The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice

International Immunopharmacology

Volumn 25, Issue 1, 2015, Pages 55-64

  Chen, Tong ^a   Mou, Yi ^a   Tan, Jiani ^a   Wei, Linlin ^a   Qiao, Yixue ^a   Wei, Tingting ^a   Xiang, Pengjun ^a   Peng, Sixun ^a   Zhang, Yihua ^a   Huang, Zhangjian ^a   Ji, Hui ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

ALI; CDDO Me; LPS; RAW 264.7 cells

Indexed keywords

BARDOXOLONE METHYL; DEXAMETHASONE; I KAPPA B ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NITRIC OXIDE; PROTEIN KINASE B; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; METHYL 2-CYANO-3,12-DIOXOOLEAN-1,9-DIEN-28-OATE; OLEANOLIC ACID; PEROXIDASE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY INFILTRATE; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CELL MOTION; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; HUMAN; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY;

ACUTE LUNG INJURY; ANIMALS; CELL LINE; CELL MOVEMENT; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; OLEANOLIC ACID; PEROXIDASE;

EID: 84921507325     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.01.011     Document Type: Article

References (43)

1. N.M. Reddy, V. Suryanaraya, M.S. Yates, S.R. Kleeberger, P.M. Hassoun, and M. Yamamoto The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice Am J Respir Crit Care Med 180 2009 867 874
2. D. Shi, M. Zheng, Y. Wang, C. Liu, and S. Chen Protective effects and mechanisms of mogroside V on LPS-induced acute lung injury in mice Pharm Biol 52 2014 729 734
3. X. Xie, S. Sun, W. Zhong, L.W. Soromou, X. Zhou, and M. Wei Zingerone attenuates lipopolysaccharide-induced acute lung injury in mice Int Immunopharmacol 19 2014 103 109
4. X. Feng, and A. Jia Protective effect of carvacrol on acute lung injury induced by lipopolysaccharide in mice Inflammation 37 2014 1091 1101
5. S. Kidd, L. Caldwell, M. Dietrich, I. Samudio, E.L. Spaeth, and K. Watson Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo an effect countered by anti-inflammatory treatment Cytotherapy 12 2010 615 625
6. R.K. Thimmulappa, R.J. Fuchs, D. Malhotra, C. Scollick, K. Traore, and J.H. Bream Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils Antioxid Redox Signal 9 2007 1963 1970
7. G. Schabbauer, M. Tencati, B. Pedersen, R. Pawlinski, and N. Mackman PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice Arterioscler Thromb Vasc Biol 24 2004 1963 1969
8. W.S. Park, W.K. Jung, D.Y. Lee, C. Moon, S.S. Yea, and S.G. Park Cilostazol protects mice against endotoxin shock and attenuates LPS-induced cytokine expression in RAW 264.7 macrophages via MAPK inhibition and NF-kappaB inactivation: not involved in cAMP mechanisms Int Immunopharmacol 10 2010 1077 1085
9. C.M. Park, K.S. Jin, Y.W. Lee, and Y.S. Song Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-kappaB translocation in LPS stimulated RAW 264.7 cells Eur J Pharmacol 660 2011 454 459
10. C.Y. Chen, W.H. Peng, K.D. Tsai, and S.L. Hsu Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages Life Sci 81 2007 1602 1614
11. R. You, W. Long, Z. Lai, L. Sha, K. Wu, and X. Yu Discovery of a potential anti-inflammatory agent: 3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile J Med Chem 56 2013 1984 1995
12. L. Wang, Y. Xu, Q. Yu, Q. Sun, Y. Xu, and Q. Gu H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-kappaB signal pathway Biochem Pharmacol 89 2014 255 265
13. S. Laecke, W. Van Biesen, and R. Vanholder The paradox of bardoxolone methyl: a call for every witness on the stand? Diabetes obes Metab 17 2014 9 14
14. G. Chi, M. Wei, X. Xie, L. Soromou, F. Liu, and S. Zhao Suppression of MAPK and NF-κB pathways by limonene contributes to attenuation of lipopolysaccharide-induced inflammatory responses in acute lung injury Inflammation 36 2013 501 511
15. E. Abraham Neutrophils and acute lung injury Crit Care Med 31 2003 S195 S199
16. J.A. Bastarache, and T.S. Blackwell Development of animal models for the acute respiratory distress syndrome Dis Model Mech 2 2009 218 223
17. Lu.h. S-p, and Chiang C-h Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies J Zhejiang Univ Sci B 8 2007 60 69
18. G. Chi, M. Wei, X. Xie, L.W. Soromou, F. Liu, and S. Zhao Suppression of MAPK and NF-κB pathways by limonene contributes to attenuation of lipopolysaccharide-induced inflammatory responses in acute lung injury Inflammation 36 2012 501 511
