-
1
-
-
84871460710
-
The structure of native influenza virion ribonucleoproteins
-
Arranz R, Coloma R, Chichon FJ, Conesa JJ, Carrascosa JL, Valpuesta JM, Ortin J, Martin- Benito J (2012) The structure of native influenza virion ribonucleoproteins. Science 338(6114):1634–1637
-
(2012)
Science
, vol.338
, Issue.6114
, pp. 1634-1637
-
-
Arranz, R.1
Coloma, R.2
Chichon, F.J.3
Conesa, J.J.4
Carrascosa, J.L.5
Valpuesta, J.M.6
Ortin, J.7
Martin- Benito, J.8
-
2
-
-
0035964342
-
Electrostatics of nanosystems: Application to microtubules and the ribosome
-
Baker NA, Sept D, Joseph S, Holst MJ, McCammon JA (2001) Electrostatics of nanosystems: application to microtubules and the ribosome. Proc Natl Acad Sci U S A 98(18):10037–10041
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.18
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
3
-
-
0028118520
-
Mutational analysis of the conserved motifs of influenza a virus polymerase basic protein 1
-
Biswas SK, Nayak DP (1994) Mutational analysis of the conserved motifs of influenza a virus polymerase basic protein 1. J Virol 68(3):1819–1826
-
(1994)
J Virol
, vol.68
, Issue.3
, pp. 1819-1826
-
-
Biswas, S.K.1
Nayak, D.P.2
-
4
-
-
80054995402
-
Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein
-
Bogs J, Kalthoff D, Veits J, Pavlova S, Schwemmle M, Manz B, Mettenleiter TC, Stech J (2011) Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein. J Virol 85(20):10691–10698
-
(2011)
J Virol
, vol.85
, Issue.20
, pp. 10691-10698
-
-
Bogs, J.1
Kalthoff, D.2
Veits, J.3
Pavlova, S.4
Schwemmle, M.5
Manz, B.6
Mettenleiter, T.C.7
Stech, J.8
-
5
-
-
79953224896
-
Interaction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly
-
Boivin S, Hart DJ (2011) Interaction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly. J Biol Chem 286(12):10439–10448
-
(2011)
J Biol Chem
, vol.286
, Issue.12
, pp. 10439-10448
-
-
Boivin, S.1
Hart, D.J.2
-
6
-
-
80052576674
-
Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins
-
Bortz E, Westera L, Maamary J, Steel J, Albrecht RA, Manicassamy B, Chase G, Martinez- Sobrido L, Schwemmle M, Garcia-Sastre A (2011) Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. MBio 2(4):e00151–11
-
(2011)
Mbio
, vol.2
, Issue.4
-
-
Bortz, E.1
Westera, L.2
Maamary, J.3
Steel, J.4
Albrecht, R.A.5
Manicassamy, B.6
Chase, G.7
Martinez- Sobrido, L.8
Schwemmle, M.9
Garcia-Sastre, A.10
-
7
-
-
80052274996
-
Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors
-
Bradel-Tretheway BG, Mattiacio JL, Krasnoselsky A, Stevenson C, Purdy D, Dewhurst S, Katze MG (2011) Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors. J Virol 85(17):8569–8581
-
(2011)
J Virol
, vol.85
, Issue.17
, pp. 8569-8581
-
-
Bradel-Tretheway, B.G.1
Mattiacio, J.L.2
Krasnoselsky, A.3
Stevenson, C.4
Purdy, D.5
Dewhurst, S.6
Katze, M.G.7
-
8
-
-
72549116887
-
The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus
-
Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ (2009) The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell 139(7):1243–1254
-
(2009)
Cell
, vol.139
, Issue.7
, pp. 1243-1254
-
-
Brass, A.L.1
Huang, I.C.2
Benita, Y.3
John, S.P.4
Krishnan, M.N.5
Feeley, E.M.6
Ryan, B.J.7
Weyer, J.L.8
Van Der Weyden, L.9
Fikrig, E.10
Adams, D.J.11
Xavier, R.J.12
Farzan, M.13
Elledge, S.J.14
-
9
-
-
0035811003
-
Pattern of mutation in the genome of influenza a virus on adaptation to increased virulence in the mouse lung: Identification of functional themes
-
Brown EG, Liu H, Kit LC, Baird S, Nesrallah M (2001) Pattern of mutation in the genome of influenza a virus on adaptation to increased virulence in the mouse lung: identification of functional themes. Proc Natl Acad Sci U S A 98(12):6883–6888
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.12
, pp. 6883-6888
-
-
Brown, E.G.1
Liu, H.2
Kit, L.C.3
Baird, S.4
Nesrallah, M.5
-
10
-
-
77950835010
-
PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells
-
Bussey KA, Bousse TL, Desmet EA, Kim B, Takimoto T (2010) PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells. J Virol 84(9):4395–4406
-
(2010)
J Virol
, vol.84
, Issue.9
, pp. 4395-4406
-
-
Bussey, K.A.1
Bousse, T.L.2
Desmet, E.A.3
Kim, B.4
Takimoto, T.5
-
11
-
-
30044445273
-
Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses
-
Carr SM, Carnero E, Garcia-Sastre A, Brownlee GG, Fodor E (2006) Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses. Virology 344(2): 492–508
-
(2006)
Virology
, vol.344
, Issue.2
, pp. 492-508
-
-
Carr, S.M.1
Carnero, E.2
Garcia-Sastre, A.3
Brownlee, G.G.4
Fodor, E.5
-
12
-
-
84871969763
-
Unstable polymerase-nucleoprotein interaction is not responsible for avian influenza virus polymerase restriction in human cells
-
Cauldwell AV, Moncorge O, Barclay WS (2013) Unstable polymerase-nucleoprotein interaction is not responsible for avian influenza virus polymerase restriction in human cells. J Virol 87(2):1278–1284
-
(2013)
J Virol
, vol.87
, Issue.2
, pp. 1278-1284
-
-
Cauldwell, A.V.1
Moncorge, O.2
Barclay, W.S.3
-
14
-
-
77953794395
-
Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities
-
Chan WH, Ng AK, Robb NC, Lam MK, Chan PK, Au SW, Wang JH, Fodor E, Shaw PC (2010) Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities. J Virol 84(14):7337–7345
-
(2010)
J Virol
, vol.84
, Issue.14
, pp. 7337-7345
-
-
Chan, W.H.1
Ng, A.K.2
Robb, N.C.3
Lam, M.K.4
Chan, P.K.5
Au, S.W.6
Wang, J.H.7
Fodor, E.8
Shaw, P.C.9
-
15
-
-
0035658084
-
A novel influenza a virus mitochondrial protein that induces cell death
-
Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, Basta S, O’Neill R, Schickli J, Palese P, Henklein P, Bennink JR, Yewdell JW (2001) A novel influenza a virus mitochondrial protein that induces cell death. Nat Med 7(12):1306–1312
-
(2001)
Nat Med
, vol.7
, Issue.12
, pp. 1306-1312
-
-
Chen, W.1
Calvo, P.A.2
Malide, D.3
Gibbs, J.4
Schubert, U.5
Bacik, I.6
Basta, S.7
O’Neill, R.8
Schickli, J.9
Palese, P.10
Henklein, P.11
Bennink, J.R.12
Yewdell, J.W.13
-
16
-
-
84878336274
-
Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: Clinical analysis and characterisation of viral genome
-
Chen Y, Liang W, Yang S, Wu N, Gao H, Sheng J, Yao H, Wo J, Fang Q, Cui D, Li Y, Yao X, Zhang Y, Wu H, Zheng S, Diao H, Xia S, Chan KH, Tsoi HW, Teng JL, Song W, Wang P, Lau SY, Zheng M, Chan JF, To KK, Chen H, Li L, Yuen KY (2013) Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome. Lancet 381(9881):1916–1925
-
(2013)
Lancet
, vol.381
, Issue.9881
, pp. 1916-1925
-
-
Chen, Y.1
Liang, W.2
Yang, S.3
Wu, N.4
Gao, H.5
Sheng, J.6
Yao, H.7
Wo, J.8
Fang, Q.9
Cui, D.10
Li, Y.11
Yao, X.12
Zhang, Y.13
Wu, H.14
Zheng, S.15
Diao, H.16
Xia, S.17
Chan, K.H.18
Tsoi, H.W.19
Teng, J.L.20
Song, W.21
Wang, P.22
Lau, S.Y.23
Zheng, M.24
Chan, J.F.25
To, K.K.26
Chen, H.27
Li, L.28
Yuen, K.Y.29
more..
-
17
-
-
84894063527
-
Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: A descriptive study
-
Chen H, Yuan H, Gao R, Zhang J, Wang D, Xiong Y, Fan G, Yang F, Li X, Zhou J, Zou S, Yang L, Chen T, Dong L, Bo H, Zhao X, Zhang Y, Lan Y, Bai T, Dong J, Li Q, Wang S, Li H, Gong T, Shi Y, Ni X, Li J, Fan J, Wu J, Zhou X, Hu M, Wan J, Yang W, Li D, Wu G, Feng Z, Gao GF, Wang Y, Jin Q, Liu M, Shu Y (2014) Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. Lancet 383:714–721
-
(2014)
Lancet
, vol.383
, pp. 714-721
-
-
Chen, H.1
Yuan, H.2
Gao, R.3
Zhang, J.4
Wang, D.5
Xiong, Y.6
Fan, G.7
Yang, F.8
Li, X.9
Zhou, J.10
Zou, S.11
Yang, L.12
Chen, T.13
Dong, L.14
Bo, H.15
Zhao, X.16
Zhang, Y.17
Lan, Y.18
Bai, T.19
Dong, J.20
Li, Q.21
Wang, S.22
Li, H.23
Gong, T.24
Shi, Y.25
Ni, X.26
Li, J.27
Fan, J.28
Wu, J.29
Zhou, X.30
Hu, M.31
Wan, J.32
Yang, W.33
Li, D.34
Wu, G.35
Feng, Z.36
Gao, G.F.37
Wang, Y.38
Jin, Q.39
Liu, M.40
Shu, Y.41
more..
