Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

Journal of the American Society of Nephrology

Volumn 25, Issue 10, 2014, Pages 2201-2212

  Tran, Pamela V ^a,b   Talbott, George C ^a   Turbe Doan, Annick ^a   Jacobs, Damon T ^b   Schonfeld, Michael P ^b   Silva, Luciane M ^b   Chatterjee, Anindita ^b   Prysak, Mary ^a   Allard, Bailey A ^b   Beier, David R ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; THM1 PROTEIN, MOUSE; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE DELETION; GENE INTERACTION; KIDNEY CELL; KIDNEY POLYCYSTIC DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; THM1 GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; FEMALE; GENETICS; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; FEMALE; HEDGEHOG PROTEINS; IN VITRO TECHNIQUES; KIDNEY DISEASES, CYSTIC; MALE; MICE; MICE, KNOCKOUT; TRPP CATION CHANNELS; WNT PROTEINS;

EID: 84921802641     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013070735     Document Type: Article

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