 로고    scopus 로고
    • Clinical significance of the humoral immune response to modified LDL
    • Lopes-Virella MF, Virella G: Clinical significance of the humoral immune response to modified LDL. Clin Immunol, 2010; 134: 55-65.
    • (2010) Clin Immunol , vol.134 , pp. 55-65
    • Lopes-Virella, M.F.1    Virella, G.2
  • 6
    • 0028022781 scopus 로고
    • Oxidized lipoproteins, altered cell function and atherosclerosis
    • Penn MS, Chisolm GM: Oxidized lipoproteins, altered cell function and atherosclerosis. Atherosclerosis, 1994; 108: S21-29.
    • (1994) Atherosclerosis , vol.108
    • Penn, M.S.1    Chisolm, G.M.2
  • 7
    • 0020519662 scopus 로고
    • Enhanced macrophage degradation of biologically modified low density lipoprotein
    • Henriksen T, Mahoney ME, Steinberg D: Enhanced macrophage degradation of biologically modified low density lipoprotein. Arteriosclerosis, 1983; 3: 149-158.
    • (1983) Arteriosclerosis , vol.3 , pp. 149-158
    • Henriksen, T.1    Mahoney, M.E.2    Steinberg, D.3
  • 8
    • 0024605184 scopus 로고
    • Multiple receptors for modified LDL in mouse peritoneal macrophages: Different uptake mechanisms for acetylated and oxidized LDL
    • Arai K, Kita T, Yokode M, Narumiya S, Kawai C: Multiple receptors for modified LDL in mouse peritoneal macrophages: Different uptake mechanisms for acetylated and oxidized LDL. Biochem Biophys Res Commun, 1989; 159: 1375-1379.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 1375-1379
    • Arai, K.1    Kita, T.2    Yokode, M.3    Narumiya, S.4    Kawai, C.5
  • 10
    • 0024596121 scopus 로고
    • A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein
    • Sparrow CP, Parthasarathy S, Steinberg D: A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. J Biol Chem, 1989; 264: 2599-2604.
    • (1989) J Biol Chem , vol.264 , pp. 2599-2604
    • Sparrow, C.P.1    Parthasarathy, S.2    Steinberg, D.3
  • 11
    • 78049420726 scopus 로고    scopus 로고
    • Cd36 participates in a signaling pathway that regulates ROS formation in murine VSMCs
    • Li W, Febbraio M, Reddy SP, Yu DY, Yamamoto M, Silverstein RL: Cd36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. J Clin Invest, 2010; 120: 3996-4006.
    • (2010) J Clin Invest , vol.120 , pp. 3996-4006
    • Li, W.1    Febbraio, M.2    Reddy, S.P.3    Yu, D.Y.4    Yamamoto, M.5    Silverstein, R.L.6
  • 12
    • 0023192020 scopus 로고
    • Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/macrophages during atherogenesis
    • Quinn MT, Parthasarathy S, Fong LG, Steinberg D: Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Nat Acad Sci USA, 1987; 84: 2995-299.
    • (1987) Proc Nat Acad Sci USA , vol.84 , pp. 2995-2999
    • Quinn, M.T.1    Parthasarathy, S.2    Fong, L.G.3    Steinberg, D.4
  • 13
    • 0022399823 scopus 로고
    • Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of lowdensity lipoprotein
    • 82: 5949-5953, 1985
    • Quinn MT, Parthasarathy S, Steinberg D: Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of lowdensity lipoprotein. 82: 5949-5953, 1985. Proc Natl Acad Sci USA, 1985; 82: 5949-5953.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5949-5953
    • Quinn, M.T.1    Parthasarathy, S.2    Steinberg, D.3
  • 15
    • 0026781978 scopus 로고
    • Lysophosphatidyl- choline, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells
    • Kume N, Cybulsky MI, Gimbrone MAJ: Lysophosphatidyl- choline, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest, 1992; 90: 1138-1144.
