Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein

Journal of Virology

Volumn 85, Issue 20, 2011, Pages 10691-10698

  Bogs, Jessica ^a   Kalthoff, Donata ^b   Veits, Jutta ^a   Pavlova, Sophia ^a,d   Schwemmle, Martin ^c   Mänz, Benjamin ^c   Mettenleiter, Thomas C ^a   Stech, Jürgen ^a  

^a Federal Research Institute for Animal Health   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; LYSINE; PB2 PROTEIN; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRD; CELL STRAIN; CHICKEN; CLADISTICS; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE MUTATION; GERMANY; HONG KONG; HOST RANGE; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H5N1; LD 50; LETHALITY; MAMMAL; MAMMAL CELL; MOUSE; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; REVERTANT; STRAIN DIFFERENCE; VIROGENESIS; VIRUS CELL INTERACTION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; BIRDS; CELL LINE; CHICKENS; DISEASE MODELS, ANIMAL; FEMALE; HOST SPECIFICITY; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; LETHAL DOSE 50; MICE; MICE, INBRED BALB C; MUTATION, MISSENSE; ORTHOMYXOVIRIDAE INFECTIONS; POULTRY DISEASES; RNA REPLICASE; RODENT DISEASES; SURVIVAL ANALYSIS; VIRAL PROTEINS;

AVES; AVIAN INFLUENZA VIRUS; GALLUS GALLUS; MAMMALIA; MUS;

EID: 80054995402     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00786-11     Document Type: Article

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