Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways

European Journal of Pharmacology

Volumn 650, Issue 1, 2011, Pages 102-109

  Chiou, Wen Fei ^a,b,c   Don, Ming Jaw ^a   Liao, Jyh Fei ^b   Wei, Bai Lu ^c  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAITUNG UNIVERSITY   (Taiwan)

Author keywords

IKK; INOS; LPS; NF B; PI3K; Psoralidin; Syk

Indexed keywords

2 CYANO N (2,5 DIBROMOPHENYL) 3 HYDROXYCROTONAMIDE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FUROCOUMARIN DERIVATIVE; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PICEATANNOL; PROTEIN KINASE SYK; PROTEIN P85; PSORALIDIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL CULTURE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; INHIBITION KINETICS; MACROPHAGE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BENZOFURANS; CELL LINE; CELL NUCLEUS; COUMARINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 78649736194     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.004     Document Type: Article

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