    • (1992) J Clin Invest , vol.90 , pp. 1138-1144
    • Kume, N.1    Cybulsky, M.I.2    Gimbrone, M.A.J.3
  • 16
    • 0028945307 scopus 로고
    • Modified LDL and its constituents augment cytokine- activated vascular cell adhesion molecule -1 gene expression in human vascular endothelial cells
    • Kahn BV, Parthasarathy SS, Alexander RW, Medford RM: Modified LDL and its constituents augment cytokine- activated vascular cell adhesion molecule -1 gene expression in human vascular endothelial cells. J Clin Invest, 1995; 95: 1262-1270.
    • (1995) J Clin Invest , vol.95 , pp. 1262-1270
    • Kahn, B.V.1    Parthasarathy, S.S.2    Alexander, R.W.3    Medford, R.M.4
  • 17
    • 0035200471 scopus 로고    scopus 로고
    • Expression of adhesion molecules by human endothelial cells exposed to oxidized low density lipoprotein. Influences of degree of oxidation and location of oxidized LDL
    • Takei A, Huang Y, Lopes-Virella MF: Expression of adhesion molecules by human endothelial cells exposed to oxidized low density lipoprotein. Influences of degree of oxidation and location of oxidized LDL. Atherosclerosis, 2001; 154: 79-86.
    • (2001) Atherosclerosis , vol.154 , pp. 79-86
    • Takei, A.1    Huang, Y.2    Lopes-Virella, M.F.3
  • 20
    • 0000352972 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: Insights into the pathogenesis of macrovascular complications in diabetes
    • Wendt T, Bucciarelli L, Qu W, Lu Y, Yan SF, Stern DM, Schmidt AM: Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: Insights into the pathogenesis of macrovascular complications in diabetes. Curr Atheroscler Rep, 2002; 4: 228-237.
    • (2002) Curr Atheroscler Rep , vol.4 , pp. 228-237
    • Wendt, T.1    Bucciarelli, L.2    Qu, W.3    Lu, Y.4    Yan, S.F.5    Stern, D.M.6    Schmidt, A.M.7
  • 21
    • 0028272883 scopus 로고
    • Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging
    • Vlassara H, Bucala R, Striker L: Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging. Lab Invest, 1994; 70: 138-151.
    • (1994) Lab Invest , vol.70 , pp. 138-151
    • Vlassara, H.1    Bucala, R.2    Striker, L.3
  • 22
    • 0029088742 scopus 로고
    • Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule- 1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes
    • Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J, Cao R, Yan SD, Brett J, Stern D: Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule- 1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest, 1995; 96: 1395-1403.
    • (1995) J Clin Invest , vol.96 , pp. 1395-1403
    • Schmidt, A.M.1    Hori, O.2    Chen, J.X.3    Li, J.F.4    Crandall, J.5    Zhang, J.6    Cao, R.7    Yan, S.D.8    Brett, J.9    Stern, D.10
  • 23
    • 0021691725 scopus 로고
    • Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: Generation of antibodies specific for derivatized lysine
    • Steinbrecher UP, Fisher M, Witztum JL, Curtiss LK: Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: Generation of antibodies specific for derivatized lysine. J Lipid Res, 1984; 25: 1109-1116.
    • (1984) J Lipid Res , vol.25 , pp. 1109-1116
    • Steinbrecher, U.P.1    Fisher, M.2    Witztum, J.L.3    Curtiss, L.K.4
  • 25
    • 0023221153 scopus 로고
    • Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products
    • Steinbrecher UP: Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J Biol Chem, 1987; 262: 3603-3608.
    • (1987) J Biol Chem , vol.262 , pp. 3603-3608
    • Steinbrecher, U.P.1
  • 28
    • 0036435829 scopus 로고    scopus 로고
    • Oxidized LDL-anti-oxidized LDL immune complexes and diabetic nephropathy
    • Atchley DH, Lopes-Virella MF, Zheng D, Virella G: Oxidized LDL-anti-oxidized LDL immune complexes and diabetic nephropathy. Diabetologia, 2002; 45: 1562-1571.