-
18
-
-
0036935390
-
Differential effect of nucleotide substitutions in the 3’ arm of the influenza A virus vRNA promoter on transcription/ replication by avian and human polymerase complexes is related to the nature of PB2 amino acid 627
-
Crescenzo-Chaigne B, van der Werf S, Naffakh N (2002) Differential effect of nucleotide substitutions in the 3’ arm of the influenza A virus vRNA promoter on transcription/ replication by avian and human polymerase complexes is related to the nature of PB2 amino acid 627. Virology 303(2):240–252
-
(2002)
Virology
, vol.303
, Issue.2
, pp. 240-252
-
-
Crescenzo-Chaigne, B.1
Van Der Werf, S.2
Naffakh, N.3
-
19
-
-
33749511112
-
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
-
de Jong MD, Simmons CP, Thanh TT, Hien VM, Smith GJ, Chau TN, Hoang DM, Chau NV, Khanh TH, Dong VC, Qui PT, Cam BV, Ha do Q, Guan Y, Peiris JS, Chinh NT, Hien TT, Farrar J (2006) Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med 12(10):1203–1207
-
(2006)
Nat Med
, vol.12
, Issue.10
, pp. 1203-1207
-
-
De Jong, M.D.1
Simmons, C.P.2
Thanh, T.T.3
Hien, V.M.4
Smith, G.J.5
Chau, T.N.6
Hoang, D.M.7
Chau, N.V.8
Khanh, T.H.9
Dong, V.C.10
Qui, P.T.11
Cam, B.V.12
Ha Do, Q.13
Guan, Y.14
Peiris, J.S.15
Chinh, N.T.16
Hien, T.T.17
Farrar, J.18
-
20
-
-
33845406669
-
Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex
-
Deng T, Engelhardt OG, Thomas B, Akoulitchev AV, Brownlee GG, Fodor E (2006) Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex. J Virol 80(24):11911–11919
-
(2006)
J Virol
, vol.80
, Issue.24
, pp. 11911-11919
-
-
Deng, T.1
Engelhardt, O.G.2
Thomas, B.3
Akoulitchev, A.V.4
Brownlee, G.G.5
Fodor, E.6
-
21
-
-
67249130012
-
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
-
Dias A, Bouvier D, Crepin T, McCarthy AA, Hart DJ, Baudin F, Cusack S, Ruigrok RW (2009) The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Nature 458(7240):914–918
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 914-918
-
-
Dias, A.1
Bouvier, D.2
Crepin, T.3
McCarthy, A.A.4
Hart, D.J.5
Baudin, F.6
Cusack, S.7
Ruigrok, R.W.8
-
22
-
-
17444430403
-
Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II
-
Engelhardt OG, Smith M, Fodor E (2005) Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II. J Virol 79(9):5812–5818
-
(2005)
J Virol
, vol.79
, Issue.9
, pp. 5812-5818
-
-
Engelhardt, O.G.1
Smith, M.2
Fodor, E.3
-
23
-
-
84880367286
-
The RNA polymerase of influenza a virus: Mechanisms of viral transcription and replication
-
Fodor E (2013) The RNA polymerase of influenza a virus: mechanisms of viral transcription and replication. Acta Virol 57(2):113–122
-
(2013)
Acta Virol
, vol.57
, Issue.2
, pp. 113-122
-
-
Fodor, E.1
-
24
-
-
4143148582
-
The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza a virus RNA polymerase complex
-
Fodor E, Smith M (2004) The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza a virus RNA polymerase complex. J Virol 78(17):9144–9153
-
(2004)
J Virol
, vol.78
, Issue.17
, pp. 9144-9153
-
-
Fodor, E.1
Smith, M.2
-
25
-
-
79959307361
-
Influence of PB2 host-range determinants on the intranuclear mobility of the influenza a virus polymerase
-
Foeglein A, Loucaides EM, Mura M, Wise HM, Barclay WS, Digard P (2011) Influence of PB2 host-range determinants on the intranuclear mobility of the influenza a virus polymerase. J Gen Virol 92(Pt 7):1650–1661
-
(2011)
J Gen Virol
, vol.92
, pp. 1650-1661
-
-
Foeglein, A.1
Loucaides, E.M.2
Mura, M.3
Wise, H.M.4
Barclay, W.S.5
Digard, P.6
-
26
-
-
70350330586
-
A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice
-
Fornek JL, Gillim-Ross L, Santos C, Carter V, Ward JM, Cheng LI, Proll S, Katze MG, Subbarao K (2009) A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice. J Virol 83(21):11102–11115
-
(2009)
J Virol
, vol.83
, Issue.21
, pp. 11102-11115
-
-
Fornek, J.L.1
Gillim-Ross, L.2
Santos, C.3
Carter, V.4
Ward, J.M.5
Cheng, L.I.6
Proll, S.7
Katze, M.G.8
Subbarao, K.9
-
27
-
-
10744224732
-
Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
-
Fouchier RA, Schneeberger PM, Rozendaal FW, Broekman JM, Kemink SA, Munster V, Kuiken T, Rimmelzwaan GF, Schutten M, Van Doornum GJ, Koch G, Bosman A, Koopmans M, Osterhaus AD (2004) Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. Proc Natl Acad Sci U S A 101(5):1356–1361
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.5
, pp. 1356-1361
-
-
Fouchier, R.A.1
Schneeberger, P.M.2
Rozendaal, F.W.3
Broekman, J.M.4
Kemink, S.A.5
Munster, V.6
Kuiken, T.7
Rimmelzwaan, G.F.8
Schutten, M.9
Van Doornum, G.J.10
Koch, G.11
Bosman, A.12
Koopmans, M.13
Osterhaus, A.D.14
-
28
-
-
33845196953
-
Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates
-
Friedrich B, Quensel C, Sommer T, Hartmann E, Kohler M (2006) Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates. Mol Cell Biol 26(23):8697–8709
-
(2006)
Mol Cell Biol
, vol.26
, Issue.23
, pp. 8697-8709
-
-
Friedrich, B.1
Quensel, C.2
Sommer, T.3
Hartmann, E.4
Kohler, M.5
-
29
-
-
29444438899
-
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host
-
Gabriel G, Dauber B, Wolff T, Planz O, Klenk HD, Stech J (2005) The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Proc Natl Acad Sci U S A 102(51):18590–18595
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.51
, pp. 18590-18595
-
-
Gabriel, G.1
Dauber, B.2
Wolff, T.3
Planz, O.4
Klenk, H.D.5
Stech, J.6
-
30
-
-
40349113426
-
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza a virus
-
Gabriel G, Herwig A, Klenk HD (2008) Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza a virus. PLoS Pathog 4(2):e11
-
(2008)
Plos Pathog
, vol.4
, Issue.2
-
-
Gabriel, G.1
Herwig, A.2
Klenk, H.D.3
-
31
-
-
78751622104
-
Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus
-
Gabriel G, Klingel K, Otte A, Thiele S, Hudjetz B, Arman-Kalcek G, Sauter M, Shmidt T, Rother F, Baumgarte S, Keiner B, Hartmann E, Bader M, Brownlee GG, Fodor E, Klenk HD (2011) Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus. Nat Commun 2:156
-
(2011)
Nat Commun
, vol.2
-
-
Gabriel, G.1
Klingel, K.2
Otte, A.3
Thiele, S.4
Hudjetz, B.5
Arman-Kalcek, G.6
Sauter, M.7
Shmidt, T.8
Rother, F.9
Baumgarte, S.10
Keiner, B.11
Hartmann, E.12
Bader, M.13
Brownlee, G.G.14
Fodor, E.15
Klenk, H.D.16
-
32
-
-
84887623342
-
Adaptive mutations in the H5N1 polymerase complex
-
Gabriel G, Czudai-Matwich V, Klenk HD (2013) Adaptive mutations in the H5N1 polymerase complex. Virus Res 178(1):53–62
-
(2013)
Virus Res
, vol.178
, Issue.1
, pp. 53-62
-
-
Gabriel, G.1
Czudai-Matwich, V.2
Klenk, H.D.3
-
33
-
-
74549123629
-
Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host
-
Gao Y, Zhang Y, Shinya K, Deng G, Jiang Y, Li Z, Guan Y, Tian G, Li Y, Shi J, Liu L, Zeng X, Bu Z, Xia X, Kawaoka Y, Chen H (2009) Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host. PLoS Pathog 5(12):e1000709
-
(2009)
Plos Pathog
, vol.5
, Issue.12
-
-
Gao, Y.1
Zhang, Y.2
Shinya, K.3
Deng, G.4
Jiang, Y.5
Li, Z.6
Guan, Y.7
Tian, G.8
Li, Y.9
Shi, J.10
Liu, L.11
Zeng, X.12
Bu, Z.13
Xia, X.14
Kawaoka, Y.15
Chen, H.16
-
34
-
-
67650407532
-
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
-
Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X, Skepner E, Deyde V, Okomo-Adhiambo M, Gubareva L, Barnes J, Smith CB, Emery SL, Hillman MJ, Rivailler P, Smagala J, de Graaf M, Burke DF, Fouchier RA, Pappas C, Alpuche-Aranda CM, Lopez-Gatell H, Olivera H, Lopez I, Myers CA, Faix D, Blair PJ, Yu C, Keene KM, Dotson PD Jr, Boxrud D, Sambol AR, Abid SH, St George K, Bannerman T, Moore AL, Stringer DJ, Blevins P, Demmler-Harrison GJ, Ginsberg M, Kriner P, Waterman S, Smole S, Guevara HF, Belongia EA, Clark PA, Beatrice ST, Donis R, Katz J, Finelli L, Bridges CB, Shaw M, Jernigan DB, Uyeki TM, Smith DJ, Klimov AI, Cox NJ (2009) Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 325(5937):197–201
-
(2009)
Science
, vol.325
, Issue.5937
, pp. 197-201
-
-
Garten, R.J.1
Davis, C.T.2
Russell, C.A.3
Shu, B.4
Lindstrom, S.5
Balish, A.6
Sessions, W.M.7
Xu, X.8
Skepner, E.9
Deyde, V.10
Okomo-Adhiambo, M.11
Gubareva, L.12
Barnes, J.13
Smith, C.B.14
Emery, S.L.15
Hillman, M.J.16
Rivailler, P.17
Smagala, J.18
De Graaf, M.19
Burke, D.F.20
Fouchier, R.A.21
Pappas, C.22
Alpuche-Aranda, C.M.23
Lopez-Gatell, H.24
Olivera, H.25
Lopez, I.26
Myers, C.A.27
Faix, D.28
Blair, P.J.29
Yu, C.30
Keene, K.M.31
Dotson, P.D.32
Boxrud, D.33
Sambol, A.R.34
Abid, S.H.35
St George, K.36
Bannerman, T.37
Moore, A.L.38
Stringer, D.J.39
Blevins, P.40
Demmler-Harrison, G.J.41
Ginsberg, M.42
Kriner, P.43
Waterman, S.44
Smole, S.45
Guevara, H.F.46
Belongia, E.A.47
Clark, P.A.48
Beatrice, S.T.49
Donis, R.50
Katz, J.51
Finelli, L.52
Bridges, C.B.53
Shaw, M.54
Jernigan, D.B.55
Uyeki, T.M.56
Smith, D.J.57
Klimov, A.I.58
Cox, N.J.59
more..
