Structure of the influenza virus A H5N1 nucleoprotein: Implications for RNA binding, oligomerization, and vaccine design

FASEB Journal

Volumn 22, Issue 10, 2008, Pages 3638-3647

  Ng, Andy Ka Leung ^a   Zhang, Hongmin ^b   Tan, Kemin ^c   Li, Zongli ^b   Liu, Jin Huan ^b   Chan, Paul Kay Sheung ^a   Li, Sui Mui ^a   Chan, Wood Yee ^a   Au, Shannon Wing Ngor ^a   Joachimiak, Andrzej ^c   Walz, Thomas ^b   Wang, Jia Huai ^b   Shaw, Pang Chui ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

Crystal structure; Protein RNA interaction; Trimerization

Indexed keywords

VIRUS NUCLEOPROTEIN; ANTIVIRUS AGENT; CORE PROTEIN; INFLUENZA VACCINE; NUCLEOPROTEIN; RNA;

ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; INFLUENZA VIRUS A H5N1; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RNA BINDING; AMINO ACID SEQUENCE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; IMMUNOLOGY; MOLECULAR GENETICS; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

INFLUENZAVIRUS A;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; MOLECULAR SEQUENCE DATA; NUCLEOPROTEINS; PROTEIN CONFORMATION; RNA; VIRAL CORE PROTEINS;

EID: 54049146687     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.08-112110     Document Type: Article

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