    • (2002) Diabetologia , vol.45 , pp. 1562-1571
    • Atchley, D.H.1    Lopes-Virella, M.F.2    Zheng, D.3    Virella, G.4
  • 29
    • 0038445605 scopus 로고    scopus 로고
    • Lipoprotein autoantibodies: Measurement and significance
    • Virella G, Lopes-Virella MF: Lipoprotein autoantibodies: Measurement and significance. Clin Diagn Lab Immunol, 2003; 10: 499-505.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 499-505
    • Virella, G.1    Lopes-Virella, M.F.2
  • 30
    • 12544253356 scopus 로고    scopus 로고
    • Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies
    • Virella G, Thorpe S, Alderson NL, Derrick MB, Chassereau C, Rhett JM, Lopes-Virella MF: Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies. J Lipid Res, 2004; 45: 1859-1867.
    • (2004) J Lipid Res , vol.45 , pp. 1859-1867
    • Virella, G.1    Thorpe, S.2    Alderson, N.L.3    Derrick, M.B.4    Chassereau, C.5    Rhett, J.M.6    Lopes-Virella, M.F.7
  • 31
    • 0014918785 scopus 로고
    • Autoimmune hyperlipidemia. An atherogenic metabolic disease of immune origin
    • Beaumont J: Autoimmune hyperlipidemia. An atherogenic metabolic disease of immune origin. Rev Eur Stud Clin Biol, 1970; 15: 1037-1041.
    • (1970) Rev Eur Stud Clin Biol , vol.15 , pp. 1037-1041
    • Beaumont, J.1
  • 32
    • 0017811363 scopus 로고
    • Studies on the occurrence of circulating immune complexes in vascular disease
    • Füst G, Szondy E, Szekely J, Nanai I, Gerö S: Studies on the occurrence of circulating immune complexes in vascular disease. Atherosclerosis, 1978; 29: 181-190.
    • (1978) Atherosclerosis , vol.29 , pp. 181-190
    • Füst, G.1    Szondy, E.2    Szekely, J.3    Nanai, I.4    Gerö, S.5
  • 34
    • 0023718536 scopus 로고
    • Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. A possible mechanism of foam cell formation
    • Griffith RL, Virella GT, Stevenson HC, Lopes-Virella MF: Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. A possible mechanism of foam cell formation. J Exp Med, 1988; 168: 1041-1059.
    • (1988) J Exp Med , vol.168 , pp. 1041-1059
    • Griffith, R.L.1    Virella, G.T.2    Stevenson, H.C.3    Lopes-Virella, M.F.4
  • 36
    • 0025800335 scopus 로고
    • Enhanced uptake and impaired intracellular metabolism of low density lipoprotein complexed with anti-low density lipoprotein antibodies
    • Lopes-Virella MF, Griffith RL, Shunk KA, Virella GT: Enhanced uptake and impaired intracellular metabolism of low density lipoprotein complexed with anti-low density lipoprotein antibodies. Arterioscler Thromb, 1991; 11: 1356-1367.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1356-1367
    • Lopes-Virella, M.F.1    Griffith, R.L.2    Shunk, K.A.3    Virella, G.T.4
  • 37
  • 38
  • 39
    • 33748752528 scopus 로고    scopus 로고
    • OxLDL immune complexes activate complement and induce cytokine production by monomac 6 cells and human macrophages
    • Saad AF, Virella G, Chassereau C, Boackle RJ, Lopes- Virella MF: OxLDL immune complexes activate complement and induce cytokine production by monomac 6 cells and human macrophages. J Lipid Res, 2006; 47: 1975-1983.