-
35
-
-
77956634918
-
The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon
-
Graef KM, Vreede FT, Lau YF, McCall AW, Carr SM, Subbarao K, Fodor E (2010) The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon. J Virol 84(17):8433–8445
-
(2010)
J Virol
, vol.84
, Issue.17
, pp. 8433-8445
-
-
Graef, K.M.1
Vreede, F.T.2
Lau, Y.F.3
McCall, A.W.4
Carr, S.M.5
Subbarao, K.6
Fodor, E.7
-
36
-
-
43249128376
-
The structural basis for cap binding by influenza virus polymerase subunit PB2
-
Guilligay D, Tarendeau F, Resa-Infante P, Coloma R, Crepin T, Sehr P, Lewis J, Ruigrok RW, Ortin J, Hart DJ, Cusack S (2008) The structural basis for cap binding by influenza virus polymerase subunit PB2. Nat Struct Mol Biol 15(5):500–506
-
(2008)
Nat Struct Mol Biol
, vol.15
, Issue.5
, pp. 500-506
-
-
Guilligay, D.1
Tarendeau, F.2
Resa-Infante, P.3
Coloma, R.4
Crepin, T.5
Sehr, P.6
Lewis, J.7
Ruigrok, R.W.8
Ortin, J.9
Hart, D.J.10
Cusack, S.11
-
37
-
-
54449099369
-
The multifunctional NS1 protein of influenza a viruses
-
Hale BG, Randall RE, Ortin J, Jackson D (2008) The multifunctional NS1 protein of influenza a viruses. J Gen Virol 89(Pt 10):2359–2376
-
(2008)
J Gen Virol
, vol.89
, pp. 2359-2376
-
-
Hale, B.G.1
Randall, R.E.2
Ortin, J.3
Jackson, D.4
-
38
-
-
49649127852
-
Drosophila RNAi screen identifies host genes important for influenza virus replication
-
Hao L, Sakurai A, Watanabe T, Sorensen E, Nidom CA, Newton MA, Ahlquist P, Kawaoka Y (2008) Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature 454(7206):890–893
-
(2008)
Nature
, vol.454
, Issue.7206
, pp. 890-893
-
-
Hao, L.1
Sakurai, A.2
Watanabe, T.3
Sorensen, E.4
Nidom, C.A.5
Newton, M.A.6
Ahlquist, P.7
Kawaoka, Y.8
-
39
-
-
0035823083
-
Molecular basis for high virulence of Hong Kong H5N1 influenza a viruses
-
Hatta M, Gao P, Halfmann P, Kawaoka Y (2001) Molecular basis for high virulence of Hong Kong H5N1 influenza a viruses. Science 293(5536):1840–1842
-
(2001)
Science
, vol.293
, Issue.5536
, pp. 1840-1842
-
-
Hatta, M.1
Gao, P.2
Halfmann, P.3
Kawaoka, Y.4
-
40
-
-
36049011840
-
Growth of H5N1 influenza a viruses in the upper respiratory tracts of mice
-
Hatta M, Hatta Y, Kim JH, Watanabe S, Shinya K, Nguyen T, Lien PS, Le QM, Kawaoka Y (2007) Growth of H5N1 influenza a viruses in the upper respiratory tracts of mice. PLoS Pathog 3(10):1374–1379
-
(2007)
Plos Pathog
, vol.3
, Issue.10
, pp. 1374-1379
-
-
Hatta, M.1
Hatta, Y.2
Kim, J.H.3
Watanabe, S.4
Shinya, K.5
Nguyen, T.6
Lien, P.S.7
Le, Q.M.8
Kawaoka, Y.9
-
41
-
-
50649089174
-
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus
-
He X, Zhou J, Bartlam M, Zhang R, Ma J, Lou Z, Li X, Li J, Joachimiak A, Zeng Z, Ge R, Rao Z, Liu Y (2008) Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature 454(7208):1123–1126
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1123-1126
-
-
He, X.1
Zhou, J.2
Bartlam, M.3
Zhang, R.4
Ma, J.5
Lou, Z.6
Li, X.7
Li, J.8
Joachimiak, A.9
Zeng, Z.10
Ge, R.11
Rao, Z.12
Liu, Y.13
-
42
-
-
77950472820
-
Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission
-
Herfst S, Chutinimitkul S, Ye J, de Wit E, Munster VJ, Schrauwen EJ, Bestebroer TM, Jonges M, Meijer A, Koopmans M, Rimmelzwaan GF, Osterhaus AD, Perez DR, Fouchier RA (2010) Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission. J Virol 84(8):3752–3758
-
(2010)
J Virol
, vol.84
, Issue.8
, pp. 3752-3758
-
-
Herfst, S.1
Chutinimitkul, S.2
Ye, J.3
De Wit, E.4
Munster, V.J.5
Schrauwen, E.J.6
Bestebroer, T.M.7
Jonges, M.8
Meijer, A.9
Koopmans, M.10
Rimmelzwaan, G.F.11
Osterhaus, A.D.12
Perez, D.R.13
Fouchier, R.A.14
-
43
-
-
84862618108
-
Airborne transmission of influenza A/H5N1 virus between ferrets
-
Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, Fouchier RA (2012) Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336(6088): 1534–1541
-
(2012)
Science
, vol.336
, Issue.6088
, pp. 1534-1541
-
-
Herfst, S.1
Schrauwen, E.J.2
Linster, M.3
Chutinimitkul, S.4
De Wit, E.5
Munster, V.J.6
Sorrell, E.M.7
Bestebroer, T.M.8
Burke, D.F.9
Smith, D.J.10
Rimmelzwaan, G.F.11
Osterhaus, A.D.12
Fouchier, R.A.13
-
44
-
-
84857468667
-
Human-like PB2 627K influenza virus polymerase activity is regulated by importin-alpha1 and -alpha7
-
Hudjetz B, Gabriel G (2012) Human-like PB2 627K influenza virus polymerase activity is regulated by importin-alpha1 and -alpha7. PLoS Pathog 8(1):e1002488
-
(2012)
Plos Pathog
, vol.8
, Issue.1
-
-
Hudjetz, B.1
Gabriel, G.2
-
45
-
-
84885141603
-
Transport of the influenza virus genome from nucleus to nucleus
-
Hutchinson EC, Fodor E (2013) Transport of the influenza virus genome from nucleus to nucleus. Viruses 5(10):2424–2446
-
(2013)
Viruses
, vol.5
, Issue.10
, pp. 2424-2446
-
-
Hutchinson, E.C.1
Fodor, E.2
-
46
-
-
84861394598
-
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
-
Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y (2012) Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 486(7403):420–428
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 420-428
-
-
Imai, M.1
Watanabe, T.2
Hatta, M.3
Das, S.C.4
Ozawa, M.5
Shinya, K.6
Zhong, G.7
Hanson, A.8
Katsura, H.9
Watanabe, S.10
Li, C.11
Kawakami, E.12
Yamada, S.13
Kiso, M.14
Suzuki, Y.15
Maher, E.A.16
Neumann, G.17
Kawaoka, Y.18
-
47
-
-
77957757095
-
Influenza a virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1
-
Iwai A, Shiozaki T, Kawai T, Akira S, Kawaoka Y, Takada A, Kida H, Miyazaki T (2010) Influenza a virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1. J Biol Chem 285(42):32064–32074
-
(2010)
J Biol Chem
, vol.285
, Issue.42
, pp. 32064-32074
-
-
Iwai, A.1
Shiozaki, T.2
Kawai, T.3
Akira, S.4
Kawaoka, Y.5
Takada, A.6
Kida, H.7
Miyazaki, T.8
-
48
-
-
84969190151
-
Innate immunity
-
In: Webster R, Monto A, Braciale T, Lamb R, Wiley-Blackwell, UK
-
Iwasaki A, Peiris M (2013) Innate immunity. In: Webster R, Monto A, Braciale T, Lamb R (eds) Textbook of influenza, Wiley-Blackwell, UK, pp 269–282
-
(2013)
Textbook of Influenza
, pp. 269-282
-
-
Iwasaki, A.1
Peiris, M.2
-
49
-
-
84863754680
-
An overlapping protein-coding region in influenza a virus segment 3 modulates the host response
-
Jagger BW, Wise HM, Kash JC, Walters KA, Wills NM, Xiao YL, Dunfee RL, Schwartzman LM, Ozinsky A, Bell GL, Dalton RM, Lo A, Efstathiou S, Atkins JF, Firth AE, Taubenberger JK, Digard P (2012) An overlapping protein-coding region in influenza a virus segment 3 modulates the host response. Science 337(6091):199–204
-
(2012)
Science
, vol.337
, Issue.6091
, pp. 199-204
-
-
Jagger, B.W.1
Wise, H.M.2
Kash, J.C.3
Walters, K.A.4
Wills, N.M.5
Xiao, Y.L.6
Dunfee, R.L.7
Schwartzman, L.M.8
Ozinsky, A.9
Bell, G.L.10
Dalton, R.M.11
Lo, A.12
Efstathiou, S.13
Atkins, J.F.14
Firth, A.E.15
Taubenberger, J.K.16
Digard, P.17
-
50
-
-
44649108325
-
Analysis of the interaction of influenza virus polymerase complex with human cell factors
-
