Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 4, 2011, Pages 1456-1461

  Qin, Jian ^a   Lin, Yulian ^a   Norman, Ryan X ^a   Ko, Hyuk W ^a,b   Eggenschwiler, Jonathan T ^a  

^a PRINCETON UNIVERSITY   (United States)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

Axoneme; Cytoplasmic dynein 2; Kinesin 2; Neural patterning

Indexed keywords

CARRIER PROTEIN; INTRAFLAGELLAR TRANSPORT PROTEIN 122; PROTEIN SISTER OF OPEN BRAIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR TULP3; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; EUKARYOTIC FLAGELLUM; FLAGELLUM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CILIA; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HEDGEHOG PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

ERINACEIDAE; MAMMALIA;

EID: 79952171642     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1011410108     Document Type: Article

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