Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus

Nature

Volumn 454, Issue 7208, 2008, Pages 1123-1126

  He, Xiaojing ^a   Zhou, Jie ^a   Bartlam, Mark ^b   Zhang, Rongguang ^c   Ma, Jianyuan ^a   Lou, Zhiyong ^d   Li, Xuemei ^a,d   Li, Jingjing ^a   Joachimiak, Andrzej ^c   Zeng, Zonghao ^a   Ge, Ruowen ^e   Rao, Zihe ^a,b,d   Liu, Yingfang ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b NANKAI UNIVERSITY   (China)

^c Structural Biology Center   (United States)

^d TSINGHUA UNIVERSITY   (China)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; PA PROTEIN; PB1 PROTEIN; RNA POLYMERASE; UNCLASSIFIED DRUG;

CRYSTAL STRUCTURE; ENZYME ACTIVITY; INFLUENZA; MODELING; PATHOGEN; VIRUS;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; ENZYME ACTIVITY; INFLUENZA VIRUS A H5N1; MOLECULAR DOCKING; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; REOVIRUS; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ANIMALS; BINDING SITES; BIRDS; CRYSTALLOGRAPHY, X-RAY; INFLUENZA A VIRUS, H5N1 SUBTYPE; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; NUCLEOTIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RNA REPLICASE; VIRAL PROTEINS; VIRUS REPLICATION;

AVES; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; ORTHOREOVIRUS;

EID: 50649089174     PISSN: 00280836     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/nature07120     Document Type: Article

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