Jorba N, Juarez S, Torreira E, Gastaminza P, Zamarreno N, Albar JP, Ortin J (2008) Analysis of the interaction of influenza virus polymerase complex with human cell factors. Proteomics 8(10):2077–2088
-
(2008)
Proteomics
, vol.8
, Issue.10
, pp. 2077-2088
-
-
Jorba, N.1
Juarez, S.2
Torreira, E.3
Gastaminza, P.4
Zamarreno, N.5
Albar, J.P.6
Ortin, J.7
-
51
-
-
84876494442
-
Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013
-
Kageyama T, Fujisaki S, Takashita E, Xu H, Yamada S, Uchida Y, Neumann G, Saito T, Kawaoka Y, Tashiro M (2013) Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveill 18(15):20453
-
(2013)
Euro Surveill
, vol.18
, Issue.15
, pp. 20453
-
-
Kageyama, T.1
Fujisaki, S.2
Takashita, E.3
Xu, H.4
Yamada, S.5
Uchida, Y.6
Neumann, G.7
Saito, T.8
Kawaoka, Y.9
Tashiro, M.10
-
52
-
-
76749090540
-
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
-
Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, Heuer D, Becker D, Khalil H, Ogilvie LA, Hess S, Maurer AP, Muller E, Wolff T, Rudel T, Meyer TF (2010) Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature 463(7282):818–822
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 818-822
-
-
Karlas, A.1
Machuy, N.2
Shin, Y.3
Pleissner, K.P.4
Artarini, A.5
Heuer, D.6
Becker, D.7
Khalil, H.8
Ogilvie, L.A.9
Hess, S.10
Maurer, A.P.11
Muller, E.12
Wolff, T.13
Rudel, T.14
Meyer, T.F.15
-
53
-
-
77951043137
-
Role of hostspecific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice
-
Kim JH, Hatta M, Watanabe S, Neumann G, Watanabe T, Kawaoka Y (2010) Role of hostspecific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice. J Gen Virol 91(Pt 5):1284–1289
-
(2010)
J Gen Virol
, vol.91
, pp. 1284-1289
-
-
Kim, J.H.1
Hatta, M.2
Watanabe, S.3
Neumann, G.4
Watanabe, T.5
Kawaoka, Y.6
-
54
-
-
76749108989
-
Human host factors required for influenza virus replication
-
Konig R, Stertz S, Zhou Y, Inoue A, Hoffmann HH, Bhattacharyya S, Alamares JG, Tscherne DM, Ortigoza MB, Liang Y, Gao Q, Andrews SE, Bandyopadhyay S, De Jesus P, Tu BP, Pache L, Shih C, Orth A, Bonamy G, Miraglia L, Ideker T, Garcia-Sastre A, Young JA, Palese P, Shaw ML, Chanda SK (2010) Human host factors required for influenza virus replication. Nature 463(7282):813–817
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 813-817
-
-
Konig, R.1
Stertz, S.2
Zhou, Y.3
Inoue, A.4
Hoffmann, H.H.5
Bhattacharyya, S.6
Alamares, J.G.7
Tscherne, D.M.8
Ortigoza, M.B.9
Liang, Y.10
Gao, Q.11
Rews, S.E.12
Bandyopadhyay, S.13
De Jesus, P.14
Tu, B.P.15
Pache, L.16
Shih, C.17
Orth, A.18
Bonamy, G.19
Miraglia, L.20
Ideker, T.21
Garcia-Sastre, A.22
Young, J.A.23
Palese, P.24
Shaw, M.L.25
Chanda, S.K.26
more..
-
55
-
-
84883076935
-
The virus genome and its replication, 2nd edn
-
In: Webster RG, Monto AS, Braciale TJ, and Lamb R, Wiley-Blackwell, UK
-
Krug RM, Fodor E (2013) The virus genome and its replication, 2nd edn. In: Webster RG, Monto AS, Braciale TJ, and Lamb R (eds) Textbook of influenza, Wiley-Blackwell, UK, pp 57–66
-
(2013)
Textbook of Influenza
, pp. 57-66
-
-
Krug, R.M.1
Fodor, E.2
-
56
-
-
84898469114
-
The NS1 protein: A master regulator of host and viral functions, 2nd edn
-
In: Webster R, Monto A, Braciale T, Lamb R, Wiley-Blackwell, UK
-
Krug RM, Garcia-Sastre A (2013) The NS1 protein: a master regulator of host and viral functions, 2nd edn. In: Webster R, Monto A, Braciale T, Lamb R (eds) Textbook of influenza, Wiley-Blackwell, UK, pp 114–132
-
(2013)
Textbook of Influenza
, pp. 114-132
-
-
Krug, R.M.1
Garcia-Sastre, A.2
-
57
-
-
65449163086
-
Structural basis of the influenza a virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
-
Kuzuhara T, Kise D, Yoshida H, Horita T, Murazaki Y, Nishimura A, Echigo N, Utsunomiya H, Tsuge H (2009a) Structural basis of the influenza a virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. J Biol Chem 284(11):6855–6860
-
(2009)
J Biol Chem
, vol.284
, Issue.11
, pp. 6855-6860
-
-
Kuzuhara, T.1
Kise, D.2
Yoshida, H.3
Horita, T.4
Murazaki, Y.5
Nishimura, A.6
Echigo, N.7
Utsunomiya, H.8
Tsuge, H.9
-
58
-
-
59749090786
-
Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza a virus RNA-dependent RNA polymerase PB2
-
Kuzuhara T, Kise D, Yoshida H, Horita T, Murazaki Y, Utsunomiya H, Tsuge H (2009b) Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza a virus RNA-dependent RNA polymerase PB2. Acta Crystallogr Sect F Struct Biol Cryst Commun 65(Pt 2):144–146
-
(2009)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.65
, pp. 144-146
-
-
Kuzuhara, T.1
Kise, D.2
Yoshida, H.3
Horita, T.4
Murazaki, Y.5
Utsunomiya, H.6
Tsuge, H.7
-
59
-
-
34247565021
-
Hostrange determinants on the PB2 protein of influenza a viruses control the interaction between the viral polymerase and nucleoprotein in human cells
-
Labadie K, Dos Santos Afonso E, Rameix-Welti MA, van der Werf S, Naffakh N (2007) Hostrange determinants on the PB2 protein of influenza a viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Virology 362(2):271–282
-
(2007)
Virology
, vol.362
, Issue.2
, pp. 271-282
-
-
Labadie, K.1
Dos Santos Afonso, E.2
Rameix-Welti, M.A.3
Van Der Werf, S.4
Naffakh, N.5
-
60
-
-
65349192767
-
Selection of H5N1 influenza virus PB2 during replication in humans
-
Le QM, Sakai-Tagawa Y, Ozawa M, Ito M, Kawaoka Y (2009) Selection of H5N1 influenza virus PB2 during replication in humans. J Virol 83(10):5278–5281
-
(2009)
J Virol
, vol.83
, Issue.10
, pp. 5278-5281
-
-
Le, Q.M.1
Sakai-Tagawa, Y.2
Ozawa, M.3
Ito, M.4
Kawaoka, Y.5
-
61
-
-
69349096064
-
Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2
-
Li J, Ishaq M, Prudence M, Xi X, Hu T, Liu Q, Guo D (2009) Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2. Virus Res 144(1–2):123–129
-
(2009)
Virus Res
, vol.144
, Issue.1-2
, pp. 123-129
-
-
Li, J.1
Ishaq, M.2
Prudence, M.3
Xi, X.4
Hu, T.5
Liu, Q.6
Guo, D.7
-
62
-
-
84894584144
-
Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in mice
-
Llompart CM, Nieto A, Rodriguez-Frandsen A (2014) Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in mice. J Virol 88:3443–3454
-
(2014)
J Virol
, vol.88
, pp. 3443-3454
-
-
Llompart, C.M.1
Nieto, A.2
Rodriguez-Frandsen, A.3
-
63
-
-
67749131251
-
Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice
-
Maines TR, Jayaraman A, Belser JA, Wadford DA, Pappas C, Zeng H, Gustin KM, Pearce MB, Viswanathan K, Shriver ZH, Raman R, Cox NJ, Sasisekharan R, Katz JM, Tumpey TM (2009) Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science 325(5939):484–487
-
(2009)
Science
, vol.325
, Issue.5939
, pp. 484-487
-
-
Maines, T.R.1
Jayaraman, A.2
Belser, J.A.3
Wadford, D.A.4
Pappas, C.5
Zeng, H.6
Gustin, K.M.7
Pearce, M.B.8
Viswanathan, K.9
Shriver, Z.H.10
Raman, R.11
Cox, N.J.12
Sasisekharan, R.13
Katz, J.M.14
Tumpey, T.M.15
-
64
-
-
84871007119
-
Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells
-
Manz B, Brunotte L, Reuther P, Schwemmle M (2012) Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells. Nat Commun 3:802
