PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells

Journal of Virology

Volumn 84, Issue 9, 2010, Pages 4395-4406

  Bussey, Kendra A ^a   Bousse, Tatiana L ^a,b   Desmet, Emily A ^a   Kim, Baek ^a   Takimoto, Toru ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DNA POLYMERASE; PB2 PROTEIN; THREONINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE MUTATION; HOST CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIROGENESIS; VIRUS TITRATION; VIRUS VIRULENCE; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; BODY WEIGHT; CELL LINE; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA, HUMAN; LUNG; MICE; MICE, INBRED BALB C; MUTAGENESIS, SITE-DIRECTED; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL LOAD; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

AVES; INFLUENZA A VIRUS; MAMMALIA; MUS; ORTHOMYXOVIRIDAE;

EID: 77950835010     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02642-09     Document Type: Article

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