    • (2006) J Lipid Res , vol.47 , pp. 1975-1983
    • Saad, A.F.1    Virella, G.2    Chassereau, C.3    Boackle, R.J.4    Lopes- virella, M.F.5
  • 40
    • 0033664601 scopus 로고    scopus 로고
    • Fc-gamma receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase
    • Huang Y, Fleming AJ, Wu S, Virella G, Lopes-Virella MF: Fc-gamma receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase. Arterioscler Thromb Vasc Biol, 2000; 20: 2533-2538.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2533-2538
    • Huang, Y.1    Fleming, A.J.2    Wu, S.3    Virella, G.4    Lopes-Virella, M.F.5
  • 41
    • 33845628089 scopus 로고    scopus 로고
    • Anti-oxLDL IgG blocks oxLDL interaction with CD36, but promotes FcgR, CD32a-dependent inflammatory cell adhesion
    • Nagarajan S: Anti-oxLDL IgG blocks oxLDL interaction with CD36, but promotes FcgR, CD32a-dependent inflammatory cell adhesion. Immunol Lett, 2007; 108: 52-61.
    • (2007) Immunol Lett , vol.108 , pp. 52-61
    • Nagarajan, S.1
  • 42
    • 0026739612 scopus 로고
    • Redirected targeting of LDL to human monocyte Fcg receptors with bispecific antibodies
    • Morganelli PM, Kitzmiller TJ, Hemmer R, Fanger MW: Redirected targeting of LDL to human monocyte Fcg receptors with bispecific antibodies. Arterioscler Thromb, 1992; 12: 1131-1138.
    • (1992) Arterioscler Thromb , vol.12 , pp. 1131-1138
    • Morganelli, P.M.1    Kitzmiller, T.J.2    Hemmer, R.3    Fanger, M.W.4
  • 45
    • 0025892826 scopus 로고
    • Erythrocytebound low-density lipoprotein immune complexes lead to cholesteryl ester accumulation in human monocytederived macrophages
    • Gisinger C, Virella GT, Lopes-Virella MF: Erythrocytebound low-density lipoprotein immune complexes lead to cholesteryl ester accumulation in human monocytederived macrophages. Clin Immunol Immunopath, 1991; 59: 37-52.
    • (1991) Clin Immunol Immunopath , vol.59 , pp. 37-52
    • Gisinger, C.1    Virella, G.T.2    Lopes-Virella, M.F.3
  • 46
    • 18644384153 scopus 로고    scopus 로고
    • Pro-atherogenic and pro-inflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL
    • Virella G, Atchley DH, Koskinen S, Zheng D, Lopes- Virella M: Pro-atherogenic and pro-inflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL. Clin Immunol, 2002; 105: 81-92.
    • (2002) Clin Immunol , vol.105 , pp. 81-92
    • Virella, G.1    Atchley, D.H.2    Koskinen, S.3    Zheng, D.4    Lopes- virella, M.5
  • 48
    • 58549119340 scopus 로고    scopus 로고
    • Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells
    • Hammad SM, Twal WO, Barth JL, Smith KJ, Saad AF, Virella G, Argraves WS, Lopes-Virella MF: Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. Atherosclerosis, 2009; 202: 394-404.
    • (2009) Atherosclerosis , vol.202 , pp. 394-404
    • Hammad, S.M.1    Twal, W.O.2    Barth, J.L.3    Smith, K.J.4    Saad, A.F.5    Virella, G.6    Argraves, W.S.7    Lopes-Virella, M.F.8
  • 49
    • 84859313174 scopus 로고    scopus 로고
    • Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: Role in phagocytosis and cytokine release
    • Truman JP, Al Gadban MM, Smith KJ, Jenkins RW, Mayroo N, Virella G, Lopes-Virella MF, Bielawska A, Hannun YA, Hammad SM: Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: Role in phagocytosis and cytokine release. Immunology, 2012; 136: 30-45.
