Computational study of the "DFG-Flip" conformational transition in c-Abl and c-Src tyrosine kinases

Journal of Physical Chemistry B

Volumn 119, Issue 4, 2015, Pages 1443-1456

  Meng, Yilin ^a   Lin, Yen Lin ^a   Roux, Benoît ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL SIGNALING; ENZYMES; FREE ENERGY; SIGNAL TRANSDUCTION;

CELLULAR SIGNAL TRANSDUCTION; CELLULAR SIGNALING; COMPUTATIONAL STUDIES; CONFORMATIONAL TRANSITIONS; FREE ENERGY LANDSCAPE; PROTEIN TYROSINE KINASE; STRUCTURAL DIFFERENCES; THERMODYNAMIC FACTORS;

CONFORMATIONS;

ABELSON KINASE; DFG PEPTIDE; OLIGOPEPTIDE; PROTEIN TYROSINE KINASE;

CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER SIMULATION; MOLECULAR MODEL; PROTEIN CONFORMATION;

COMPUTER SIMULATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-ABL; SRC-FAMILY KINASES;

EID: 84921901999     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp511792a     Document Type: Article

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