19. I.A. Giebelen, D.J. van Westerloo, G.J. LaRosa, A.F. de Vos, and T. van der Poll Local stimulation of [alpha] 7 cholinergic receptors inhibits LPS-induced TNF-[alpha] release in the mouse lung Shock 28 2007 700 703
20. M. Huo, R. Gao, L. Jiang, X. Cui, L. Duan, and X. Deng Suppression of LPS-induced inflammatory responses by gossypol in RAW 264.7 cells and mouse models Int Immunopharmacol 15 2013 442 449
21. M. Romano, M. Sironi, C. Toniatti, N. Polentarutti, P. Fruscella, and P. Ghezzi Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment Immunity 6 1997 315 325
22. T. Geiser, K. Atabai, P.-H. Jarreau, L.B. Ware, J. Pugin, and M.A. Matthay Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1 β-dependent mechanism Am J Respir Crit Care Med 163 2001 1384 1388
23. X. Zhang, J. Li, C. Chen, X. Ci, Q. Yu, and X. Zhang Protective effect of abamectin on acute lung injury induced by lipopolysaccharide in mice Fundam Clin Pharmacol 25 2011 700 707
24. W.L. Lee, and G.P. Downey Neutrophil activation and acute lung injury Curr Opin Crit Care 7 2001 1 7
25. M. Bhatia, and S. Moochhala Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome J Pathol 202 2004 145 156
26. R. Yang, L. Yang, X. Shen, W. Cheng, B. Zhao, and K.H. Ali Suppression of NF-kappaB pathway by crocetin contributes to attenuation of lipopolysaccharide-induced acute lung injury in mice Eur J Pharmacol 674 2012 391 396
27. B. Zhang, Z.Y. Liu, Y.Y. Li, Y. Luo, M.L. Liu, and H.Y. Dong Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice Eur J Pharm Sci 44 2011 573 579
28. S.J. Klebanoff Myeloperoxidase: friend and foe J Leukoc Biol 77 2005 598 625
29. L. Li, A. Hsu, and P.K. Moore Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation - a tale of three gases! Pharmacol Ther 123 2009 386 400
30. M.J. Sung, M. Davaatseren, W. Kim, S.K. Park, S.-H. Kim, and H.J. Hur Vitisin A suppresses LPS-induced NO production by inhibiting ERK, p38, and NF-κB activation in RAW 264.7 cells Int Immunopharmacol 9 2009 319 323
31. K.M. Ardeshna, A.R. Pizzey, S. Devereux, and A. Khwaja The PI3 kinase, p38 SAP kinase, and NF-κB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells Blood 96 2000 1039 1046
32. C.-Y. Chen, W.-H. Peng, K.-D. Tsai, and S.-L. Hsu Luteolin suppresses inflammation-associated gene expression by blocking NF-κB and AP-1 activation pathway in mouse alveolar macrophages Life Sci 81 2007 1602 1614
33. T. Wang, X. Zhang, and J.J. Li The role of NF-κB in the regulation of cell stress responses Int Immunopharmacol 2 2002 1509 1520
34. R.G. Baker, M.S. Hayden, and S. Ghosh NF-κB, inflammation, and metabolic disease Cell Metab 13 2011 11 22
35. K.-N. Kim, Y.-J. Ko, M.-C. Kang, H.-M. Yang, S.W. Roh, and T. Oda Anti-inflammatory effects of trans-1, 3-diphenyl-2, 3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages Food Chem Toxicol 53 2013 371 375
36. W.-J. Yoon, S.-J. Heo, S.-C. Han, H.-J. Lee, G.-J. Kang, and H.-K. Kang Anti-inflammatory effect of sargachromanol G isolated from Sargassum siliquastrum in RAW 264.7 cells Arch Pharm Res 35 2012 1421 1430
37. T. Yu, Y.J. Lee, H.J. Jang, A.R. Kim, S. Hong, and T.W. Kim Anti-inflammatory activity of Sorbus commixta water extract and its molecular inhibitory mechanism J Ethnopharmacol 134 2011 493 500
38. W.F. Chiou, M.J. Don, J.F. Liao, and B.L. Wei Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IkappaB signaling pathways Eur J Pharmacol 650 2011 102 109
39. N. Sawada, Y. Li, and J.K. Liao Novel aspects of the roles of Rac1 GTPase in the cardiovascular system Curr Opin Pharmacol 10 2010 116 121
40. T. Kuncewicz, P. Balakrishnan, M.B. Snuggs, and B.C. Kone Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages Am J Physiol Renal Physiol 281 2001 F326 F336
41. B. Venkatesan, A.J. Valente, S.D. Prabhu, P. Shanmugam, P. Delafontaine, and B. Chandrasekar EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling J Mol Cell Cardiol 49 2010 655 663
42. O.J. Park, J.Y. Han, J.E. Baik, J.H. Jeon, S.S. Kang, and C.H. Yun Lipoteichoic acid of Enterococcus faecalis induces the expression of chemokines via TLR2 and PAFR signaling pathways J Leukoc Biol 94 2013 1275 1284
43. C. Lee, J.I. Oh, J. Park, J.H. Choi, E.K. Bae, and H.J. Lee TNF alpha mediated IL-6 secretion is regulated by JAK/STAT pathway but not by MEK phosphorylation and AKT phosphorylation in U266 multiple myeloma cells BioMed Res Int 2013 2013 580135