    • (2012) Immunology , vol.136 , pp. 30-45
    • Truman, J.P.1    Al Gadban, M.M.2    Smith, K.J.3    Jenkins, R.W.4    Mayroo, N.5    Virella, G.6    Lopes-Virella, M.F.7    Bielawska, A.8    Hannun, Y.A.9    Hammad, S.M.10
  • 54
    • 0026323623 scopus 로고
    • Macrophages and oxidized low density lipoproteins in the pathogenesis of atherosclerosis
    • Yla-Herttuala S: Macrophages and oxidized low density lipoproteins in the pathogenesis of atherosclerosis. Ann Med, 1991; 23: 561-567.
    • (1991) Ann Med , vol.23 , pp. 561-567
    • Yla-Herttuala, S.1
  • 56
    • 0035144540 scopus 로고    scopus 로고
    • Detection of autoantibodies against advanced glycation endproducts and age-immune complexes in serum of patients with diabetes mellitus
    • Turk Z, Ljubic S, Turk N, Benko B: Detection of autoantibodies against advanced glycation endproducts and age-immune complexes in serum of patients with diabetes mellitus. Clin Chim Acta, 2001; 303.
    • (2001) Clin Chim Acta , pp. 303
    • Turk, Z.1    Ljubic, S.2    Turk, N.3    Benko, B.4
  • 58
    • 0029017015 scopus 로고
    • Malondialdehyde-modified low density lipoproteins in patients with atherosclerotic disease
    • Holvoet P, Perez G, Zhao Z, Brouwers E, Bernar H, Collen D: Malondialdehyde-modified low density lipoproteins in patients with atherosclerotic disease. J Clin Invest, 1995; 95: 2611-2619.
    • (1995) J Clin Invest , vol.95 , pp. 2611-2619
    • Holvoet, P.1    Perez, G.2    Zhao, Z.3    Brouwers, E.4    Bernar, H.5    Collen, D.6
  • 61
    • 0035170772 scopus 로고    scopus 로고
    • Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptordeficient mice
    • Tsimikas S, Palinski W, Witztum JL: Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptordeficient mice. Arterioscler Thromb Vasc Biol, 2001; 21: 95-100.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 95-100
    • Tsimikas, S.1    Palinski, W.2    Witztum, J.L.3
  • 62
    • 0032951483 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus
    • Lopes-Virella MF, Virella G, Orchard TJ, Koskinen S, Evans RW, Becker DJ, Forrest KY: Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus. Clin Immunol, 1999; 90: 165-172.
    • (1999) Clin Immunol , vol.90 , pp. 165-172
    • Lopes-Virella, M.F.1    Virella, G.2    Orchard, T.J.3    Koskinen, S.4    Evans, R.W.5    Becker, D.J.6    Forrest, K.Y.7
  • 63
    • 0031259751 scopus 로고    scopus 로고
    • Anti-modified LDL antibodies and LDL-containing immune complexes in IDDM patients and healthy controls
    • Mironova M, Virella G, Virella-Lowell I, Lopes-Virella MF: Anti-modified LDL antibodies and LDL-containing immune complexes in IDDM patients and healthy controls. Clin Immunol Immunopath, 1997; 85: 73-82.
    • (1997) Clin Immunol Immunopath , vol.85 , pp. 73-82
    • Mironova, M.1    Virella, G.2    Virella-Lowell, I.3    Lopes-Virella, M.F.4
  • 66
    • 0002139616 scopus 로고
    • Use of polyethylene glycol (PEG) to concentrate immune complexes from serum or plasma samples
    • Zubler RH, Perin LH, Creighton WD, Lambert PH: Use of polyethylene glycol (PEG) to concentrate immune complexes from serum or plasma samples. Ann Rheum Dis, 1977; 36 (Suppl.): 23-26.
    • (1977) Ann Rheum Dis , vol.36 , Issue.SUPPL. , pp. 23-26
    • Zubler, R.H.1    Perin, L.H.2    Creighton, W.D.3    Lambert, P.H.4
  • 67
    • 71649089957 scopus 로고    scopus 로고
    • Experimental immunotherapeutic approaches for atherosclerosis
    • Amir S, Binder CJ: Experimental immunotherapeutic approaches for atherosclerosis. Clin Immunol, 2010; 134: 66-79.