-
(2012)
Nat Commun
, vol.3
-
-
Manz, B.1
Brunotte, L.2
Reuther, P.3
Schwemmle, M.4
-
65
-
-
84880366045
-
Adaptation of avian influenza a virus polymerase in mammals to overcome the host species barrier
-
Manz B, Schwemmle M, Brunotte L (2013) Adaptation of avian influenza a virus polymerase in mammals to overcome the host species barrier. J Virol 87(13):7200–7209
-
(2013)
J Virol
, vol.87
, Issue.13
, pp. 7200-7209
-
-
Manz, B.1
Schwemmle, M.2
Brunotte, L.3
-
66
-
-
0035026051
-
Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses
-
Massin P, van der Werf S, Naffakh N (2001) Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses. J Virol 75(11):5398–5404
-
(2001)
J Virol
, vol.75
, Issue.11
, pp. 5398-5404
-
-
Massin, P.1
Van Der Werf, S.2
Naffakh, N.3
-
67
-
-
33847421368
-
Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches
-
Mayer D, Molawi K, Martinez-Sobrido L, Ghanem A, Thomas S, Baginsky S, Grossmann J, Garcia-Sastre A, Schwemmle M (2007) Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches. J Proteome Res 6(2):672–682
-
(2007)
J Proteome Res
, vol.6
, Issue.2
, pp. 672-682
-
-
Mayer, D.1
Molawi, K.2
Martinez-Sobrido, L.3
Ghanem, A.4
Thomas, S.5
Baginsky, S.6
Grossmann, J.7
Garcia-Sastre, A.8
Schwemmle, M.9
-
68
-
-
48649085166
-
An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase
-
Mehle A, Doudna JA (2008) An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase. Cell Host Microbe 4(2):111–122
-
(2008)
Cell Host Microbe
, vol.4
, Issue.2
, pp. 111-122
-
-
Mehle, A.1
Doudna, J.A.2
-
69
-
-
75849136881
-
Adaptive strategies of the influenza virus polymerase for replication in humans
-
Mehle A, Doudna JA (2009) Adaptive strategies of the influenza virus polymerase for replication in humans. Proc Natl Acad Sci U S A 106(50):21312–21316
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.50
, pp. 21312-21316
-
-
Mehle, A.1
Doudna, J.A.2
-
70
-
-
84907442841
-
Structure and function of the influenza virus replication machinery and PB1-F2
-
In: Webster R, Monto A, Braciale T, Lamb R, Wiley-Blackwell, UK
-
Mehle A, McCullers J (2013). Structure and function of the influenza virus replication machinery and PB1-F2. In: Webster R, Monto A, Braciale T, Lamb R (eds) Textbook of influenza, Wiley-Blackwell, UK, pp 133–145
-
(2013)
Textbook of Influenza
, pp. 133-145
-
-
Mehle, A.1
McCullers, J.2
-
71
-
-
84871437653
-
Organization of the influenza virus replication machinery
-
Moeller A, Kirchdoerfer RN, Potter CS, Carragher B, Wilson IA (2012) Organization of the influenza virus replication machinery. Science 338(6114):1631–1634
-
(2012)
Science
, vol.338
, Issue.6114
, pp. 1631-1634
-
-
Moeller, A.1
Kirchdoerfer, R.N.2
Potter, C.S.3
Carragher, B.4
Wilson, I.A.5
-
72
-
-
80052464359
-
Amino acid residues 253 and 591 of the PB2 protein of avian influenza virus A H9N2 contribute to mammalian pathogenesis
-
Mok CK, Yen HL, Yu MY, Yuen KM, Sia SF, Chan MC, Qin G, Tu WW, Peiris JS (2011) Amino acid residues 253 and 591 of the PB2 protein of avian influenza virus A H9N2 contribute to mammalian pathogenesis. J Virol 85(18):9641–9645
-
(2011)
J Virol
, vol.85
, Issue.18
, pp. 9641-9645
-
-
Mok, C.K.1
Yen, H.L.2
Yu, M.Y.3
Yuen, K.M.4
Sia, S.F.5
Chan, M.C.6
Qin, G.7
Tu, W.W.8
Peiris, J.S.9
-
73
-
-
77956839458
-
Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase
-
Moncorge O, Mura M, Barclay WS (2010) Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase. J Virol 84(19):9978–9986
-
(2010)
J Virol
, vol.84
, Issue.19
, pp. 9978-9986
-
-
Moncorge, O.1
Mura, M.2
Barclay, W.S.3
-
74
-
-
67749110449
-
Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets
-
Munster VJ, de Wit E, van den Brand JM, Herfst S, Schrauwen EJ, Bestebroer TM, van de Vijver D, Boucher CA, Koopmans M, Rimmelzwaan GF, Kuiken T, Osterhaus AD, Fouchier RA (2009) Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science 325(5939):481–483
-
(2009)
Science
, vol.325
, Issue.5939
, pp. 481-483
-
-
Munster, V.J.1
De Wit, E.2
Van Den Brand, J.M.3
Herfst, S.4
Schrauwen, E.J.5
Bestebroer, T.M.6
Van De Vijver, D.7
Boucher, C.A.8
Koopmans, M.9
Rimmelzwaan, G.F.10
Kuiken, T.11
Osterhaus, A.D.12
Fouchier, R.A.13
-
75
-
-
0023719126
-
Difference in growth behavior of human, swine, equine, and avian influenza viruses at a high temperature
-
Murakami Y, Nerome K, Yoshioka Y, Mizuno S, Oya A (1988) Difference in growth behavior of human, swine, equine, and avian influenza viruses at a high temperature. Arch Virol 100(3–4):231–244
-
(1988)
Arch Virol
, vol.100
, Issue.3-4
, pp. 231-244
-
-
Murakami, Y.1
Nerome, K.2
Yoshioka, Y.3
Mizuno, S.4
Oya, A.5
-
76
-
-
84874676641
-
Identification of novel influenza a virus proteins translated from PA mRNA
-
Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y (2013) Identification of novel influenza a virus proteins translated from PA mRNA. J Virol 87(5):2455–2462
-
(2013)
J Virol
, vol.87
, Issue.5
, pp. 2455-2462
-
-
Muramoto, Y.1
Noda, T.2
Kawakami, E.3
Akkina, R.4
Kawaoka, Y.5
-
77
-
-
0019975486
-
Virulence of avian influenza a viruses for squirrel monkeys
-
Murphy BR, Hinshaw VS, Sly DL, London WT, Hosier NT, Wood FT, Webster RG, Chanock RM (1982a) Virulence of avian influenza a viruses for squirrel monkeys. Infect Immun 37(3):1119–1126
-
(1982)
Infect Immun
, vol.37
, Issue.3
, pp. 1119-1126
-
-
Murphy, B.R.1
Hinshaw, V.S.2
Sly, D.L.3
London, W.T.4
Hosier, N.T.5
Wood, F.T.6
Webster, R.G.7
Chanock, R.M.8
-
78
-
-
0020425660
-
Reassortant virus derived from avian and human influenza a viruses is attenuated and immunogenic in monkeys
-
Murphy BR, Sly DL, Tierney EL, Hosier NT, Massicot JG, London WT, Chanock RM, Webster RG, Hinshaw VS (1982b) Reassortant virus derived from avian and human influenza a viruses is attenuated and immunogenic in monkeys. Science 218(4579):1330–1332
-
(1982)
Science
, vol.218
, Issue.4579
, pp. 1330-1332
-
-
Murphy, B.R.1
Sly, D.L.2
Tierney, E.L.3
Hosier, N.T.4
Massicot, J.G.5
London, W.T.6
Chanock, R.M.7
Webster, R.G.8
Hinshaw, V.S.9
-
79
-
-
33846491250
-
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits
-
Naito T, Momose F, Kawaguchi A, Nagata K (2007) Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits. J Virol 81(3):1339–1349
-
(2007)
J Virol
, vol.81
, Issue.3
, pp. 1339-1349
-
-
Naito, T.1
Momose, F.2
Kawaguchi, A.3
Nagata, K.4
-
80
-
-
54049146687
-
Structure of the influenza virus A H5N1 nucleoprotein: Implications for RNA binding, oligomerization, and vaccine design
-
Ng AK, Zhang H, Tan K, Li Z, Liu JH, Chan PK, Li SM, Chan WY, Au SW, Joachimiak A, Walz T, Wang JH, Shaw PC (2008) Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design. FASEB J 22(10):3638–3647
-
(2008)
FASEB J
, vol.22
, Issue.10
, pp. 3638-3647
-
-
Ng, A.K.1
Zhang, H.2
Tan, K.3
Li, Z.4
Liu, J.H.5
Chan, P.K.6
Li, S.M.7
Chan, W.Y.8
Au, S.W.9
Joachimiak, A.10
Walz, T.11
Wang, J.H.12
