Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity

Journal of Clinical Investigation

Volumn 122, Issue 11, 2012, Pages 4257-4273

  Hopp, Katharina ^a   Ward, Christopher J ^b   Hommerding, Cynthia J ^b   Nasr, Samih H ^b   Tuan, Han Fang ^a   Gainullin, Vladimir G ^a   Rossetti, Sandro ^b   Torres, Vicente E ^b   Harris, Peter C ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCYSTIN 1;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EUKARYOTIC FLAGELLUM; FEMALE; GENE TARGETING; GENETIC VARIABILITY; KIDNEY POLYCYSTIC DISEASE; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; GENETIC LOCI; MICE; MUTATION, MISSENSE; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PROTEIN FOLDING; SEVERITY OF ILLNESS INDEX; TRPP CATION CHANNELS;

EID: 84868613964     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI64313     Document Type: Article

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