    • (2010) Clin Immunol , vol.134 , pp. 66-79
    • Amir, S.1    Binder, C.J.2
  • 68
    • 0031702543 scopus 로고    scopus 로고
    • Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes
    • Freigang S, Horkko S, Miller E, Witztum JL, Palinski W: Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. ArteriosclerThromb Vasc Biol, 1998; 18: 1972-1982.
    • (1998) ArteriosclerThromb Vasc Biol , vol.18 , pp. 1972-1982
    • Freigang, S.1    Horkko, S.2    Miller, E.3    Witztum, J.L.4    Palinski, W.5
  • 69
    • 0029097852 scopus 로고
    • Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis
    • Palinski W, Tangirala RK, Miller E, Young SG, Witztum JL: Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler Thromb Vasc Biol, 1995; 15: 1569-1576.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1569-1576
    • Palinski, W.1    Tangirala, R.K.2    Miller, E.3    Young, S.G.4    Witztum, J.L.5
  • 71
    • 57449096122 scopus 로고    scopus 로고
    • A prescription for human immunology
    • Davis MM: A prescription for human immunology. Immunity, 2008; 29: 835-838.
    • (2008) Immunity , vol.29 , pp. 835-838
    • Davis, M.M.1
  • 72
    • 0041446796 scopus 로고
    • Structure and function of immunoglobulins
    • Glynn LE, Steward MM, eds., New York: J. Wiley and Sons
    • Turner MW: Structure and function of immunoglobulins. In: Glynn LE, Steward MM, eds. Immunochemistry: An advanced textbook. New York: J. Wiley and Sons; 1977: 1-57.
    • (1977) Immunochemistry: An Advanced Textbook , pp. 1-57
    • Turner, M.W.1
  • 73
    • 84886666556 scopus 로고    scopus 로고
    • The complement system
    • Virella G, ed., NY and London: Informa
    • Boackle RJ: The complement system. In: Virella G, ed. Medical immunology. NY and London: Informa; 2007: 93-112.
    • (2007) Medical Immunology , pp. 93-112
    • Boackle, R.J.1
  • 74
    • 0242381313 scopus 로고    scopus 로고
    • Immunoglobulin m type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis
    • Epub 2003 Oct 2106
    • Karvonen J, Paivansalo M, Kesaniemi YA, Horkko S: Immunoglobulin m type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis. Circulation, 2003; 108: 2107-2112. Epub 2003 Oct 2106.
    • (2003) Circulation , vol.108 , pp. 2107-2112
    • Karvonen, J.1    Paivansalo, M.2    Kesaniemi, Y.A.3    Horkko, S.4
  • 75
    • 33746773033 scopus 로고    scopus 로고
    • Antibodies of igm subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
    • Su J, Georgiades A, Wu R, Thulin T, de Faire U, Frostegard J: Antibodies of igm subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension. Atherosclerosis, 2006; 188: 160-166.
    • (2006) Atherosclerosis , vol.188 , pp. 160-166
    • Su, J.1    Georgiades, A.2    Wu, R.3    Thulin, T.4    de Faire, U.5    Frostegard, J.6
  • 77
    • 34247553751 scopus 로고    scopus 로고
    • Association between igm against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease
    • Fredrikson GN, Hedblad B, Berglund G, Alm R, Nilsson JA, Schiopu A, Shah PK, Nilsson J: Association between igm against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease. Stroke, 2007; 38: 1495-1500.
    • (2007) Stroke , vol.38 , pp. 1495-1500
    • Fredrikson, G.N.1    Hedblad, B.2    Berglund, G.3    Alm, R.4    Nilsson, J.A.5    Schiopu, A.6    Shah, P.K.7    Nilsson, J.8
  • 82
    • 49149122536 scopus 로고    scopus 로고
    • The oxidation ratio of LDL: A predictor for coronary artery disease
    • Huang H, Mai W, Liu D, Hao Y, Tao J, Dong Y: The oxidation ratio of LDL: A predictor for coronary artery disease. Dis Markers, 2008; 24: 341-349.