Shaw, P.C.13
-
81
-
-
84860526518
-
Influenza polymerase activity correlates with the strength of interaction between nucleoprotein and PB2 through the host-specific residue K/E627
-
Ng AK, Chan WH, Choi ST, Lam MK, Lau KF, Chan PK, Au SW, Fodor E, Shaw PC (2012) Influenza polymerase activity correlates with the strength of interaction between nucleoprotein and PB2 through the host-specific residue K/E627. PLoS One 7(5):e36415
-
(2012)
Plos One
, vol.7
, Issue.5
, pp. 36415
-
-
Ng, A.K.1
Chan, W.H.2
Choi, S.T.3
Lam, M.K.4
Lau, K.F.5
Chan, P.K.6
Au, S.W.7
Fodor, E.8
Shaw, P.C.9
-
82
-
-
50649122962
-
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
-
Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY (2008) The structural basis for an essential subunit interaction in influenza virus RNA polymerase. Nature 454(7208):1127–1131
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1127-1131
-
-
Obayashi, E.1
Yoshida, H.2
Kawai, F.3
Shibayama, N.4
Kawaguchi, A.5
Nagata, K.6
Tame, J.R.7
Park, S.Y.8
-
83
-
-
84858074461
-
Avian influenza a virus PB2 promotes interferon type I inducing properties of a swine strain in porcine dendritic cells
-
Ocana-Macchi M, Ricklin ME, Python S, Monika GA, Stech J, Stech O, Summerfield A (2012) Avian influenza a virus PB2 promotes interferon type I inducing properties of a swine strain in porcine dendritic cells. Virology 427(1):1–9
-
(2012)
Virology
, vol.427
, Issue.1
, pp. 1-9
-
-
Ocana-Macchi, M.1
Ricklin, M.E.2
Python, S.3
Monika, G.A.4
Stech, J.5
Stech, O.6
Summerfield, A.7
-
84
-
-
0028979910
-
NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein
-
O’Neill RE, Palese P (1995) NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein. Virology 206(1):116–125
-
(1995)
Virology
, vol.206
, Issue.1
, pp. 116-125
-
-
O’Neill, R.E.1
Palese, P.2
-
85
-
-
0029130751
-
Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import
-
O’Neill RE, Jaskunas R, Blobel G, Palese P, Moroianu J (1995) Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import. J Biol Chem 270(39):22701–22704
-
(1995)
J Biol Chem
, vol.270
, Issue.39
, pp. 22701-22704
-
-
O’Neill, R.E.1
Jaskunas, R.2
Blobel, G.3
Palese, P.4
Moroianu, J.5
-
86
-
-
84872028152
-
Emerging roles for the influenza a virus nuclear export protein (NEP)
-
Paterson D, Fodor E (2012) Emerging roles for the influenza a virus nuclear export protein (NEP). PLoS Pathog 8(12):e1003019
-
(2012)
Plos Pathog
, vol.8
, Issue.12
-
-
Paterson, D.1
Fodor, E.2
-
87
-
-
84890879650
-
Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoproteinindependent manner
-
Paterson D, te Velthuis AJ, Vreede FT, Fodor E (2014) Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoproteinindependent manner. J Virol 88(1):339–344
-
(2014)
J Virol
, vol.88
, Issue.1
, pp. 339-344
-
-
Paterson, D.1
Te Velthuis, A.J.2
Vreede, F.T.3
Fodor, E.4
-
88
-
-
0033546991
-
Human infection with influenza H9N2
-
Peiris M, Yuen KY, Leung CW, Chan KH, Ip PL, Lai RW, Orr WK, Shortridge KF (1999) Human infection with influenza H9N2. Lancet 354(9182):916–917
-
(1999)
Lancet
, vol.354
, Issue.9182
, pp. 916-917
-
-
Peiris, M.1
Yuen, K.Y.2
Leung, C.W.3
Chan, K.H.4
Ip, P.L.5
Lai, R.W.6
Orr, W.K.7
Shortridge, K.F.8
-
89
-
-
0024784519
-
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
-
Poch O, Sauvaget I, Delarue M, Tordo N (1989) Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J 8(12):3867–3874
-
(1989)
EMBO J
, vol.8
, Issue.12
, pp. 3867-3874
-
-
Poch, O.1
Sauvaget, I.2
Delarue, M.3
Tordo, N.4
-
90
-
-
59749097063
-
Avian Influenza a virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection
-
Rameix-Welti MA, Tomoiu A, Dos Santos Afonso E, van der Werf S, Naffakh N (2009) Avian Influenza a virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection. J Virol 83(3):1320–1331
-
(2009)
J Virol
, vol.83
, Issue.3
, pp. 1320-1331
-
-
Rameix-Welti, M.A.1
Tomoiu, A.2
Dos Santos Afonso, E.3
Van Der Werf, S.4
Naffakh, N.5
-
91
-
-
75749140581
-
RIG-I detects viral genomic RNA during negative-strand RNA virus infection
-
Rehwinkel J, Tan CP, Goubau D, Schulz O, Pichlmair A, Bier K, Robb N, Vreede F, Barclay W, Fodor E, Reis e Sousa C (2010) RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 140(3):397–408
-
(2010)
Cell
, vol.140
, Issue.3
, pp. 397-408
-
-
Rehwinkel, J.1
Tan, C.P.2
Goubau, D.3
Schulz, O.4
Pichlmair, A.5
Bier, K.6
Robb, N.7
Vreede, F.8
Barclay, W.9
Fodor, E.10
Reis E Sousa, C.11
-
92
-
-
84871020431
-
The nuclear import machinery is a determinant of influenza virus host adaptation
-
Resa-Infante P, Gabriel G (2013) The nuclear import machinery is a determinant of influenza virus host adaptation. Bioessays 35(1):23–27
-
(2013)
Bioessays
, vol.35
, Issue.1
, pp. 23-27
-
-
Resa-Infante, P.1
Gabriel, G.2
-
93
-
-
57549086823
-
The host-dependent interaction of alpha-importins with influenza PB2 polymerase subunit is required for virus RNA replication
-
Resa-Infante P, Jorba N, Zamarreno N, Fernandez Y, Juarez S, Ortin J (2008) The host-dependent interaction of alpha-importins with influenza PB2 polymerase subunit is required for virus RNA replication. PLoS One 3(12):e3904
-
(2008)
Plos One
, vol.3
, Issue.12
-
-
Resa-Infante, P.1
Jorba, N.2
Zamarreno, N.3
Fernandez, Y.4
Juarez, S.5
Ortin, J.6
-
94
-
-
79954499474
-
The influenza virus RNA synthesis machine: Advances in its structure and function
-
Resa-Infante P, Jorba N, Coloma R, Ortin J (2011) The influenza virus RNA synthesis machine: advances in its structure and function. RNA Biol 8(2):207–215
-
(2011)
RNA Biol
, vol.8
, Issue.2
, pp. 207-215
-
-
Resa-Infante, P.1
Jorba, N.2
Coloma, R.3
Ortin, J.4
-
95
-
-
84885672963
-
Limited airborne transmission of H7N9 influenza a virus between ferrets
-
Richard M, Schrauwen EJ, de Graaf M, Bestebroer TM, Spronken MI, van Boheemen S, de Meulder D, Lexmond P, Linster M, Herfst S, Smith DJ, van den Brand JM, Burke DF, Kuiken T, Rimmelzwaan GF, Osterhaus AD, Fouchier RA (2013) Limited airborne transmission of H7N9 influenza a virus between ferrets. Nature 501(7468):560–563
-
(2013)
Nature
, vol.501
, Issue.7468
, pp. 560-563
-
-
Richard, M.1
Schrauwen, E.J.2
De Graaf, M.3
Bestebroer, T.M.4
Spronken, M.I.5
Van Boheemen, S.6
De Meulder, D.7
Lexmond, P.8
Linster, M.9
Herfst, S.10
Smith, D.J.11
Van Den Brand, J.M.12
Burke, D.F.13
Kuiken, T.14
Rimmelzwaan, G.F.15
Osterhaus, A.D.16
Fouchier, R.A.17
-
96
-
-
34248397190
-
Influenza virus infection causes specific degradation of the largest subunit of cellular RNA polymerase II
-
Rodriguez A, Perez-Gonzalez A, Nieto A (2007) Influenza virus infection causes specific degradation of the largest subunit of cellular RNA polymerase II. J Virol 81(10):5315–5324
-
(2007)
J Virol
, vol.81
, Issue.10
, pp. 5315-5324
-
-
Rodriguez, A.1
Perez-Gonzalez, A.2
Nieto, A.3
-
97
-
-
70350319190
-
Attenuated strains of influenza a viruses do not induce degradation of RNA polymerase II
-