    • (2008) Dis Markers , vol.24 , pp. 341-349
    • Huang, H.1    Mai, W.2    Liu, D.3    Hao, Y.4    Tao, J.5    Dong, Y.6
  • 86
    • 34648839885 scopus 로고    scopus 로고
    • The relationship between oxidized LDL and other cardiovascular risk factors and subclinical cvd in different ethnic groups: The multi-ethnic study of atherosclerosis (mesa)
    • Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR: The relationship between oxidized LDL and other cardiovascular risk factors and subclinical cvd in different ethnic groups: The multi-ethnic study of atherosclerosis (mesa). Atherosclerosis, 2007; 194: 245-252.
    • (2007) Atherosclerosis , vol.194 , pp. 245-252
    • Holvoet, P.1    Jenny, N.S.2    Schreiner, P.J.3    Tracy, R.P.4    Jacobs, D.R.5
  • 87
    • 0021677967 scopus 로고
    • Circulating immune complexes, immunoglobulins, complement, antibodies to dietary antigens, cholesterol and lipoproteins levels in patients with occlusive coronary lesions
    • Romano EL, Sotolongo-Pons M, Camejo G, Soyano A: Circulating immune complexes, immunoglobulins, complement, antibodies to dietary antigens, cholesterol and lipoproteins levels in patients with occlusive coronary lesions. Atherosclerosis, 1984; 53: 119-128.
    • (1984) Atherosclerosis , vol.53 , pp. 119-128
    • Romano, E.L.1    Sotolongo-Pons, M.2    Camejo, G.3    Soyano, A.4
  • 88
  • 93
    • 0029003223 scopus 로고
    • Detection of autoantibodies against oxidized lowdensity lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease
    • Boullier A, Hamon M, Walters-Laporte E, Martin- Nizart F, Mackereel R, Fruchart JC, Bertrand M, Duriez P: Detection of autoantibodies against oxidized lowdensity lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease. Clin Chim Acta, 1995; 238: 1-10.
    • (1995) Clin Chim Acta , vol.238 , pp. 1-10
    • Boullier, A.1    Hamon, M.2    Walters-Laporte, E.3    Martin-Nizart, F.4    Mackereel, R.5    Fruchart, J.C.6    Bertrand, M.7    Duriez, P.8
  • 94
    • 0032950484 scopus 로고    scopus 로고
    • Autoantibodies to oxLDL are decreased in individuals with borderline hypertension
    • Wu R, de Faire U, Lemne C, Witztum JL, Frostegard J: Autoantibodies to oxLDL are decreased in individuals with borderline hypertension. Hypertension, 1999; 33: 53-59.
    • (1999) Hypertension , vol.33 , pp. 53-59
    • Wu, R.1    de Faire, U.2    Lemne, C.3    Witztum, J.L.4    Frostegard, J.5
  • 95
    • 0018951925 scopus 로고
    • Rheumatoid factor in acute viral infections: Interference with determination of IgM, IgG, and IgA antibodies in an enzyme immunoassay
    • Salonen E-M, Vaheri A, Suni J, Wagger O: Rheumatoid factor in acute viral infections: Interference with determination of IgM, IgG, and IgA antibodies in an enzyme immunoassay J Inf Dis, 1980; 142: 250-255.