Rodriguez A, Perez-Gonzalez A, Hossain MJ, Chen LM, Rolling T, Perez-Brena P, Donis R, Kochs G, Nieto A (2009) Attenuated strains of influenza a viruses do not induce degradation of RNA polymerase II. J Virol 83(21):11166–11174
-
(2009)
J Virol
, vol.83
, Issue.21
, pp. 11166-11174
-
-
Rodriguez, A.1
Perez-Gonzalez, A.2
Hossain, M.J.3
Chen, L.M.4
Rolling, T.5
Perez-Brena, P.6
Donis, R.7
Kochs, G.8
Nieto, A.9
-
98
-
-
77749322610
-
Towards an atomic resolution understanding of the influenza virus replication machinery
-
Ruigrok RW, Crepin T, Hart DJ, Cusack S (2010) Towards an atomic resolution understanding of the influenza virus replication machinery. Curr Opin Struct Biol 20(1):104–113
-
(2010)
Curr Opin Struct Biol
, vol.20
, Issue.1
, pp. 104-113
-
-
Ruigrok, R.W.1
Crepin, T.2
Hart, D.J.3
Cusack, S.4
-
99
-
-
33645058912
-
The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/ 04
-
Salomon R, Franks J, Govorkova EA, Ilyushina NA, Yen HL, Hulse-Post DJ, Humberd J, Trichet M, Rehg JE, Webby RJ, Webster RG, Hoffmann E (2006) The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/ 04. J Exp Med 203(3):689–697
-
(2006)
J Exp Med
, vol.203
, Issue.3
, pp. 689-697
-
-
Salomon, R.1
Franks, J.2
Govorkova, E.A.3
Ilyushina, N.A.4
Yen, H.L.5
Hulse-Post, D.J.6
Humberd, J.7
Trichet, M.8
Rehg, J.E.9
Webby, R.J.10
Webster, R.G.11
Hoffmann, E.12
-
100
-
-
72249103485
-
A physical and regulatory map of hostinfluenza interactions reveals pathways in H1N1 infection
-
Shapira SD, Gat-Viks I, Shum BO, Dricot A, de Grace MM, Wu L, Gupta PB, Hao T, Silver SJ, Root DE, Hill DE, Regev A, Hacohen N (2009) A physical and regulatory map of hostinfluenza interactions reveals pathways in H1N1 infection. Cell 139(7):1255–1267
-
(2009)
Cell
, vol.139
, Issue.7
, pp. 1255-1267
-
-
Shapira, S.D.1
Gat-Viks, I.2
Shum, B.O.3
Dricot, A.4
De Grace, M.M.5
Wu, L.6
Gupta, P.B.7
Hao, T.8
Silver, S.J.9
Root, D.E.10
Hill, D.E.11
Regev, A.12
Hacohen, N.13
-
101
-
-
80055073333
-
The host interactome of influenza virus presents new potential targets for antiviral drugs
-
Shaw ML (2011) The host interactome of influenza virus presents new potential targets for antiviral drugs. Rev Med Virol 21(6):358–369
-
(2011)
Rev Med Virol
, vol.21
, Issue.6
, pp. 358-369
-
-
Shaw, M.L.1
-
102
-
-
84885166179
-
Orthomyxoviridae, 6th edn
-
In: Knipe D, Howley P, Lippincott Williams and Wilkins, Philadelphia
-
Shaw M, Palese P (2013) Orthomyxoviridae, 6th edn. In: Knipe D, Howley P (eds) Fields virology, vol 1. Lippincott Williams and Wilkins, Philadelphia, pp 1151–1185
-
(2013)
Fields Virology
, vol.1
, pp. 1151-1185
-
-
Shaw, M.1
Palese, P.2
-
103
-
-
84869136079
-
Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza a virus
-
Shi M, Jagger BW, Wise HM, Digard P, Holmes EC, Taubenberger JK (2012) Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza a virus. J Virol 86(22):12411–12413
-
(2012)
J Virol
, vol.86
, Issue.22
, pp. 12411-12413
-
-
Shi, M.1
Jagger, B.W.2
Wise, H.M.3
Digard, P.4
Holmes, E.C.5
Taubenberger, J.K.6
-
104
-
-
1542315573
-
PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice
-
Shinya K, Hamm S, Hatta M, Ito H, Ito T, Kawaoka Y (2004) PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice. Virology 320(2):258–266
-
(2004)
Virology
, vol.320
, Issue.2
, pp. 258-266
-
-
Shinya, K.1
Hamm, S.2
Hatta, M.3
Ito, H.4
Ito, T.5
Kawaoka, Y.6
-
105
-
-
72849148491
-
Ostrich involvement in the selection of H5N1 influenza virus possessing mammalian-type amino acids in the PB2 protein
-
Shinya K, Makino A, Ozawa M, Kim JH, Sakai-Tagawa Y, Ito M, Le QM, Kawaoka Y (2009) Ostrich involvement in the selection of H5N1 influenza virus possessing mammalian-type amino acids in the PB2 protein. J Virol 83(24):13015–13018
-
(2009)
J Virol
, vol.83
, Issue.24
, pp. 13015-13018
-
-
Shinya, K.1
Makino, A.2
Ozawa, M.3
Kim, J.H.4
Sakai-Tagawa, Y.5
Ito, M.6
Le, Q.M.7
Kawaoka, Y.8
-
106
-
-
80052070252
-
Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza a viruses
-
Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon HI, Park SJ, Kim CJ, Kim H, Webby RJ, Webster RG, Choi YK (2011) Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza a viruses. J Virol 85(13):6275–6286
-
(2011)
J Virol
, vol.85
, Issue.13
, pp. 6275-6286
-
-
Song, M.S.1
Pascua, P.N.2
Lee, J.H.3
Baek, Y.H.4
Park, K.J.5
Kwon, H.I.6
Park, S.J.7
Kim, C.J.8
Kim, H.9
Webby, R.J.10
Webster, R.G.11
Choi, Y.K.12
-
107
-
-
59249096926
-
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N
-
Steel J, Lowen AC, Mubareka S, Palese P (2009) Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N. PLoS Pathog 5(1):e1000252
-
(2009)
Plos Pathog
, vol.5
, Issue.1
-
-
Steel, J.1
Lowen, A.C.2
Mubareka, S.3
Palese, P.4
-
108
-
-
14444284599
-
Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness
-
Subbarao K, Klimov A, Katz J, Regnery H, Lim W, Hall H, Perdue M, Swayne D, Bender C, Huang J, Hemphill M, Rowe T, Shaw M, Xu X, Fukuda K, Cox N (1998) Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 279(5349):393–396
-
(1998)
Science
, vol.279
, Issue.5349
, pp. 393-396
-
-
Subbarao, K.1
Klimov, A.2
Katz, J.3
Regnery, H.4
Lim, W.5
Hall, H.6
Perdue, M.7
Swayne, D.8
Bender, C.9
Huang, J.10
Hemphill, M.11
Rowe, T.12
Shaw, M.13
Xu, X.14
Fukuda, K.15
Cox, N.16
-
109
-
-
0027468737
-
A single amino acid in the PB2 gene of influenza A virus is a determinant of host range
-
Subbarao EK, London W, Murphy BR (1993) A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. J Virol 67(4):1761–1764
-
(1993)
J Virol
, vol.67
, Issue.4
, pp. 1761-1764
-
-
Subbarao, E.K.1
London, W.2
Murphy, B.R.3
-
110
-
-
67649552964
-
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
-
Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY (2009) Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase. EMBO J 28(12):1803–1811
-
(2009)
EMBO J
, vol.28
, Issue.12
, pp. 1803-1811
-
-
Sugiyama, K.1
Obayashi, E.2
Kawaguchi, A.3
Suzuki, Y.4
Tame, J.R.5
Nagata, K.6
Park, S.Y.7
-
111
-
-
64849116933
-
The use of random homozygous gene perturbation to identify novel host-oriented targets for influenza
-
Sui B, Bamba D, Weng K, Ung H, Chang S, Van Dyke J, Goldblatt M, Duan R, Kinch MS, Li WB (2009) The use of random homozygous gene perturbation to identify novel host-oriented targets for influenza. Virology 387(2):473–481
-
(2009)
Virology
, vol.387
, Issue.2
, pp. 473-481
-
-
Sui, B.1
Bamba, D.2
Weng, K.3
Ung, H.4
Chang, S.5
Van Dyke, J.6
Goldblatt, M.7
Duan, R.8
Kinch, M.S.9
Li, W.B.10
-
112
-
-
33847624936
-
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
-
Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ (2007) Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat Struct Mol Biol 14(3):229–233
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.3
, pp. 229-233
-
-
Tarendeau, F.1
Boudet, J.2
Guilligay, D.3
Mas, P.J.4
Bougault, C.M.5
Boulo, S.6
Baudin, F.7
Ruigrok, R.W.8
Daigle, N.9
Ellenberg, J.10
Cusack, S.11
Simorre, J.P.12
Hart, D.J.13
-
113
-
-
50849137828
-
Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit
-
Tarendeau F, Crepin T, Guilligay D, Ruigrok RW, Cusack S, Hart DJ (2008) Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit. PLoS Pathog 4(8):e1000136
-
(2008)
Plos Pathog
, vol.4
, Issue.8
-
-
Tarendeau, F.1
Crepin, T.2
Guilligay, D.3
Ruigrok, R.W.4
Cusack, S.5
Hart, D.J.6
-
114
-
-
78349236605
-
The role of the influenza virus RNA polymerase in host shut-off
-
Vreede FT, Fodor E (2010) The role of the influenza virus RNA polymerase in host shut-off. Virulence 1(5):436–439
-
(2010)
Virulence
, vol.1
, Issue.5
, pp. 436-439
-
-
Vreede, F.T.1
Fodor, E.2
-
115
-
-
70649087924
-
Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells
-
Vreede FT, Chan AY, Sharps J, Fodor E (2010) Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells. Virology 396(1):125–134
-
(2010)
Virology
, vol.396
, Issue.1
, pp. 125-134
-
-
Vreede, F.T.1
Chan, A.Y.2
Sharps, J.3
Fodor, E.4
-
116
-
-
77956528167
-
Cellular networks involved in the influenza virus life cycle
-
Watanabe T, Watanabe S, Kawaoka Y (2010) Cellular networks involved in the influenza virus life cycle. Cell Host Microbe 7(6):427–439
-
(2010)
Cell Host Microbe
, vol.7
, Issue.6
, pp. 427-439
-
-
Watanabe, T.1
Watanabe, S.2
Kawaoka, Y.3
-
117
-
-
67749133883
-
A complicated message: Identification of a novel PB1-related protein translated from influenza a virus segment 2 mRNA
-
Wise HM, Foeglein A, Sun J, Dalton RM, Patel S, Howard W, Anderson EC, Barclay WS, Digard P (2009) A complicated message: identification of a novel PB1-related protein translated from influenza a virus segment 2 mRNA. J Virol 83(16):8021–8031
-
(2009)
J Virol
, vol.83
, Issue.16
, pp. 8021-8031
-
-
Wise, H.M.1
Foeglein, A.2
Sun, J.3
Dalton, R.M.4
Patel, S.5
Howard, W.6
Erson, E.C.7
Barclay, W.S.8
Digard, P.9
-
118
-
-
0027448742
-
Interaction of the amino-terminus of an influenza virus protein with mitochondria
-
Woodfin BM, Kazim AL (1993) Interaction of the amino-terminus of an influenza virus protein with mitochondria. Arch Biochem Biophys 306(2):427–430
-
(1993)
Arch Biochem Biophys
, vol.306
, Issue.2
, pp. 427-430
-
-
Woodfin, B.M.1
Kazim, A.L.2
-
119
-
-
84863158873
-
Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells
-
Xu C, Hu WB, Xu K, He YX, Wang TY, Chen Z, Li TX, Liu JH, Buchy P, Sun B (2012) Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells. J Gen Virol 93(Pt 3):531–540
-
(2012)
J Gen Virol
, vol.93
, pp. 531-540
-
-
Xu, C.1
Hu, W.B.2
Xu, K.3
He, Y.X.4
Wang, T.Y.5
Chen, Z.6
Li, T.X.7
Liu, J.H.8
Buchy, P.9
Sun, B.10
-
120
-
-
77958149212
-
Biological and structural characterization of a host-adapting amino acid in influenza virus
-
Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, Raymond A, Smith E, Stacy R, Nidom CA, Lank SM, Wiseman RW, Bimber BN, O’Connor DH, Neumann G, Stewart LJ, Kawaoka Y (2010) Biological and structural characterization of a host-adapting amino acid in influenza virus. PLoS Pathog 6(8):e1001034
-
(2010)
Plos Pathog
, vol.6
, Issue.8
-
-
Yamada, S.1
Hatta, M.2
Staker, B.L.3
Watanabe, S.4
Imai, M.5
Shinya, K.6
Sakai-Tagawa, Y.7
Ito, M.8
Ozawa, M.9
Watanabe, T.10
Sakabe, S.11
Li, C.12
Kim, J.H.13
Myler, P.J.14
Phan, I.15
Raymond, A.16
Smith, E.17
Stacy, R.18
Nidom, C.A.19
Lank, S.M.20
Wiseman, R.W.21
Bimber, B.N.22
O’Connor, D.H.23
Neumann, G.24
Stewart, L.J.25
Kawaoka, Y.26
more..
-
121
-
-
33845890539
-
The mechanism by which influenza a virus nucleoprotein forms oligomers and binds RNA
-
Ye Q, Krug RM, Tao YJ (2006) The mechanism by which influenza a virus nucleoprotein forms oligomers and binds RNA. Nature 444(7122):1078–1082
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1078-1082
-
-
Ye, Q.1
Krug, R.M.2
Tao, Y.J.3
-
122
-
-
84883124285
-
Biogenesis, assembly, and export of viral messenger ribonucleoproteins in the influenza a virus infected cell
-
York A, Fodor E (2013) Biogenesis, assembly, and export of viral messenger ribonucleoproteins in the influenza a virus infected cell. RNA Biol 10(8):1274–1282
-
(2013)
RNA Biol
, vol.10
, Issue.8
, pp. 1274-1282
-
-
York, A.1
Fodor, E.2
-
123
-
-
84887265188
-
Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus
-
York A, Hengrung N, Vreede FT, Huiskonen JT, Fodor E (2013) Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus. Proc Natl Acad Sci U S A 110(45):E4238–E4245
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.45
-
-
York, A.1
Hengrung, N.2
Vreede, F.T.3
Huiskonen, J.T.4
Fodor, E.5
-
124
-
-
67249100913
-
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
-
Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z, Liu Y (2009) Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature 458(7240):909–913
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 909-913
-
-
Yuan, P.1
Bartlam, M.2
Lou, Z.3
Chen, S.4
Zhou, J.5
He, X.6
Lv, Z.7
Ge, R.8
Li, X.9
Deng, T.10
Fodor, E.11
Rao, Z.12
Liu, Y.13
-
125
-
-
84893485475
-
PB2 588I enhances the 2009 H1N1 pandemic influenza virus virulence by increasing viral replication and exacerbating PB2 inhibition of interferon-beta expression
-
Zhao Z, Yi C, Zhao L, Wang S, Zhou L, Hu Y, Zou W, Chen H, Jin M (2013) PB2 588I enhances the 2009 H1N1 pandemic influenza virus virulence by increasing viral replication and exacerbating PB2 inhibition of interferon-beta expression. J Virol 88(4):2260–2267
-
(2013)
J Virol
, vol.88
, Issue.4
, pp. 2260-2267
-
-
Zhao, Z.1
Yi, C.2
Zhao, L.3
Wang, S.4
Zhou, L.5
Hu, Y.6
Zou, W.7
Chen, H.8
Jin, M.9
-
126
-
-
84879051825
-
Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza a virus
-
Zhou B, Pearce MB, Li Y, Wang J, Mason RJ, Tumpey TM, Wentworth DE (2013a) Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza a virus. PLoS One 8(6):e67616
-
(2013)
Plos One
, vol.8
, Issue.6
-
-
Zhou, B.1
Pearce, M.B.2
Li, Y.3
Wang, J.4
Mason, R.J.5
Tumpey, T.M.6
Wentworth, D.E.7
-
127
-
-
84881173423
-
Biological features of novel avian influenza a (H7N9) virus
-
Zhou J, Wang D, Gao R, Zhao B, Song J, Qi X, Zhang Y, Shi Y, Yang L, Zhu W, Bai T, Qin K, Lan Y, Zou S, Guo J, Dong J, Dong L, Wei H, Li X, Lu J, Liu L, Zhao X, Huang W, Wen L, Bo H, Xin L, Chen Y, Xu C, Pei Y, Yang Y, Zhang X, Wang S, Feng Z, Han J, Yang W, Gao GF, Wu G, Li D, Wang Y, Shu Y (2013b) Biological features of novel avian influenza a (H7N9) virus. Nature 499(7459):500–503
-
(2013)
Nature
, vol.499
, Issue.7459
, pp. 500-503
-
-
Zhou, J.1
Wang, D.2
Gao, R.3
Zhao, B.4
Song, J.5
Qi, X.6
Zhang, Y.7
Shi, Y.8
Yang, L.9
Zhu, W.10
Bai, T.11
Qin, K.12
Lan, Y.13
Zou, S.14
Guo, J.15
Dong, J.16
Dong, L.17
Wei, H.18
Li, X.19
Lu, J.20
Liu, L.21
Zhao, X.22
Huang, W.23
Wen, L.24
Bo, H.25
Xin, L.26
Chen, Y.27
Xu, C.28
Pei, Y.29
Yang, Y.30
Zhang, X.31
Wang, S.32
Feng, Z.33
Han, J.34
Yang, W.35
Gao, G.F.36
Wu, G.37
Li, D.38
Wang, Y.39
Shu, Y.40
more..
|