    • (1980) J Inf Dis , vol.142 , pp. 250-255
    • Salonen, E.-M.1    Vaheri, A.2    Suni, J.3    Wagger, O.4
  • 97
    • 0037419857 scopus 로고    scopus 로고
    • Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes
    • Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E, Juliano J, Witztum JL: Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J Am Coll Cardiol, 2003; 41: 360-370.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 360-370
    • Tsimikas, S.1    Bergmark, C.2    Beyer, R.W.3    Patel, R.4    Pattison, J.5    Miller, E.6    Juliano, J.7    Witztum, J.L.8
  • 98
    • 4544346640 scopus 로고    scopus 로고
    • High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein bB-100 in patients with acute coronary syndromes in the miracl trial
    • Tsimikas S, Witztum JL, Miller ER, Sasiela WJ, Szarek M, Olsson AG, Schwartz GG: High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein bB-100 in patients with acute coronary syndromes in the miracl trial. Circulation, 2004; 110: 1406-1412.
    • (2004) Circulation , vol.110 , pp. 1406-1412
    • Tsimikas, S.1    Witztum, J.L.2    Miller, E.R.3    Sasiela, W.J.4    Szarek, M.5    Olsson, A.G.6    Schwartz, G.G.7
  • 99
    • 33846102942 scopus 로고    scopus 로고
    • Immune complexes containing modified lipoproteins are related to the progression of internal carotid intimamedia thickness in patients with type 1 diabetes
    • Lopes-Virella MF, McHenry MB, Lipsitz S, Yim E, Wilson PF, Lackland DT, Lyons T, Jenkins AJ, Virella G: Immune complexes containing modified lipoproteins are related to the progression of internal carotid intimamedia thickness in patients with type 1 diabetes. Atherosclerosis, 2007; 190: 359-369.
    • (2007) Atherosclerosis , vol.190 , pp. 359-369
    • Lopes-Virella, M.F.1    McHenry, M.B.2    Lipsitz, S.3    Yim, E.4    Wilson, P.F.5    Lackland, D.T.6    Lyons, T.7    Jenkins, A.J.8    Virella, G.9
  • 100
    • 79551586291 scopus 로고    scopus 로고
    • The levels of oxidized LDL and age- LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes
    • Lopes-Virella MF, Hunt KJ, Baker NL, Lachin J, Nathan DM, Virella G: The levels of oxidized LDL and age- LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes. Diabetes, 2011; 60: 582-589.
    • (2011) Diabetes , vol.60 , pp. 582-589
    • Lopes-Virella, M.F.1    Hunt, K.J.2    Baker, N.L.3    Lachin, J.4    Nathan, D.M.5    Virella, G.6
  • 102
    • 0032514728 scopus 로고    scopus 로고
    • Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease
    • Holvoet P, Vanhaecke J, Janssens S, Van de Werf F, Collen D: Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation, 1998; 98: 1487-1494.
    • (1998) Circulation , vol.98 , pp. 1487-1494
    • Holvoet, P.1    Vanhaecke, J.2    Janssens, S.3    Van de Werf, F.4    Collen, D.5
  • 104
    • 84861783204 scopus 로고    scopus 로고
    • group DEs: High concentrations of age-LDL and oxidized LDL in circulating immune complexes is associated with progression of retinopathy in type 1 diabetes
    • Lopes-Virella MF, Baker N, Hunt K, Lyons T.A. J, Virella G, group DEs: High concentrations of age-LDL and oxidized LDL in circulating immune complexes is associated with progression of retinopathy in type 1 diabetes. Diabetes care, 2012; 35: 1333-1340.
    • (2012) Diabetes Care , vol.35 , pp. 1333-1340
    • Lopes-Virella, M.F.1    Baker, N.2    Hunt, K.3    Lyons, T.A.J.4    Virella, G.5
  • 105
    • 45249087013 scopus 로고    scopus 로고
    • Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy
    • Virella G, Carter RE, Saad A, Crosswell EG, Game BA, Lopes-Virella MF: Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy. Clin Immunol, 2008; 127: 394-400
    • (2008) Clin Immunol , vol.127 , pp. 394-400
    • Virella, G.1    Carter, R.E.2    Saad, A.3    Crosswell, E.G.4    Game, B.A.5    Lopes-Virella, M.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.